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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ieiFRXGlycogen phosphorylase, muscle form2.4.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2ieiFRXGlycogen phosphorylase, muscle form2.4.1.11.000
2iegFRYGlycogen phosphorylase, muscle form2.4.1.10.532
1exv700Glycogen phosphorylase, liver form2.4.1.10.496
1l5s700Glycogen phosphorylase, liver form2.4.1.10.486