sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2hsa | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2hsa | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 1.000 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.548 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.531 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.526 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.524 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.523 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.522 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.519 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.517 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.516 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.516 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.515 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.513 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.511 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.510 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.508 | |
| 1lm1 | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.506 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.505 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.503 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.502 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.501 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.501 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.501 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.498 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.498 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.498 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.496 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.494 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.493 | |
| 3oix | FMN | Dihydroorotate dehydrogenase | / | 0.492 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.491 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.491 | |
| 2voj | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.491 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.491 | |
| 3nta | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.490 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.490 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.489 | |
| 2e8h | SAH | Diphthine synthase | / | 0.489 | |
| 4jic | FMN | GTN Reductase | / | 0.489 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.489 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.488 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.488 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.488 | |
| 1k02 | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.487 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.487 | |
| 4die | C5P | Cytidylate kinase | / | 0.487 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.486 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.486 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.486 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.486 | |
| 6req | 3CP | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.486 | |
| 2owg | SAH | Diphthine synthase | / | 0.485 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.485 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.485 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.484 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.484 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.483 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.483 | |
| 2oke | DUP | DUTP pyrophosphatase | / | 0.483 | |
| 2p6l | SAH | Diphthine synthase | / | 0.483 | |
| 3kc3 | MK2 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.483 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.483 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.482 | |
| 4e2b | FMN | Dehydrogenase | / | 0.482 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.482 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.481 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.481 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.480 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.480 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.480 | |
| 2e8r | SAH | Diphthine synthase | / | 0.479 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.479 | |
| 4uoc | NCN | CinA-like protein | / | 0.479 | |
| 2djl | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.478 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.478 | |
| 1r2j | FAD | FkbI | / | 0.477 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.477 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.477 | |
| 2y3p | SM8 | DNA gyrase subunit A | / | 0.477 | |
| 3b9l | AZZ | Serum albumin | / | 0.477 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.477 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.476 | |
| 1oyc | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.476 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.476 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.476 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.476 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.476 | |
| 2y4g | TIR | TamL | / | 0.475 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.475 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.474 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.474 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.474 | |
| 1ofe | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.474 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.474 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.474 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 2ejj | SAH | Diphthine synthase | / | 0.474 | |
| 2hut | SAH | Diphthine synthase | / | 0.474 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 3bm1 | FMN | Putative NAD(P)H nitroreductase YdjA | / | 0.474 | |
| 4e2d | FMN | Dehydrogenase | / | 0.474 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.474 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.473 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.473 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.473 | |
| 3ing | NDP | Homoserine dehydrogenase related protein | / | 0.473 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.473 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.473 | |
| 2huv | SAH | Diphthine synthase | / | 0.472 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.472 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.471 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.471 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.471 | |
| 2clm | F6F | Tryptophan synthase alpha chain | / | 0.471 | |
| 2egl | SAH | Diphthine synthase | / | 0.471 | |
| 2r5n | TPP | Transketolase 1 | / | 0.471 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.471 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.470 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 2el3 | SAH | Diphthine synthase | / | 0.470 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.470 | |
| 2xvw | 9NR | Serum albumin | / | 0.470 | |
| 3ms4 | 21N | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.470 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.470 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.470 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.470 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.470 | |
| 1ofd | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.469 | |
| 2bsl | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.469 | |
| 2dsi | SAH | Diphthine synthase | / | 0.469 | |
| 2e16 | SAH | Diphthine synthase | / | 0.469 | |
| 2hux | SAH | Diphthine synthase | / | 0.469 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.469 | |
| 2owk | SAH | Diphthine synthase | / | 0.469 | |
| 2owu | SAH | Diphthine synthase | / | 0.469 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.469 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.469 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.469 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.469 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.469 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.468 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.468 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.468 | |
| 2p2b | PRX | Acetyl-coenzyme A synthetase | / | 0.468 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.468 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.468 | |
| 4yer | ADP | Antibiotic ABC transporter, ATP-binding protein, putative | / | 0.468 | |
| 1llw | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.467 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.467 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.467 | |
| 2eeq | SAH | Diphthine synthase | / | 0.467 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4hh4 | SAH | CcbJ | / | 0.467 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.467 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.467 | |
| 4x3m | ADN | RNA 2'-O ribose methyltransferase | / | 0.467 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 2emu | SAH | Diphthine synthase | / | 0.466 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.466 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.466 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.466 | |
| 5cnn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.466 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 2dsh | SAH | Diphthine synthase | / | 0.465 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.465 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.465 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.465 | |
| 3ih0 | ANP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.465 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.465 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.465 | |
| 4b5d | SW4 | Achbp | / | 0.465 | |
| 5a3c | NAD | SIR2 family protein | / | 0.465 | |
| 1llz | FMN | Ferredoxin-dependent glutamate synthase 2 | 1.4.7.1 | 0.464 | |
| 2dek | SAH | Diphthine synthase | / | 0.464 | |
| 2dxv | SAH | Diphthine synthase | / | 0.464 | |
| 2e15 | SAH | Diphthine synthase | / | 0.464 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.464 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.464 | |
| 2owv | SAH | Diphthine synthase | / | 0.464 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.464 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.464 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.464 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.464 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.464 | |
| 4y0k | NAP | AntE | / | 0.464 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.464 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 1f0y | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.463 | |
| 2djx | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.463 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.463 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.463 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.463 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.463 | |
| 2p5c | SAH | Diphthine synthase | / | 0.463 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 2pch | SAH | Diphthine synthase | / | 0.463 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.463 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.463 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.463 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.463 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.463 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.463 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.462 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.462 | |
| 1l8a | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.462 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.462 | |
| 1wng | SAH | Diphthine synthase | / | 0.462 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.462 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.462 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.462 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.462 | |
| 2p5f | SAH | Diphthine synthase | / | 0.462 | |
| 2pca | SAH | Diphthine synthase | / | 0.462 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 3rqq | BA3 | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.462 | |
| 3vmm | P0D | Alanine--anticapsin ligase | / | 0.462 | |
| 4loy | 6XS | Prothrombin | 3.4.21.5 | 0.462 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.462 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.462 | |
| 5fm6 | ADP | RuvB-like helicase | / | 0.462 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.461 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.461 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.461 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.461 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.461 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.461 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.461 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.461 | |
| 3zcs | CAW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.461 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.461 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.461 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.460 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.460 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.460 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.460 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.460 | |
| 2eld | SAH | Diphthine synthase | / | 0.460 | |
| 2emr | SAH | Diphthine synthase | / | 0.460 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.460 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.460 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3g2h | KOT | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.460 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.460 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.460 | |
| 4e2w | JHZ | Methyltransferase | / | 0.460 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.460 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.460 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.459 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.459 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.459 | |
| 2br5 | SAH | Cephalosporin hydroxylase CmcI | / | 0.459 | |
| 2p6i | SAH | Diphthine synthase | / | 0.459 | |
| 3eku | CY9 | Actin-5C | / | 0.459 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.459 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3nyc | FAD | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.459 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.459 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.459 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.459 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.459 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.459 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.459 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.458 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.458 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.458 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.458 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.458 | |
| 2egb | SAH | Diphthine synthase | / | 0.458 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.458 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.458 | |
| 2r6g | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.458 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.458 | |
| 2z6c | FMN | Phototropin-1 | 2.7.11.1 | 0.458 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.458 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.458 | |
| 4fuj | 1U9 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.458 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.458 | |
| 4h3z | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.458 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.458 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.458 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.457 | |
| 1gil | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.457 | |
| 1kqc | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.457 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.457 | |
| 2dsg | SAH | Diphthine synthase | / | 0.457 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.457 | |
| 2egs | SAH | Diphthine synthase | / | 0.457 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 2qdx | FAD | Ferredoxin--NADP+ reductase | / | 0.457 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 2vhv | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.457 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.457 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.457 | |
| 3gye | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.457 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.457 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.457 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.456 | |
| 2ejk | SAH | Diphthine synthase | / | 0.456 | |
| 2gfd | RDA | Endoplasmin | / | 0.456 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.456 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.456 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.456 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 3w23 | 3RO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.456 | |
| 3wfj | NAD | 2-dehydropantoate 2-reductase | / | 0.456 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.456 | |
| 3zhy | FM6 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.456 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.456 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.456 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.455 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.455 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.455 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.455 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.455 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.455 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.455 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.455 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.455 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.455 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.455 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.455 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.455 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.455 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.455 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.455 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.455 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.455 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.455 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.455 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.454 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.454 | |
| 1m75 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.454 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.454 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.454 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 2v00 | V15 | Endothiapepsin | 3.4.23.22 | 0.454 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.454 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.454 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2xvv | 9DN | Serum albumin | / | 0.454 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.454 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.454 | |
| 3g2l | LEW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.454 | |
| 3rdq | DTB | Streptavidin | / | 0.454 | |
| 4hhd | FMN | Phototropin-1 | 2.7.11.1 | 0.454 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.454 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.454 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.454 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.454 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.454 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.453 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.453 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.453 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.453 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.453 | |
| 2dxx | SAH | Diphthine synthase | / | 0.453 | |
| 2eka | SAH | Diphthine synthase | / | 0.453 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.453 | |
| 2q3e | NAI | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.453 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.453 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.453 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.453 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3suf | SUE | Polyprotein | / | 0.453 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.453 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.453 | |
| 4y38 | 0A9 | Endothiapepsin | 3.4.23.22 | 0.453 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.452 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.452 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.452 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.452 | |
| 1g41 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.452 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.452 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1t0i | FMN | NAD(P)H-dependent FMN reductase LOT6 | / | 0.452 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.452 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.452 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.452 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.452 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.452 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.452 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.452 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3pgi | F41 | Endothiapepsin | 3.4.23.22 | 0.452 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.452 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.452 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.452 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.452 | |
| 4u0m | ATP | Cyclic GMP-AMP synthase | / | 0.452 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.451 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
| 1qf5 | RPL | Adenylosuccinate synthetase | / | 0.451 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.451 | |
| 1uay | ADN | Oxidoreductase | / | 0.451 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.451 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.451 | |
| 2eud | GCQ | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.451 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.451 | |
| 2fto | TMP | Thymidylate synthase | / | 0.451 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.451 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.451 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2yy8 | SAM | tRNA (cytidine(56)-2'-O)-methyltransferase | / | 0.451 | |
| 2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.451 | |
| 2zfa | FMN | Lactate oxidase | / | 0.451 | |
| 3c3n | FMN | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.451 | |
| 3eo8 | FMN | Putative nitroreductase | / | 0.451 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.451 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.451 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.451 | |
| 3vqh | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 4b45 | GSP | Tubulin-like protein CetZ2 | / | 0.451 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 4ihl | 1F5 | 14-3-3 protein zeta/delta | / | 0.451 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.451 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.451 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.451 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.451 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.450 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.450 | |
| 1gox | FMN | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.450 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.450 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.450 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.450 | |
| 2g94 | ZPQ | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.450 | |
| 2pck | SAH | Diphthine synthase | / | 0.450 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.450 | |
| 2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.450 | |
| 3lxp | IZA | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.450 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.450 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.450 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.450 | |
| 4axa | RKD | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.450 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.450 | |
| 4u7w | NDP | MxaA | / | 0.450 | |
| 4x9m | FAD | Uncharacterized protein MG039 homolog | / | 0.450 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.450 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 5hxw | FAD | L-amino acid deaminase | / | 0.450 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.449 | |
| 1gia | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.449 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.449 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.449 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.449 | |
| 1w51 | L01 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.449 | |
| 2ci0 | 1CM | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.449 | |
| 2e07 | SAH | Diphthine synthase | / | 0.449 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.449 | |
| 2ele | SAH | Diphthine synthase | / | 0.449 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.449 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.449 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.449 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.449 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.449 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.449 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.449 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.449 | |
| 3gon | ANP | Phosphomevalonate kinase | / | 0.449 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.449 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.449 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.449 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 3tos | SAH | CalS11 | / | 0.449 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4e07 | ACP | Plasmid partitioning protein ParF | / | 0.449 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.449 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.449 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4kuo | RBF | Putative blue-light photoreceptor | / | 0.449 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4xr9 | NAD | CalS8 | / | 0.449 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.449 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.449 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.449 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.448 | |
| 1g2a | BB2 | Peptide deformylase | 3.5.1.88 | 0.448 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.448 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.448 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.448 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.448 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.448 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.448 | |
| 3qe0 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.448 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.448 | |
| 4egh | 0OY | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.448 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 4fkl | CK2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4q4k | FMN | Uncharacterized protein | / | 0.448 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.448 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.448 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.448 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.448 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.448 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.447 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 1f28 | UMP | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.447 | |
| 1iqr | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.447 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.447 | |
| 1p0f | NAP | NADP-dependent alcohol dehydrogenase | 1.1.1.2 | 0.447 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.447 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.447 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.447 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.447 | |
| 2dxw | SAH | Diphthine synthase | / | 0.447 | |
| 2el0 | SAH | Diphthine synthase | / | 0.447 | |
| 2en5 | SAH | Diphthine synthase | / | 0.447 | |
| 2eni | SAH | Diphthine synthase | / | 0.447 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.447 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.447 | |
| 2nvb | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.447 | |
| 2oz0 | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.447 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.447 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2vf7 | ADP | UvrABC system protein A | / | 0.447 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.447 | |
| 2y3r | TRK | TamL | / | 0.447 | |
| 2yye | APC | Selenide, water dikinase | 2.7.9.3 | 0.447 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.447 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.447 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 3qwp | SAM | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.447 | |
| 3r96 | ACO | MccE protein | / | 0.447 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.447 | |
| 3ru0 | SFG | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.447 | |
| 3zkd | ANP | DNA gyrase subunit B | / | 0.447 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4qxr | 1YE | Stimulator of interferon genes protein | / | 0.447 | |
| 1cjv | DAD | Adenylate cyclase type 2 | / | 0.446 | |
| 1cjv | DAD | Adenylate cyclase type 5 | / | 0.446 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.446 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.446 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.446 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.446 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.446 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.446 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.446 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.446 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.446 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.446 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.446 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.446 | |
| 3elc | F01 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.446 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.446 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.446 | |
| 3rq6 | APR | ADP-dependent (S)-NAD(P)H-hydrate dehydratase | / | 0.446 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 3t8v | BTJ | M1 family aminopeptidase | 3.4.11 | 0.446 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.446 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.446 | |
| 3w3o | ROE | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.446 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.446 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.446 | |
| 4c59 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.446 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.446 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.446 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.446 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.446 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.446 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.446 | |
| 4wzh | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.446 | |
| 4yvj | SFG | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.446 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.446 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1ea0 | FMN | Glutamate synthase [NADPH] large chain | 1.4.1.13 | 0.445 | |
| 1j3k | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.445 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.445 | |
| 1n9l | FMN | Putative blue light receptor | / | 0.445 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.445 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.445 | |
| 1vce | SAH | Diphthine synthase | / | 0.445 | |
| 1vea | HBN | Hut operon positive regulatory protein | / | 0.445 | |
| 1yre | COA | Uncharacterized protein | / | 0.445 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.445 | |
| 1zap | A70 | Candidapepsin-2 | 3.4.23.24 | 0.445 | |
| 2gbl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.445 | |
| 2tys | PLT | Tryptophan synthase beta chain | 4.2.1.20 | 0.445 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.445 | |
| 3aeb | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.445 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.445 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.445 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.445 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.445 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.445 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.445 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3pbz | F02 | Endothiapepsin | 3.4.23.22 | 0.445 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.445 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3x2w | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 3zkb | ANP | DNA gyrase subunit B | / | 0.445 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4clo | NAP | Pteridine reductase | / | 0.445 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 4de1 | 0J6 | Beta-lactamase | / | 0.445 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.445 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.445 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.445 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.445 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.445 | |
| 4k5o | 1OT | M1 family aminopeptidase | 3.4.11 | 0.445 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.445 | |
| 4kwh | NAP | Reductase homolog | / | 0.445 | |
| 4mub | OAQ | Sulfotransferase oxamniquine resistance protein | / | 0.445 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.445 | |
| 4xbo | SAH | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.1.1.200 | 0.445 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.445 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.445 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.444 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.444 | |
| 1k08 | BZD | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.444 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.444 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.444 | |
| 1ykg | FMN | Sulfite reductase [NADPH] flavoprotein alpha-component | / | 0.444 | |
| 1z48 | FMN | NADPH dehydrogenase | / | 0.444 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.444 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.444 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 2pcm | SAH | Diphthine synthase | / | 0.444 | |
| 2pe0 | 39Z | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.444 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.444 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 2wf0 | ZY0 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.444 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 3e8x | NAP | BH1520 protein | / | 0.444 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.444 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.444 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3zly | YSO | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.444 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.444 | |
| 4bmp | FMN | Protein NrdI | / | 0.444 | |
| 4co4 | ATP | Nitrogen regulatory protein P-II 1 | / | 0.444 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.444 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.444 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4h3y | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.444 | |
| 4l16 | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.444 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.444 | |
| 4r38 | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.444 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.444 | |
| 5ftc | ADP | TPR domain protein | / | 0.444 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.444 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.443 | |
| 1coz | CTP | Glycerol-3-phosphate cytidylyltransferase | 2.7.7.39 | 0.443 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1gqt | ACP | Ribokinase | / | 0.443 | |
| 1h2h | NAD | L-aspartate dehydrogenase | 1.4.1.21 | 0.443 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.443 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.443 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1w5s | ADP | ORC1-type DNA replication protein 2 | / | 0.443 | |
| 1wvg | APR | CDP-glucose 4,6-dehydratase | 4.2.1.45 | 0.443 | |
| 1yjq | NAP | 2-dehydropantoate 2-reductase | 1.1.1.169 | 0.443 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.443 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.443 | |
| 2cmo | M1L | Glutamate receptor 2 | / | 0.443 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 3bbd | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | 2.1.1 | 0.443 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.443 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.443 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.443 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.443 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.443 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.443 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.443 | |
| 5cno | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.443 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.443 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.442 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 1ez0 | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.442 | |
| 1g28 | FMN | PHY3 | / | 0.442 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.442 | |
| 1i2c | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.442 | |
| 1m76 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1s16 | ANP | DNA topoisomerase 4 subunit B | / | 0.442 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.442 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.442 | |
| 2e17 | SAH | Diphthine synthase | / | 0.442 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.442 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.442 | |
| 2gde | SN3 | Prothrombin | 3.4.21.5 | 0.442 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.442 | |
| 2jiz | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 2nv4 | SAM | S-adenosyl-L-methionine-binding protein AF_0241 | / | 0.442 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.442 | |
| 2p9d | SAH | Diphthine synthase | / | 0.442 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.442 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 2z6r | SAH | Diphthine synthase | / | 0.442 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.442 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.442 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.442 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.442 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.442 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.442 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.442 | |
| 3prs | RIT | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 3qw4 | U5P | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | / | 0.442 | |
| 3r95 | ACO | MccE protein | / | 0.442 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.442 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.442 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.442 | |
| 3w8r | ACP | Uridine kinase | / | 0.442 | |
| 4a7b | 3W5 | Collagenase 3 | 3.4.24 | 0.442 | |
| 4hdh | ATP | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.442 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.442 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.441 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.441 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1g0r | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.441 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.441 | |
| 1j7k | ATP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.441 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 1njf | ADP | DNA polymerase III subunit tau | 2.7.7.7 | 0.441 | |
| 1p4a | PCP | Pur operon repressor | / | 0.441 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.441 | |
| 2ax4 | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 2.7.1.25 | 0.441 | |
| 2e08 | SAH | Diphthine synthase | / | 0.441 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.441 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.441 | |
| 2huq | SAH | Diphthine synthase | / | 0.441 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.441 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.441 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2ji6 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.441 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.441 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.441 | |
| 2qir | COA | Aminoglycoside 6-N-acetyltransferase type Ib11 | / | 0.441 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.441 | |
| 2y3s | TIR | TamL | / | 0.441 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.441 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.441 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.441 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 3gol | XND | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3koz | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.441 | |
| 3m42 | HGF | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.441 | |
| 3u7l | UDB | Peptide deformylase | / | 0.441 | |
| 3w1q | YRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.441 | |
| 3zxz | KRW | Hepatocyte growth factor receptor | 2.7.10.1 | 0.441 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.441 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.441 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.441 | |
| 4kgn | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.441 | |
| 4m69 | ANP | Receptor-interacting serine/threonine-protein kinase 3 | 2.7.11.1 | 0.441 | |
| 4mcd | 22L | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.441 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.441 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.441 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.441 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.440 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.440 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.440 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.440 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.440 | |
| 1n7h | GDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.440 | |
| 1rp7 | TZD | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.440 | |
| 1rz1 | NAD | Phenol 2-hydroxylase component B | / | 0.440 | |
| 1y8y | CT7 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2ejz | SAH | Diphthine synthase | / | 0.440 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.440 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.440 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.440 | |
| 2i7n | ACO | Pantothenate kinase 1 | 2.7.1.33 | 0.440 | |
| 2iyi | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.440 | |
| 2ph8 | 35A | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.440 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2w14 | WR2 | Snake venom metalloproteinase BaP1 | 3.4.24 | 0.440 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2xw1 | 9NV | Serum albumin | / | 0.440 | |
| 2ydx | STL | Methionine adenosyltransferase 2 subunit beta | / | 0.440 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.440 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.440 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.440 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.440 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.440 | |
| 3iob | A4D | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 3o15 | IFP | Thiamine-phosphate synthase | / | 0.440 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.440 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.440 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.440 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.440 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.440 | |
| 4eiq | KCT | Putative FAD-monooxygenase | / | 0.440 | |
| 4fuf | 8UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.440 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4uyg | 73B | Bromodomain-containing protein 2 | / | 0.440 | |
| 4z9r | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.440 | |
| 5dmh | ADP | 3-oxo-tetronate kinase | / | 0.440 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.440 |