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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2jirMGDPeriplasmic nitrate reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2jirMGDPeriplasmic nitrate reductase/1.000
4tvbNADHomospermidine synthase2.5.1.440.519
3sfeFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.512
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.512
4hjoAQ4Epidermal growth factor receptor2.7.10.10.500
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.498
4s26SAHPhosphomethylpyrimidine synthase, chloroplastic4.1.99.170.496
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.494
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.491
1lolXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.490
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.490
2ym2FADPhenylacetone monooxygenase1.14.13.920.490
3nwxKVSGag-Pol polyprotein3.4.23.160.490
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.489
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.489
4plpNADHomospermidine synthase2.5.1.440.489
4oztP1AEcdysone receptor, putative/0.488
2nyaMGDPeriplasmic nitrate reductase1.7.99.40.487
2r0cFADPutative FAD-monooxygenase/0.487
2zu8GDDMannosyl-3-phosphoglycerate synthase2.4.1.2170.486
4xq9NADHomospermidine synthase2.5.1.440.486
3dmeFADPutative conserved exported protein/0.485
3k4cFADPyranose 2-oxidase/0.485
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.484
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.482
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.482
4xqcNADHomospermidine synthase2.5.1.440.482
2ylzFADPhenylacetone monooxygenase1.14.13.920.481
3o26NDPSalutaridine reductase/0.481
4la1FADThioredoxin glutathione reductase/0.481
2gjlFMNNitronate monooxygenase1.13.12.160.480
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.480
3jskAHZThiamine thiazole synthase/0.480
2wotZZGTGF-beta receptor type-12.7.11.300.479
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.479
2c27ACOMycothiol acetyltransferase2.3.1.1890.478
4a6cQG9Gag-Pol polyprotein3.4.23.160.478
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.478
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.478
4j5rA1RO-acetyl-ADP-ribose deacetylase 13.5.10.478
2yutNAPPutative short-chain oxidoreductase/0.477
3ndrNADPyridoxal 4-dehydrogenase1.1.1.1070.477
4u8iFDAUDP-galactopyranose mutase/0.477
4y93746Tyrosine-protein kinase/0.477
4y9lFADAcyl-CoA dehydrogenase family member 11/0.477
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.476
3lovFADProtoporphyrinogen oxidase/0.476
1p0hACOMycothiol acetyltransferase2.3.1.1890.475
2bi4NADLactaldehyde reductase1.1.1.770.475
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.475
3hdyFADUDP-galactopyranose mutase/0.475
4i02CMPcAMP-activated global transcriptional regulator CRP/0.475
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.474
2ylsFADPhenylacetone monooxygenase1.14.13.920.474
2ylxFADPhenylacetone monooxygenase1.14.13.920.474
4a802ANMajor pollen allergen Bet v 1-A/0.474
4xgxADPFAD:protein FMN transferase/0.474
4zohMCNPutative oxidoreductase molybdopterin-binding subunit/0.474
1c0lFADD-amino-acid oxidase1.4.3.30.473
4y95746Tyrosine-protein kinase/0.473
1bv9XV6Gag-Pol polyprotein3.4.23.160.472
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.472
1mrwK57Gag-Pol polyprotein3.4.23.160.472
2ituITQEpidermal growth factor receptor2.7.10.10.472
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.472
2zjmF1MBeta-secretase 13.4.23.460.472
3lsmSFDPyranose 2-oxidase/0.472
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.472
4c02TAKActivin receptor type-12.7.11.300.472
4panGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.472
4xnhACON-terminal acetyltransferase A complex subunit NAT52.3.10.472
5cdtPFBAlcohol dehydrogenase E chain1.1.1.10.472
2d4vNADIsocitrate dehydrogenase [NADP]/0.471
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.471
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.471
3i7eDJRGag-Pol polyprotein/0.471
4ejmNAPPutative zinc-binding dehydrogenase/0.471
4kx6FADFumarate reductase flavoprotein subunit1.3.5.40.471
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.470
2avvMK1Gag-Pol polyprotein3.4.23.160.470
3ryrCMPcAMP-activated global transcriptional regulator CRP/0.470
4d03FADPhenylacetone monooxygenase1.14.13.920.470
4l4xNDPAmphI/0.470
1qvnFRIInterleukin-2/0.469
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.469
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.469
3kybFADUDP-galactopyranose mutase5.4.99.90.469
3vwdACOAlpha-tubulin N-acetyltransferase 1/0.469
4ef9FMNDihydroorotate dehydrogenase (fumarate)/0.469
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.469
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.469
4wucANPDNA gyrase subunit B/0.469
5da9AGSUncharacterized protein/0.469
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.468
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.468
3hk1B64Fatty acid-binding protein, adipocyte/0.468
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.468
1bygSTUTyrosine-protein kinase CSK/0.467
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.467
3mpt1GKMitogen-activated protein kinase 14/0.467
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.467
4fqsLYAThymidylate synthase ThyA/0.467
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.467
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.467
1msnJE2Gag-Pol polyprotein3.4.23.160.466
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.466
2zwaSAHtRNA wybutosine-synthesizing protein 42.1.1.2900.466
3c3nFMNDihydroorotate dehydrogenase (fumarate)1.3.98.10.466
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.466
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.466
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.466
5c3jFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.466
1efvFADElectron transfer flavoprotein subunit alpha, mitochondrial/0.465
2hk9NAPShikimate dehydrogenase (NADP(+))/0.465
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.465
3ibdCPZCytochrome P450 2B61.14.130.465
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.465
4cojDTPUncharacterized protein/0.465
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.465
4lx9ACON-alpha-acetyltransferase2.3.10.465
5dozNDPJamJ/0.465
1eqyATPActin, alpha skeletal muscle/0.464
1gcoNADGlucose 1-dehydrogenase1.1.1.470.464
1nzdUPGDNA beta-glucosyltransferase/0.464
1typFADTrypanothione reductase1.8.1.120.464
2x3nFADProbable FAD-dependent monooxygenase/0.464
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.464
3t99ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.464
4fidGDPG protein alpha subunit, putative/0.464
4gkvNADAlcohol dehydrogenase, propanol-preferring1.1.1.10.464
4l98LRGPeroxisome proliferator-activated receptor gamma/0.464
1c6zROCProtease/0.463
1f0xFADD-lactate dehydrogenase1.1.1.280.463
1qo8FADFumarate reductase flavoprotein subunit/0.463
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
1u2yGOXPancreatic alpha-amylase/0.463
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
2fzwNADAlcohol dehydrogenase class-31.1.1.10.463
2panFADGlyoxylate carboligase4.1.1.470.463
2y6o1N1Ephrin type-A receptor 42.7.10.10.463
3iphG11Mitogen-activated protein kinase 14/0.463
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.463
4a8v2ANMajor pollen allergen Bet v 1-J/0.463
1aztGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.462
1i6xCMPcAMP-activated global transcriptional regulator CRP/0.462
1kf6FADFumarate reductase flavoprotein subunit1.3.5.40.462
1ppjANYCytochrome b/0.462
1qf4RPDAdenylosuccinate synthetase/0.462
2ar8FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.462
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.462
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.462
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.462
3lsiFADPyranose 2-oxidase/0.462
3ukuC69Actin-related protein 3/0.462
4e5kNADPhosphonate dehydrogenase1.20.1.10.462
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.462
5kf8ACOPredicted acetyltransferase/0.462
1bwb146Gag-Pol polyprotein3.4.23.160.461
1h2bNAJNAD-dependent alcohol dehydrogenase/0.461
1lluNADAlcohol dehydrogenase/0.461
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.461
1z6tADPApoptotic protease-activating factor 1/0.461
2bl4NADLactaldehyde reductase1.1.1.770.461
2wbdRO5Fructose-1,6-bisphosphatase 13.1.3.110.461
3b70NAPEnoyl reductase LovC10.461
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.461
3nxxNDPDihydrofolate reductase1.5.1.30.461
4a9rRU5Serine/threonine-protein kinase Chk22.7.11.10.461
4affATPNitrogen regulatory protein P-II/0.461
4gk3L87Ephrin type-A receptor 32.7.10.10.461
4ktc1X3Genome polyprotein3.4.21.980.461
5br7FADUDP-galactopyranose mutase/0.461
1k6tXN1Gag-Pol polyprotein3.4.23.160.460
1w4xFADPhenylacetone monooxygenase1.14.13.920.460
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.460
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.460
2gtmLIDMitogen-activated protein kinase 14/0.460
3eszFMNFlavodoxin/0.460
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.460
3m6gATPActin, alpha skeletal muscle/0.460
3nn6FB06-hydroxy-L-nicotine oxidase/0.460
3sjzGNPTranslation initiation factor 2 subunit gamma/0.460
3w32W32Epidermal growth factor receptor2.7.10.10.460
4a6bQG8Gag-Pol polyprotein3.4.23.160.460
4fr0SAMArsenic methyltransferase/0.460
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.460
4o701QKBromodomain-containing protein 4/0.460
4u0mGTPCyclic GMP-AMP synthase/0.460
4wudANPDNA gyrase subunit B/0.460
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.460
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.460
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.459
2bsxNOSPurine nucleoside phosphorylase/0.459
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.459
2wouZZFTGF-beta receptor type-12.7.11.300.459
3dzvADPHydroxyethylthiazole kinase/0.459
3qvtNAIMyo-inositol-1-phosphate synthase (Ino1)/0.459
3uyk0CXProbable NDP-rhamnosyltransferase/0.459
4a862ANMajor pollen allergen Bet v 1-A/0.459
4ho8UPGGlucose-1-phosphate thymidylyltransferase/0.459
4yntFDAGlucose oxidase, putative/0.459
1h73ANPHomoserine kinase2.7.1.390.458
1jpaANPEphrin type-B receptor 22.7.10.10.458
1m2hAPRNAD-dependent protein deacylase 1/0.458
1mawATPTryptophan--tRNA ligase6.1.1.20.458
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.458
2bfoNDPPteridine reductase 11.5.1.330.458
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.458
2dgnDOIAdenylosuccinate synthetase isozyme 1/0.458
2gsdNADFormate dehydrogenase/0.458
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.458
3dl9BCDVitamin D 25-hydroxylase/0.458
3ea0ATPATPase, ParA family/0.458
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.458
3hx4ANPCalmodulin-domain protein kinase 1/0.458
3ox4NADAlcohol dehydrogenase 21.1.1.10.458
3rf7NADIron-containing alcohol dehydrogenase/0.458
4a2aATPCell division protein FtsA/0.458
4bvbAR6NAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.458
4c58824Cyclin-G-associated kinase2.7.11.10.458
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.458
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.458
4ntcFADThioredoxin reductase gliT/0.458
4oaqNDPR-specific carbonyl reductase/0.458
4weqNAPNAD-dependent dehydrogenase/0.458
4yaiNAIC alpha-dehydrogenase/0.458
5iu86DZAdenosine receptor A2a/0.458
2q4bNAPUncharacterized protein At5g02240/0.457
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.457
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.457
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.457
3aw9NADNAD-dependent epimerase/dehydratase/0.457
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.457
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.457
3oqfS51Renin3.4.23.150.457
3r5yF42Uncharacterized protein/0.457
3w33W19Epidermal growth factor receptor2.7.10.10.457
3w6uNAP6-phosphogluconate dehydrogenase, NAD-binding protein/0.457
4a9tA9TSerine/threonine-protein kinase Chk22.7.11.10.457
4dfg0JVGag-Pol polyprotein3.4.23.160.457
4dieC5PCytidylate kinase/0.457
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.457
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.457
4yswFADXanthine dehydrogenase/oxidase/0.457
5dcyNAPIridoid synthase1.3.1.990.457
1drhNAPDihydrofolate reductase1.5.1.30.456
1knpFADL-aspartate oxidase1.4.3.160.456
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.456
1t7kBH0Gag-Pol polyprotein3.4.23.160.456
2balPQAMitogen-activated protein kinase 14/0.456
2fsvNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.456
2gr2APRFerredoxin reductase/0.456
2h00SAHU6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase/0.456
2ibtNEAModification methylase TaqI2.1.1.720.456
2oapANPType II secretion system protein (GspE-2)/0.456
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.456
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.456
3ac1KZITyrosine-protein kinase Lck2.7.10.20.456
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
3gyeFMNDihydroorotate dehydrogenase (fumarate)/0.456
3lbySAHUncharacterized protein/0.456
3tjzGNPADP-ribosylation factor 1/0.456
3tvuB37Acetyl-CoA carboxylase/0.456
4cf1IY7Integrase/0.456
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.456
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.456
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.456
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.456
4uirFADOleate hydratase4.2.1.530.456
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.456
1i24UPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.455
1mrxK57Gag-Pol polyprotein3.4.23.160.455
1nf7RVPInosine-5'-monophosphate dehydrogenase 2/0.455
1qf5RPLAdenylosuccinate synthetase/0.455
1s7gAPRNAD-dependent protein deacylase 2/0.455
1u7hNADPutative ornithine cyclodeaminase/0.455
1v4sMRKGlucokinase2.7.1.20.455
1xq6NAPUncharacterized protein At5g02240/0.455
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.455
2gr0FADFerredoxin reductase/0.455
2hqmFADGlutathione reductase1.8.1.70.455
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.455
2q61SF1Peroxisome proliferator-activated receptor gamma/0.455
3b2sB2STrichothecene 3-O-acetyltransferase/0.455
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.455
3giyFMN(S)-mandelate dehydrogenase1.1.99.310.455
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.455
3q43D66M1 family aminopeptidase3.4.110.455
3q71AR6Poly [ADP-ribose] polymerase 142.4.2.300.455
3r3sNADPutative oxidoreductase/0.455
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.455
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.455
4dpuAGSMevalonate diphosphate decarboxylase/0.455
4m9aFDAAcyl-CoA dehydrogenase/0.455
4nfhPFBAlcohol dehydrogenase E chain1.1.1.10.455
5kj1PFBAlcohol dehydrogenase E chain1.1.1.10.455
5kjcPFBAlcohol dehydrogenase E chain1.1.1.10.455
1ae1NAPTropinone reductase 1/0.454
1i2bNADUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.454
1knrFADL-aspartate oxidase1.4.3.160.454
1msmJE2Gag-Pol polyprotein3.4.23.160.454
1oc1ASVIsopenicillin N synthase1.21.3.10.454
1upw444Oxysterols receptor LXR-beta/0.454
1yb5NAPQuinone oxidoreductase1.6.5.50.454
2a7r5GPGMP reductase 2/0.454
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.454
2dbqNAPGlyoxylate reductase1.1.1.260.454
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.454
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.454
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.454
2woeAR6ADP-ribosyl-[dinitrogen reductase] glycohydrolase3.2.2.240.454
2yr5FADPhenylalanine 2-monooxygenase precursor1.13.12.90.454
3cukFADD-amino-acid oxidase1.4.3.30.454
3drcMTXDihydrofolate reductase1.5.1.30.454
3gobHXXDdmC/0.454
3jzdNADMaleylacetate reductase/0.454
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.454
4cpdNADAlcohol dehydrogenase/0.454
4ku5DCC3-oxoacyl-[ACP] synthase III/0.454
4nxvGDPMitochondrial dynamics protein MID51/0.454
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.454
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.454
1booSAHModification methylase PvuII2.1.1.1130.453
1e1qADPATP synthase subunit beta, mitochondrial3.6.3.140.453
1fwkADPHomoserine kinase2.7.1.390.453
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.453
1m17AQ4Epidermal growth factor receptor2.7.10.10.453
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.453
1qr0COA4'-phosphopantetheinyl transferase sfp2.7.80.453
2qn7HBZGlycogen phosphorylase, muscle form2.4.1.10.453
3sf6FDAGlutaryl-CoA dehydrogenase/0.453
3tz3B36Acetyl-CoA carboxylase/0.453
4fgrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.453
4ytnFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.453
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.453
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.453
5idwNAPShort-chain dehydrogenase/reductase SDR/0.453
5jydNADShort chain dehydrogenase/0.453
1bxsNADRetinal dehydrogenase 11.2.1.360.452
1c2tGARPhosphoribosylglycinamide formyltransferase/0.452
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.452
1ebdFADDihydrolipoyl dehydrogenase1.8.1.40.452
1jubFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.452
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.452
2djlFMNDihydroorotate dehydrogenase (fumarate)1.3.98.10.452
2hejNDPAldo-keto reductase family 1 member C211.1.10.452
2itwITQEpidermal growth factor receptor2.7.10.10.452
2uxwTH3Very long-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.90.452
2vpyMGDThiosulfate reductase/0.452
2wp5FADTrypanothione reductase/0.452
3epsATPIsocitrate dehydrogenase kinase/phosphatase/0.452
3etgNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.452
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.452
3gy0NAPNAD(P)-dependent oxidoreductase/0.452
3lpkZ76Beta-secretase 13.4.23.460.452
3ms421NGlycogen phosphorylase, muscle form2.4.1.10.452
3oibFDAPutative acyl-CoA dehydrogenase/0.452
3qftNAPNADPH--cytochrome P450 reductase/0.452
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.452
4aa0AA0Mitogen-activated protein kinase 14/0.452
4blsAPCNTPase P4/0.452
4f4qFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.452
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.452
4j33FADKynurenine 3-monooxygenase/0.452
4opiFDAConserved Archaeal protein/0.452
4twnB96Ephrin type-A receptor 32.7.10.10.452
4udrFAD5-(hydroxymethyl)furfural oxidase/0.452
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
5l3rGCPCell division protein FtsY homolog, chloroplastic/0.452
5k2aZMAAdenosine receptor A2a/0.452
1b16NAQAlcohol dehydrogenase1.1.1.10.451
1bwaXV6Gag-Pol polyprotein3.4.23.160.451
1errRALEstrogen receptor/0.451
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.451
1mg5NAIAlcohol dehydrogenase1.1.1.10.451
1npxFADNADH peroxidase1.11.1.10.451
1obnASVIsopenicillin N synthase1.21.3.10.451
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.451
1s22ATPActin, alpha skeletal muscle/0.451
1szfFMNCytochrome b2, mitochondrial1.1.2.30.451
1t2cNAIL-lactate dehydrogenase1.1.1.270.451
1tj0FADBifunctional protein PutA1.5.5.20.451
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.451
2bjhFERFeruloyl esterase A3.1.1.730.451
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.451
2cjfRP43-dehydroquinate dehydratase4.2.1.100.451
2qaeFADDihydrolipoyl dehydrogenase1.8.1.40.451
2qiqCYVReplicase polyprotein 1ab/0.451
2qo6CHDFatty acid-binding protein 10-A, liver basic/0.451
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.451
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.451
2y6fM9FIsopenicillin N synthase1.21.3.10.451
2yvfNADFerredoxin reductase/0.451
2yw2ATPPhosphoribosylamine--glycine ligase/0.451
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.451
3ijrNADOxidoreductase, short chain dehydrogenase/reductase family/0.451
3ioeA7DPantothenate synthetase6.3.2.10.451
3o3pGDDGlycosyl transferase, family 2/0.451
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.451
3sw1FMNSensory box protein/0.451
3uylTYDProbable NDP-rhamnosyltransferase/0.451
3vi5M4MHematopoietic prostaglandin D synthase/0.451
4g6hFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.451
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.451
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.451
5iqeGNPBifunctional AAC/APH2.3.10.451
1c1dNAIPhenylalanine dehydrogenase/0.450
1hzjUD1UDP-glucose 4-epimerase/0.450
1txzAPRProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.450
1y0s331Peroxisome proliferator-activated receptor delta/0.450
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.450
1yc2APRNAD-dependent protein deacylase 2/0.450
1z7eUGABifunctional polymyxin resistance protein ArnA/0.450
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.450
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2g1r3IGRenin3.4.23.150.450
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.450
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.450
2of2547Tyrosine-protein kinase Lck2.7.10.20.450
2pg0FADAcyl-CoA dehydrogenase/0.450
2q0kNAPThioredoxin reductase1.8.1.90.450
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.450
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.450
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.450
2yy7NADL-threonine dehydrogenase/0.450
3bk2U5PRibonuclease J/0.450
3c16GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.450
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.450
3cosNADAlcohol dehydrogenase 41.1.1.10.450
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.450
3sm8FNKFAD-dependent catabolic D-arginine dehydrogenase DauA/0.450
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.450
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.450
4i09CMPcAMP-activated global transcriptional regulator CRP/0.450
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.450
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.450
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.450
4mokFADPyranose 2-oxidase/0.450
4nfsNAJAlcohol dehydrogenase E chain1.1.1.10.450
4w6z8IDAlcohol dehydrogenase 11.1.1.10.450
4yagNAIC alpha-dehydrogenase/0.450
5a3bAPRSIR2 family protein/0.450
1me7MOAInosine-5'-monophosphate dehydrogenase/0.449
1sguMK1Gag-Pol polyprotein3.4.23.160.449
1v9aSAHUncharacterized protein/0.449
2b4yAPRNAD-dependent protein deacylase sirtuin-5, mitochondrial/0.449
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2jk6FADTrypanothione reductase/0.449
2pd7FADVivid PAS protein VVD/0.449
2rghFADAlpha-Glycerophosphate Oxidase/0.449
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.449
3e2sFADBifunctional protein PutA1.5.5.20.449
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
3iaeD7KBenzaldehyde lyase/0.449
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.449
3sheI85MAP kinase-activated protein kinase 32.7.11.10.449
3t9aANPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.449
3tm5SFGUncharacterized protein/0.449
3wmxNADNAD dependent epimerase/dehydratase/0.449
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.449
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.449
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.449
4h4zFADBiphenyl dioxygenase ferredoxin reductase subunit/0.449
4k41ATPActin, alpha skeletal muscle/0.449
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.449
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.449
4q1y017Gag-Pol polyprotein3.4.23.160.449
4wouGDPPhosphoenolpyruvate carboxykinase [GTP]/0.449
5emhNAPIridoid synthase1.3.1.990.449
5uviZMAAdenosine receptor A2a/0.449
1cjuFOKAdenylate cyclase type 2/0.448
1cjuFOKAdenylate cyclase type 5/0.448
1crbRTLRetinol-binding protein 1/0.448
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.448
1fg80Q4Gag-Pol polyprotein3.4.23.160.448
1hncGDNGlutathione S-transferase Mu 22.5.1.180.448
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.448
1me6IVSPlasmepsin-23.4.23.390.448
1o8cNDPProbable acrylyl-CoA reductase AcuI1.3.1.840.448
1suiFRECaffeoyl-CoA O-methyltransferase2.1.1.1040.448
1u3cFADCryptochrome-1/0.448
1w87NAPFerredoxin--NADP reductase1.18.1.20.448
1wntNAPL-xylulose reductase1.1.1.100.448
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.448
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.448
2nadNADFormate dehydrogenase/0.448
2p5uNADUDP-glucose 4-epimerase/0.448
2x3fAPCPantothenate synthetase/0.448
2xgs44PUncharacterized protein/0.448
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.448
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.448
3eyhIZATyrosine-protein kinase JAK1/0.448
3g7jGTXGlutathione transferase GST1-4/0.448
3r83Z14Cyclin-dependent kinase 22.7.11.220.448
3uleC69Actin-related protein 3/0.448
3uqdADPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.448
3w0gW07Vitamin D3 receptor/0.448
3w0iO11Vitamin D3 receptor/0.448
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.448
4dnaFADProbable glutathione reductase/0.448
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.448
4eu5COASuccinyl-CoA:acetate CoA-transferase/0.448
4fcwADPChaperone protein ClpB/0.448
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.448
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.448
4fweFADLysine-specific histone demethylase 1B10.448
4j2wFADKynurenine 3-monooxygenase/0.448
4jk4DIUSerum albumin/0.448
4kf1HT5Aryldialkylphosphatase3.1.8.10.448
4l8u9AZSerum albumin/0.448
4lxhC1EAlpha/beta hydrolase fold/0.448
4rujVDXVitamin D3 receptor A/0.448
4wx1FDAUDP-galactopyranose mutase/0.448
5c3aURMHisto-blood group ABO system transferase/0.448
5dbfNDPIridoid synthase1.3.1.990.448
5ig2NADShort-chain dehydrogenase/reductase SDR/0.448
1culFOKAdenylate cyclase type 2/0.447
1culFOKAdenylate cyclase type 5/0.447
1n5qTNCActVA 6 protein/0.447
1v59FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.447
1vjy460TGF-beta receptor type-12.7.11.300.447
2djxFMNDihydroorotate dehydrogenase (fumarate)1.3.98.10.447
2e1mFADL-glutamate oxidase/0.447
2eiiNAD1-pyrroline-5-carboxylate dehydrogenase/0.447
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
2h3wCOACarnitine O-acetyltransferase2.3.1.70.447
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.447
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.447
2nu9COASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.447
2ohxNADAlcohol dehydrogenase E chain1.1.1.10.447
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.447
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.447
3cobADPKinesin heavy chain-like protein/0.447
3d7kD7KBenzaldehyde lyase/0.447
3eeySAMrRNA methylase/0.447
3kr5BEYM17 leucyl aminopeptidase/0.447
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.447
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.447
3poz03PEpidermal growth factor receptor2.7.10.10.447
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.447
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.447
4bb3KKAIsopenicillin N synthase1.21.3.10.447
4bcsBTNAvidin-related protein 4/5/0.447
4c04SFGProtein arginine N-methyltransferase 6/0.447
4ceqQCHIntegrase/0.447
4e5yNDPGDP-L-fucose synthase1.1.1.2710.447
4fv7E94Mitogen-activated protein kinase 12.7.11.240.447
4i01CMPcAMP-activated global transcriptional regulator CRP/0.447
4jq8KJ8Epidermal growth factor receptor2.7.10.10.447
4kcfAKMFAD-dependent oxidoreductase/0.447
4kin1M8Mitogen-activated protein kinase 14/0.447
4rosAPRMalate dehydrogenase/0.447
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.447
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.447
4v12POGMaoC like domain protein/0.447
4wzhFMNDihydroorotate dehydrogenase (fumarate)/0.447
4x2qNADRetinal dehydrogenase 21.2.1.360.447
5k2bZMAAdenosine receptor A2a/0.447
1c7oPPGHemolysin/0.446
1fbmRTLCartilage oligomeric matrix protein/0.446
1ftlDNQGlutamate receptor 2/0.446
1ie8KH1Vitamin D3 receptor/0.446
1jomFFODihydrofolate reductase1.5.1.30.446
1k6cMK1Gag-Pol polyprotein3.4.23.160.446
1q43CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2/0.446
1tqf32PBeta-secretase 13.4.23.460.446
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.446
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.446
2givACOHistone acetyltransferase KAT8/0.446
2o0uC0MMitogen-activated protein kinase 102.7.11.240.446
2oz6CMPCyclic AMP receptor-like protein/0.446
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.446
2qocANPEphrin type-A receptor 32.7.10.10.446
2rgoFADAlpha-Glycerophosphate Oxidase/0.446
2v52LABActin, alpha skeletal muscle/0.446
2vn0TDZCytochrome P450 2C8/0.446
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.446
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.446
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.446
3frqERYErythromycin resistance repressor protein/0.446
3gqvNAPEnoyl reductase LovC10.446
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
3p8z36AGenome polyprotein2.1.1.560.446
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.446
3ruvANPChaperonin/0.446
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.446
3w0c6DSVitamin D3 receptor/0.446
4c3sNADAldehyde Dehydrogenase/0.446
4gk2L66Ephrin type-A receptor 32.7.10.10.446
4gk4L90Ephrin type-A receptor 32.7.10.10.446
4h03LARActin, alpha skeletal muscle/0.446
4upjU04Gag-Pol polyprotein/0.446
4uyf73BBromodomain-containing protein 2/0.446
4yduADPtRNA N6-adenosine threonylcarbamoyltransferase/0.446
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.446
5fs9FADApoptosis-inducing factor 1, mitochondrial1.1.10.446
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.446
5kczNAJAlcohol dehydrogenase E chain1.1.1.10.446
1ai9NDPDihydrofolate reductase1.5.1.30.445
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.445
1cjkFOKAdenylate cyclase type 2/0.445
1cjkFOKAdenylate cyclase type 5/0.445
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.445
1fvpFMANon-fluorescent flavoprotein/0.445
1gilGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.445
1h74ADPHomoserine kinase2.7.1.390.445
1mgoNADAlcohol dehydrogenase E chain1.1.1.10.445
1qaxHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.445
1rbyGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.445
1v0cACOAAC(6')-Ib/0.445
1vp6CMPCyclic nucleotide-gated potassium channel mll3241/0.445
2bjfDXCCholoylglycine hydrolase3.5.1.240.445
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.445
2g9uG27Glycogen phosphorylase, muscle form2.4.1.10.445
2hw1ANPKetohexokinase/0.445
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.445
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.445
2q7vFADThioredoxin reductase/0.445
2rc3NADCBS domain/0.445
2w2lNADD-mandelate dehydrogenase/0.445
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.445
3bmoNAPPteridine reductase/0.445
3bv3P39Mitogen-activated protein kinase 14/0.445
3ea4FABAcetolactate synthase, chloroplastic2.2.1.60.445
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
3ix8TX3Transcriptional activator protein LasR/0.445
3owaFADAcyl-CoA dehydrogenase/0.445
3oxv478Gag-Pol polyprotein3.4.23.160.445
3p82FMNPentaerythritol tetranitrate reductase/0.445
3pfdFDAAcyl-CoA dehydrogenase FadE25/0.445
3pqbVGPPutative oxidoreductase/0.445
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.445
3t113T1Gag-Pol polyprotein3.4.23.160.445
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
3x2eNAIAdenosylhomocysteinase/0.445
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4bfxZVXPantothenate kinase2.7.1.330.445
4bwxAGSPAB-dependent poly(A)-specific ribonuclease subunit pan3/0.445
4gavFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.445
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.445
4iv6FDAIsovaleryl-CoA dehydrogenase/0.445
4j31FADKynurenine 3-monooxygenase/0.445
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.445
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.445
4mlp2CXCryptochrome-2/0.445
4nzoANPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.445
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.445
4wq4ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.445
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.445
5a3cNADSIR2 family protein/0.445
5bylGCPBifunctional AAC/APH2.3.10.445
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.445
1b8vNADMalate dehydrogenase/0.444
1cg1IMOAdenylosuccinate synthetase/0.444
1d4jMSCGag-Pol polyprotein3.4.23.160.444
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1heuNADAlcohol dehydrogenase E chain1.1.1.10.444
1hldNADAlcohol dehydrogenase E chain1.1.1.10.444
1i2cUPGUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.444
1j39UPGDNA beta-glucosyltransferase/0.444
1k6pXN3Gag-Pol polyprotein3.4.23.160.444
1lbcCYZGlutamate receptor 2/0.444
1levCLIFructose-1,6-bisphosphatase 13.1.3.110.444
1mjaCOAHistone acetyltransferase ESA1/0.444
1naiNADUDP-glucose 4-epimerase5.1.3.20.444
1o94ADPTrimethylamine dehydrogenase1.5.8.20.444
1ol6ATPAurora kinase A2.7.11.10.444
1qorNDPQuinone oxidoreductase 1/0.444
1rdt570Peroxisome proliferator-activated receptor gamma/0.444
1tkgSSAThreonine--tRNA ligase6.1.1.30.444
1trgCB3Thymidylate synthase/0.444
1ve3SAMUncharacterized protein/0.444
2baqPQBMitogen-activated protein kinase 14/0.444
2cgpCMPcAMP-activated global transcriptional regulator CRP/0.444
2eerNADNAD-dependent alcohol dehydrogenase1.1.1.10.444
2fdpFRPBeta-secretase 13.4.23.460.444
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.444
2gcqDOIAdenylosuccinate synthetase/0.444
2hmvADPKtr system potassium uptake protein A/0.444
2ohjFMNType A flavoprotein FprA10.444
2pwcG3GGag-Pol polyprotein3.4.23.160.444
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.444
3f3sNADLambda-crystallin homolog/0.444
3imgBZ3Pantothenate synthetase6.3.2.10.444
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.444
3kboNDPGlyoxylate/hydroxypyruvate reductase A/0.444
3oqkS52Renin3.4.23.150.444
3vruYS3Vitamin D3 receptor/0.444
3wv9FEGHmd co-occurring protein HcgE/0.444
3zptM8YGag-Pol polyprotein3.4.23.160.444
3zuyTCHTransporter/0.444
4dlbNADS-(hydroxymethyl)glutathione dehydrogenase/0.444
4du82P0Mevalonate diphosphate decarboxylase/0.444
4dxd9PCCell division protein FtsZ/0.444
4h4uFADBiphenyl dioxygenase ferredoxin reductase subunit/0.444
4hsuFADLysine-specific histone demethylase 1B10.444
4jq9FADDihydrolipoyl dehydrogenase/0.444
4opgFDAConserved Archaeal protein/0.444
4xyeNADFormate dehydrogenase/0.444
4z875GPInosine-5'-monophosphate dehydrogenase/0.444
1g8jMGDArsenite oxidase subunit AioA1.20.9.10.443
1icuFMNOxygen-insensitive NAD(P)H nitroreductase/0.443
1jgtAPCCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.443
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1ma0NADAlcohol dehydrogenase class-31.1.1.10.443
1ng3FADGlycine oxidase1.4.3.190.443
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.443
1reoFADL-amino-acid oxidase1.4.3.20.443
1rj9GCPSignal recognition particle receptor FtsY/0.443
1uayADNOxidoreductase/0.443
1wzeNADMalate dehydrogenase/0.443
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.443
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.443
2iko7IGRenin3.4.23.150.443
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2oorNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.443
2q2qNADBeta-D-hydroxybutyrate dehydrogenase/0.443
2w0hFADTrypanothione reductase/0.443
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.443
2zb3NDPProstaglandin reductase 21.3.1.480.443
3bazNAPHydroxyphenylpyruvate reductase1.1.1.2370.443
3bbrBHYGlutamate receptor 2/0.443
3fvlBHKCarboxypeptidase A13.4.17.10.443
3gfyFMNUncharacterized protein/0.443
3gw9VNILanosterol 14-alpha-demethylase/0.443
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.443
3pm9FADPutative oxidoreductase/0.443
3qvsNADMyo-inositol-1-phosphate synthase (Ino1)/0.443
3rpeFADPutative modulator of drug activity/0.443
3rypCMPcAMP-activated global transcriptional regulator CRP/0.443
3zhzFM71-deoxy-D-xylulose 5-phosphate reductoisomerase/0.443
4b1uLABActin, alpha skeletal muscle/0.443
4d86ADPPoly [ADP-ribose] polymerase 142.4.2.300.443
4i0bCMPcAMP-activated global transcriptional regulator CRP/0.443
4i22IREEpidermal growth factor receptor2.7.10.10.443
4kip1R9Mitogen-activated protein kinase 14/0.443
4lj7MNTChaperone protein ClpB/0.443
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.443
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.443
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.443
4qi5FADCellobiose dehydrogenase/0.443
4y8wSTRSteroid 21-hydroxylase/0.443
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.443
5jtbZMAAdenosine receptor A2a/0.443
1bdlIM1Gag-Pol polyprotein3.4.23.160.442
1c6yMK1Protease/0.442
1dejATPMajor actin/0.442
1g6nCMPcAMP-activated global transcriptional regulator CRP/0.442
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1ht0NADAlcohol dehydrogenase 1C1.1.1.10.442
1i5zCMPcAMP-activated global transcriptional regulator CRP/0.442
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1kt6RTLRetinol-binding protein 4/0.442
1m75NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.442
1m78NDPDihydrofolate reductase1.5.1.30.442
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.442
1onfFADGlutathione reductase1.8.1.70.442
1oriSAHProtein arginine N-methyltransferase 1/0.442
1qinGIPLactoylglutathione lyase4.4.1.50.442
1rbzKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.442
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.442
2aa0MTPAdenosine kinase2.7.1.200.442
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2d29FADAcyl-CoA dehydrogenase/0.442
2daaDCSD-alanine aminotransferase2.6.1.210.442
2gf6COAUncharacterized protein/0.442
2q3fGNPRas-related GTP-binding protein D/0.442
2qenADPWalker-Type ATPase/0.442
2qo9ANPEphrin type-A receptor 32.7.10.10.442
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
2vceU2FUDP-glycosyltransferase 72B1/0.442
2vhxNADAlanine dehydrogenase1.4.1.10.442
2xlrFADPutative flavin-containing monooxygenase/0.442
3biz61EWee1-like protein kinase2.7.10.20.442
3cluFADElectron transfer flavoprotein subunit alpha/0.442
3d84NDPDihydrofolate reductase1.5.1.30.442
3e9yFABAcetolactate synthase, chloroplastic2.2.1.60.442
3fln3FNMitogen-activated protein kinase 14/0.442
3fwjCAMCamphor 5-monooxygenase1.14.15.10.442
3ge1ADPGlycerol kinase/0.442
3l0lHC3Nuclear receptor ROR-gamma/0.442
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.442
3nbvANPKetohexokinase/0.442
3ocgOCGMitogen-activated protein kinase 14/0.442
3qcx3Q23-phosphoinositide-dependent protein kinase 12.7.11.10.442
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.442
3qihNI7Gag-Pol polyprotein3.4.23.160.442
3t2vKKJPeptidoglycan recognition protein 1/0.442
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.442
4a61ANPPlasmid segregation protein ParM/0.442
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.442
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.442
4gs4ACOAlpha-tubulin N-acetyltransferase 1/0.442
4h1m0YJProtein-tyrosine kinase 2-beta2.7.10.20.442
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.442
4ig01FGGag-Pol polyprotein2.7.7.490.442
4jx1CAMCamphor 5-monooxygenase1.14.15.10.442
4k42ADPActin, alpha skeletal muscle/0.442
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.442
4r38RBFBlue-light-activated histidine kinase 22.7.13.30.442
4riyADPEpidermal growth factor receptor2.7.10.10.442
4rpgFADUDP-galactopyranose mutase5.4.99.90.442
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
5bukFADFADH2-dependent halogenase/0.442
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.442
5cdgNAJAlcohol dehydrogenase E chain1.1.1.10.442
5eccNAPDehydrofolate reductase type I/0.442
5fs8FADApoptosis-inducing factor 1, mitochondrial1.1.10.442
5iqhGNPBifunctional AAC/APH2.3.10.442
1adfTADAlcohol dehydrogenase E chain1.1.1.10.441
1aj8COACitrate synthase/0.441
1bl6SB6Mitogen-activated protein kinase 14/0.441
1cgpCMPcAMP-activated global transcriptional regulator CRP/0.441
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1h48CDI2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.441
1i2lDCSAminodeoxychorismate lyase4.1.3.380.441
1ia1NDPDihydrofolate reductase1.5.1.30.441
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.441
1qnfHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.441
1qy5NECEndoplasmin/0.441
1rm5NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.441
1rwbNADGlucose 1-dehydrogenase1.1.1.470.441
1z7yAA5Cysteine synthase 12.5.1.470.441
1zhwHC2Oxysterol-binding protein homolog 4/0.441
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.441
2c0iL1GTyrosine-protein kinase HCK2.7.10.20.441
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.441
2dfvNADL-threonine 3-dehydrogenase/0.441
2dvlFADAcyl-CoA dehydrogenase/0.441
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.441
2ittAEEEpidermal growth factor receptor2.7.10.10.441
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.441
2pv7NADT-protein1.3.1.120.441
2qi0MZ3Gag-Pol polyprotein/0.441
2rhgIGPTryptophan synthase alpha chain/0.441
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.441
3b895GP16S rRNA methylase/0.441
3cs8BRLPeroxisome proliferator-activated receptor gamma/0.441
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.441
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3kgcLY7Glutamate receptor 2/0.441
3m9vTYDFAD-dependent oxidoreductase/0.441
3nbwTR4Ketohexokinase/0.441
3ol5SAWCamphor 5-monooxygenase1.14.15.10.441
3s1sSAHRestriction endonuclease BpuSI/0.441
3s5wFADL-ornithine N(5)-monooxygenase/0.441
3tneRITCandidapepsin-13.4.23.240.441
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.441
3up4FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.441
3vryB43Tyrosine-protein kinase HCK2.7.10.20.441
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.441
4aa4QC0Mitogen-activated protein kinase 14/0.441
4b68NAPL-ornithine N(5)-monooxygenase/0.441
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.441
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4e8wIHAD-beta-D-heptose 7-phosphate kinase/0.441
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.441
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.441
4ia3BIVVitamin D3 receptor A/0.441
4ipw1G7Mycocyclosin synthase1.14.21.90.441
4kiq1RAMitogen-activated protein kinase 14/0.441
4n6hEJ4Delta-type opioid receptor/0.441
4rlsNAIL-lactate dehydrogenase A chain1.1.1.270.441
4uunNAIL-lactate dehydrogenase/0.441
4y9qC2EUncharacterized protein/0.441
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.441
5kj1NAJAlcohol dehydrogenase E chain1.1.1.10.441
1bwlFMNNADPH dehydrogenase 11.6.99.10.440
1bxqPP8Penicillopepsin-13.4.23.200.440
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1nlmUD1UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase/0.440
1rc4DDFDihydrofolate reductase1.5.1.30.440
1scuCOASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.440
1u28NADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.440
1vdcFADThioredoxin reductase 1, mitochondrial1.8.1.90.440
1xkkFMMEpidermal growth factor receptor2.7.10.10.440
1zgdNAPChalcone reductase/0.440
1zhzERGOxysterol-binding protein homolog 4/0.440
1zrzBI1Protein kinase C iota type2.7.11.130.440
2a94AP0L-lactate dehydrogenase1.1.1.270.440
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2gr1FADFerredoxin reductase/0.440
2itnANPEpidermal growth factor receptor2.7.10.10.440
2j3iNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.440
2j9gANPBiotin carboxylase6.3.4.140.440
2pwrG4GGag-Pol polyprotein3.4.23.160.440
2qnqQN3Gag-Pol polyprotein3.4.23.160.440
2tmdADPTrimethylamine dehydrogenase1.5.8.20.440
2uzfCAA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.440
2vhwNAIAlanine dehydrogenase1.4.1.10.440
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.440
2webPP4Penicillopepsin-13.4.23.200.440
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.440
2xneASHAurora kinase A2.7.11.10.440
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.440
2ywlFADThioredoxin reductase related protein/0.440
3bgcLJHGag-Pol polyprotein3.4.23.160.440
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.440
3el2ATPActin-5C/0.440
3fwrADPTranscriptional repressor CcpN/0.440
3ggpNADPrephenate dehydrogenase/0.440
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.440
3k4vROCGag-Pol polyprotein3.4.23.160.440
3lzv017Gag-Pol polyprotein3.4.23.160.440
3ozsOZSCatechol O-methyltransferase2.1.1.60.440
3ql6NIMLactoperoxidase1.11.1.70.440
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.440
3sjhLARActin, alpha skeletal muscle/0.440
3vjoANPEpidermal growth factor receptor2.7.10.10.440
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.440
4abkAR6Poly [ADP-ribose] polymerase 142.4.2.300.440
4b8wNAPGDP-L-fucose synthase1.1.1.2710.440
4cj4S3GIntegrase/0.440
4el0D1KGlycogen phosphorylase, muscle form2.4.1.10.440
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.440
4g2fC07Ephrin type-A receptor 32.7.10.10.440
4jc51K5Stimulator of interferon genes protein/0.440
4px9ADPATP-dependent RNA helicase DDX3X3.6.4.130.440
5c3zACPRibokinase/0.440
5cvfATPCasein kinase II subunit alpha2.7.11.10.440
5cx6CDPRNA-dependent RNA polymerase/0.440