sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2j2p | SC2 | Ficolin-2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2j2p | SC2 | Ficolin-2 | / | 1.000 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.477 | |
| 2vwp | NDP | Glucose 1-dehydrogenase | / | 0.477 | |
| 5aga | ANP | DNA polymerase theta | / | 0.477 | |
| 4cw5 | FMN | DfnA | / | 0.471 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.463 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.459 | |
| 4e07 | ACP | Plasmid partitioning protein ParF | / | 0.458 | |
| 4z38 | FMN | MlnA | / | 0.458 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.457 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.456 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.456 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.456 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.455 | |
| 4y95 | 746 | Tyrosine-protein kinase | / | 0.452 | |
| 5cyp | GSP | Septin-9 | / | 0.452 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.451 | |
| 1u33 | LM2 | Pancreatic alpha-amylase | / | 0.449 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.449 | |
| 4yus | FMN | Family 3 adenylate cyclase | / | 0.448 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.447 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.447 | |
| 3zxs | FAD | Deoxyribodipyrimidine photolyase-related protein | / | 0.447 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.446 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4yqf | GDP | Septin-9 | / | 0.446 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.445 | |
| 4qxr | 1YE | Stimulator of interferon genes protein | / | 0.445 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.444 | |
| 1p4a | PCP | Pur operon repressor | / | 0.444 | |
| 1j21 | ATP | Argininosuccinate synthase | / | 0.443 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.443 | |
| 3h03 | UBP | Glutamate receptor 2 | / | 0.443 | |
| 1ayl | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.442 | |
| 3n8n | N88 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.442 | |
| 3qtt | ANP | Pantothenate synthetase | / | 0.442 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.442 | |
| 5cwa | 0GA | Anthranilate synthase component 1 | 4.1.3.27 | 0.442 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.441 | |
| 2xka | GSP | Cell division protein FtsZ | / | 0.441 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.441 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.441 | |
| 3pls | ANP | Macrophage-stimulating protein receptor | 2.7.10.1 | 0.441 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.441 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.441 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.441 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.440 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.440 | |
| 1kp8 | AGS | 60 kDa chaperonin | / | 0.440 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.440 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.440 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.440 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.440 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.440 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.440 |