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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2gpvOHTEstrogen-related receptor gamma

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2gpvOHTEstrogen-related receptor gamma/1.000
1s9qOHTEstrogen-related receptor gamma/0.569
2jf9OHTEstrogen receptor/0.511
2p7zOHTEstrogen-related receptor gamma/0.506
1yinCM3Estrogen receptor/0.491
1xp6AIUEstrogen receptor/0.489
2ewpTXFEstrogen-related receptor gamma/0.482
2gpuOHTEstrogen-related receptor gamma/0.480
1sj0E4DEstrogen receptor/0.478
1s9pDESEstrogen-related receptor gamma/0.467
2qe4JJ3Estrogen receptor/0.465
1uomPTIEstrogen receptor/0.455
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.454
1errRALEstrogen receptor/0.452
3a1l2CCCytochrome P450/0.444