Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ops | HBQ | Gag-Pol polyprotein | 2.7.7.49 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2ops | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 1.000 | |
| 1tl1 | H18 | Gag-Pol polyprotein | 2.7.7.49 | 0.541 | |
| 1tl3 | H20 | Gag-Pol polyprotein | 2.7.7.49 | 0.535 | |
| 1rt7 | UC4 | Gag-Pol polyprotein | 2.7.7.49 | 0.532 | |
| 1s1t | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.532 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.530 | |
| 1rt5 | UC2 | Gag-Pol polyprotein | 2.7.7.49 | 0.529 | |
| 1s1w | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.518 | |
| 4kko | 1RE | Gag-Pol polyprotein | 2.7.7.49 | 0.514 | |
| 1rt4 | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.512 | |
| 1hnv | TBO | Gag-Pol polyprotein | 2.7.7.49 | 0.511 | |
| 1c1b | GCA | Gag-Pol polyprotein | 2.7.7.49 | 0.509 | |
| 1tkx | GWB | Gag-Pol polyprotein | 2.7.7.49 | 0.504 | |
| 1ikw | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.500 | |
| 4ko0 | JLJ | Gag-Pol polyprotein | 2.7.7.49 | 0.500 | |
| 3mee | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.498 | |
| 3i0r | RT3 | Gag-Pol polyprotein | 2.7.7.49 | 0.495 | |
| 1iky | MSD | Gag-Pol polyprotein | 2.7.7.49 | 0.493 | |
| 1jlg | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.492 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.492 | |
| 2opq | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.491 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.490 | |
| 1hni | AAA | Gag-Pol polyprotein | 2.7.7.49 | 0.489 | |
| 1ikv | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.489 | |
| 1jlq | SBN | Gag-Pol polyprotein | 2.7.7.49 | 0.489 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.488 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.488 | |
| 2vg7 | NNI | Gag-Pol polyprotein | 2.7.7.49 | 0.487 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.484 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.484 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.484 | |
| 1rev | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.483 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.482 | |
| 1fk9 | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.481 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.481 | |
| 1tkz | H16 | Gag-Pol polyprotein | 2.7.7.49 | 0.480 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.480 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 1tkt | H12 | Gag-Pol polyprotein | 2.7.7.49 | 0.479 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.478 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.477 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.477 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4g1q | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.476 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.475 | |
| 1nyx | DRF | Peroxisome proliferator-activated receptor gamma | / | 0.475 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.475 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.475 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.475 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.475 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.474 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.473 | |
| 2ow3 | BIM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.473 | |
| 3dl9 | V2H | Vitamin D 25-hydroxylase | / | 0.472 | |
| 3meg | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.472 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
| 2opr | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.471 | |
| 4id5 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.471 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.471 | |
| 4rw6 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.471 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.470 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 1jlc | FTC | Gag-Pol polyprotein | 2.7.7.49 | 0.469 | |
| 1p7t | ACO | Malate synthase G | / | 0.469 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.469 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.469 | |
| 4ig3 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.469 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.469 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.468 | |
| 4i2p | G73 | Gag-Pol polyprotein | 2.7.7.49 | 0.468 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.467 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.467 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.467 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.466 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.466 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2vn9 | GVD | Calcium/calmodulin-dependent protein kinase type II subunit delta | 2.7.11.17 | 0.465 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.465 | |
| 4ifv | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.465 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.465 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1fm9 | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 1mzn | BM6 | Retinoic acid receptor RXR-alpha | / | 0.464 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.464 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.464 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.462 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.462 | |
| 4kfb | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.461 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.461 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.461 | |
| 4uya | AGS | Mitogen-activated protein kinase kinase kinase 21 | 2.7.11.25 | 0.461 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.461 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.460 | |
| 1knu | YPA | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.460 | |
| 1soz | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.460 | |
| 3mec | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3med | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.460 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.460 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.460 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.460 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.460 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.459 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.459 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.459 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.459 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.459 | |
| 4p6x | HCY | Glucocorticoid receptor | / | 0.459 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.458 | |
| 2d3m | COA | 5,7-dihydroxy-2-methylchromone synthase | 2.3.1.216 | 0.458 | |
| 2rf2 | MRX | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.458 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.458 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.458 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.458 | |
| 3qly | 55V | Uncharacterized protein | / | 0.458 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.458 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.457 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.457 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 4ema | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.457 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.457 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.457 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.456 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.456 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.456 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.455 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.455 | |
| 4boe | CLR | Japanin | / | 0.455 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.454 | |
| 1sm2 | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.453 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.453 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.453 | |
| 3h6k | 33T | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.453 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.452 | |
| 4xwt | U5P | Ribonuclease J | / | 0.452 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 1npt | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.451 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.451 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3m8p | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.451 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.451 | |
| 4fsn | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.451 | |
| 4mle | VO1 | Glucokinase | 2.7.1.2 | 0.451 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.450 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.450 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.450 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.450 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.450 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 4bew | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.450 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 2hnd | NVP | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.449 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.449 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3rpn | GTX | Glutathione S-transferase kappa 1 | 2.5.1.18 | 0.449 | |
| 3sr4 | TT8 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.449 | |
| 4h3y | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.449 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.449 | |
| 4qa1 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.449 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.449 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.448 | |
| 1z69 | F42 | 5,10-methylenetetrahydromethanopterin reductase | / | 0.448 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3p3e | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.448 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4iae | 1DX | Alr2278 protein | / | 0.448 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.448 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.448 | |
| 1cm0 | COA | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.447 | |
| 1e7a | PFL | Serum albumin | / | 0.447 | |
| 1eio | GCH | Gastrotropin | / | 0.447 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 1ppj | ANY | Cytochrome b | / | 0.447 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.447 | |
| 2zno | S44 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 3cyl | VIT | Basic phospholipase A2 homolog piratoxin-2 | / | 0.447 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.447 | |
| 3qtu | X44 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.447 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.447 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.447 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.447 | |
| 4jbq | VX6 | Aurora kinase A | 2.7.11.1 | 0.447 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.447 | |
| 1fvt | 106 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1i2l | DCS | Aminodeoxychorismate lyase | 4.1.3.38 | 0.446 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.446 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.446 | |
| 1yin | CM3 | Estrogen receptor | / | 0.446 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.446 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.446 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.446 | |
| 3cs8 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.446 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.446 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.445 | |
| 1eet | BFU | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.445 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 4acd | GR9 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.445 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.444 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.444 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.444 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.444 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2tys | PLT | Tryptophan synthase beta chain | 4.2.1.20 | 0.444 | |
| 2vg5 | NNC | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.444 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.444 | |
| 3fzp | AGS | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.444 | |
| 3iqe | F42 | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.444 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.444 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.444 | |
| 4l8u | 9AZ | Serum albumin | / | 0.444 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.443 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.443 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.443 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3r8z | Z63 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.443 | |
| 4bgh | 3I6 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4ceq | QCH | Integrase | / | 0.443 | |
| 4fki | 09K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.443 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.442 | |
| 1osv | CHC | Bile acid receptor | / | 0.442 | |
| 2d52 | COA | 5,7-dihydroxy-2-methylchromone synthase | 2.3.1.216 | 0.442 | |
| 2won | ZZE | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 3up3 | XCA | aceDAF-12 | / | 0.442 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.442 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.442 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.442 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.441 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.441 | |
| 3b9l | AZZ | Serum albumin | / | 0.441 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.441 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.441 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.441 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.441 | |
| 4nt3 | ZAW | Lactoperoxidase | 1.11.1.7 | 0.441 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.441 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.441 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.440 | |
| 1nq1 | 4HY | Thyroid hormone receptor beta | / | 0.440 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.440 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.440 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.440 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 3h8b | NSY | Cathepsin L1 | 3.4.22.15 | 0.440 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 4bqu | CLR | Japanin | / | 0.440 | |
| 4cf2 | 3GM | Integrase | / | 0.440 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.440 | |
| 4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.440 | |
| 4o7u | THF | Thymidylate synthase | / | 0.440 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.440 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.440 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.440 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 5dt0 | SKE | Aurora kinase A | 2.7.11.1 | 0.440 |