scPDB - Distribution of Binding site Similarity values of 2opx entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2opx	DXC	Lactaldehyde dehydrogenase	1.2.1.22

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2opx	DXC	Lactaldehyde dehydrogenase	1.2.1.22	1.000
3nwl	NDP	Catalase	1.11.1.6	0.468
1uwz	THU	Cytidine deaminase	3.5.4.5	0.466
4ddl	0JQ	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.465
1rkp	IBM	cGMP-specific 3',5'-cyclic phosphodiesterase	/	0.458
1nqv	LMZ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.454
2wey	EV1	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.452
3cgt	BCD	Cyclomaltodextrin glucanotransferase	2.4.1.19	0.451
3n61	H4B	Nitric oxide synthase, brain	1.14.13.39	0.450
4dbw	511	Aldo-keto reductase family 1 member C3	/	0.450
1z4i	UMP	5'(3')-deoxyribonucleotidase, mitochondrial	3.1.3	0.449
1dls	MTX	Dihydrofolate reductase	1.5.1.3	0.448
4lrr	CF9	Thymidylate synthase	/	0.446
1mkd	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.444
4iyg	1HU	Strictosidine synthase	4.3.3.2	0.444
1ro9	8BR	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.443
4kq6	DLZ	6,7-dimethyl-8-ribityllumazine synthase	/	0.443
4y6n	UPG	Glucosyl-3-phosphoglycerate synthase	2.4.1.266	0.443
1nqu	RDL	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.440
1yho	TRR	Dihydrofolate reductase	1.5.1.3	0.440
4xp1	LDP	Sodium-dependent dopamine transporter	/	0.440