scPDB - Distribution of Binding site Similarity values of 2o1x entry / Site 4

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2o1x	TDP	1-deoxy-D-xylulose-5-phosphate synthase	2.2.1.7

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2o1x	TDP	1-deoxy-D-xylulose-5-phosphate synthase	2.2.1.7	1.000
2o1s	TDP	1-deoxy-D-xylulose-5-phosphate synthase	2.2.1.7	0.544
1tkb	N1T	Transketolase 1	2.2.1.1	0.498
1tka	N3T	Transketolase 1	2.2.1.1	0.486
1itz	TPP	Transketolase, chloroplastic	2.2.1.1	0.480
4k9o	TPP	Benzoylformate decarboxylase	4.1.1.7	0.467
1b87	ACO	Aac(6')-Ii protein	/	0.464
1tkc	M6T	Transketolase 1	2.2.1.1	0.464
3upt	TPP	Transketolase	/	0.460
1ngs	TPP	Transketolase 1	2.2.1.1	0.455
1ay0	TPP	Transketolase 1	2.2.1.1	0.454
2r5n	TPP	Transketolase 1	/	0.454
5a4k	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.451
1umc	TDP	2-oxoisovalerate dehydrogenase subunit alpha	1.2.4.4	0.449
1umc	TDP	2-oxoisovalerate dehydrogenase subunit beta	1.2.4.4	0.449
4k9n	TZD	Benzoylformate decarboxylase	4.1.1.7	0.449
3lq2	TDP	Pyruvate dehydrogenase E1 component	1.2.4.1	0.448
2hcd	BIV	Vitamin D3 receptor A	/	0.445
3vt3	VDX	Vitamin D3 receptor	/	0.443
3vt5	YI2	Vitamin D3 receptor	/	0.442
1trk	TPP	Transketolase 1	2.2.1.1	0.441
3sn6	P0G	Beta-2 adrenergic receptor	/	0.441