sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2hu2 | NAD | C-terminal binding protein 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2hu2 | NAD | C-terminal binding protein 1 | / | 1.000 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.610 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.537 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.518 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.485 | |
| 4nu5 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.481 | |
| 2dbz | NAP | Glyoxylate reductase | 1.1.1.26 | 0.463 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.462 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.462 | |
| 4e5m | NAP | Phosphonate dehydrogenase | 1.20.1.1 | 0.461 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.460 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.454 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.452 | |
| 4irn | FAD | AnaB | / | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.448 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.447 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.447 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.446 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.446 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.446 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.445 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.443 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.441 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.441 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.440 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.440 |