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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2hnzPC0Gag-Pol polyprotein2.7.7.49

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2hnzPC0Gag-Pol polyprotein2.7.7.491.000
1tl3H20Gag-Pol polyprotein2.7.7.490.601
1tktH12Gag-Pol polyprotein2.7.7.490.581
3qlhT27Gag-Pol polyprotein2.7.7.490.557
3m8qDJZGag-Pol polyprotein2.7.7.490.551
1rt4UC1Gag-Pol polyprotein2.7.7.490.548
3is9AC7Gag-Pol polyprotein2.7.7.490.548
1jlcFTCGag-Pol polyprotein2.7.7.490.545
1tkzH16Gag-Pol polyprotein2.7.7.490.545
3nbpJGZGag-Pol polyprotein2.7.7.490.545
3megT27Gag-Pol polyprotein2.7.7.490.544
3m8p65BGag-Pol polyprotein2.7.7.490.542
4g1qT27Gag-Pol polyprotein2.7.7.490.536
4i2pG73Gag-Pol polyprotein2.7.7.490.536
4ifvT27Gag-Pol polyprotein2.7.7.490.536
1vruAAPGag-Pol polyprotein2.7.7.490.534
2zd1T27Gag-Pol polyprotein2.7.7.490.529
3irxUDRGag-Pol polyprotein2.7.7.490.529
3med65BGag-Pol polyprotein2.7.7.490.528
2ze2T27Gag-Pol polyprotein2.7.7.490.526
4id5T27Gag-Pol polyprotein2.7.7.490.524
3mec65BGag-Pol polyprotein2.7.7.490.523
1hnvTBOGag-Pol polyprotein2.7.7.490.522
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.522
1revTB9Gag-Pol polyprotein2.7.7.490.519
4i2q1BTGag-Pol polyprotein2.7.7.490.519
1rt5UC2Gag-Pol polyprotein2.7.7.490.511
1hpzAAPGag-Pol polyprotein2.7.7.490.510
1s6qTPBGag-Pol polyprotein2.7.7.490.510
1s9eADBGag-Pol polyprotein2.7.7.490.510
1c1bGCAGag-Pol polyprotein2.7.7.490.509
1fk9EFZGag-Pol polyprotein2.7.7.490.509
1osvCHCBile acid receptor/0.509
3ffi3OBGag-Pol polyprotein2.7.7.490.509
4kko1REGag-Pol polyprotein2.7.7.490.508
1ikyMSDGag-Pol polyprotein2.7.7.490.507
3meeT27Gag-Pol polyprotein2.7.7.490.507
1ikvEFZGag-Pol polyprotein2.7.7.490.503
1rt7UC4Gag-Pol polyprotein2.7.7.490.503
3i0rRT3Gag-Pol polyprotein2.7.7.490.503
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.501
1eetBFUGag-Pol polyprotein2.7.7.490.500
4ko0JLJGag-Pol polyprotein2.7.7.490.500
3t8xT8XT-cell surface glycoprotein CD1b/0.499
4a83DXCMajor pollen allergen Bet v 1-A/0.498
1ikwEFZGag-Pol polyprotein2.7.7.490.497
2vg7NNIGag-Pol polyprotein2.7.7.490.497
1tl1H18Gag-Pol polyprotein2.7.7.490.496
4j6cSTRCytochrome P450 monooxygenase/0.496
1dkfBMSRetinoic acid receptor alpha/0.494
1tvrTB9Gag-Pol polyprotein2.7.7.490.493
1jlgUC1Gag-Pol polyprotein2.7.7.490.492
3lanKBTGag-Pol polyprotein2.7.7.490.491
3vt8YI3Vitamin D3 receptor/0.491
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.491
2vzmNRBCytochrome P450 monooxygenase PikC/0.490
2dqsTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.489
1lriCLRBeta-elicitin cryptogein/0.488
3lu8IQXSerum albumin/0.487
1zhzERGOxysterol-binding protein homolog 4/0.486
3bejMUFBile acid receptor/0.486
1s1wUC1Gag-Pol polyprotein2.7.7.490.485
2y03Y01Beta-1 adrenergic receptor/0.485
3bfa9ODOdorant binding protein ASP1/0.485
1ezvSMACytochrome b/0.484
1zhwHC2Oxysterol-binding protein homolog 4/0.484
2ban357Gag-Pol polyprotein2.7.7.490.484
2jn3JN3Fatty acid-binding protein, liver/0.484
4nb6444Nuclear receptor ROR-gamma/0.484
5iua6DXAdenosine receptor A2a/0.484
2c7xNRBCytochrome P450 monooxygenase PikC/0.483
1kb9SMACytochrome b/0.482
2z3uCRRCytochrome P450/0.482
4xwtU5PRibonuclease J/0.482
1tkxGWBGag-Pol polyprotein2.7.7.490.481
2vg5NNCGag-Pol polyprotein2.7.7.490.481
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.481
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.481
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.480
1ot7CHCBile acid receptor/0.479
3abaFLICytochrome P450/0.479
1rt2TNKGag-Pol polyprotein2.7.7.490.478
4kfp1R7Nicotinamide phosphoribosyltransferase2.4.2.120.478
4la0198Serum albumin/0.478
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.477
3vt9YI4Vitamin D3 receptor/0.477
1o5rFR9Adenosine deaminase3.5.4.40.476
3p6oETGCamphor 5-monooxygenase1.14.15.10.476
5k2aZMAAdenosine receptor A2a/0.476
1n4hREANuclear receptor ROR-beta/0.475
2rf2MRXGag-Pol polyprotein2.7.7.490.475
4ig3T27Gag-Pol polyprotein2.7.7.490.475
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.474
4j6bPLOCytochrome P450 monooxygenase/0.474
2w4qCBWProstaglandin reductase 21.3.1.480.473
3p99LNPLanosterol 14-alpha-demethylase/0.473
5k2bZMAAdenosine receptor A2a/0.473
4a81DXCMajor pollen allergen Bet v 1-A/0.472
5jtbZMAAdenosine receptor A2a/0.472
4uhrNGIAdenosine receptor A2a/0.472
4z9g1Q5Corticotropin-releasing factor receptor 1/0.472
1l2jETCEstrogen receptor beta/0.471
1rdtL79Retinoic acid receptor RXR-alpha/0.471
3bfb9ODPheromone-binding protein ASP1/0.471
3gc9B45Mitogen-activated protein kinase 112.7.11.240.471
3r9dX6BCyclin-dependent kinase 22.7.11.220.471
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.471
4jvlESTEstrogen sulfotransferase2.8.2.40.471
1kk4ACOStreptogramin A acetyltransferase2.3.10.470
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.470
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.470
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.470
4pkl1GHUncharacterized protein/0.470
1qxlFR8Adenosine deaminase3.5.4.40.469
2om9AJAPeroxisome proliferator-activated receptor gamma/0.469
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.469
4bb3KKAIsopenicillin N synthase1.21.3.10.469
4othDRNSerine/threonine-protein kinase N1/0.469
1hniAAAGag-Pol polyprotein2.7.7.490.468
1ikxPNUGag-Pol polyprotein2.7.7.490.468
1kt3RTLRetinol-binding protein 4/0.468
1ppjANYCytochrome b/0.468
2r3yVAL_TYR_TRP_PHESerine endoprotease DegS3.4.21.1070.468
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.468
1bk0ACVIsopenicillin N synthase1.21.3.10.467
1e7aPFLSerum albumin/0.467
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
2aibERGBeta-elicitin cinnamomin/0.467
2zjwREFCasein kinase II subunit alpha2.7.11.10.467
3wmxNADNAD dependent epimerase/dehydratase/0.467
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
4o701QKBromodomain-containing protein 4/0.467
5k2dZMAAdenosine receptor A2a/0.467
1wrlTFPTroponin C, slow skeletal and cardiac muscles/0.466
3a1l2CCCytochrome P450/0.466
3hz5Z64Heat shock protein HSP 90-alpha/0.466
3kpkFADSulfide-quinone reductase/0.466
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.466
4h380YXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.466
4jazSTLPeroxisome proliferator-activated receptor gamma/0.466
4rw6494Gag-Pol polyprotein2.7.7.490.466
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.465
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.465
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.465
3dxjNE6DNA-directed RNA polymerase subunit beta/0.465
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.465
3nalDBKCalcium-transporting ATPase/0.465
3p6nDSOCamphor 5-monooxygenase1.14.15.10.465
4jlj1NMDeoxycytidine kinase2.7.1.740.465
1iyzNDPProbable quinone oxidoreductase/0.464
1tduCB3Thymidylate synthase/0.464
2c3qGTXGlutathione S-transferase theta-12.5.1.180.464
3dolGWIPol protein/0.464
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
4iarERM5-hydroxytryptamine receptor 1B/0.464
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.464
3reyXACAdenosine receptor A2a/0.464
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.463
1s1tUC1Gag-Pol polyprotein2.7.7.490.463
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.463
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.463
3dhoB2MStreptogramin A acetyltransferase2.3.10.463
3g70A5TRenin3.4.23.150.463
3lamKRPGag-Pol polyprotein2.7.7.490.463
3vt5YI2Vitamin D3 receptor/0.463
4jbtASDCytochrome P450 monooxygenase/0.463
4kwi1TJReductase homolog/0.463
4ocvANPAminoglycoside phosphotransferase/0.463
5uviZMAAdenosine receptor A2a/0.463
1sejF89Bifunctional dihydrofolate reductase-thymidylate synthase/0.462
1v7aFRCAdenosine deaminase3.5.4.40.462
2w0bCMWLanosterol 14-alpha demethylase1.14.13.700.462
3jw3TOPDihydrofolate reductase/0.462
3stv3HOMethylketone synthase I/0.462
3vewADPnebramycin 5' synthase6.1.2.20.462
4cnjFADL-amino acid oxidase/0.462
4g1z0VPVitamin D3 receptor A/0.462
4i3vNADAldehyde dehydrogenase (NAD+)/0.462
4kfbT27Gag-Pol polyprotein2.7.7.490.462
4mlhVO2Glucokinase2.7.1.20.462
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.462
3emlZMAAdenosine receptor A2a/0.462
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.461
1rf9DBRCamphor 5-monooxygenase1.14.15.10.461
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.461
2opqHBQGag-Pol polyprotein2.7.7.490.461
2vn0TDZCytochrome P450 2C8/0.461
3vtdTKDVitamin D3 receptor/0.461
4b7sQLECytochrome P450 monooxygenase PikC/0.461
5hs1VORLanosterol 14-alpha demethylase/0.461
1xuoLA1Integrin alpha-L/0.460
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
2vf0F89Thymidylate synthase/0.460
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.460
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.460
3kpzZNEVitamin D3 receptor/0.460
4jvmXDIEstrogen sulfotransferase2.8.2.40.460
2hcdBIVVitamin D3 receptor A/0.459
2yee2ECHeat shock protein HSP 90-alpha/0.459
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
3cseN22Uncharacterized protein/0.459
3dl9V2HVitamin D 25-hydroxylase/0.459
3dleGFAGag-Pol polyprotein2.7.7.490.459
3p6pA6BCamphor 5-monooxygenase1.14.15.10.459
3p9tTCLRepressor/0.459
3qppPFWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
3sgtP09Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)/0.459
3srrQ20Dihydrofolate reductase1.5.1.30.459
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.459
4qe6JN3Bile acid receptor/0.459
5k2cZMAAdenosine receptor A2a/0.459
1errRALEstrogen receptor/0.458
1hvyD16Thymidylate synthase2.1.1.450.458
1zeoC01Peroxisome proliferator-activated receptor gamma/0.458
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
2ibzSMACytochrome b/0.458
2ie0ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
3vspEK8Peroxisome proliferator-activated receptor gamma/0.458
4g210VPVitamin D3 receptor A/0.458
5cyqT27Gag-Pol polyprotein2.7.7.490.458
1kzjCB3Thymidylate synthase/0.457
1ndeMONEstrogen receptor beta/0.457
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.457
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.457
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.457
2hw2RFPRifampin ADP-ribosyl transferase/0.457
2jfgUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.457
3fr0AJBGlucokinase2.7.1.20.457
3h1jSMACytochrome b/0.457
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4b1fKRHGlutamate racemase/0.457
4cd2FOLDihydrofolate reductase1.5.1.30.457
4j6dTESCytochrome P450 monooxygenase/0.457
4qi5FADCellobiose dehydrogenase/0.457
1n83CLRNuclear receptor ROR-alpha/0.456
1r6g442Thyroid hormone receptor beta/0.456
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
2po7CHDFerrochelatase, mitochondrial4.99.1.10.456
2uxoTACHTH-type transcriptional regulator TtgR/0.456
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.456
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
3vt7VDXVitamin D3 receptor/0.456
3zk5Z18Cytochrome P450 monooxygenase PikC/0.456
4ejgNCTCytochrome P450 2A131.14.14.10.456
4ele31IDihydrofolate reductase/0.456
4fhi0S4Vitamin D3 receptor A/0.456
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.456
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.456
4okt198Androgen receptor/0.456
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.455
1ie9VDXVitamin D3 receptor/0.455
1kqwRTLCellular retinol-binding protein type II/0.455
1ndzFR5Adenosine deaminase3.5.4.40.455
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.455
2fzhDH1Dihydrofolate reductase1.5.1.30.455
2xytTC9Soluble acetylcholine receptor/0.455
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.455
3oom507Activin receptor type-12.7.11.300.455
3ua506XCytochrome P450 2B61.14.130.455
4ejh0QACytochrome P450 2A131.14.14.10.455
4ez72ANCyclin-dependent kinase 22.7.11.220.455
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.455
4qa1B3NHistone deacetylase 83.5.1.980.455
5dq8FLFTranscriptional enhancer factor TEF-4/0.455
1cbrREACellular retinoic acid-binding protein 1/0.454
1cc2FADCholesterol oxidase1.1.3.60.454
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.454
1re9DSOCamphor 5-monooxygenase1.14.15.10.454
2fszOHTEstrogen receptor beta/0.454
2wpwACOOrf14/0.454
2ydoADNAdenosine receptor A2a/0.454
2yneNHWGlycylpeptide N-tetradecanoyltransferase/0.454
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.454
3cd2MTXDihydrofolate reductase1.5.1.30.454
3ce31FNHepatocyte growth factor receptor2.7.10.10.454
3cxhSMACytochrome b/0.454
3g6zA7TRenin3.4.23.150.454
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.454
3w0aDS5Vitamin D3 receptor/0.454
3w0yDS4Vitamin D3 receptor/0.454
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.454
4a28ADPKinesin-like protein KIF11/0.454
4b7dQLECytochrome P450 monooxygenase PikC/0.454
5a27MYAGlycylpeptide N-tetradecanoyltransferase/0.454
4zj8SUVOrexin receptor type 1/0.454
1fbyREARetinoic acid receptor RXR-alpha/0.453
1wxyFRKAdenosine deaminase3.5.4.40.453
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.453
2hb7O1CVitamin D3 receptor/0.453
3a9wNADNDP-sugar epimerase/0.453
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3gfbNADL-threonine 3-dehydrogenase/0.453
3i0sRT7Gag-Pol polyprotein2.7.7.490.453
3iaeD7KBenzaldehyde lyase/0.453
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
3stxBKAMethylketone synthase I/0.453
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.453
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.453
3vf2ADPnebramycin 5' synthase6.1.2.20.453
3vrwYS5Vitamin D3 receptor/0.453
3vt65YIVitamin D3 receptor/0.453
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.453
5dc5B3NHistone deacetylase 83.5.1.980.453
1ek2CDUBifunctional epoxide hydrolase 2/0.452
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.452
2w3vTOPDihydrofolate reductase/0.452
3h0a9RARetinoic acid receptor RXR-alpha/0.452
3kytHC2Nuclear receptor ROR-gamma/0.452
4ez8DHFThymidylate synthase2.1.1.450.452
4fhh0U3Vitamin D3 receptor A/0.452
4jx1CAMCamphor 5-monooxygenase1.14.15.10.452
4ubsDIFPentalenic acid synthase1.14.15.110.452
1m52P17Tyrosine-protein kinase ABL12.7.10.20.451
1nq7ARLNuclear receptor ROR-beta/0.451
2harOCCVitamin D3 receptor/0.451
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
2qe4JJ3Estrogen receptor/0.451
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.451
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.451
3p3zP3ZPutative cytochrome P450/0.451
3vtcTK3Vitamin D3 receptor/0.451
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4g1y0VOVitamin D3 receptor A/0.451
4ib4ERM5-hydroxytryptamine receptor 2B/0.451
4lb2DM5Serum albumin/0.451
4lva20MNicotinamide phosphoribosyltransferase2.4.2.120.451
1rkhVD2Vitamin D3 receptor/0.450
1x8lOXRRetinol dehydratase/0.450
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
2o4rVD5Vitamin D3 receptor/0.450
3gbk2PQPeroxisome proliferator-activated receptor gamma/0.450
3hazFADBifunctional protein PutA/0.450
3icsCOACoenzyme A disulfide reductase/0.450
3ictCOACoenzyme A disulfide reductase/0.450
3inwJZBHeat shock protein HSP 90-alpha/0.450
3zkyWT4Isopenicillin N synthase1.21.3.10.450
4dsbA8SAbscisic acid receptor PYL3/0.450
4e37NDPCatalase1.11.1.60.450
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.450
4ku5DCC3-oxoacyl-[ACP] synthase III/0.450
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
2cduFADNADH oxidase/0.449
3d78NBBPheromone-binding protein ASP1/0.449
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
3iw8HIZMitogen-activated protein kinase 14/0.449
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
3qlxQLRUncharacterized protein/0.449
3tnlNADShikimate dehydrogenase (NADP(+))/0.449
4iaq2GM5-hydroxytryptamine receptor 1B/0.449
1chwHXCChalcone synthase 22.3.1.740.448
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.448
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.448
1m13HYFNuclear receptor subfamily 1 group I member 2/0.448
1uydPU8Heat shock protein HSP 90-alpha/0.448
1xddAAYIntegrin alpha-L/0.448
1yqj6NPMitogen-activated protein kinase 14/0.448
1ysx4EBSerum albumin/0.448
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.448
2fvdLIACyclin-dependent kinase 22.7.11.220.448
2iviACWIsopenicillin N synthase1.21.3.10.448
2p15EZTEstrogen receptor/0.448
2wpxACOOrf14/0.448
3bgrT27Gag-Pol polyprotein2.7.7.490.448
3fl8RARDihydrofolate reductase/0.448
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3l0lHC3Nuclear receptor ROR-gamma/0.448
3lu6IMXSerum albumin/0.448
3ol5SAWCamphor 5-monooxygenase1.14.15.10.448
3p6mDSOCamphor 5-monooxygenase1.14.15.10.448
3rpnGTXGlutathione S-transferase kappa 12.5.1.180.448
3sfi3SFHTH-type transcriptional regulator EthR/0.448
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.448
3t2yFADSulfide-quinone reductase/0.448
3zoiM2WIsopenicillin N synthase1.21.3.10.448
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.448
4i6gFADCryptochrome-2/0.448
4ia1BIVVitamin D3 receptor A/0.448
4iui1GQEstrogen receptor/0.448
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.448
5g53NECAdenosine receptor A2a/0.448
1f4gTP4Thymidylate synthase/0.447
1hb1OCVIsopenicillin N synthase1.21.3.10.447
1hquHBYGag-Pol polyprotein2.7.7.490.447
1jlaTNKGag-Pol polyprotein2.7.7.490.447
1kt6RTLRetinol-binding protein 4/0.447
1ot7IU5Bile acid receptor/0.447
1wsvTHHAminomethyltransferase, mitochondrial/0.447
2e9cB75Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.447
2j0vGDPRac-like GTP-binding protein ARAC7/0.447
2jb4A14Isopenicillin N synthase1.21.3.10.447
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.447
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.447
3fnu006HAP protein/0.447
3gcoVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.447
3gdsVAL_TYR_TYR_PHESerine endoprotease DegS3.4.21.1070.447
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.447
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.447
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.447
3wbwNDPPutative 2,5-diketo-D-gluconic acid reductase/0.447
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4ia2BIVVitamin D3 receptor A/0.447
4ia7BIVVitamin D3 receptor A/0.447
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4u2lSFDCholesterol oxidase1.1.3.60.447
4v12POGMaoC like domain protein/0.447
1db1VDXVitamin D3 receptor/0.446
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.446
1yinCM3Estrogen receptor/0.446
2etrY27Rho-associated protein kinase 12.7.11.10.446
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.446
2w98P1ZProstaglandin reductase 21.3.1.480.446
2x9fX9FEphrin type-B receptor 42.7.10.10.446
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.446
2znnS44Peroxisome proliferator-activated receptor alpha/0.446
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.446
3eel53TUncharacterized protein/0.446
3fgoCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.446
3jwm5WBDihydrofolate reductase/0.446
3mdvCL6Cholesterol 24-hydroxylase/0.446
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.446
3slkNDPPolyketide synthase extender module 2/0.446
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.446
4ltsLTSNicotinamide phosphoribosyltransferase2.4.2.120.446
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
1bygSTUTyrosine-protein kinase CSK/0.445
1d3gBREDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.445
1f4fTP3Thymidylate synthase/0.445
1fmlRTLRetinol dehydratase/0.445
1hk3T44Serum albumin/0.445
1ie8KH1Vitamin D3 receptor/0.445
1ju6LYAThymidylate synthase2.1.1.450.445
1r9oFLPCytochrome P450 2C9/0.445
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
1zg32HIIsoflavone 4'-O-methyltransferase/0.445
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.445
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.445
2ittAEEEpidermal growth factor receptor2.7.10.10.445
2jg7NADAntiquitin/0.445
2ydvNECAdenosine receptor A2a/0.445
2yiuSMACytochrome b/0.445
3d7kD7KBenzaldehyde lyase/0.445
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
3nhkVAPRibosyldihydronicotinamide dehydrogenase [quinone]/0.445
3w5tLHPVitamin D3 receptor/0.445
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.445
4dscA8SAbscisic acid receptor PYL3/0.445
4elf35IDihydrofolate reductase/0.445
4em9TCEPeroxisome proliferator-activated receptor gamma/0.445
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4iah1DXAlr2278 protein/0.445
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.445
4ktl1CQCytochrome P450/0.445
4nmbFADBifunctional protein PutA/0.445
4o71CPBBromodomain-containing protein 4/0.445
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.444
1uyfPU1Heat shock protein HSP 90-alpha/0.444
1w22NHBHistone deacetylase 83.5.1.980.444
2iogIOGEstrogen receptor/0.444
2tscCB3Thymidylate synthase/0.444
2wi72KLHeat shock protein HSP 90-alpha/0.444
2y02Y01Beta-1 adrenergic receptor/0.444
2zlcVDXVitamin D3 receptor/0.444
3cndFADPolyamine oxidase FMS1/0.444
3cx5SMACytochrome b/0.444
3gyiFADCholesterol oxidase1.1.3.60.444
3mnrSD1Heat shock protein HSP 90-alpha/0.444
3mqe416Prostaglandin G/H synthase 21.14.99.10.444
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.444
3uleC69Actin-related protein 3/0.444
3uvvREARetinoic acid receptor RXR-alpha/0.444
3vtbTKAVitamin D3 receptor/0.444
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4burNADApoptosis-inducing factor 1, mitochondrial1.1.10.444
4i8vBHFCytochrome P450 1A11.14.14.10.444
4jx1CAHCamphor 5-monooxygenase1.14.15.10.444
5iu4ZMAAdenosine receptor A2a/0.444
5iubCLRAdenosine receptor A2a/0.444
1ay0TPPTransketolase 12.2.1.10.443
1fm4DXCMajor pollen allergen Bet v 1-L/0.443
1kzuRG1Light-harvesting protein B-800/850 alpha chain/0.443
1kzuRG1Light-harvesting protein B-800/850 beta chain/0.443
1ove358Mitogen-activated protein kinase 14/0.443
1qiqACCIsopenicillin N synthase1.21.3.10.443
1sj0E4DEstrogen receptor/0.443
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.443
2nnhREACytochrome P450 2C8/0.443
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.443
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.443
2yncYNCGlycylpeptide N-tetradecanoyltransferase/0.443
3bhlTHGThymidylate synthase/0.443
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.443
3ezpB3NHistone deacetylase 83.5.1.980.443
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.443
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
3opdHIEHeat shock protein 83/0.443
4bchT7ZCyclin-dependent kinase 92.7.11.220.443
4eiyZMAAdenosine receptor A2a/0.443
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4l9q9TPSerum albumin/0.443
4mxeACON-acetyltransferase ESCO12.3.10.443
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4xzmNAPAldo-keto reductase family 1 member B101.1.10.443
4z34ON7Lysophosphatidic acid receptor 1/0.443
1o6qR17Squalene--hopene cyclase4.2.1.1290.442
1pz1NAPGeneral stress protein 69/0.442
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.442
2b35TCLEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2hamC33Vitamin D3 receptor/0.442
2uxpCLMHTH-type transcriptional regulator TtgR/0.442
3mg3ECHOrange carotenoid-binding protein/0.442
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
3s7a684Dihydrofolate reductase1.5.1.30.442
3vey0H5Glucokinase2.7.1.20.442
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.442
4a95NHWGlycylpeptide N-tetradecanoyltransferase/0.442
4bewCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.442
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.442
4iwv1J9Glucokinase2.7.1.20.442
4k5y1Q5Corticotropin-releasing factor receptor 1/0.442
4z35ON9Lysophosphatidic acid receptor 1/0.442
1fkoEFZGag-Pol polyprotein2.7.7.490.441
1pkfEPDEpothilone C/D epoxidase1.140.441
1q5dEPBEpothilone C/D epoxidase1.140.441
1w06W05Isopenicillin N synthase1.21.3.10.441
2hc4VDXVitamin D3 receptor A/0.441
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.441
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2wsaMYAGlycylpeptide N-tetradecanoyltransferase/0.441
3ds6A17Mitogen-activated protein kinase 14/0.441
3lalKRVGag-Pol polyprotein2.7.7.490.441
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.441
3vruYS3Vitamin D3 receptor/0.441
3w5p4OAVitamin D3 receptor/0.441
4awo99BHeat shock protein HSP 90-alpha/0.441
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4i7fNVEGag-Pol polyprotein2.7.7.490.441
4jvnYUGEstrogen sulfotransferase2.8.2.40.441
4pd6URINucleoside permease/0.441
4ri1ACOUDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase2.3.1.2020.441
5br4NADLactaldehyde reductase1.1.1.770.441
1bq1CB3Thymidylate synthase/0.440
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1lwlDSOCamphor 5-monooxygenase1.14.15.10.440
1uykPUXHeat shock protein HSP 90-alpha/0.440
2ca0PXICytochrome P450 monooxygenase PikC/0.440
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.440
2j4z626Aurora kinase A2.7.11.10.440
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.440
2yaaATPDeath-associated protein kinase 2/0.440
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.440
3c3xNAPEugenol synthase 11.1.1.3180.440
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.440
3fsuC2F5,10-methylenetetrahydrofolate reductase1.5.1.200.440
3gobHXXDdmC/0.440
3w0jT08Vitamin D3 receptor/0.440
4a87NARMajor pollen allergen Bet v 1-A/0.440
4ku3MYA3-oxoacyl-[ACP] synthase III/0.440
4mleVO1Glucokinase2.7.1.20.440
4nc3ERM5-hydroxytryptamine receptor 2B/0.440
4nieNBHNuclear receptor ROR-gamma/0.440
4r20AERCytochrome P450 family 17 polypeptide 2/0.440
4rbs0RVMetallo-beta-lactamase type 2/0.440
4rw4494Gag-Pol polyprotein2.7.7.490.440
4ucnMYAGlycylpeptide N-tetradecanoyltransferase/0.440
4xe606UDihydrofolate reductase1.5.1.30.440
3pwhZMAAdenosine receptor A2a/0.440
3qakUKAAdenosine receptor A2a/0.440