sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2hb7 | O1C | Vitamin D3 receptor |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2hb7 | O1C | Vitamin D3 receptor | / | 1.000 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.825 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.729 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.719 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.715 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.711 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.700 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.699 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.697 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.688 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.680 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.676 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.674 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.673 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.673 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.673 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.672 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.672 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.672 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.671 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.669 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.659 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.654 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.653 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.652 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.650 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.650 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.648 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.647 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.646 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.645 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.645 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.644 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.643 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.642 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.640 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.640 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.640 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.639 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.639 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.639 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.638 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.635 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.633 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.630 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.629 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.629 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.626 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.626 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.625 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.625 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.625 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.619 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.618 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.618 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.615 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.614 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.613 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.612 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.611 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.605 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.600 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.599 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.592 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.591 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.582 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.581 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.577 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.574 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.542 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.469 | |
| 4l9k | EHF | Serum albumin | / | 0.468 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.459 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.455 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.449 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.449 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.447 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.446 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.443 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.440 |