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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.731
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.637
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.632
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.631
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.629
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.596
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.593
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.565
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.556
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.551
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.548
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.530
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.530
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.524
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.517
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.517
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.511
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.511
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.506
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.506
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.503
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.502
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.494
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
4qnyANPMitogen activated protein kinase, putative/0.459
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443