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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2oc4IMHPurine nucleoside phosphorylase2.4.2.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2oc4IMHPurine nucleoside phosphorylase2.4.2.11.000
2on6IMHPurine nucleoside phosphorylase2.4.2.10.638
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.613
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.595
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.551
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.544
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.529
1rszDIHPurine nucleoside phosphorylase2.4.2.10.524
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.524
3k8q22APurine nucleoside phosphorylase2.4.2.10.509
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.496
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.473
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.464
1rctNOSPurine nucleoside phosphorylase2.4.2.10.463
2bf4FADNADPH--cytochrome P450 reductase/0.456
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.454
3imgBZ2Pantothenate synthetase6.3.2.10.452
1a9p9DIPurine nucleoside phosphorylase2.4.2.10.450
3tneRITCandidapepsin-13.4.23.240.449
4lwaQ13Nitric oxide synthase oxygenase1.14.13.1650.449
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.447
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.446
1b8nIMGPurine nucleoside phosphorylase2.4.2.10.445
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.445
2bn4FMNNADPH--cytochrome P450 reductase/0.444
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.443
1bwsNDPGDP-L-fucose synthase/0.441
3s1dZIRCytokinin dehydrogenase 11.5.99.120.441
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.440