sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 1.000 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.622 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.590 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.588 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.583 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.580 | |
| 1ez4 | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.574 | |
| 3h3f | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.574 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.565 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.562 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.560 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.555 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.554 | |
| 4l4s | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.552 | |
| 4i9h | 1E4 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.546 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.544 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.539 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.534 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.533 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.532 | |
| 1ib6 | NAD | Malate dehydrogenase | / | 0.526 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.522 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.522 | |
| 2cvq | NDP | Malate dehydrogenase | / | 0.522 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.521 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.519 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.514 | |
| 1bmd | NAD | Malate dehydrogenase | / | 0.513 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.513 | |
| 1wzi | NDP | Malate dehydrogenase | / | 0.505 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.505 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.503 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.497 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.493 | |
| 4uun | NAI | L-lactate dehydrogenase | / | 0.493 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.492 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.492 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.491 | |
| 1emd | NAD | Malate dehydrogenase | / | 0.490 | |
| 1y7t | NDP | Malate dehydrogenase | / | 0.490 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.490 | |
| 1hyh | NAD | L-2-hydroxyisocaproate dehydrogenase | / | 0.488 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.488 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.488 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.488 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.486 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.486 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.485 | |
| 3pqf | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.481 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.481 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.480 | |
| 1llq | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.480 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.479 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.477 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.476 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.476 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.475 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.475 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.475 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.474 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.474 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.474 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.473 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.473 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.473 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.473 | |
| 1gv0 | NAD | Malate dehydrogenase | / | 0.472 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.472 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.471 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.471 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.471 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.471 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.471 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.469 | |
| 1qr6 | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.469 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.469 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.468 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.467 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.467 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.467 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.467 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.467 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.467 | |
| 3ieu | GDP | GTPase Era | / | 0.467 | |
| 3zhy | FM6 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.467 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.467 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.466 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.466 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.466 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.466 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.466 | |
| 1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.465 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.465 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.465 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.465 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.464 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.464 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.464 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.464 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.464 | |
| 5a1t | NAI | L-lactate dehydrogenase | / | 0.464 | |
| 1gqt | ACP | Ribokinase | / | 0.463 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.463 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.463 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.463 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.463 | |
| 5a3b | APR | SIR2 family protein | / | 0.463 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.462 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.462 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.462 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.462 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.462 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.462 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.462 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.461 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.461 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.461 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.461 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.461 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.461 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.461 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 4ajn | 88V | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.461 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.461 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.461 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.461 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.461 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.461 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.460 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.460 | |
| 1pzg | A3D | Lactate dehydrogenase | / | 0.460 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.460 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.460 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.460 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.460 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.460 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.459 | |
| 1pzf | A3D | Lactate dehydrogenase | / | 0.459 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.459 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.459 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.459 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.459 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.459 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.459 | |
| 3u9e | COA | Lmo1369 protein | / | 0.459 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.459 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.459 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.458 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.458 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.458 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.458 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.458 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.458 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.458 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.458 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.458 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.457 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.457 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.457 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.457 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.457 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.457 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.457 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.457 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.457 | |
| 5a3c | NAD | SIR2 family protein | / | 0.457 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.456 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.456 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.456 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.456 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 2y4g | TIR | TamL | / | 0.456 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.456 | |
| 3enk | UPG | UDP-glucose 4-epimerase | / | 0.456 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.456 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.456 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1ie3 | NAD | Malate dehydrogenase | / | 0.455 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.455 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.455 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.455 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.455 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.455 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.455 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.455 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.455 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.454 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.454 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.454 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.454 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.454 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.454 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.454 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.454 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.454 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.453 | |
| 1hf3 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.453 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.453 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.453 | |
| 2o12 | FMN | Chorismate synthase | / | 0.453 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.453 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.453 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.453 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.452 | |
| 1o6z | NAD | Malate dehydrogenase | / | 0.452 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.452 | |
| 2e16 | SAH | Diphthine synthase | / | 0.452 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.452 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.452 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.452 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.452 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.452 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.452 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.452 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.451 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.451 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.451 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.451 | |
| 3a3g | DLZ | Lumazine protein | / | 0.451 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.451 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.451 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.451 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.451 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.451 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.451 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.450 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.450 | |
| 1tez | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.450 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.450 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.450 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.450 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.450 | |
| 3rk1 | ATP | N-type ATP pyrophosphatase superfamily | / | 0.450 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.450 | |
| 4ajj | 88R | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.450 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.450 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.450 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.450 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 1nlm | UD1 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | / | 0.449 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.449 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.449 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.449 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.449 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.449 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.449 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.449 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.449 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.449 | |
| 4gll | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.449 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.449 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.449 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.448 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.448 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.448 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.448 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.448 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.448 | |
| 2y8l | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.448 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.448 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.448 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.448 | |
| 3iaa | TYD | CalG2 | / | 0.448 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3pw8 | ACO | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.448 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.448 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.448 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.448 | |
| 4h1v | GNP | Dynamin-1-like protein | 3.6.5.5 | 0.448 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.448 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.448 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.447 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.447 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.447 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.447 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.447 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.447 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.447 | |
| 4ajo | 88N | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.447 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.447 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.447 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.447 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.447 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.446 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.446 | |
| 2f81 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.446 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.446 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.446 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.446 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.446 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.446 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.446 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.446 | |
| 3suf | SUE | Polyprotein | / | 0.446 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.446 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.446 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.446 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4xye | NAD | Formate dehydrogenase | / | 0.446 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.446 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.445 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.445 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.445 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.445 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.445 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.445 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.445 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.445 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.445 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 4azy | 7F3 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.445 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.445 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.445 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.445 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.445 | |
| 4xr9 | NAD | CalS8 | / | 0.445 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 1p9w | ANP | Type II secretion system protein E | / | 0.444 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.444 | |
| 2eeq | SAH | Diphthine synthase | / | 0.444 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.444 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.444 | |
| 2p3b | 3TL | V-1 protease | / | 0.444 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.444 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.444 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.444 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.444 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.444 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.444 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.444 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.444 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.444 | |
| 3s5w | NAP | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.444 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.443 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.443 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.443 | |
| 1men | GAR | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.443 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.443 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.443 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.443 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.443 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.443 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.443 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.443 | |
| 2q0k | NAP | Thioredoxin reductase | 1.8.1.9 | 0.443 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.443 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 3r95 | ACO | MccE protein | / | 0.443 | |
| 3tog | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 4abk | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.443 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4ros | APR | Malate dehydrogenase | / | 0.443 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.443 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.443 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.442 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.442 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.442 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.442 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.442 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.442 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.442 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.442 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.442 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.442 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.442 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.442 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.442 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.442 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.442 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.442 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.442 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.442 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.442 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.442 | |
| 4p63 | NAD | Probable deoxyhypusine synthase | 2.5.1.46 | 0.442 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.442 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.442 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
| 4zol | GTP | Tubulin alpha-1B chain | / | 0.442 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.441 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1rq1 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.441 | |
| 2ejz | SAH | Diphthine synthase | / | 0.441 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.441 | |
| 2hld | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.441 | |
| 2hld | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 2j09 | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
| 2ohv | NHL | Glutamate racemase | / | 0.441 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.441 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.441 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.441 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.441 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.441 | |
| 4tm3 | FAD | KtzI | / | 0.441 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.441 | |
| 4weq | NAP | NAD-dependent dehydrogenase | / | 0.441 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.441 | |
| 5cfl | C2E | Stimulator of interferon genes protein | / | 0.441 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.440 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.440 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.440 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.440 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.440 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.440 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.440 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.440 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.440 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.440 | |
| 3nbv | ANP | Ketohexokinase | / | 0.440 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4b00 | I6X | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4cgi | NZL | Integrase | / | 0.440 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.440 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 5aga | ANP | DNA polymerase theta | / | 0.440 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.440 |