scPDB - Distribution of Binding site Similarity values of 2o6h entry / Site 2

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2o6h	INI	6,7-dimethyl-8-ribityllumazine synthase 1	2.5.1.78

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2o6h	INI	6,7-dimethyl-8-ribityllumazine synthase 1	2.5.1.78	1.000
2vi5	Y19	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.528
1w19	T4P	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.488
1w29	TS0	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.488
1w19	T5P	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.487
2a57	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.487
1kyx	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.486
2c94	TSF	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.486
1ejb	INJ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.483
2c9d	PHR	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.470
1w19	T1P	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.460
2c9b	PUG	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.457
1nqu	RDL	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.455
1nqv	LMZ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.451
2c92	TP6	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.448
1rvv	INI	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.443
2chx	090	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.441