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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2kb2FMNUncharacterized protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2kb2FMNUncharacterized protein/1.000
4y9qC2EUncharacterized protein/0.513
4tx9AMZPhosphoribosyl isomerase A/0.504
1kqnNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.498
4yutFMNFamily 3 adenylate cyclase/0.496
1u2yGOXPancreatic alpha-amylase/0.494
3cppCAMCamphor 5-monooxygenase1.14.15.10.492
2plmSIB5-methylthioadenosine/S-adenosylhomocysteine deaminase3.5.4.280.491
3qyw6PBMitogen-activated protein kinase 12.7.11.240.491
1x0pFADTll0078 protein/0.489
3mziFMNActivator of photopigment and puc expression/0.489
2cchATPCyclin-dependent kinase 22.7.11.220.488
2wpa889Cyclin-dependent kinase 22.7.11.220.488
3gg0FMNUncharacterized protein/0.488
1q3qANPThermosome subunit alpha/0.487
4lj8ADPChaperone protein ClpB/0.487
2bycFMNBlue-light receptor of the BLUF-family/0.485
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
3isjA8DPantothenate synthetase6.3.2.10.484
1w6yEQUSteroid Delta-isomerase5.3.3.10.481
1gebCAMCamphor 5-monooxygenase1.14.15.10.480
3rpy27ZCyclin-dependent kinase 22.7.11.220.480
1py5PY1TGF-beta receptor type-12.7.11.300.479
3gfxFMNUncharacterized protein/0.479
2vtbFADCryptochrome DASH, chloroplastic/mitochondrial/0.478
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.478
4lj7MNTChaperone protein ClpB/0.478
4y93746Tyrosine-protein kinase/0.478
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.476
2ccu2D9Heat shock protein HSP 90-alpha/0.476
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
2hfnFMNActivator of photopigment and puc expression/0.476
2izrBRKCasein kinase I isoform gamma-32.7.11.10.476
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.476
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.476
2cppCAMCamphor 5-monooxygenase1.14.15.10.475
2x3fAPCPantothenate synthetase/0.475
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
2bkzSBCCyclin-dependent kinase 22.7.11.220.473
2qbmCAMCamphor 5-monooxygenase1.14.15.10.473
2vgpAD6Aurora kinase B-A2.7.11.10.473
2xauADPPre-mRNA-splicing factor ATP-dependent RNA helicase PRP433.6.4.130.473
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.473
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.473
1odx0E8Gag-Pol polyprotein3.4.23.160.472
1yrxFMNAppA protein/0.472
2b55D31Cyclin-dependent kinase 22.7.11.220.472
2pja33ZCarboxypeptidase B/0.472
3f8pNADNADH oxidase/thioredoxin reductase/0.472
3v5w8PRBeta-adrenergic receptor kinase 12.7.11.150.472
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.472
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.472
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.472
2eauCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.471
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.471
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.471
2vttLZDCyclin-dependent kinase 22.7.11.220.471
2zwvSAHProbable ribosomal RNA small subunit methyltransferase/0.471
3imeBZ2Pantothenate synthetase6.3.2.10.471
4aicNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.471
4ljaACPChaperone protein ClpB/0.471
1mb9ATPCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.470
2z6iFMN2-nitropropane dioxygenase/0.470
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.470
3gg1FMNUncharacterized protein/0.470
3hqdANPKinesin-like protein KIF11/0.470
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.470
1mrwK57Gag-Pol polyprotein3.4.23.160.469
2zgyGDPPlasmid segregation protein ParM/0.469
3s1cZIRCytokinin dehydrogenase 11.5.99.120.469
4rqzVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.469
3s1h56ZCyclin-dependent kinase 22.7.11.220.468
4be7ATPType I restriction enzyme EcoR124II R protein3.1.21.30.468
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.468
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.467
2bf4FADNADPH--cytochrome P450 reductase/0.467
2x7dEGBKinesin-like protein KIF11/0.467
3lfsA07Cyclin-dependent kinase 22.7.11.220.467
3os33OSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.467
3s2pPMUCyclin-dependent kinase 22.7.11.220.467
4n6hEJ4Delta-type opioid receptor/0.467
4yqfGDPSeptin-9/0.467
1o76CAMCamphor 5-monooxygenase1.14.15.10.466
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
2iyiFMNAppA, antirepressor of ppsR, sensor of blue light/0.466
2j4dFADCryptochrome DASH, chloroplastic/mitochondrial/0.466
3iocA5DPantothenate synthetase6.3.2.10.466
4bqsK2QShikimate kinase2.7.1.710.466
1upuU5PUracil phosphoribosyltransferase/0.465
2pulACPMethylthioribose kinase2.7.1.1000.465
2uzlC94Cyclin-dependent kinase 22.7.11.220.465
3gfyFMNUncharacterized protein/0.465
4ds8A8SAbscisic acid receptor PYL3/0.465
1kqoDNDNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.464
1np7FADCryptochrome DASH/0.464
1rwbNADGlucose 1-dehydrogenase1.1.1.470.464
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
3rmwUPGGlycogenin-12.4.1.1860.464
4fklCK2Cyclin-dependent kinase 22.7.11.220.464
4hjfC2EGGDEF family protein/0.464
4l16ADPFidgetin-like protein 13.6.40.464
1ezvUQ6Cytochrome b/0.463
1h1s4SPCyclin-dependent kinase 22.7.11.220.463
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
2q1l8823-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.463
3fhxPLPPyridoxal kinase2.7.1.350.463
3ral04ZCyclin-dependent kinase 22.7.11.220.463
3t99ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.463
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.463
1ove358Mitogen-activated protein kinase 14/0.462
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.462
1w5wBE4Gag-Pol polyprotein3.4.23.160.462
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.462
2r64740Cyclin-dependent kinase 22.7.11.220.462
4h03LARActin, alpha skeletal muscle/0.462
4jhz1KVBeta-glucuronidase3.2.1.310.462
4mlp2CXCryptochrome-2/0.462
1m9jCLWNitric oxide synthase, endothelial1.14.13.390.461
1vbmYSATyrosine--tRNA ligase6.1.1.10.461
2qbnCAMCamphor 5-monooxygenase1.14.15.10.461
2wipP49Cyclin-dependent kinase 22.7.11.220.461
2y882ERPhosphoribosyl isomerase A5.3.1.160.461
3dneLL1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
3uleC69Actin-related protein 3/0.461
3zxsFADDeoxyribodipyrimidine photolyase-related protein/0.461
4axfANPInositol-pentakisphosphate 2-kinase2.7.1.1580.461
4fkj11KCyclin-dependent kinase 22.7.11.220.461
4gu610NFocal adhesion kinase 12.7.10.20.461
4otyLURProstaglandin G/H synthase 21.14.99.10.461
5br7FADUDP-galactopyranose mutase/0.461
5ekuSAHArginine N-methyltransferase, putative/0.461
1rbmKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.460
2zawCAMCamphor 5-monooxygenase1.14.15.10.460
3gfzFMNUncharacterized protein/0.460
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
3qaiXNNKetohexokinase/0.460
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.460
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.460
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.460
1k6tXN1Gag-Pol polyprotein3.4.23.160.459
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.459
2vwqNAPGlucose 1-dehydrogenase/0.459
3qqlX03Cyclin-dependent kinase 22.7.11.220.459
4a99FADTetX family tetracycline inactivation enzyme/0.459
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.459
4uuxAPRCinA-like protein/0.459
1pdhFASp-hydroxybenzoate hydroxylase/0.458
1qvrANPChaperone protein ClpB/0.458
1rc1KT3Trifunctional purine biosynthetic protein adenosine-32.1.2.20.458
2pmnK51Protein kinase 7/0.458
3r9dX6BCyclin-dependent kinase 22.7.11.220.458
3rkb12ZCyclin-dependent kinase 22.7.11.220.458
4c9pCAMCytochrome P450/0.458
4fa60TAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4o0sADNAurora kinase A2.7.11.10.458
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.458
5jlaNADPutative short-chain dehydrogenase/reductase/0.458
1ckpPVBCyclin-dependent kinase 22.7.11.220.457
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.457
3ddqRRCCyclin-dependent kinase 22.7.11.220.457
3mtfA3FActivin receptor type-12.7.11.300.457
3nwxKVSGag-Pol polyprotein3.4.23.160.457
4ek610KCyclin-dependent kinase 22.7.11.220.457
4hnc0UTMandelate racemase/0.457
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
1g41ADPATP-dependent protease ATPase subunit HslU/0.456
1n2jPAFPantothenate synthetase6.3.2.10.456
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.456
2bf4NAPNADPH--cytochrome P450 reductase/0.456
2p3b3TLV-1 PROTEASE protein/0.456
2p3b3TLV-1 protease/0.456
2qboCAMCamphor 5-monooxygenase1.14.15.10.456
2uzeC95Cyclin-dependent kinase 22.7.11.220.456
2v3aFADRubredoxin-NAD(+) reductase1.18.1.10.456
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.456
2xjgXJGHeat shock protein HSP 90-alpha/0.456
2zjwREFCasein kinase II subunit alpha2.7.11.10.456
3wrjCAMCamphor 5-monooxygenase1.14.15.10.456
4l2iFADElectron transfer flavoprotein alpha/beta-subunit/0.456
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
1q3sADPThermosome subunit alpha/0.455
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.455
1u3dFADCryptochrome-1/0.455
2duv371Cyclin-dependent kinase 22.7.11.220.455
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2vwcBC2ATP-dependent molecular chaperone HSP82/0.455
2zgzGNPPlasmid segregation protein ParM/0.455
3kdiA8SAbscisic acid receptor PYL2/0.455
3lfqA28Cyclin-dependent kinase 22.7.11.220.455
3wdmADN4-phosphopantoate--beta-alanine ligase6.3.2.360.455
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.455
4fv0EK3Mitogen-activated protein kinase 12.7.11.240.455
4hxyNDPPlm1/0.455
4i3zADPCyclin-dependent kinase 22.7.11.220.455
4lj3C2ECyclic di-GMP phosphodiesterase YahA3.1.40.455
4pjjADPUnconventional myosin-VI/0.455
4s26SAHPhosphomethylpyrimidine synthase, chloroplastic4.1.99.170.455
1dssNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.454
1kruIPTGalactoside O-acetyltransferase2.3.1.180.454
1sh9RITGag-Pol polyprotein3.4.23.160.454
1ykr628Cyclin-dependent kinase 22.7.11.220.454
2g226IGRenin3.4.23.150.454
2q3kMUWGag-Pol polyprotein/0.454
2vgoAD5Aurora kinase B-A2.7.11.10.454
2wihP48Cyclin-dependent kinase 22.7.11.220.454
2xy93ESAngiotensin-converting enzyme3.2.10.454
2y9qANPMitogen-activated protein kinase 12.7.11.240.454
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3dqrJI2Nitric oxide synthase, brain1.14.13.390.454
3fvlBHKCarboxypeptidase A13.4.17.10.454
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3qwkX62Cyclin-dependent kinase 22.7.11.220.454
3r28XA0Cyclin-dependent kinase 22.7.11.220.454
4gt3ATPMitogen-activated protein kinase 12.7.11.240.454
4hh0FMNAppA protein/0.454
4r3aRBFBlue-light-activated histidine kinase 22.7.13.30.454
4yswNAIXanthine dehydrogenase/oxidase/0.454
1c1dNAIPhenylalanine dehydrogenase/0.453
1h0w207Cyclin-dependent kinase 22.7.11.220.453
1pxjCK2Cyclin-dependent kinase 22.7.11.220.453
1rfvADPPyridoxal kinase2.7.1.350.453
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.453
2exmZIPCyclin-dependent kinase 22.7.11.220.453
2q0uLABActin, alpha skeletal muscle/0.453
2vtqLZACyclin-dependent kinase 22.7.11.220.453
2zazGK1Mitogen-activated protein kinase 14/0.453
3ag6PAJPantothenate synthetase/0.453
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
3aw9NADNAD-dependent epimerase/dehydratase/0.453
3nwq2NCGag-Pol polyprotein3.4.23.160.453
3nxe2NCProtease/0.453
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.453
3sw418KCyclin-dependent kinase 22.7.11.220.453
3t113T1Gag-Pol polyprotein3.4.23.160.453
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.453
4n0sDHCMitogen-activated protein kinase 12.7.11.240.453
4xgxADPFAD:protein FMN transferase/0.453
5c7oNADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific1.2.1.120.453
1j7uANPAminoglycoside 3'-phosphotransferase2.7.1.950.452
1ke9LS5Cyclin-dependent kinase 22.7.11.220.452
1oi9N20Cyclin-dependent kinase 22.7.11.220.452
1rfuADPPyridoxal kinase2.7.1.350.452
1svmATPLarge T antigen3.6.40.452
1u3cFADCryptochrome-1/0.452
1vh3CMK3-deoxy-manno-octulosonate cytidylyltransferase2.7.7.380.452
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.452
3k3kA8SAbscisic acid receptor PYR1/0.452
3mpt1GKMitogen-activated protein kinase 14/0.452
3nz4TCAPhenylalanine aminomutase (L-beta-phenylalanine forming)/0.452
3pb3SAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.452
3rmf20ZCyclin-dependent kinase 22.7.11.220.452
4bcpT3CCyclin-dependent kinase 22.7.11.220.452
4h1m0YJProtein-tyrosine kinase 2-beta2.7.10.20.452
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.451
1iwiCAMCamphor 5-monooxygenase1.14.15.10.451
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.451
2iw84SPCyclin-dependent kinase 22.7.11.220.451
2uzoC62Cyclin-dependent kinase 22.7.11.220.451
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.451
2vw5BC6ATP-dependent molecular chaperone HSP82/0.451
2w06FRVCyclin-dependent kinase 22.7.11.220.451
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.451
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.451
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3ed1GA3Gibberellin receptor GID1/0.451
3fwfCAMCamphor 5-monooxygenase1.14.15.10.451
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.451
3my5RFZCyclin-dependent kinase 22.7.11.220.451
3ojiPYVAbscisic acid receptor PYL3/0.451
3rk507ZCyclin-dependent kinase 22.7.11.220.451
4asf62UATP-dependent molecular chaperone HSP82/0.451
4b99R4LMitogen-activated protein kinase 72.7.11.240.451
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4j5rA1RO-acetyl-ADP-ribose deacetylase 13.5.10.451
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.451
1dz8CAMCamphor 5-monooxygenase1.14.15.10.450
1fvt106Cyclin-dependent kinase 22.7.11.220.450
1gih1PUCyclin-dependent kinase 22.7.11.220.450
1iidNHMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.450
1ivq0PXGag-Pol polyprotein/0.450
1ja0FMNNADPH--cytochrome P450 reductase/0.450
1m17AQ4Epidermal growth factor receptor2.7.10.10.450
1nfbNADInosine-5'-monophosphate dehydrogenase 2/0.450
1t86CAMCamphor 5-monooxygenase1.14.15.10.450
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.450
2cv2GSUGlutamate--tRNA ligase6.1.1.170.450
2ibzUQ6Cytochrome b/0.450
2vwpNDPGlucose 1-dehydrogenase/0.450
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.450
3rak03ZCyclin-dependent kinase 22.7.11.220.450
3ruqADPChaperonin/0.450
3rusADPChaperonin/0.450
3s00Z60Cyclin-dependent kinase 22.7.11.220.450
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.450
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
4xczFONQdtf/0.450
1aq1STUCyclin-dependent kinase 22.7.11.220.449
1hckATPCyclin-dependent kinase 22.7.11.220.449
1hpxKNIGag-Pol polyprotein/0.449
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
1vyw292Cyclin-dependent kinase 22.7.11.220.449
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2dpmSAMModification methylase DpnIIA2.1.1.720.449
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.449
2hekGDPUncharacterized protein/0.449
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.449
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.449
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2pzrACPFibroblast growth factor receptor 2/0.449
2x2rX2OKinesin-like protein KIF11/0.449
2xszATPRuvB-like 23.6.4.120.449
3n8nN883-dehydroquinate dehydratase4.2.1.100.449
3q92XNBKetohexokinase/0.449
3qxpX64Cyclin-dependent kinase 22.7.11.220.449
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.449
4axdANPInositol-pentakisphosphate 2-kinase2.7.1.1580.449
4cdmFADDeoxyribodipyrimidine photolyase/0.449
4ck2NVUIntegrase/0.449
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.449
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.449
4h0yLARActin, alpha skeletal muscle/0.449
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.449
4lj6ACPChaperone protein ClpB/0.449
4nbuCAA3-oxoacyl-(Acyl-carrier-protein) reductase/0.449
4xvuATPATPase GET3/0.449
4z17PEPEnolase/0.449
5kwvANPPantothenate synthetase/0.449
1cs4FOKAdenylate cyclase type 2/0.448
1cs4FOKAdenylate cyclase type 5/0.448
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
1esqTZPHydroxyethylthiazole kinase/0.448
1k8y13PTryptophan synthase alpha chain/0.448
1l2oADPMyosin heavy chain, striated muscle/0.448
1meiXMPInosine-5'-monophosphate dehydrogenase/0.448
1n77ATPGlutamate--tRNA ligase6.1.1.170.448
1w0xOLOCyclin-dependent kinase 22.7.11.220.448
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.448
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.448
2pywADPMethylthioribose kinase2.7.1.1000.448
2r3kSCQCyclin-dependent kinase 22.7.11.220.448
2x1nX1NCyclin-dependent kinase 22.7.11.220.448
3a5oATPMajor actin/0.448
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.448
3gnqNADGlyceraldehyde-3-phosphate dehydrogenase/0.448
3l63CAMCamphor 5-monooxygenase1.14.15.10.448
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.448
3q2jCKIAminoglycoside 3'-phosphotransferase2.7.1.950.448
3s6gCOAN-acetylglutamate kinase / N-acetylglutamate synthase/0.448
3uli1N3Cyclin-dependent kinase 22.7.11.220.448
3wfjNAD2-dehydropantoate 2-reductase/0.448
4a61ANPPlasmid segregation protein ParM/0.448
4bb3KKAIsopenicillin N synthase1.21.3.10.448
4bcoT6QCyclin-dependent kinase 22.7.11.220.448
4cp4CAMCamphor 5-monooxygenase1.14.15.10.448
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.448
4ivd15TTyrosine-protein kinase JAK1/0.448
4lgaA2OAbscisic acid receptor PYL2/0.448
1geeNADGlucose 1-dehydrogenase1.1.1.470.447
1im2ADPATP-dependent protease ATPase subunit HslU/0.447
1k6vXN2Gag-Pol polyprotein3.4.23.160.447
1kp8AGS60 kDa chaperonin/0.447
1m9k7NINitric oxide synthase, endothelial1.14.13.390.447
1rdwLARActin, alpha skeletal muscle/0.447
1w5yBE6Gag-Pol polyprotein3.4.23.160.447
2acwUPGGlycosyltransferase/0.447
2eb3ANPEpidermal growth factor receptor2.7.10.10.447
2j2pSC2Ficolin-2/0.447
2woeAR6ADP-ribosyl-[dinitrogen reductase] glycohydrolase3.2.2.240.447
2wouZZFTGF-beta receptor type-12.7.11.300.447
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.447
3lxiCAMCytochrome P450/0.447
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.447
3r1sX73Cyclin-dependent kinase 22.7.11.220.447
3r8lZ30Cyclin-dependent kinase 22.7.11.220.447
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.447
4eomATPCyclin-dependent kinase 22.7.11.220.447
4i8qNADPutative betaine aldehyde dehyrogenase/0.447
4kkyCAMCamphor 5-monooxygenase1.14.15.10.447
4l4cCAMCamphor 5-monooxygenase1.14.15.10.447
4l4dCAMCamphor 5-monooxygenase1.14.15.10.447
4zolACPTubulin tyrosine ligase/0.447
1rfqLARActin, alpha skeletal muscle/0.446
1sx4ADP60 kDa chaperonin/0.446
2agvBHQSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.446
2f6rACOBifunctional coenzyme A synthase/0.446
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.446
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.446
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.446
2xikJ60Serine/threonine-protein kinase 252.7.11.10.446
2zbaZBATrichothecene 3-O-acetyltransferase/0.446
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.446
3bqr4RBDeath-associated protein kinase 3/0.446
3ezvEZVCyclin-dependent kinase 22.7.11.220.446
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.446
3fu9KIBLaccase-11.10.3.20.446
3hx4ANPCalmodulin-domain protein kinase 1/0.446
3lm9ADPPutative fructokinase2.7.1.40.446
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.446
3mb714ICasein kinase II subunit alpha2.7.11.10.446
3nmnPYVAbscisic acid receptor PYL1/0.446
3r7eX88Cyclin-dependent kinase 22.7.11.220.446
3sa323XProtease/0.446
3v04V04Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.446
4f640S8Fibroblast growth factor receptor 1/0.446
4fojC2EUncharacterized protein/0.446
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.446
4iji99TGlutathione S-transferase-like protein YibF/0.446
4iyg1HUStrictosidine synthase4.3.3.20.446
4xf7ACPCarbohydrate/pyrimidine kinase, PfkB family/0.446
5hg0SAMPantothenate synthetase/0.446
5dhhDGWNociceptin receptor/0.446
1bozPRDDihydrofolate reductase1.5.1.30.445
1dz6CAMCamphor 5-monooxygenase1.14.15.10.445
1ebk0Q4Gag-Pol polyprotein3.4.23.160.445
1kqmANPMyosin heavy chain, striated muscle/0.445
1me7RVPInosine-5'-monophosphate dehydrogenase/0.445
1oirHDYCyclin-dependent kinase 22.7.11.220.445
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.445
1vikBAYGag-Pol polyprotein/0.445
2cduFADNADH oxidase/0.445
2cvvANPRibonucleoside-diphosphate reductase large chain 11.17.4.10.445
2d4eNAD5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenaseiheyensis HTE831]/0.445
2dbzNAPGlyoxylate reductase1.1.1.260.445
2iw94SPCyclin-dependent kinase 22.7.11.220.445
2q0bACPFibroblast growth factor receptor 2/0.445
2q2zMKKKinesin-like protein KIF11/0.445
2wdzNADGalactitol dehydrogenase/0.445
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3b895GP16S rRNA methylase/0.445
3evbSAHGenome polyprotein2.1.1.560.445
3hv71AUMitogen-activated protein kinase 14/0.445
3k3bL31Kinesin-like protein KIF11/0.445
3prsRITEndothiapepsin3.4.23.220.445
3qrtX14Cyclin-dependent kinase 22.7.11.220.445
3qtwX3ACyclin-dependent kinase 22.7.11.220.445
3ztxZTXAurora kinase B-A2.7.11.10.445
4a0mNADBetaine aldehyde dehydrogenase, chloroplastic1.2.1.80.445
4asg814ATP-dependent molecular chaperone HSP82/0.445
4ei40Q2Tyrosine-protein kinase JAK1/0.445
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.445
4fkr45KCyclin-dependent kinase 22.7.11.220.445
4fr0SAMArsenic methyltransferase/0.445
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.445
4jlt8PRCytochrome P450 2B41.14.14.10.445
4kfgDOODNA gyrase subunit B/0.445
4nj32KDCyclin-dependent kinase 22.7.11.220.445
4pkl1GHUncharacterized protein/0.445
4qnq1XJBcl-2-like protein 1/0.445
1h1pCMGCyclin-dependent kinase 22.7.11.220.444
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
1phePIYCamphor 5-monooxygenase1.14.15.10.444
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.444
1v79FR7Adenosine deaminase3.5.4.40.444
1y5vNE8Queuine tRNA-ribosyltransferase2.4.2.290.444
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.444
2j9mPY8Cyclin-dependent kinase 22.7.11.220.444
2p2jPRXAcetyl-coenzyme A synthetase/0.444
2q6bHR23-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.444
2qn7HBZGlycogen phosphorylase, muscle form2.4.1.10.444
2zaxCAMCamphor 5-monooxygenase1.14.15.10.444
3arqDM5Chitinase A/0.444
3ov4EQUSteroid Delta-isomerase5.3.3.10.444
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.444
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.444
3r7iX9ICyclin-dependent kinase 22.7.11.220.444
3roy22ZCyclin-dependent kinase 22.7.11.220.444
3rpr25ZCyclin-dependent kinase 22.7.11.220.444
3uteFADUDP-galactopyranose mutase/0.444
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.444
4jajXU1Aurora kinase A2.7.11.10.444
4jq8KJ8Epidermal growth factor receptor2.7.10.10.444
4l49CAMCamphor 5-monooxygenase1.14.15.10.444
4nt03DUOrotidine 5'-phosphate decarboxylase4.1.1.230.444
5c1mCLRMu-type opioid receptor/0.444
5d1nSAHUncharacterized protein/0.444
5ikrID8Prostaglandin G/H synthase 21.14.99.10.444
1cjkFOKAdenylate cyclase type 2/0.443
1cjkFOKAdenylate cyclase type 5/0.443
1di8DTQCyclin-dependent kinase 22.7.11.220.443
1e9hINRCyclin-dependent kinase 22.7.11.220.443
1gy3ATPCyclin-dependent kinase 22.7.11.220.443
1idb0DOGag-Pol polyprotein/0.443
1jvdUD1UDP-N-acetylhexosamine pyrophosphorylase2.7.7.230.443
1knpFADL-aspartate oxidase1.4.3.160.443
1mc1PCXCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.443
1pydTDPPyruvate decarboxylase isozyme 1/0.443
1v0pPVBCell division control protein 2 homolog2.7.11.220.443
1zdfUPGGlycogenin-12.4.1.1860.443
1zrzBI1Protein kinase C iota type2.7.11.130.443
2b5vNAPGlucose 1-dehydrogenase/0.443
2cjfRP43-dehydroquinate dehydratase4.2.1.100.443
2gnaGDUUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.443
2r4fRIE3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.443
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.443
3bgcLJHGag-Pol polyprotein3.4.23.160.443
3bhtMFRCyclin-dependent kinase 22.7.11.220.443
3dogNNNCyclin-dependent kinase 22.7.11.220.443
3frqERYErythromycin resistance repressor protein/0.443
3ibqATPPyridoxal kinase/0.443
3imgBZ3Pantothenate synthetase6.3.2.10.443
3ns2PYVAbscisic acid receptor PYL2/0.443
3nup3NUCyclin-dependent kinase 62.7.11.220.443
3od0PCGcGMP-dependent protein kinase 12.7.11.120.443
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
4fko20KCyclin-dependent kinase 22.7.11.220.443
4fyhTR52'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.443
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.443
4jazSTLPeroxisome proliferator-activated receptor gamma/0.443
4nks2M2Fibroblast growth factor receptor 1/0.443
1cf2NAPGlyceraldehyde-3-phosphate dehydrogenase/0.442
1l4mNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.442
1p84UQ6Cytochrome b/0.442
1pxxDIFProstaglandin G/H synthase 21.14.99.10.442
1x98NAPAldose reductase1.1.1.210.442
2a7r5GPGMP reductase 2/0.442
2btsU32Cyclin-dependent kinase 22.7.11.220.442
2jjxATPUridylate kinase/0.442
2qd7065Gag-Pol polyprotein3.4.23.160.442
2r3q5SCCyclin-dependent kinase 22.7.11.220.442
2wb2FADRE11660p/0.442
3cr3ADPPTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.442
3iobA4DPantothenate synthetase6.3.2.10.442
3nhxASDSteroid Delta-isomerase5.3.3.10.442
3o99K13Pol polyprotein/0.442
3p79P79Mitogen-activated protein kinase 14/0.442
4cnjFADL-amino acid oxidase/0.442
4djx0KQBeta-secretase 13.4.23.460.442
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.442
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.442
4ix4ADPUncharacterized protein/0.442
4ki8ADP60 kDa chaperonin/0.442
4yswFADXanthine dehydrogenase/oxidase/0.442
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
5epeSAHUncharacterized protein/0.442
1h5tDAUGlucose-1-phosphate thymidylyltransferase 1/0.441
1hk2T44Serum albumin/0.441
1m9rINENitric oxide synthase, endothelial1.14.13.390.441
1omoNADAlanine dehydrogenase/0.441
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1p4aPCPPur operon repressor/0.441
1td2PXLPyridoxal kinase PdxY/0.441
1w84L12Mitogen-activated protein kinase 14/0.441
1wbtWBTMitogen-activated protein kinase 14/0.441
1xjdSTUProtein kinase C theta type2.7.11.130.441
2btrU73Cyclin-dependent kinase 22.7.11.220.441
2cd8PXICytochrome P450 monooxygenase PikC/0.441
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.441
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.441
2x7eX7EKinesin-like protein KIF11/0.441
3c4zADPRhodopsin kinase/0.441
3d0bSNXHeat shock protein HSP 90-alpha/0.441
3ddpRC8Cyclin-dependent kinase 22.7.11.220.441
3el51UNGag-Pol polyprotein/0.441
3kenZZDKinesin-like protein KIF11/0.441
3orn3ORDual specificity mitogen-activated protein kinase kinase 12.7.12.20.441
3qtsX46Cyclin-dependent kinase 22.7.11.220.441
3qwjX6ACyclin-dependent kinase 22.7.11.220.441
3qzhX69Cyclin-dependent kinase 22.7.11.220.441
3r73X87Cyclin-dependent kinase 22.7.11.220.441
3rm618ZCyclin-dependent kinase 22.7.11.220.441
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.441
3w551FMMitogen-activated protein kinase 12.7.11.240.441
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.441
3zokNAD3-dehydroquinate synthase, chloroplastic4.2.3.40.441
4eoi1ROCyclin-dependent kinase 22.7.11.220.441
4fkg4CKCyclin-dependent kinase 22.7.11.220.441
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.441
4jrnANPRhoptry kinase family protein/0.441
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.441
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.441
5da9AGSUncharacterized protein/0.441
5htpANPProbable sugar kinase/0.441
1bl7SB4Mitogen-activated protein kinase 14/0.440
1c6yMK1Protease/0.440
1cdeDZFPhosphoribosylglycinamide formyltransferase/0.440
1q0bNATKinesin-like protein KIF11/0.440
1qrrUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.440
1sguMK1Gag-Pol polyprotein3.4.23.160.440
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.440
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2b54D05Cyclin-dependent kinase 22.7.11.220.440
2c4g514Cyclin-dependent kinase 22.7.11.220.440
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.440
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.440
2xh9J01Uncharacterized protein/0.440
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.440
3ea0ATPATPase, ParA family/0.440
3fhyATPPyridoxal kinase2.7.1.350.440
3fpbCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.440
3ioeA7DPantothenate synthetase6.3.2.10.440
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.440
3pgiF41Endothiapepsin3.4.23.220.440
3qrsNK8Gag-Pol polyprotein3.4.23.160.440
3r3sNADPutative oxidoreductase/0.440
3t7vSAM3-methylornithine synthase/0.440
3uk6ADPRuvB-like 23.6.4.120.440
3ukuC69Actin-related protein 3/0.440
3zvuA8SAbscisic acid receptor PYR1/0.440
4bz7B3NHistone deacetylase/0.440
4de50JDPantothenate synthetase6.3.2.10.440
4fv6E57Mitogen-activated protein kinase 12.7.11.240.440
4hnf16WCasein kinase I isoform delta2.7.11.10.440
4j33FADKynurenine 3-monooxygenase/0.440
4kb9G79Protease/0.440
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440