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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2iskFNR5,6-dimethylbenzimidazole synthase1.13.11.79

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2iskFNR5,6-dimethylbenzimidazole synthase1.13.11.791.000
2islFNR5,6-dimethylbenzimidazole synthase1.13.11.790.655
2isjFMN5,6-dimethylbenzimidazole synthase1.13.11.790.570
3eo8FMNPutative nitroreductase/0.483
4prxADPDNA gyrase subunit B/0.464
3w233RODihydroorotate dehydrogenase (fumarate)1.3.98.10.462
4a5lNDPThioredoxin reductase/0.461
4mlp2CXCryptochrome-2/0.453
3koqFMNPutative nitroreductase/0.448
1iqrFADDeoxyribodipyrimidine photo-lyase4.1.99.30.442
3e39FMNNitroreductase/0.442
4p2lFADSulfhydryl oxidase 11.8.3.20.441
2zevIPEGeranylgeranyl pyrophosphate synthase/0.440