sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2gz7 | D3F | Orf1a polyprotein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2gz7 | D3F | Orf1a polyprotein | / | 1.000 | |
| 2gz8 | F3F | Orf1a polyprotein | / | 0.535 | |
| 2op9 | WR1 | Orf1ab polyprotein | / | 0.516 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.500 | |
| 2qiq | CYV | Replicase polyprotein 1ab | / | 0.497 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.467 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.466 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.458 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.447 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.443 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.441 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.440 |