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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.715
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.696
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.691
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.685
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.666
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.656
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.639
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.633
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.610
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.590
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.576
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.575
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.566
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.563
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.562
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.554
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.545
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.534
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.531
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.529
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.525
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.525
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.524
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.520
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.517
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.513
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.511
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.505
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.503
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.500
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.494
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
4qnyANPMitogen activated protein kinase, putative/0.477
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.460
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
4iayADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
3x2uATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3nieANPMitogen-activated protein kinase/0.443