Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2hut | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2hut | SAH | Diphthine synthase | / | 1.000 | |
| 2owk | SAH | Diphthine synthase | / | 0.853 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.837 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.832 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.792 | |
| 2p5f | SAH | Diphthine synthase | / | 0.790 | |
| 2ehl | SAH | Diphthine synthase | / | 0.778 | |
| 2e15 | SAH | Diphthine synthase | / | 0.774 | |
| 2p5c | SAH | Diphthine synthase | / | 0.769 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.765 | |
| 2owg | SAH | Diphthine synthase | / | 0.764 | |
| 2dsi | SAH | Diphthine synthase | / | 0.762 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.761 | |
| 2e8r | SAH | Diphthine synthase | / | 0.757 | |
| 2e17 | SAH | Diphthine synthase | / | 0.741 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.735 | |
| 2p6i | SAH | Diphthine synthase | / | 0.734 | |
| 2z6r | SAH | Diphthine synthase | / | 0.732 | |
| 2owu | SAH | Diphthine synthase | / | 0.730 | |
| 2emu | SAH | Diphthine synthase | / | 0.724 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.719 | |
| 2huv | SAH | Diphthine synthase | / | 0.716 | |
| 2ele | SAH | Diphthine synthase | / | 0.715 | |
| 2huq | SAH | Diphthine synthase | / | 0.711 | |
| 2p9d | SAH | Diphthine synthase | / | 0.711 | |
| 2dxx | SAH | Diphthine synthase | / | 0.707 | |
| 2eni | SAH | Diphthine synthase | / | 0.706 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.702 | |
| 2egs | SAH | Diphthine synthase | / | 0.701 | |
| 2e4n | SAH | Diphthine synthase | / | 0.695 | |
| 2el3 | SAH | Diphthine synthase | / | 0.694 | |
| 2ejk | SAH | Diphthine synthase | / | 0.693 | |
| 2p2x | SAH | Diphthine synthase | / | 0.693 | |
| 2p6k | SAH | Diphthine synthase | / | 0.692 | |
| 2e7r | SAH | Diphthine synthase | / | 0.687 | |
| 2emr | SAH | Diphthine synthase | / | 0.686 | |
| 2eeq | SAH | Diphthine synthase | / | 0.683 | |
| 2el0 | SAH | Diphthine synthase | / | 0.683 | |
| 2dxw | SAH | Diphthine synthase | / | 0.671 | |
| 2p6d | SAH | Diphthine synthase | / | 0.670 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.668 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.666 | |
| 1wng | SAH | Diphthine synthase | / | 0.664 | |
| 2pca | SAH | Diphthine synthase | / | 0.663 | |
| 2pck | SAH | Diphthine synthase | / | 0.662 | |
| 2dxv | SAH | Diphthine synthase | / | 0.661 | |
| 2eld | SAH | Diphthine synthase | / | 0.661 | |
| 2dsg | SAH | Diphthine synthase | / | 0.656 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.655 | |
| 2pcg | SAH | Diphthine synthase | / | 0.650 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.649 | |
| 2e07 | SAH | Diphthine synthase | / | 0.649 | |
| 2pcm | SAH | Diphthine synthase | / | 0.647 | |
| 1vce | SAH | Diphthine synthase | / | 0.646 | |
| 2e8h | SAH | Diphthine synthase | / | 0.646 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.646 | |
| 2e8s | SAH | Diphthine synthase | / | 0.630 | |
| 2dsh | SAH | Diphthine synthase | / | 0.627 | |
| 2pci | SAH | Diphthine synthase | / | 0.623 | |
| 2dek | SAH | Diphthine synthase | / | 0.622 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.616 | |
| 2eka | SAH | Diphthine synthase | / | 0.615 | |
| 2ejj | SAH | Diphthine synthase | / | 0.614 | |
| 2egb | SAH | Diphthine synthase | / | 0.608 | |
| 2pch | SAH | Diphthine synthase | / | 0.607 | |
| 2owf | SAH | Diphthine synthase | / | 0.604 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.600 | |
| 2hux | SAH | Diphthine synthase | / | 0.597 | |
| 2e8q | SAH | Diphthine synthase | / | 0.587 | |
| 2e08 | SAH | Diphthine synthase | / | 0.585 | |
| 2p6l | SAH | Diphthine synthase | / | 0.583 | |
| 2egl | SAH | Diphthine synthase | / | 0.576 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.566 | |
| 2en5 | SAH | Diphthine synthase | / | 0.558 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.557 | |
| 2e16 | SAH | Diphthine synthase | / | 0.555 | |
| 2ejz | SAH | Diphthine synthase | / | 0.553 | |
| 2owv | SAH | Diphthine synthase | / | 0.550 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.501 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.494 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.492 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.490 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.489 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.488 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.486 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.486 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.484 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.483 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.481 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.480 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.480 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.479 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.479 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.479 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.478 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.476 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.476 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.476 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.475 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.474 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.473 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.473 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.472 | |
| 1dg8 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.471 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.471 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.471 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.470 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.470 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.469 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.469 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.469 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.469 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.469 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.469 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.468 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.468 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.468 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.468 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.467 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.467 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.467 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.466 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.466 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.466 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.466 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.464 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.464 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.464 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 3a3g | DLZ | Lumazine protein | / | 0.464 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.464 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.464 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.464 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.463 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.463 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.463 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.463 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.463 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.463 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.463 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.462 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.462 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.462 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.462 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.462 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.461 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.461 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.461 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.461 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.460 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.460 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.460 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.460 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.460 | |
| 3zuy | TCH | Transporter | / | 0.460 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.460 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.459 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.459 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.459 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.459 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.458 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.458 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.458 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.458 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.457 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.457 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.457 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.457 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.457 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.457 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.457 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.457 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.456 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.456 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.456 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.456 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.456 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.456 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.456 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.456 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.455 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.455 | |
| 3u9e | COA | Lmo1369 protein | / | 0.455 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.455 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.455 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.455 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.454 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.454 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.454 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.454 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.454 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.454 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.454 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.454 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.454 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.454 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.454 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.453 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.453 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.453 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.453 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.453 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.453 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2y3s | TIR | TamL | / | 0.453 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4ohx | ADP | Protein clpf-1 | / | 0.453 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.453 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1vp6 | CMP | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.452 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
| 1z1f | STL | Resveratrol synthase | / | 0.452 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.452 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.452 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.452 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.452 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.452 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.452 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.452 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.452 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.452 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.452 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.452 | |
| 1c6y | MK1 | Protease | / | 0.451 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1m0b | 0ZQ | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.451 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.451 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.451 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.451 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.451 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.451 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.451 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.451 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.451 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 5dp2 | NAP | CurF | / | 0.451 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.450 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.450 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.450 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.450 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.450 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.450 | |
| 4m10 | ICD | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.450 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.450 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.449 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.449 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.449 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.449 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.449 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.449 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 3vvp | BNU | Uncharacterized protein | / | 0.449 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4rcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.449 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.448 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.448 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.448 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.448 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.448 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.448 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3so9 | 017 | Pol protein | / | 0.448 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.448 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.448 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.447 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.447 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.447 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.447 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.447 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.447 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.446 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.446 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.446 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.446 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.446 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.446 | |
| 1p0f | NAP | NADP-dependent alcohol dehydrogenase | 1.1.1.2 | 0.446 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.446 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.446 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.446 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.446 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.446 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.446 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.445 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.445 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.445 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.445 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.445 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.445 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.445 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.445 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.445 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.445 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.445 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.445 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.445 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.444 | |
| 1e79 | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.444 | |
| 1e79 | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.444 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.444 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1r2j | FAD | FkbI | / | 0.444 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.444 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.444 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.444 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.444 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.444 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.444 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.444 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.444 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.444 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.444 | |
| 3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.444 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.444 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.444 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.444 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.444 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.444 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.444 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.443 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.443 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2xy3 | DUP | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.443 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.443 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3e8x | NAP | BH1520 protein | / | 0.443 | |
| 3otf | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.443 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.443 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.443 | |
| 4irn | FAD | AnaB | / | 0.443 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.443 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.442 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.442 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.442 | |
| 2p3b | 3TL | V-1 protease | / | 0.442 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3ggo | NAI | Prephenate dehydrogenase | / | 0.442 | |
| 3i25 | MV7 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.442 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.442 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.442 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.442 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.442 | |
| 4xr9 | NAD | CalS8 | / | 0.442 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.441 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.441 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.441 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2gz8 | F3F | Orf1a polyprotein | / | 0.441 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2voj | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.441 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.441 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.441 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.441 | |
| 3oee | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.441 | |
| 3oee | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.441 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.441 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.441 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.441 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1 | / | 0.441 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1-binding protein 1 | / | 0.441 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.441 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4okn | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.441 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.440 | |
| 2c6t | DT5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.440 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.440 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.440 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.440 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.440 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.440 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.440 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.440 | |
| 4yqf | GDP | Septin-9 | / | 0.440 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.440 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.440 |