scPDB - Distribution of Binding site Similarity values of 2lf1 entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2lf1	NDP	Dihydrofolate reductase	1.5.1.3

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2lf1	NDP	Dihydrofolate reductase	1.5.1.3	1.000
1dg8	NDP	Dihydrofolate reductase	1.5.1.3	0.460
4kl9	NDP	Dihydrofolate reductase	1.5.1.3	0.460
1j3k	NDP	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.452
2w3b	NDP	Dihydrofolate reductase	1.5.1.3	0.440