sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2izg | BTN | Streptavidin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2izg | BTN | Streptavidin | / | 1.000 | |
| 2rtf | BTN | Streptavidin | / | 0.808 | |
| 2izf | BTN | Streptavidin | / | 0.798 | |
| 2izl | IMI | Streptavidin | / | 0.796 | |
| 2rtg | BTN | Streptavidin | / | 0.792 | |
| 2rtd | BTN | Streptavidin | / | 0.786 | |
| 2izh | BTN | Streptavidin | / | 0.768 | |
| 2rte | BTN | Streptavidin | / | 0.760 | |
| 2rtp | IMI | Streptavidin | / | 0.742 | |
| 2rto | IMI | Streptavidin | / | 0.700 | |
| 2rtq | IMI | Streptavidin | / | 0.686 | |
| 1sre | HAB | Streptavidin | / | 0.675 | |
| 2rtn | IMI | Streptavidin | / | 0.668 | |
| 1mk5 | BTN | Streptavidin | / | 0.667 | |
| 3wzn | BTN | Streptavidin | / | 0.667 | |
| 1lcw | SHM | Streptavidin | / | 0.662 | |
| 4gda | BTN | Streptavidin | / | 0.656 | |
| 4dne | DTB | Streptavidin | / | 0.655 | |
| 3ry2 | BTN | Streptavidin | / | 0.653 | |
| 1stp | BTN | Streptavidin | / | 0.648 | |
| 2rti | GLL | Streptavidin | / | 0.648 | |
| 4bx7 | B4F | Streptavidin | / | 0.647 | |
| 1srh | MOB | Streptavidin | / | 0.645 | |
| 1i9h | BNI | Streptavidin | / | 0.636 | |
| 3wyq | BTN | Streptavidin | / | 0.636 | |
| 1srf | MTB | Streptavidin | / | 0.633 | |
| 1sri | DMB | Streptavidin | / | 0.633 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.633 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.631 | |
| 2rtr | IMI | Streptavidin | / | 0.630 | |
| 1swt | BTN | Streptavidin | / | 0.629 | |
| 1df8 | BTN | Streptavidin | / | 0.624 | |
| 2y3f | BTN | Streptavidin | / | 0.620 | |
| 1srg | MHB | Streptavidin | / | 0.618 | |
| 2c4i | BTN | Avidin | / | 0.612 | |
| 1lcz | BH7 | Streptavidin | / | 0.610 | |
| 1srj | NAB | Streptavidin | / | 0.605 | |
| 1luq | BTN | Streptavidin | / | 0.603 | |
| 1rxh | BNI | Streptavidin | / | 0.603 | |
| 2izj | BTN | Streptavidin | / | 0.590 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.587 | |
| 3ew2 | BTN | Hypothetical conserved protein | / | 0.584 | |
| 1swp | BTQ | Streptavidin | / | 0.582 | |
| 2izi | BTN | Streptavidin | / | 0.582 | |
| 1avd | BTN | Avidin | / | 0.580 | |
| 1nqm | BTN | Streptavidin | / | 0.578 | |
| 2avi | BTN | Avidin | / | 0.578 | |
| 2uz2 | BTN | Avd protein | / | 0.576 | |
| 4yvb | BTN | Streptavidin | / | 0.574 | |
| 2rtm | IMI | Streptavidin | / | 0.573 | |
| 4z28 | BTN | Hoefavidin | / | 0.562 | |
| 1swp | BTN | Streptavidin | / | 0.558 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.558 | |
| 3rdq | DTB | Streptavidin | / | 0.554 | |
| 2uyw | BTN | Avd protein | / | 0.550 | |
| 3t2w | BTN | Avidin/streptavidin | / | 0.549 | |
| 2rtk | GLL | Streptavidin | / | 0.546 | |
| 1swe | BTN | Streptavidin | / | 0.540 | |
| 1nc9 | IMI | Streptavidin | / | 0.539 | |
| 1swr | BTN | Streptavidin | / | 0.538 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.536 | |
| 1n43 | BTN | Streptavidin | / | 0.531 | |
| 2izk | GLL | Streptavidin | / | 0.531 | |
| 1mep | BTN | Streptavidin | / | 0.524 | |
| 1n9m | BTN | Streptavidin | / | 0.524 | |
| 2zsc | BTN | Tamavidin2 | / | 0.524 | |
| 1ndj | BTN | Streptavidin | / | 0.523 | |
| 1swn | BTN | Streptavidin | / | 0.523 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.521 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.514 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.513 | |
| 1axw | MTX | Thymidylate synthase | / | 0.512 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.512 | |
| 2a5c | 8DA | Avidin | / | 0.511 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.510 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.504 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.502 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.500 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.500 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.500 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.499 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.499 | |
| 1nw6 | SFG | Modification methylase RsrI | 2.1.1.72 | 0.497 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.497 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.496 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.495 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.494 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.494 | |
| 2jgs | BTN | Avidin | / | 0.493 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.492 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.492 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.491 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.491 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.490 | |
| 2kce | D16 | Thymidylate synthase | / | 0.490 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.490 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.490 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.489 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.488 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.488 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.487 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.487 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.487 | |
| 3up0 | D7S | aceDAF-12 | / | 0.487 | |
| 3wyp | BSO | Streptavidin | / | 0.487 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.486 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.485 | |
| 4bj8 | BTN | Avidin | / | 0.485 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.485 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.485 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.484 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.483 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.482 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.482 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.482 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.482 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.481 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.480 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.480 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.479 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.478 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.478 | |
| 4rtm | SAM | DNA adenine methylase | 2.1.1.72 | 0.478 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.478 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.477 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.477 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.477 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.477 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.477 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.477 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.477 | |
| 4xd1 | T3Q | Qdtf | / | 0.477 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.476 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.476 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.475 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.475 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.475 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.475 | |
| 3wff | WFF | Mineralocorticoid receptor | / | 0.475 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.474 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.474 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.474 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.474 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.474 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.474 | |
| 4rtl | SFG | DNA adenine methylase | 2.1.1.72 | 0.474 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.473 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.473 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.473 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.473 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.473 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.473 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.473 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.473 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.473 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.473 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.472 | |
| 1kzi | THG | Thymidylate synthase | / | 0.472 | |
| 2rtl | IMI | Streptavidin | / | 0.472 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.472 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.472 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.472 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.472 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.472 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.472 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.472 | |
| 3pz2 | 3PZ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.472 | |
| 3qly | 55V | Uncharacterized protein | / | 0.472 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.472 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.472 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.472 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.472 | |
| 1lke | DOG | Bilin-binding protein | / | 0.471 | |
| 1osv | CHC | Bile acid receptor | / | 0.471 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.471 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.471 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.471 | |
| 3owu | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.471 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.471 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.471 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.471 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.470 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.470 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.470 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.470 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.470 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.470 | |
| 1afs | TES | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.469 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.469 | |
| 2ilu | NDP | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.469 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.469 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.469 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.469 | |
| 3f0r | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.469 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.469 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.469 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.468 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2hvd | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.468 | |
| 2v1a | FMN | NPH1-1 | / | 0.468 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.468 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.468 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.468 | |
| 4gd9 | BTN | Streptavidin | / | 0.468 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.468 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.468 | |
| 4ydd | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.468 | |
| 5egh | PC | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 | / | 0.468 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.467 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.467 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.467 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.467 | |
| 2h6i | CYS_VAL_LEU_SER_GER | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.467 | |
| 2wet | FAD | Tryptophan 5-halogenase | / | 0.467 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.467 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.467 | |
| 3i1y | 33N | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.467 | |
| 3vgw | NVZ | Avidin | / | 0.467 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.467 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.467 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.467 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.466 | |
| 1tsx | UMP | Thymidylate synthase | / | 0.466 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 3r0t | FU9 | Casein kinase II subunit alpha | 2.7.11.1 | 0.466 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.466 | |
| 4c1f | X8Z | Metallo-beta-lactamase type 2 | / | 0.466 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.466 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.465 | |
| 1c7o | PPG | Hemolysin | / | 0.465 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.465 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.465 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.465 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.465 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.465 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.465 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.464 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.464 | |
| 4avl | TMP | Polymerase acidic protein | / | 0.464 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.464 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.463 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.463 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.463 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.463 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.463 | |
| 3arv | SAU | Chitinase A | / | 0.463 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.463 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.463 | |
| 3q5p | TAC | Multidrug-efflux transporter 1 regulator | / | 0.463 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.463 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.463 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.463 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.463 | |
| 1eg2 | MTA | Modification methylase RsrI | 2.1.1.72 | 0.462 | |
| 1rx4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.462 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.462 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.462 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 3ceh | AVE | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.462 | |
| 3hav | ATP | Aminoglycoside phosphotransferase | / | 0.462 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.462 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.462 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.462 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.462 | |
| 4mry | CEI | Obelin | / | 0.462 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.462 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.462 | |
| 5k0s | 0OU | Methionine--tRNA ligase | / | 0.462 | |
| 1buc | FAD | Acyl-CoA dehydrogenase, short-chain specific | 1.3.8.1 | 0.461 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.461 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.461 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.461 | |
| 1s9d | AFB | Cytohesin-2 | / | 0.461 | |
| 1s9d | AFB | ADP-ribosylation factor 1 | / | 0.461 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.461 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.461 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 2dy9 | ADP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.461 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.461 | |
| 2npf | MOU | Elongation factor 2 | / | 0.461 | |
| 2xej | OKD | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.461 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.461 | |
| 4h0v | NAD | Iota toxin component Ia | / | 0.461 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.461 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.461 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.461 | |
| 1ddt | APU | Diphtheria toxin | / | 0.460 | |
| 1kt7 | RTL | Retinol-binding protein 4 | / | 0.460 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.460 | |
| 1zdw | FLV | Prenyltransferase | / | 0.460 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.460 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.460 | |
| 3ehj | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.460 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.460 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.460 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.460 | |
| 1ao8 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.459 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 1n0u | SO1 | Elongation factor 2 | / | 0.459 | |
| 1t7r | DHT | Androgen receptor | / | 0.459 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.459 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.459 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.459 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.459 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.459 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.459 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.459 | |
| 4uga | Q05 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.459 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.459 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.458 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.458 | |
| 1kph | SAH | Cyclopropane mycolic acid synthase 1 | 2.1.1.79 | 0.458 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 1tys | DHF | Thymidylate synthase | / | 0.458 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.458 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.458 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.458 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.458 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.458 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.458 | |
| 3dqr | JI2 | Nitric oxide synthase, brain | 1.14.13.39 | 0.458 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.458 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.458 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.458 | |
| 3owy | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.458 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.458 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.458 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.458 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.457 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.457 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.457 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.457 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.457 | |
| 3mb6 | 01I | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.457 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.457 | |
| 3wfg | WFG | Mineralocorticoid receptor | / | 0.457 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.457 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.457 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.457 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.456 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.456 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 2f0y | 3MN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.456 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.456 | |
| 3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.456 | |
| 4rto | SFG | DNA adenine methylase | 2.1.1.72 | 0.456 | |
| 4rtq | SAH | DNA adenine methylase | 2.1.1.72 | 0.456 | |
| 4uyg | 73B | Bromodomain-containing protein 2 | / | 0.456 | |
| 4xcz | T3Q | Qdtf | / | 0.456 | |
| 5iqg | GDP | Bifunctional AAC/APH | 2.3.1 | 0.456 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.456 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1m67 | BOA | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.455 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.455 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.455 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.455 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.455 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 3rv3 | ADP | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.455 | |
| 4ggz | BTN | Bll1558 protein | / | 0.455 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.455 | |
| 4rtj | SFG | DNA adenine methylase | 2.1.1.72 | 0.455 | |
| 4rtk | SAH | DNA adenine methylase | 2.1.1.72 | 0.455 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.455 | |
| 4uof | DAT | Nucleoside diphosphate kinase | / | 0.455 | |
| 1e2n | RCA | Thymidine kinase | / | 0.454 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.454 | |
| 1mzs | 669 | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.454 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.454 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.454 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.454 | |
| 1yw1 | FMN | Putative monooxygenase MoxC | 1.14 | 0.454 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.454 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.454 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.454 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.454 | |
| 2ow9 | SP6 | Collagenase 3 | 3.4.24 | 0.454 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.454 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.454 | |
| 4kxj | P34 | Nucleoprotein | / | 0.454 | |
| 4nhk | PD2 | Prolyl 3,4-dihydroxylase TPA1 | 1.14.11 | 0.454 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.454 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.454 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.453 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.453 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.453 | |
| 2j6x | FMN | Lactate oxidase | / | 0.453 | |
| 2mok | FMN | Flavodoxin 1 | / | 0.453 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 2wu5 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.453 | |
| 2wu5 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.453 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.453 | |
| 3c6t | M14 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.453 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.453 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 3n8y | DIF | Prostaglandin G/H synthase 1 | 1.14.99.1 | 0.453 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 4aos | FAD | Steroid monooxygenase | / | 0.453 | |
| 4e5h | 0N8 | Polymerase acidic protein | / | 0.453 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.453 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.453 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.453 | |
| 5iqb | GNP | Bifunctional AAC/APH | 2.3.1 | 0.453 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.453 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.452 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.452 | |
| 1l8a | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.452 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
| 1t79 | DHT | Androgen receptor | / | 0.452 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 2p9e | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.452 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.452 | |
| 2uup | LK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.452 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.452 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.452 | |
| 2ylo | TES | Androgen receptor | / | 0.452 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.452 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.452 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.452 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.452 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.452 | |
| 4hlf | 15Z | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.452 | |
| 4u7w | NDP | MxaA | / | 0.452 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.451 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.451 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 1nc1 | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.451 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.451 | |
| 1t7t | DHT | Androgen receptor | / | 0.451 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.451 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 2fg5 | GNP | Ras-related protein Rab-31 | / | 0.451 | |
| 2qvd | BER | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.451 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.451 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.451 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.451 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4dli | IRG | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.451 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.451 | |
| 4v26 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.451 | |
| 4ys2 | 2BA | Uncharacterized protein | / | 0.451 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.451 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.451 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.450 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.450 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.450 | |
| 1xp8 | AGS | Protein RecA | / | 0.450 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.450 | |
| 2iej | S48 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.450 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.450 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.450 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.450 | |
| 2x93 | X93 | Angiotensin-converting enzyme | 3.4.15.1 | 0.450 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.450 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.450 | |
| 3hxb | BD5 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.450 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.450 | |
| 3v49 | PK0 | Androgen receptor | / | 0.450 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.450 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 4hmb | PZZ | Phospholipase A2 VRV-PL-VIIIa | / | 0.450 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.450 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.450 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.450 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.450 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.449 | |
| 1mdt | APU | Diphtheria toxin | / | 0.449 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.449 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.449 | |
| 1s7n | COA | Acetyl transferase | / | 0.449 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2od7 | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.449 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.449 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.449 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.449 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 3gg2 | UGA | Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family | / | 0.449 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.449 | |
| 3otq | MZL | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.449 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.449 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.449 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.449 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.449 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.449 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4i4b | 1CV | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.449 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.449 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.449 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.449 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.448 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.448 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.448 | |
| 1tw2 | ERT | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.448 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.448 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.448 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.448 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.448 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.448 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.448 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.448 | |
| 2qpy | DHT | Androgen receptor | / | 0.448 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3pe1 | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.448 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4bvb | OCZ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.448 | |
| 4bvh | OCZ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.448 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.448 | |
| 4kko | 1RE | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.448 | |
| 4rts | SAM | DNA adenine methylase | 2.1.1.72 | 0.448 | |
| 5f2k | SAH | Uncharacterized protein | / | 0.448 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.448 | |
| 5k0t | 415 | Methionine--tRNA ligase | / | 0.448 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.448 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.447 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1e7a | PFL | Serum albumin | / | 0.447 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.447 | |
| 1mzc | BNE | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 1nen | DNT | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.447 | |
| 1nen | DNT | Succinate dehydrogenase cytochrome b556 subunit | / | 0.447 | |
| 1nja | DCM | Thymidylate synthase | / | 0.447 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.447 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.447 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.447 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.447 | |
| 2f4j | VX6 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.447 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.447 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.447 | |
| 2rgb | GNP | GTPase HRas | / | 0.447 | |
| 3bhr | THG | Thymidylate synthase | / | 0.447 | |
| 3eks | CY9 | Actin-5C | / | 0.447 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.447 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.447 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.447 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.447 | |
| 3qfr | FAD | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 3tfq | 07M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 4bqu | CLR | Japanin | / | 0.447 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.447 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.447 | |
| 4fgr | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 6.3.2.6 | 0.447 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.447 | |
| 4kwh | NAP | Reductase homolog | / | 0.447 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.447 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.447 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.447 | |
| 4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.447 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.447 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.447 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.446 | |
| 1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.446 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.446 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.446 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2ofv | 242 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.446 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.446 | |
| 2rht | C1E | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.446 | |
| 2wu2 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.446 | |
| 2wu2 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.446 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.446 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.446 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.446 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.446 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.446 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.446 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.446 | |
| 3uud | EST | Estrogen receptor | / | 0.446 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.446 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.446 | |
| 4die | C5P | Cytidylate kinase | / | 0.446 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.446 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.446 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.446 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.446 | |
| 5iqe | GNP | Bifunctional AAC/APH | 2.3.1 | 0.446 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.445 | |
| 1fml | RTL | Retinol dehydratase | / | 0.445 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.445 | |
| 1ldq | SHM | Avidin | / | 0.445 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.445 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.445 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.445 | |
| 2dxf | GNP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.445 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.445 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.445 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.445 | |
| 2tsr | UMP | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 2y67 | N21 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.445 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.445 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.445 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.445 | |
| 3dej | RXC | Caspase-3 | 3.4.22.56 | 0.445 | |
| 3g8d | ADP | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 3gts | D3M | DdmC | / | 0.445 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.445 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3pd5 | TSB | Threonine--tRNA ligase | 6.1.1.3 | 0.445 | |
| 3qcj | NX4 | Receptor-type tyrosine-protein phosphatase gamma | 3.1.3.48 | 0.445 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.445 | |
| 4avg | SL6 | Polymerase acidic protein | / | 0.445 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.445 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.445 | |
| 4hdr | DMD | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | / | 0.445 | |
| 4hdr | DMD | ArsB | / | 0.445 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.445 | |
| 4ivr | N50 | Thymidine kinase | / | 0.445 | |
| 4k7a | DHT | Androgen receptor | / | 0.445 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.445 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 4ofu | DHT | Androgen receptor | / | 0.445 | |
| 4uoh | ADP | Nucleoside diphosphate kinase | / | 0.445 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.445 | |
| 4z9r | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.445 | |
| 5a3b | APR | SIR2 family protein | / | 0.445 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1efa | NPF | Lactose operon repressor | / | 0.444 | |
| 1err | RAL | Estrogen receptor | / | 0.444 | |
| 1f28 | F89 | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.444 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1ndy | FR3 | Adenosine deaminase | 3.5.4.4 | 0.444 | |
| 1s1v | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 1uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2amb | 17H | Androgen receptor | / | 0.444 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.444 | |
| 2jfa | RAL | Estrogen receptor | / | 0.444 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.444 | |
| 2vdy | HCY | Corticosteroid-binding globulin | / | 0.444 | |
| 2vo4 | GTB | 2,4-D inducible glutathione S-transferase | / | 0.444 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.444 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.444 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3e6o | A55 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.444 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.444 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3h1j | SMA | Cytochrome b | / | 0.444 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.444 | |
| 3l5b | BDO | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.444 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.444 | |
| 3p9t | TCL | Repressor | / | 0.444 | |
| 3qgd | 26S | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3qzy | FAD | FAD-linked sulfhydryl oxidase | / | 0.444 | |
| 3rim | TPP | Transketolase | 2.2.1.1 | 0.444 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4ere | 0R2 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.444 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.444 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4jhi | EMU | Nodulin-13 | / | 0.444 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.444 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.444 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.444 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.444 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.444 | |
| 5cpm | FNR | NADH:flavin oxidoreductase | / | 0.444 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.443 | |
| 1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.443 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.443 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.443 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.443 | |
| 2dpm | SAM | Modification methylase DpnIIA | 2.1.1.72 | 0.443 | |
| 2ore | SAH | DNA adenine methylase | 2.1.1.72 | 0.443 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2wdq | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.443 | |
| 2wdq | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.443 | |
| 2wgg | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.443 | |
| 2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.443 | |
| 2xvv | 9DN | Serum albumin | / | 0.443 | |
| 2yhu | WHF | Pteridine reductase | / | 0.443 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.443 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 3cse | N22 | Uncharacterized protein | / | 0.443 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 3glu | LYS_VAL_MET | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.443 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.443 | |
| 3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3lu8 | IQX | Serum albumin | / | 0.443 | |
| 3mnp | DEX | Glucocorticoid receptor | / | 0.443 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.443 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.443 | |
| 3tif | ADP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.443 | |
| 3tpt | ADP | Serine/threonine-protein kinase toxin HipA | / | 0.443 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.443 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.443 | |
| 4b45 | GSP | Tubulin-like protein CetZ2 | / | 0.443 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.443 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.443 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.443 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.443 | |
| 4kxl | 6C6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.443 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.443 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.443 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.443 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.443 | |
| 5d9j | 0N8 | Polymerase acidic protein | / | 0.443 | |
| 5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.443 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.442 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1jmi | UMP | Thymidylate synthase | / | 0.442 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1po7 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.442 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.442 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.442 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.442 | |
| 2piu | DHT | Androgen receptor | / | 0.442 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.442 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.442 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 2y5s | 78H | Dihydropteroate synthase | / | 0.442 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.442 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.442 | |
| 3anm | SYD | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.442 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3eek | 53S | Uncharacterized protein | / | 0.442 | |
| 3fmw | FAD | Oxygenase | / | 0.442 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.442 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3mte | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.442 | |
| 3p3c | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.442 | |
| 3p9k | CIY | Caffeic acid O-methyltransferase | / | 0.442 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.442 | |
| 3up3 | XCA | aceDAF-12 | / | 0.442 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.442 | |
| 4alx | IZN | Acetylcholine-binding protein | / | 0.442 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.442 | |
| 4ffl | ADP | Uncharacterized protein | / | 0.442 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.442 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.442 | |
| 4nqg | CZH | Mitrocomin | / | 0.442 | |
| 4nt3 | ZAW | Lactoperoxidase | 1.11.1.7 | 0.442 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.442 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.441 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1i75 | NOJ | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.441 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.441 | |
| 1re0 | AFB | ADP-ribosylation factor 1 | / | 0.441 | |
| 1re0 | AFB | ARF guanine-nucleotide exchange factor 1 | / | 0.441 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.441 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.441 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.441 | |
| 2g1p | SAH | DNA adenine methylase | 2.1.1.72 | 0.441 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.441 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.441 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.441 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.441 | |
| 2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.441 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.441 | |
| 3b9l | AZZ | Serum albumin | / | 0.441 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.441 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.441 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3n63 | XFN | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.441 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.441 | |
| 4bfp | SWY | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4h6p | FMN | Chromate reductase | / | 0.441 | |
| 4l8u | 9AZ | Serum albumin | / | 0.441 | |
| 4oez | DHT | Androgen receptor | / | 0.441 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.441 | |
| 5fdg | 0N8 | Polymerase acidic protein | / | 0.441 | |
| 5iqh | GNP | Bifunctional AAC/APH | 2.3.1 | 0.441 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.440 | |
| 1bq1 | CB3 | Thymidylate synthase | / | 0.440 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1dtp | APU | Diphtheria toxin | / | 0.440 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.440 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.440 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.440 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.440 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.440 | |
| 1tg2 | H2B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.440 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2aa5 | STR | Mineralocorticoid receptor | / | 0.440 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.440 | |
| 2c3p | 1TP | Pyruvate synthase | / | 0.440 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 2g97 | DGB | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.440 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.440 | |
| 2hsa | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.440 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.440 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.440 | |
| 2pio | DHT | Androgen receptor | / | 0.440 | |
| 2piw | DHT | Androgen receptor | / | 0.440 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.440 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2vro | NDP | 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase | / | 0.440 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.440 | |
| 2y0d | UGA | UDP-glucose dehydrogenase | / | 0.440 | |
| 2zul | SAM | Probable ribosomal RNA small subunit methyltransferase | / | 0.440 | |
| 3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.440 | |
| 3nju | ANN | Acidic phospholipase A2 3 | 3.1.1.4 | 0.440 | |
| 3ol5 | SAW | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3tq8 | TOP | Dihydrofolate reductase | / | 0.440 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.440 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 4eqs | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 4k88 | HFG | Bifunctional glutamate/proline--tRNA ligase | 6.1.1.15 | 0.440 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.440 | |
| 4kq2 | U5P | Glycogen [starch] synthase isoform 2 | 2.4.1.11 | 0.440 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.440 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.440 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.440 |