Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2id2NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase1.2.1.9

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2id2NAPNADP-dependent glyceraldehyde-3-phosphate dehydrogenase1.2.1.91.000
3bgxMEFThymidylate synthase/0.476
1ozvSAHRibulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic2.1.1.1270.465
2r26CMCCitrate synthase2.3.3.160.462
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.461
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.449
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.449
4nmdFDABifunctional protein PutA/0.449
1tj1FADBifunctional protein PutA1.5.5.20.448
1ky8NAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase/0.446
2fzmFADBifunctional protein PutA1.5.5.20.445
4a4wYFBPeroxisome proliferator-activated receptor gamma/0.444
5ctsCMCCitrate synthase, mitochondrial2.3.3.10.444
4zm6ACON-acetyl-beta-D glucosaminidase/0.443
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.442
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.442
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
3w8wFADPutative FAD-dependent oxygenase EncM/0.441
4bftZVTPantothenate kinase2.7.1.330.441
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441