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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2oyeIM8Prostaglandin G/H synthase 11.14.99.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2oyeIM8Prostaglandin G/H synthase 11.14.99.11.000
3ntgD72Prostaglandin G/H synthase 21.14.99.10.523
4fm5DF0Prostaglandin G/H synthase 21.14.99.10.501
4coxIMNProstaglandin G/H synthase 21.14.99.10.470
1eqhFLPProstaglandin G/H synthase 11.14.99.10.462
1ht834CProstaglandin G/H synthase 11.14.99.10.456
2oyuIMSProstaglandin G/H synthase 11.14.99.10.446
3ln1CELProstaglandin G/H synthase 21.14.99.10.442
3rr3FLRProstaglandin G/H synthase 21.14.99.10.441