sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ipw | 2CL | Aldose reductase | 1.1.1.21 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2ipw | 2CL | Aldose reductase | 1.1.1.21 | 1.000 | |
| 1az1 | ALR | Aldose reductase | 1.1.1.21 | 0.645 | |
| 2is7 | 2CL | Aldose reductase | 1.1.1.21 | 0.596 | |
| 2pdk | SBI | Aldose reductase | 1.1.1.21 | 0.588 | |
| 2f2k | TGG | Aldose reductase | 1.1.1.21 | 0.567 | |
| 2pd9 | FID | Aldose reductase | 1.1.1.21 | 0.564 | |
| 2pdy | FID | Aldose reductase | 1.1.1.21 | 0.563 | |
| 2nvd | ITB | Aldose reductase | 1.1.1.21 | 0.554 | |
| 3u2c | SUZ | Aldose reductase | 1.1.1.21 | 0.554 | |
| 3v35 | NTI | Aldose reductase | 1.1.1.21 | 0.551 | |
| 1pwm | FID | Aldose reductase | 1.1.1.21 | 0.549 | |
| 3s3g | TLT | Aldose reductase | 1.1.1.21 | 0.548 | |
| 2pdg | 47D | Aldose reductase | 1.1.1.21 | 0.542 | |
| 2pdw | FID | Aldose reductase | 1.1.1.21 | 0.532 | |
| 1us0 | LDT | Aldose reductase | 1.1.1.21 | 0.528 | |
| 3ghs | LDT | Aldose reductase | 1.1.1.21 | 0.528 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.525 | |
| 1eko | I84 | Aldose reductase | 1.1.1.21 | 0.523 | |
| 2fzb | TOL | Aldose reductase | 1.1.1.21 | 0.523 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.521 | |
| 2hvn | ZST | Aldose reductase | 1.1.1.21 | 0.519 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.519 | |
| 2agt | FID | Aldose reductase | 1.1.1.21 | 0.516 | |
| 3h4g | FID | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.516 | |
| 2inz | OHP | Aldose reductase | 1.1.1.21 | 0.515 | |
| 1pwl | BFI | Aldose reductase | 1.1.1.21 | 0.513 | |
| 3ghu | LDT | Aldose reductase | 1.1.1.21 | 0.513 | |
| 3p2v | DOY | Aldose reductase | 1.1.1.21 | 0.511 | |
| 3g5e | Q74 | Aldose reductase | 1.1.1.21 | 0.510 | |
| 1ah0 | SBI | Aldose reductase | 1.1.1.21 | 0.507 | |
| 2i16 | LDT | Aldose reductase | 1.1.1.21 | 0.507 | |
| 2qxw | LDT | Aldose reductase | 1.1.1.21 | 0.507 | |
| 1rxj | BNI | Streptavidin | / | 0.506 | |
| 1z3n | 3NA | Aldose reductase | 1.1.1.21 | 0.504 | |
| 3lz5 | LDT | Aldose reductase | 1.1.1.21 | 0.503 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.503 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.501 | |
| 1frb | ZST | Aldose reductase-related protein 2 | / | 0.500 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.500 | |
| 2psj | CEI | Renilla-luciferin 2-monooxygenase | 1.13.12.5 | 0.500 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.499 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.499 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.498 | |
| 4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.498 | |
| 2duz | ZST | Aldose reductase | 1.1.1.21 | 0.497 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.497 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.497 | |
| 4yu1 | 53N | Aldose reductase | 1.1.1.21 | 0.497 | |
| 5liu | 388 | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.497 | |
| 2i17 | LDT | Aldose reductase | 1.1.1.21 | 0.496 | |
| 2pdm | ZST | Aldose reductase | 1.1.1.21 | 0.496 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.496 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.496 | |
| 1ah3 | TOL | Aldose reductase | 1.1.1.21 | 0.495 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.495 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.495 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.495 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.494 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.494 | |
| 4wev | SUZ | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.494 | |
| 2fz8 | ZST | Aldose reductase | 1.1.1.21 | 0.492 | |
| 2pdi | ZST | Aldose reductase | 1.1.1.21 | 0.492 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.492 | |
| 1el3 | I84 | Aldose reductase | 1.1.1.21 | 0.491 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.491 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.490 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.490 | |
| 2nvc | ITA | Aldose reductase | 1.1.1.21 | 0.489 | |
| 2pdh | 47D | Aldose reductase | 1.1.1.21 | 0.489 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.489 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.489 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.488 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.488 | |
| 3bur | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.488 | |
| 3ghr | LDT | Aldose reductase | 1.1.1.21 | 0.488 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.488 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.488 | |
| 2hvo | ZST | Aldose reductase | 1.1.1.21 | 0.487 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.487 | |
| 3o9l | LPN | Renin | 3.4.23.15 | 0.487 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.487 | |
| 1iei | ZES | Aldose reductase | 1.1.1.21 | 0.486 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.486 | |
| 2dux | ZST | Aldose reductase | 1.1.1.21 | 0.485 | |
| 2dv0 | ZST | Aldose reductase | 1.1.1.21 | 0.485 | |
| 2j7c | IDE | Beta-glucosidase A | 3.2.1.21 | 0.485 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.485 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.485 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.485 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.484 | |
| 1t40 | ID5 | Aldose reductase | 1.1.1.21 | 0.484 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.484 | |
| 3t31 | DCQ | Sulfide-quinone reductase | / | 0.484 | |
| 4ga8 | SBI | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.484 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.483 | |
| 2iki | 388 | Aldose reductase | 1.1.1.21 | 0.483 | |
| 3c1o | NAP | Eugenol synthase | / | 0.483 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.483 | |
| 2iqd | LPA | Aldose reductase | 1.1.1.21 | 0.482 | |
| 2pdq | 47D | Aldose reductase | 1.1.1.21 | 0.482 | |
| 3fx4 | FX4 | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.482 | |
| 1e1f | PSG | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.481 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 1q13 | TES | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.481 | |
| 3lql | LDT | Aldose reductase | 1.1.1.21 | 0.481 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.481 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.481 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.480 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.479 | |
| 2fzd | TOL | Aldose reductase | 1.1.1.21 | 0.479 | |
| 2pdu | 393 | Aldose reductase | 1.1.1.21 | 0.479 | |
| 4bjc | RPB | Tankyrase-2 | 2.4.2.30 | 0.479 | |
| 4gab | FID | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.479 | |
| 4gca | 2X9 | Aldose reductase | 1.1.1.21 | 0.479 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.478 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.477 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.477 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.477 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.476 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.476 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.475 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.475 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.475 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.475 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.475 | |
| 2vq3 | NAP | Metalloreductase STEAP3 | / | 0.474 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.473 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.473 | |
| 2pdn | 47D | Aldose reductase | 1.1.1.21 | 0.473 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.473 | |
| 3lbo | LDT | Aldose reductase | 1.1.1.21 | 0.473 | |
| 3m64 | 393 | Aldose reductase | 1.1.1.21 | 0.473 | |
| 3ug8 | IMN | Aldo-keto reductase family 1 member C3 | / | 0.473 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.473 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.473 | |
| 1dpm | EBP | Parathion hydrolase | 3.1.8.1 | 0.472 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.472 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.472 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.472 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.472 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.472 | |
| 4daj | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.472 | |
| 1ef3 | FID | Aldose reductase | 1.1.1.21 | 0.471 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.471 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.471 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.471 | |
| 1t41 | ID5 | Aldose reductase | 1.1.1.21 | 0.471 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.471 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.471 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.470 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.470 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.470 | |
| 3cfo | GMP | DNA-directed DNA polymerase | / | 0.470 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.470 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.470 | |
| 4jq2 | SUZ | Aldo-keto reductase family 1 member C2 | / | 0.470 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 1lke | DOG | Bilin-binding protein | / | 0.469 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2pdc | 393 | Aldose reductase | 1.1.1.21 | 0.469 | |
| 2pdp | 393 | Aldose reductase | 1.1.1.21 | 0.469 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 3cv6 | HXS | Aldo-keto reductase family 1 member C21 | / | 0.468 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.467 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.467 | |
| 2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.467 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.467 | |
| 2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.467 | |
| 4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.467 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.467 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.467 | |
| 5bn3 | ADP | NEQ263 | / | 0.467 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 3c4h | DRL | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.466 | |
| 3cv7 | C2U | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.466 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.466 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.466 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.466 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.466 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.466 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.466 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.466 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.465 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.465 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.465 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.465 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.465 | |
| 5d1b | TSN | Histone deacetylase 8 | 3.5.1.98 | 0.465 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.464 | |
| 2ipj | FFA | Aldo-keto reductase family 1 member C2 | / | 0.464 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 4dbu | BT9 | Aldo-keto reductase family 1 member C3 | / | 0.464 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.464 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.464 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.464 | |
| 1afs | TES | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.463 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1z89 | 62P | Aldose reductase | 1.1.1.21 | 0.463 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.463 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.463 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2fz9 | ZST | Aldose reductase | 1.1.1.21 | 0.462 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.462 | |
| 4j7h | TRH | PCZA361.3 | / | 0.462 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.462 | |
| 4jtp | ASC | Ribosome inactivating protein | / | 0.462 | |
| 5dsg | 0HK | Muscarinic acetylcholine receptor M4 | / | 0.462 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.461 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.461 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.461 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.461 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3n3b | FMN | Protein NrdI | / | 0.461 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.461 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 3u8f | FGM | Ribosome inactivating protein | / | 0.461 | |
| 3zo7 | K6H | Muconolactone Delta-isomerase | / | 0.461 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.461 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.461 | |
| 1enp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.460 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 1uhj | CZB | Aequorin-2 | / | 0.460 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.460 | |
| 3m4h | 388 | Aldose reductase | 1.1.1.21 | 0.460 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.460 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4gn6 | TYL | Lactoperoxidase | 1.11.1.7 | 0.460 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.460 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.460 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.460 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit alpha | 1.2.4.4 | 0.459 | |
| 1umc | TDP | 2-oxoisovalerate dehydrogenase subunit beta | 1.2.4.4 | 0.459 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 2vqq | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.459 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.459 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 4hmn | 16J | Aldo-keto reductase family 1 member C3 | / | 0.459 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.459 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.458 | |
| 2f38 | 15M | Aldo-keto reductase family 1 member C3 | / | 0.458 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.458 | |
| 2pzn | 393 | Aldose reductase | 1.1.1.21 | 0.458 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.458 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.458 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 3t42 | 3T4 | Aldose reductase | 1.1.1.21 | 0.458 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.457 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.457 | |
| 2cbq | TH2 | Neocarzinostatin | / | 0.457 | |
| 2ikh | LIT | Aldose reductase | 1.1.1.21 | 0.457 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.457 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.457 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.457 | |
| 3mb9 | ZST | Aldose reductase | 1.1.1.21 | 0.457 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4el9 | AFE | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.457 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.457 | |
| 1isg | AGS | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 | 3.2.2.6 | 0.456 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.456 | |
| 2pdx | ZST | Aldose reductase | 1.1.1.21 | 0.456 | |
| 2qcx | PF1 | Aminopyrimidine aminohydrolase | / | 0.456 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.456 | |
| 4a33 | PS8 | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4bmp | FMN | Protein NrdI | / | 0.456 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.455 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.455 | |
| 2pdj | 393 | Aldose reductase | 1.1.1.21 | 0.455 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.455 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3qji | MGP | Ribosome inactivating protein | / | 0.455 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.455 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.455 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.455 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.454 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.454 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.454 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.454 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.454 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.454 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.454 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.454 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.454 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.454 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.453 | |
| 2bd0 | BIO | Sepiapterin reductase | / | 0.453 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.453 | |
| 2hzq | STR | Apolipoprotein D | / | 0.453 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.453 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.453 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 3hfb | ML4 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.453 | |
| 4xcz | T3Q | Qdtf | / | 0.453 | |
| 5bv3 | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.453 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1rvv | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.452 | |
| 3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.452 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.452 | |
| 3gn2 | AX8 | Pteridine reductase | / | 0.452 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4cby | KEE | Histone deacetylase 4 | 3.5.1.98 | 0.452 | |
| 4ixt | 1H1 | Halohydrin dehalogenase | / | 0.452 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.452 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.451 | |
| 1fml | RTL | Retinol dehydratase | / | 0.451 | |
| 1qy2 | IPZ | Major urinary protein 1 | / | 0.451 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.451 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.451 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.451 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.451 | |
| 3ojg | HL4 | Phosphotriesterase | / | 0.451 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.451 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.451 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.451 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1pj6 | FOL | Dimethylglycine oxidase | 1.5.3.10 | 0.450 | |
| 1u2r | SO1 | Elongation factor 2 | / | 0.450 | |
| 2hv5 | ZST | Aldose reductase | 1.1.1.21 | 0.450 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.450 | |
| 3len | ZST | Aldose reductase | 1.1.1.21 | 0.450 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.450 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4jhi | EMU | Nodulin-13 | / | 0.450 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.450 | |
| 4xwt | U5P | Ribonuclease J | / | 0.450 | |
| 5jjr | SAH | Genome polyprotein | / | 0.450 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.449 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.449 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.449 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.449 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 2v57 | PRL | TetR family transcriptional regulator | / | 0.449 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.449 | |
| 3d5f | L41 | Peroxisome proliferator-activated receptor delta | / | 0.449 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.449 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.449 | |
| 4emr | MGP | Ribosome inactivating protein | / | 0.449 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 5agp | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.448 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.448 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.448 | |
| 2bu5 | TF1 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.448 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.448 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2zoz | ET | Transcriptional regulator | / | 0.448 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.448 | |
| 3lcc | SAH | Thiocyanate methyltransferase 1 | / | 0.448 | |
| 3ld5 | LDT | Aldose reductase | 1.1.1.21 | 0.448 | |
| 3ogw | IMN | Lactoperoxidase | 1.11.1.7 | 0.448 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.448 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.448 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.448 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.448 | |
| 5bn4 | ANP | V-type ATP synthase alpha chain | / | 0.448 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.447 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.447 | |
| 1s36 | CEI | Obelin | / | 0.447 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.447 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.447 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.447 | |
| 2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.447 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.447 | |
| 3n39 | FMN | Protein NrdI | / | 0.447 | |
| 3p9t | TCL | Repressor | / | 0.447 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.447 | |
| 4h6p | FMN | Chromate reductase | / | 0.447 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.447 | |
| 5ilw | URI | Ribosome inactivating protein | / | 0.447 | |
| 1hlk | 113 | Metallo-beta-lactamase type 2 | / | 0.446 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1wm1 | PTB | Proline iminopeptidase | 3.4.11.5 | 0.446 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.446 | |
| 2jj1 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.446 | |
| 2jj1 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.446 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.446 | |
| 4j7g | TRH | PCZA361.3 | / | 0.446 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.446 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1jt6 | DEQ | HTH-type transcriptional regulator QacR | / | 0.445 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1uxv | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2jj2 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.445 | |
| 2jj2 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.445 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.445 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.445 | |
| 3nxo | D2B | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.445 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 4hrq | AZG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.445 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4mm9 | FVX | Na(+):neurotransmitter symporter (Snf family) | / | 0.445 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.445 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.445 | |
| 1a8t | 061 | Metallo-beta-lactamase type 2 | / | 0.444 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.444 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1u3g | THF | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.444 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.444 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.444 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.444 | |
| 2y1w | 849 | Histone-arginine methyltransferase CARM1 | / | 0.444 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.444 | |
| 3fu9 | KIB | Laccase-1 | 1.10.3.2 | 0.444 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 3mc5 | 393 | Aldose reductase | 1.1.1.21 | 0.444 | |
| 3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.444 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 3r58 | NPS | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 3r6i | JMS | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 4f79 | P53 | Putative phospho-beta-glucosidase | / | 0.444 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 4jpg | 1OX | Pyruvate kinase PKM | 2.7.1.40 | 0.444 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.444 | |
| 4lsa | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.444 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1gvh | FAD | Flavohemoprotein | / | 0.443 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.443 | |
| 2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.443 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3nlv | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.443 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.443 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.443 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.443 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4lwx | MU2 | Ribosome inactivating protein | / | 0.443 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.442 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1wpg | ADP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.442 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.442 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.442 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3dz2 | A8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.442 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.442 | |
| 4boe | CLR | Japanin | / | 0.442 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 4hhy | 15R | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.442 | |
| 5epe | SAH | Uncharacterized protein | / | 0.442 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.442 | |
| 1ddt | APU | Diphtheria toxin | / | 0.441 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1g60 | SAM | Modification methylase MboII | 2.1.1.72 | 0.441 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 2rd6 | 78P | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.441 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.441 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.441 | |
| 3uwe | VJJ | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4gr9 | 372 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.441 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.441 | |
| 9mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.441 | |
| 1gnw | GTX | Glutathione S-transferase F2 | 2.5.1.18 | 0.440 | |
| 1lud | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1t48 | BB3 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.440 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2xej | OKD | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.440 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.440 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 3znq | SS8 | D-amino-acid oxidase | 1.4.3.3 | 0.440 | |
| 4at5 | MUJ | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.440 | |
| 4dkb | DUN | Deoxyuridine triphosphatase, putative | / | 0.440 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.440 | |
| 4kyk | IMN | Lactoylglutathione lyase | 4.4.1.5 | 0.440 |