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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2lbvEB4Extracellular fatty acid-binding protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2lbvEB4Extracellular fatty acid-binding protein/1.000
2zbzVDXVitamin D3 dihydroxylase/0.495
5aglH4BNitric oxide synthase, brain1.14.13.390.470
2wd4TBVAscorbate peroxidase/0.453
3zc3NAPFerredoxin--NADP reductase1.18.1.20.448
2d09FLVBiflaviolin synthase CYP158A2/0.446
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.443
3pngH4BNitric oxide synthase, brain1.14.13.390.442
4fvzH4BNitric oxide synthase, brain1.14.13.390.442
5cwa0GAAnthranilate synthase component 14.1.3.270.442
2bxiAZQSerum albumin/0.441