sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2gil | GTP | Ras-related protein Rab-6A |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2gil | GTP | Ras-related protein Rab-6A | / | 1.000 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.588 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.585 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.580 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.580 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.579 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.576 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.561 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.559 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.547 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.545 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.542 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.542 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.536 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.533 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.529 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.523 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.518 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.514 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.513 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.513 | |
| 3lbn | GNP | GTPase HRas | / | 0.513 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.512 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.509 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.504 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.494 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.489 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.485 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.484 | |
| 4mit | GTP | Rho-related protein racC | / | 0.482 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.481 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.481 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.478 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.477 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.477 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.477 | |
| 3oiu | GNP | GTPase HRas | / | 0.474 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.473 | |
| 4k81 | GTP | GTPase HRas | / | 0.473 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.473 | |
| 3l8y | GNP | GTPase HRas | / | 0.471 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.471 | |
| 5b2z | GNP | GTPase HRas | / | 0.471 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.465 | |
| 4dlt | GNP | GTPase HRas | / | 0.463 | |
| 1zd9 | GDP | ADP-ribosylation factor-like protein 8A | / | 0.462 | |
| 3oiv | GNP | GTPase HRas | / | 0.462 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.461 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.460 | |
| 3i3s | GNP | GTPase HRas | / | 0.459 | |
| 4uj3 | GNP | Ras-related protein Rab-11A | / | 0.458 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.457 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.455 | |
| 3v4f | GNP | GTPase HRas | / | 0.455 | |
| 4g0n | GNP | GTPase HRas | / | 0.453 | |
| 1yid | ATP | Tryptophan--tRNA ligase 2 | 6.1.1.2 | 0.452 | |
| 4hdo | GNP | Ras-related protein Rap-1b | / | 0.452 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.451 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.450 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.446 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.445 | |
| 5c46 | GSP | Ras-related protein Rab-11A | / | 0.443 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.442 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.440 | |
| 3ddc | GNP | GTPase HRas | / | 0.440 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.440 | |
| 4uj5 | GNP | Ras-related protein Rab-11A | / | 0.440 |