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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ii3CAOLipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial2.3.1.168

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2ii3CAOLipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial2.3.1.1681.000
2ii5CO6Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial2.3.1.1680.629
4lcjNADC-terminal-binding protein 2/0.502
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.501
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.496
1xe65FPPlasmepsin-23.4.23.390.493
3nxxNDPDihydrofolate reductase1.5.1.30.492
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.491
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.490
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.489
2g8yNADHydroxycarboxylate dehydrogenase B/0.488
3p62FMNPentaerythritol tetranitrate reductase/0.487
2dvlFADAcyl-CoA dehydrogenase/0.486
4abkAR6Poly [ADP-ribose] polymerase 142.4.2.300.486
4u0zAPCAdenosine monophosphate-protein transferase FICD2.7.7.n10.486
3r95ACOMccE protein/0.485
1t2cNAIL-lactate dehydrogenase1.1.1.270.482
3f3sNADLambda-crystallin homolog/0.482
3a0tADPSensor histidine kinase/0.481
4a862ANMajor pollen allergen Bet v 1-A/0.481
1oklMNSCarbonic anhydrase 24.2.1.10.480
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.480
2y0mACOHistone acetyltransferase KAT8/0.480
4uugPXGBranched-chain amino acid aminotransferase, putative/0.480
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.479
3zcsCAWGlycogen phosphorylase, muscle form2.4.1.10.478
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.477
4bb3KKAIsopenicillin N synthase1.21.3.10.477
1nm6L86Prothrombin3.4.21.50.476
3h3fNAIL-lactate dehydrogenase A chain1.1.1.270.476
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.475
1jqiFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial/0.475
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.475
2zi224UProthrombin3.4.21.50.475
3vmmP0DAlanine--anticapsin ligase/0.475
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.475
1dgmADNAdenosine kinase2.7.1.200.474
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.474
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.474
2rlcCHDCholoylglycine hydrolase3.5.1.240.474
1x8lOXRRetinol dehydratase/0.473
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.473
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.473
2w3bNDPDihydrofolate reductase1.5.1.30.473
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.473
3lqfNADGalactitol dehydrogenase/0.473
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.473
4imoPWZProstaglandin-H2 D-isomerase5.3.99.20.473
4lxb7R9Prothrombin3.4.21.50.473
1xe55FEPlasmepsin-23.4.23.390.472
4ewo996Beta-secretase 13.4.23.460.472
1gj5130Prothrombin3.4.21.50.471
1jueFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.471
1nbmATPATP synthase subunit alpha, mitochondrial/0.471
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.471
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.471
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.470
3c35KAIGlutamate receptor ionotropic, kainate 1/0.470
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.470
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.470
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.469
3h3sH15Collagen type IV alpha-3-binding protein/0.469
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.468
1txzAPRProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.468
2fznFADBifunctional protein PutA1.5.5.20.468
2jh6894Prothrombin3.4.21.50.468
2zhf49UProthrombin3.4.21.50.468
4a802ANMajor pollen allergen Bet v 1-A/0.468
4a83DXCMajor pollen allergen Bet v 1-A/0.468
2bjfDXCCholoylglycine hydrolase3.5.1.240.467
2givACOHistone acetyltransferase KAT8/0.467
3h06VBPGlutamate receptor 2/0.467
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
3v2uATPProtein GAL3/0.467
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
2ignFADPyranose 2-oxidase/0.466
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.466
2xw7NDPDihydrofolate reductase/0.466
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.466
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.466
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
4m83ERYOleandomycin glycosyltransferase2.4.10.466
5efwFMNNPH1-1/0.466
1o5gCR9Prothrombin3.4.21.50.465
2f3rG5PGuanylate kinase2.7.4.80.465
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.465
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.465
4ax9N5NProthrombin3.4.21.50.465
4k8s1QTBeta-secretase 13.4.23.460.465
1me6IVSPlasmepsin-23.4.23.390.464
1w6hTITPlasmepsin-23.4.23.390.464
1zgv501Prothrombin3.4.21.50.464
2ahrNAPPyrroline-5-carboxylate reductase/0.464
2gtnLIEMitogen-activated protein kinase 14/0.464
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.464
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
3ggcH26Hypoxanthine-guanine phosphoribosyltransferase2.4.2.80.464
3ggj25HHypoxanthine-guanine phosphoribosyltransferase2.4.2.80.464
3jzdNADMaleylacetate reductase/0.464
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.464
1nvtNAPShikimate dehydrogenase (NADP(+))/0.463
2v1aFMNNPH1-1/0.463
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
4ef9FMNDihydroorotate dehydrogenase (fumarate)/0.463
4isk1JYThymidylate synthase/0.463
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.463
1h73ANPHomoserine kinase2.7.1.390.462
1u1gBBBUridine phosphorylase2.4.2.30.462
2v3hI25Prothrombin3.4.21.50.462
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.462
2w9hTOPDihydrofolate reductase1.5.1.30.462
3c3nFMNDihydroorotate dehydrogenase (fumarate)1.3.98.10.462
3oafOAGDihydrofolate reductase1.5.1.30.462
3wagTYDGlycosyltransferase/0.462
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.461
1psa0ZLPepsin A3.4.23.10.461
2pksG44Prothrombin3.4.21.50.461
2pswCOAN-alpha-acetyltransferase 50/0.461
2qbmCAMCamphor 5-monooxygenase1.14.15.10.461
3dhk23UProthrombin3.4.21.50.461
3gstGPRGlutathione S-transferase Mu 12.5.1.180.461
3gvhNADMalate dehydrogenase/0.461
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.461
3p0fBAUUridine phosphorylase 22.4.2.30.461
3tfyCOAN-alpha-acetyltransferase 502.3.10.461
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.461
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.461
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.461
1c4uIH1Prothrombin3.4.21.50.460
1h74ADPHomoserine kinase2.7.1.390.460
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.460
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3axbFADPutative oxidoreductase/0.460
3b2eADPATPase GET3/0.460
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.460
3uylTYDProbable NDP-rhamnosyltransferase/0.460
4a87NARMajor pollen allergen Bet v 1-A/0.460
5dp2NAPCurF/0.460
5fsxADPUncharacterized protein/0.460
1bwlFMNNADPH dehydrogenase 11.6.99.10.459
1culFOKAdenylate cyclase type 2/0.459
1culFOKAdenylate cyclase type 5/0.459
1g1aNADdTDP-glucose 4,6-dehydratase/0.459
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.459
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.459
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.459
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.459
2he5NDPAldo-keto reductase family 1 member C211.1.10.459
2jb4A14Isopenicillin N synthase1.21.3.10.459
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.459
2x9dITCTetracycline repressor protein class D/0.459
3aezGDPPantothenate kinase2.7.1.330.459
3d2pCOAAmino-acid acetyltransferase/0.459
3eksCY9Actin-5C/0.459
3hl0NADMaleylacetate reductase/0.459
4wbdADPPutative cysteine ligase BshC/0.459
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.459
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.458
1i6xCMPcAMP-activated global transcriptional regulator CRP/0.458
1t4u81AProthrombin3.4.21.50.458
2bslFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.458
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.458
2vbdV10Isopenicillin N synthase1.21.3.10.458
2x7hPFNProstaglandin reductase 310.458
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3rdqDTBStreptavidin/0.458
4du82P0Mevalonate diphosphate decarboxylase/0.458
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.458
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.458
1d3dBZTProthrombin3.4.21.50.457
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.457
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.457
2dxdANPNucleoside diphosphate kinase2.7.4.60.457
2ebaFADPutative glutaryl-CoA dehydrogenase/0.457
3ajrNADNDP-sugar epimerase/0.457
3bk2U5PRibonuclease J/0.457
3h3t16HCollagen type IV alpha-3-binding protein/0.457
4q71FADBifunctional protein PutA/0.457
5a0112VO-glycosyltransferase/0.457
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
3c1y2BADNA integrity scanning protein DisA/0.456
3clrFADElectron transfer flavoprotein subunit alpha/0.456
3in6FMNUncharacterized protein/0.456
3mauEXTPutative sphingosine-1-phosphate lyase/0.456
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.456
3uu114BAnthranilate phosphoribosyltransferase/0.456
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.456
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.455
1n2vBDIQueuine tRNA-ribosyltransferase2.4.2.290.455
1ta6177Prothrombin3.4.21.50.455
1tehNADAlcohol dehydrogenase class-31.1.1.10.455
1tl7FOKAdenylate cyclase type 2/0.455
1tl7FOKAdenylate cyclase type 5/0.455
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.455
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.455
2r2mI50Prothrombin3.4.21.50.455
2wu4HBPAcetylcholinesterase3.1.1.70.455
2zsaADPPantothenate kinase2.7.1.330.455
3c34KAIGlutamate receptor ionotropic, kainate 1/0.455
3nsh957Beta-secretase 13.4.23.460.455
3ty3GGGHomoisocitrate dehydrogenase1.1.1.870.455
4asuADPATP synthase subunit alpha, mitochondrial/0.455
4djy0KRBeta-secretase 13.4.23.460.455
4dpi0N1Beta-secretase 13.4.23.460.455
4dpuAGSMevalonate diphosphate decarboxylase/0.455
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.455
4i0i957Beta-secretase 13.4.23.460.455
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.455
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.454
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.454
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.454
2c12FADNitroalkane oxidase1.7.3.10.454
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2rcyNAPPyrroline-5-carboxylate reductase/0.454
3r96ACOMccE protein/0.454
3uk6ADPRuvB-like 23.6.4.120.454
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.454
4g7gVFVLanosterol 14-alpha-demethylase/0.454
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.454
5dbgNADIridoid synthase1.3.1.990.454
1aa6MGDFormate dehydrogenase H1.1.99.330.453
1eiiRTLRetinol-binding protein 2/0.453
1kqwRTLCellular retinol-binding protein type II/0.453
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.453
1skmSAHModification methylase HhaI2.1.1.370.453
1trgCB3Thymidylate synthase/0.453
2iviACWIsopenicillin N synthase1.21.3.10.453
3aosJH2Hemolymph juvenile hormone binding protein/0.453
3b70NAPEnoyl reductase LovC10.453
3ekuCY9Actin-5C/0.453
3imgBZ2Pantothenate synthetase6.3.2.10.453
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.453
4dpf0LGBeta-secretase 13.4.23.460.453
4exg916Beta-secretase 13.4.23.460.453
4jx1CAHCamphor 5-monooxygenase1.14.15.10.453
4mlp2CXCryptochrome-2/0.453
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.453
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
1d3pBT3Prothrombin3.4.21.50.452
1hfqMOTDihydrofolate reductase1.5.1.30.452
1powFADPyruvate oxidase1.2.3.30.452
2ifaFMNUncharacterized protein/0.452
2iyfERYOleandomycin glycosyltransferase2.4.10.452
2rgoFADAlpha-Glycerophosphate Oxidase/0.452
2uuk897Prothrombin3.4.21.50.452
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.452
2vn0TDZCytochrome P450 2C8/0.452
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
3hatGLY_VAL_ARG_RNGProthrombin3.4.21.50.452
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.452
4cojDTPUncharacterized protein/0.452
4rn615UProthrombin3.4.21.50.452
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.452
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
4ycpFMNtRNA-dihydrouridine(16) synthase/0.452
1e3eNAIAlcohol dehydrogenase 41.1.1.10.451
1f8gNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.451
1rrmAPRLactaldehyde reductase1.1.1.770.451
1w0kADPATP synthase subunit alpha, mitochondrial/0.451
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.451
2cftPLPPyridoxal phosphate phosphatase/0.451
2jh5895Prothrombin3.4.21.50.451
2q0lNAPThioredoxin reductase1.8.1.90.451
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.451
3c1kT15Prothrombin3.4.21.50.451
3coy53HPantothenate synthetase6.3.2.10.451
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3hdyGDUUDP-galactopyranose mutase/0.451
3q33ACOHistone acetyltransferase RTT1092.3.1.480.451
3to6LYS_CMCHistone acetyltransferase ESA1/0.451
4eb5PLPCysteine desulfurase IscS 2/0.451
4i1iNADMalate dehydrogenase/0.451
4irnFADAnaB/0.451
4lxk1YTBeta-secretase 13.4.23.460.451
5gpbGPMGlycogen phosphorylase, muscle form2.4.1.10.451
1ai9NDPDihydrofolate reductase1.5.1.30.450
1dhrNADDihydropteridine reductase1.5.1.340.450
1lquNDPNADPH-ferredoxin reductase FprA1.18.1.20.450
2g1n1IGRenin3.4.23.150.450
2g247IGRenin3.4.23.150.450
3gep24HHypoxanthine-guanine phosphoribosyltransferase2.4.2.80.450
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
3p82FMNPentaerythritol tetranitrate reductase/0.450
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.450
4bfwZVWPantothenate kinase2.7.1.330.450
4n3l2FNProthrombin3.4.21.50.450
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.450
1bsvNDPGDP-L-fucose synthase/0.449
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1o2g696Prothrombin3.4.21.50.449
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
1yqxNAPSinapyl alcohol dehydrogenase/0.449
2g1o2IGRenin3.4.23.150.449
2g76NADD-3-phosphoglycerate dehydrogenase1.1.1.950.449
2y65ADPKinesin heavy chain/0.449
3a37ADPATPase GET3/0.449
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.449
3gwlFADFAD-linked sulfhydryl oxidase1.8.3.20.449
3owaFADAcyl-CoA dehydrogenase/0.449
3p74FMNPentaerythritol tetranitrate reductase/0.449
3r7kFDAProbable acyl CoA dehydrogenase/0.449
3vhaVHAHeat shock protein HSP 90-alpha/0.449
4dptAGSMevalonate diphosphate decarboxylase/0.449
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.449
4xiwAZMCarbonic anhydrase, alpha type/0.449
4yaoFMNNADPH--cytochrome P450 reductase/0.449
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.449
3vw7VPXProteinase-activated receptor 1/0.449
1drhNAPDihydrofolate reductase1.5.1.30.448
1mbbEEBUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.448
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
2geuCOKPantothenate kinase2.7.1.330.448
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.448
2zda32UProthrombin3.4.21.50.448
2zhe13UProthrombin3.4.21.50.448
3dt2GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.448
3gbuATPUncharacterized sugar kinase PH14592.7.10.448
3h2sNDPPutative NADH-flavin reductase/0.448
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.448
3isjA8DPantothenate synthetase6.3.2.10.448
3nbvANPKetohexokinase/0.448
3qlsNDPDihydrofolate reductase1.5.1.30.448
3qwbNDPProbable quinone oxidoreductase1.6.5.50.448
3rsv3RSBeta-secretase 13.4.23.460.448
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.448
3v2bAR6Poly [ADP-ribose] polymerase 152.4.2.300.448
3zcnATPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.448
3zxsFADDeoxyribodipyrimidine photolyase-related protein/0.448
4dbzNDPPutative ketoacyl reductase1.3.10.448
4gsuDWZL,D-transpeptidase 22.3.20.448
4m9aFDAAcyl-CoA dehydrogenase/0.448
4r81FMNPredicted NADH dehydrogenase/0.448
4xr9NADCalS8/0.448
4z24FADPutative GMC-type oxidoreductase R13510.448
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.448
5jscFADPutative acyl-CoA dehydrogenase/0.448
1dr3TAPDihydrofolate reductase1.5.1.30.447
1g6oADPCag alpha/0.447
1lbcCYZGlutamate receptor 2/0.447
1p0hACOMycothiol acetyltransferase2.3.1.1890.447
1rfuADPPyridoxal kinase2.7.1.350.447
2a94AP0L-lactate dehydrogenase1.1.1.270.447
2wzwNDPNitroreductase NfnB/0.447
2zc922UProthrombin3.4.21.50.447
3biu10UProthrombin3.4.21.50.447
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
3pfdFDAAcyl-CoA dehydrogenase FadE25/0.447
3rk1ATPN-type ATP pyrophosphatase superfamily/0.447
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.447
4ambDUDPutative glycosyl transferase/0.447
4iarERM5-hydroxytryptamine receptor 1B/0.447
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.447
4k6fNAPPutative Acetoacetyl-CoA reductase/0.447
4k9h1QUBeta-secretase 13.4.23.460.447
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.447
1amoFMNNADPH--cytochrome P450 reductase/0.446
1d4pBPPProthrombin3.4.21.50.446
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.446
2bdyUNBProthrombin3.4.21.50.446
2dvoITTdITP/XTP pyrophosphatase3.6.1.190.446
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.446
2qjoNADBifunctional NMN adenylyltransferase/Nudix hydrolase2.7.7.10.446
2rqfJH3Hemolymph juvenile hormone binding protein/0.446
2w3mFOLDihydrofolate reductase1.5.1.30.446
2xviFADPutative flavin-containing monooxygenase/0.446
2zdv37UProthrombin3.4.21.50.446
3bg7FADPyranose 2-oxidase/0.446
3d84NDPDihydrofolate reductase1.5.1.30.446
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.446
3kb1ADPIron-sulfur cluster carrier protein/0.446
3ox4NADAlcohol dehydrogenase 21.1.1.10.446
3phiNDPShikimate dehydrogenase (NADP(+))/0.446
3sf6FDAGlutaryl-CoA dehydrogenase/0.446
4an4DUDPutative glycosyl transferase/0.446
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.446
4p13FADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.446
4djhJDCKappa-type opioid receptor/0.446
1a42BZUCarbonic anhydrase 24.2.1.10.445
1blzACVIsopenicillin N synthase1.21.3.10.445
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1hb3SCVIsopenicillin N synthase1.21.3.10.445
1i5cADPChemotaxis protein CheA2.7.13.30.445
1j9zFADNADPH--cytochrome P450 reductase/0.445
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.445
1njjORXOrnithine decarboxylase/0.445
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.445
2c20NADUDP-glucose 4-epimerase/0.445
2d81RB3Poly(3-hydroxybutyrate) depolymerase/0.445
2dftADPShikimate kinase2.7.1.710.445
2i7pACOPantothenate kinase 32.7.1.330.445
2wf3ZY3Beta-secretase 13.4.23.460.445
3dm5GDPSignal recognition particle 54 kDa protein/0.445
3drcMTXDihydrofolate reductase1.5.1.30.445
3ivgFG5Pantothenate synthetase6.3.2.10.445
3ncrADPNitrogen regulatory protein P-II (GlnB-2)/0.445
3opmLUIDipeptidyl peptidase 4/0.445
3oqkS52Renin3.4.23.150.445
4az29MUProthrombin3.4.21.50.445
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.445
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
4q0kGA3Phytohormone-binding protein/0.445
4yvz3ATDNA integrity scanning protein DisA/0.445
1i59ANPChemotaxis protein CheA2.7.13.30.444
1jwtBLIProthrombin3.4.21.50.444
1mjaCOAHistone acetyltransferase ESA1/0.444
1p0fNAPNADP-dependent alcohol dehydrogenase1.1.1.20.444
1xm1GAHProthrombin3.4.21.50.444
2a5kAZPReplicase polyprotein 1ab3.4.220.444
2aj4ANPGalactokinase2.7.1.60.444
2cv2GSUGlutamate--tRNA ligase6.1.1.170.444
2gtbAZPOrf1ab polyprotein/0.444
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
2hmySAMModification methylase HhaI2.1.1.370.444
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2qenADPWalker-Type ATPase/0.444
2rc4ACOHistone acetyltransferase KAT6A/0.444
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.444
2w2lNADD-mandelate dehydrogenase/0.444
3br3ETHTH-type transcriptional regulator QacR/0.444
3cukFADD-amino-acid oxidase1.4.3.30.444
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.444
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3lpiZ74Beta-secretase 13.4.23.460.444
3zoiM2WIsopenicillin N synthase1.21.3.10.444
4dxlC5P4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.444
4fqsLYAThymidylate synthase ThyA/0.444
4i6gFADCryptochrome-2/0.444
4okw198Androgen receptor/0.444
4q72FADBifunctional protein PutA/0.444
5k2cZMAAdenosine receptor A2a/0.444
1df7MTXDihydrofolate reductase1.5.1.30.443
1guyNADMalate dehydrogenase/0.443
1mhtSAHModification methylase HhaI2.1.1.370.443
1obnASVIsopenicillin N synthase1.21.3.10.443
1srjNABStreptavidin/0.443
1t4v14AProthrombin3.4.21.50.443
1ur5NADMalate dehydrogenase/0.443
1y7tNDPMalate dehydrogenase/0.443
2a84ATPPantothenate synthetase6.3.2.10.443
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.443
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.443
2v3oI26Prothrombin3.4.21.50.443
2zfr46UProthrombin3.4.21.50.443
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.443
3kjgADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.443
3oeeANPATP synthase subunit alpha, mitochondrial/0.443
3oeeANPATP synthase subunit beta, mitochondrial3.6.3.140.443
4b4vL34Bifunctional protein FolD/0.443
4c49HCYCorticosteroid-binding globulin/0.443
4ehyADPTetraacyldisaccharide 4'-kinase/0.443
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.443
4gcmNAPThioredoxin reductase1.8.1.90.443
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4gs4ACOAlpha-tubulin N-acetyltransferase 1/0.443
4hj6FMNLOV protein/0.443
4ht2V50Carbonic anhydrase 124.2.1.10.443
4m6jNDPDihydrofolate reductase1.5.1.30.443
4obuPLPPyridoxal-dependent decarboxylase domain protein/0.443
4rgqNDPGlycerol-1-phosphate dehydrogenase [NAD(P)+]/0.443
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.443
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.443
5ahsFADAcyl-CoA dehydrogenase/0.443
1fmlRTLRetinol dehydratase/0.442
1ppjANYCytochrome b/0.442
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1t2bCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.442
1z71L17Prothrombin3.4.21.50.442
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.442
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2cvqNDPMalate dehydrogenase/0.442
2g1s4IGRenin3.4.23.150.442
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.442
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.442
2ou2ACOHistone acetyltransferase KAT5/0.442
2p4j23IBeta-secretase 13.4.23.460.442
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.442
3a1nNADNDP-sugar epimerase/0.442
3eqlMXPDNA-directed RNA polymerase subunit beta/0.442
3eqlMXPDNA-directed RNA polymerase subunit beta'/0.442
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.442
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.442
3gw9VNILanosterol 14-alpha-demethylase/0.442
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3qe2FMNNADPH--cytochrome P450 reductase/0.442
3qgf46FGenome polyprotein2.7.7.480.442
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
4a4zANPAntiviral helicase SKI23.6.4.130.442
4a81DXCMajor pollen allergen Bet v 1-A/0.442
4djaFAD(6-4) photolyase/0.442
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4oznATPAmmonium transporter/0.442
4oztP1AEcdysone receptor, putative/0.442
4z26FADPutative GMC-type oxidoreductase R13510.442
1cjtFOKAdenylate cyclase type 2/0.441
1cjtFOKAdenylate cyclase type 5/0.441
1ia1NDPDihydrofolate reductase1.5.1.30.441
1mueCDDProthrombin3.4.21.50.441
1rx1NAPDihydrofolate reductase1.5.1.30.441
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.441
2daaDCSD-alanine aminotransferase2.6.1.210.441
2g0lFLNNeocarzinostatin/0.441
2g1r3IGRenin3.4.23.150.441
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.441
2hu2NADC-terminal binding protein 1/0.441
2jgsBTNAvidin/0.441
2po3T4K4-dehydrase/0.441
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.441
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.441
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.441
2yj5ATPCopper-transporting ATPase/0.441
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.441
3c36KAIGlutamate receptor ionotropic, kainate 1/0.441
3iaaTYDCalG2/0.441
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.441
3q43D66M1 family aminopeptidase3.4.110.441
3tjlFMNNADPH dehydrogenase/0.441
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.441
4ddhMS0Pantothenate synthetase6.3.2.10.441
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.441
4i9n1E5L-lactate dehydrogenase A chain1.1.1.270.441
4j7hTRHPCZA361.3/0.441
4la1FADThioredoxin glutathione reductase/0.441
4twnB96Ephrin type-A receptor 32.7.10.10.441
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.441
1cf3FADGlucose oxidase1.1.3.40.440
1d9i00PProthrombin3.4.21.50.440
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.440
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.440
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.440
1itzTPPTransketolase, chloroplastic2.2.1.10.440
1kqgMGDFormate dehydrogenase, nitrate-inducible, major subunit1.1.5.60.440
1kvkATPMevalonate kinase2.7.1.360.440
1kwqSG1Carbonic anhydrase 24.2.1.10.440
1rq1FADEndoplasmic oxidoreductin-11.8.40.440
1umkFADNADH-cytochrome b5 reductase 31.6.2.20.440
1ypgUIRProthrombin3.4.21.50.440
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.440
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.440
2ejzSAHDiphthine synthase/0.440
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.440
2fj1CTCTetracycline repressor protein class D/0.440
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.440
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.440
2ibzUQ6Cytochrome b/0.440
2po7CHDFerrochelatase, mitochondrial4.99.1.10.440
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.440
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.440
2ql6ADPNicotinamide riboside kinase 1/0.440
3b1dPLSBetaC-S lyase/0.440
3d4pNADL-lactate dehydrogenase 11.1.1.270.440
3imgBZ3Pantothenate synthetase6.3.2.10.440
3kej3EJCollagenase 33.4.240.440
4dl9NADS-(hydroxymethyl)glutathione dehydrogenase/0.440
4do30LAFatty-acid amide hydrolase 13.5.1.990.440
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.440
4epq0RRPoly(ADP-ribose) glycohydrolase/0.440
4f3xNADPutative aldehyde dehydrogenase/0.440
4fue7UPUrokinase-type plasminogen activator3.4.21.730.440
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4jldADPAdenylate kinase/0.440
4q73FADBifunctional protein PutA/0.440
4v2gCTCTetracycline repressor protein class D/0.440
5cfpC2EStimulator of interferon genes protein/0.440
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.440