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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ghtSER_PRO_THR_PRO_SEPCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 13.1.3.16

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2ghtSER_PRO_THR_PRO_SEPCarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 13.1.3.161.000
1fgxU5PBeta-1,4-galactosyltransferase 1/0.515
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.506
3bm4ADVADP-sugar pyrophosphatase3.6.1.130.503
1rd4L08Integrin alpha-L/0.500
2gpvOHTEstrogen-related receptor gamma/0.496
1n71COAAac(6')-Ii protein/0.494
3rtnRTNBeta-secretase 13.4.23.460.493
3jwcEKBDihydrofolate reductase/0.492
1kijNOVDNA gyrase subunit B/0.490
3qgzADNHistidine triad nucleotide-binding protein 130.490
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.488
3zsh469Mitogen-activated protein kinase 14/0.487
3pngH4BNitric oxide synthase, brain1.14.13.390.486
3sqyQ11Dihydrofolate reductase1.5.1.30.485
1hv9UD1Bifunctional protein GlmU/0.481
2qjpANJCytochrome b/0.479
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.479
5bp7SAHSAM-dependent methyltransferase/0.479
3nloH4BNitric oxide synthase, brain1.14.13.390.478
3hv3R49Mitogen-activated protein kinase 14/0.477
3sa27DRDihydrofolate reductase/0.477
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.477
5bn4ANPV-type ATP synthase alpha chain/0.477
1rd7FOLDihydrofolate reductase1.5.1.30.476
1yqj6NPMitogen-activated protein kinase 14/0.476
3sruQ26Dihydrofolate reductase1.5.1.30.474
2mjpANPdITP/XTP pyrophosphatase3.6.1.190.473
2fmn4HF5,10-methylenetetrahydrofolate reductase1.5.1.200.472
3acy702Dehydrosqualene synthase/0.472
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.472
3cqeP91Wee1-like protein kinase2.7.10.20.471
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.471
4elb34SDihydrofolate reductase/0.471
3of1CMPcAMP-dependent protein kinase regulatory subunit/0.470
3rqmH4BNitric oxide synthase, brain1.14.13.390.470
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.470
4euxH4BNitric oxide synthase, brain1.14.13.390.470
1l8tADPAminoglycoside 3'-phosphotransferase2.7.1.950.469
1rg7MTXDihydrofolate reductase1.5.1.30.469
2dscAPRADP-sugar pyrophosphatase3.6.1.130.469
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.469
2xk6EQHSerine/threonine-protein kinase Nek22.7.11.10.469
3nlyH4BNitric oxide synthase, brain1.14.13.390.469
3pqbVGPPutative oxidoreductase/0.469
4bz7B3NHistone deacetylase/0.469
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
2bktRPFRenin3.4.23.150.468
3drcMTXDihydrofolate reductase1.5.1.30.468
3h4vDVPPteridine reductase 11.5.1.330.468
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.468
3k1wBFXRenin3.4.23.150.468
4elb34RDihydrofolate reductase/0.468
4ele31IDihydrofolate reductase/0.468
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.467
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.467
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.467
3rsv3RSBeta-secretase 13.4.23.460.467
3sh25DRDihydrofolate reductase1.5.1.30.467
3wqmB29Diterpene synthase3.1.7.80.467
4bfd8T3Beta-secretase 13.4.23.460.467
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.467
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.466
3biz61EWee1-like protein kinase2.7.10.20.466
1obnASVIsopenicillin N synthase1.21.3.10.465
1om5H4BNitric oxide synthase, brain1.14.13.390.465
3qlzQLZUncharacterized protein/0.465
1h83FADPolyamine oxidase1.5.3.140.464
1hfqMOTDihydrofolate reductase1.5.1.30.464
1jtqLY3Thymidylate synthase/0.464
2qhxFE1Pteridine reductase 11.5.1.330.464
3n0yAPCAdenylate cyclase 2/0.464
4ys0ADPProtein translocase subunit SecA/0.464
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.463
3e6tH4BNitric oxide synthase, inducible1.14.13.390.463
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.463
3tq9MTXDihydrofolate reductase/0.463
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.463
4bprFADFerredoxin--NADP reductase1.18.1.20.463
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.463
1kyzFERCaffeic acid 3-O-methyltransferase2.1.1.680.462
3fl8RARDihydrofolate reductase/0.462
3h3qH13Collagen type IV alpha-3-binding protein/0.462
4jv41ORcAMP-dependent protein kinase type I-alpha regulatory subunit/0.462
4l7j1W2Beta-secretase 13.4.23.460.462
1xuoLA1Integrin alpha-L/0.461
2qk8MTXDihydrofolate reductase/0.461
3nlzH4BNitric oxide synthase, brain1.14.13.390.461
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.461
4au7SAHHistone-lysine N-methyltransferase KMT5C2.1.1.430.461
1blzACVIsopenicillin N synthase1.21.3.10.460
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.460
4pmjNAPPutative oxidoreductase/0.460
5iqaGNPBifunctional AAC/APH2.3.10.460
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.459
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.459
2isc223Purine nucleoside phosphorylase, putative/0.459
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.459
3c36KAIGlutamate receptor ionotropic, kainate 1/0.459
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.459
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
1qgyFADFerredoxin--NADP reductase1.18.1.20.458
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.458
2z7gEH9Adenosine deaminase3.5.4.40.458
3n0z3ATAdenylate cyclase 2/0.458
1ddrMTXDihydrofolate reductase1.5.1.30.457
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.457
2z2w770Wee1-like protein kinase2.7.10.20.457
3fowIMHPurine nucleoside phosphorylase/0.457
3jwtH4BNitric oxide synthase, brain1.14.13.390.457
3ns2PYVAbscisic acid receptor PYL2/0.457
3ufl508Beta-secretase 13.4.23.460.457
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4htx19FcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.457
4rh10TTSpore photoproduct lyase/0.457
4x5fFOLDihydrofolate reductase1.5.1.30.457
1dtnAPGMandelate racemase/0.456
1rc4DDFDihydrofolate reductase1.5.1.30.456
1zprCB3Thymidylate synthase/0.456
2clfF6FTryptophan synthase alpha chain/0.456
2hm9TRRDihydrofolate reductase1.5.1.30.456
3srsM23Dihydrofolate reductase1.5.1.30.456
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
4ea13RXDehydrosqualene synthase/0.456
4iix1EGMicrocin C7 self-immunity protein MccF/0.456
4jsgH4BNitric oxide synthase, brain1.14.13.390.456
1ia9ANPTransient receptor potential cation channel subfamily M member 72.7.11.10.455
1nbhSAMGlycine N-methyltransferase2.1.1.200.455
1tllFMNNitric oxide synthase, brain1.14.13.390.455
2mokFMNFlavodoxin 1/0.455
2obyNAPQuinone oxidoreductase PIG310.455
2vbpVB1Isopenicillin N synthase1.21.3.10.455
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
3g72A6TRenin3.4.23.150.455
3nj0PYVAbscisic acid receptor PYL2/0.455
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.455
3sa16DRDihydrofolate reductase/0.455
3uq9TBNPutative adenosine kinase/0.455
3zrrPXGSerine-pyruvate aminotransferase (AgxT)/0.455
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.455
4wx2F6FTryptophan synthase alpha chain/0.455
4wx2F6FTryptophan synthase beta chain4.2.1.200.455
1cqp803Integrin alpha-L/0.454
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
1re0AFBADP-ribosylation factor 1/0.454
1re0AFBARF guanine-nucleotide exchange factor 1/0.454
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.454
3bi6396Wee1-like protein kinase2.7.10.20.454
3jziJZLBiotin carboxylase6.3.4.140.454
3w0tHPULactoylglutathione lyase4.4.1.50.454
1av5AP2Histidine triad nucleotide-binding protein 130.453
1jraFADFAD-linked sulfhydryl oxidase ERV21.8.3.20.453
2xvmSAHTellurite methyltransferase2.1.1.2650.453
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.453
3to3ATPPetrobactin biosynthesis protein AsbB/0.453
3tptADPSerine/threonine-protein kinase toxin HipA/0.453
3ufoH4BNitric oxide synthase, brain1.14.13.390.453
3uftH4BNitric oxide synthase, brain1.14.13.390.453
4af3VX6Aurora kinase B2.7.11.10.453
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.453
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.453
4xe606UDihydrofolate reductase1.5.1.30.453
1ewyFADFerredoxin--NADP reductase1.18.1.20.452
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.452
2ejzSAHDiphthine synthase/0.452
2io6330Wee1-like protein kinase2.7.10.20.452
2ydoADNAdenosine receptor A2a/0.452
3c34KAIGlutamate receptor ionotropic, kainate 1/0.452
3fl9TOPDihydrofolate reductase/0.452
3nr4PYVAbscisic acid receptor PYL2/0.452
3sl8JN7cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
4fizCUE17beta-hydroxysteroid dehydrogenase/0.452
1dg7WRBDihydrofolate reductase1.5.1.30.451
1mc5AHEAlcohol dehydrogenase class-31.1.1.10.451
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2jf6S55Strictosidine-O-beta-D-glucosidase3.2.1.1050.451
2pupADPMethylthioribose kinase2.7.1.1000.451
2q5qKPVIndole-3-pyruvate decarboxylase4.1.1.740.451
3h3sH15Collagen type IV alpha-3-binding protein/0.451
3srwQ27Dihydrofolate reductase1.5.1.30.451
4at2ASDPossible succinate dehydrogenase/0.451
4b1e6T6Beta-secretase 13.4.23.460.451
4fevPP1Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.451
4ixgIXGDihydrofolate reductase1.5.1.30.451
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.451
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.451
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.451
5d4vYGPUncharacterized protein MJ0489/0.451
1fr8GDUBeta-1,4-galactosyltransferase 1/0.450
1hi0GTPRNA-directed RNA polymerase2.7.7.480.450
1qv1CZHObelin/0.450
1rzy5ASHistidine triad nucleotide-binding protein 130.450
2c92TP66,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.450
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.450
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.450
3cr0809Wee1-like protein kinase2.7.10.20.450
3e7gH4BNitric oxide synthase, inducible1.14.13.390.450
3n5vH4BNitric oxide synthase, brain1.14.13.390.450
3nlkH4BNitric oxide synthase, brain1.14.13.390.450
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
3vetADPnebramycin 5' synthase6.1.2.20.450
4a1oAMZBifunctional purine biosynthesis protein PurH2.1.2.30.450
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.450
4g34924Eukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.450
5je3SAHMethyl transferase/0.450
2cdcNAPGlucose 1-dehydrogenase/0.449
2vcmM11Isopenicillin N synthase1.21.3.10.449
2xytTC9Soluble acetylcholine receptor/0.449
2z3uCRRCytochrome P450/0.449
3b3mH4BNitric oxide synthase, brain1.14.13.390.449
3b7dCNIGlutamate receptor 2/0.449
3pnfH4BNitric oxide synthase, brain1.14.13.390.449
3rqjH4BNitric oxide synthase, brain1.14.13.390.449
4cx5H4BNitric oxide synthase, brain1.14.13.390.449
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.449
4kf1HT5Aryldialkylphosphatase3.1.8.10.449
4zs4ATPMyosin heavy chain kinase A2.7.11.70.449
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.448
1mczRMNBenzoylformate decarboxylase4.1.1.70.448
1tl3H20Gag-Pol polyprotein2.7.7.490.448
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.448
2wjoQUDBeta-secretase 13.4.23.460.448
2xkdT3MSerine/threonine-protein kinase Nek22.7.11.10.448
2xnn430Serine/threonine-protein kinase Nek22.7.11.10.448
2zsaADPPantothenate kinase2.7.1.330.448
3datMTXDihydrofolate reductase/0.448
3tfjTHGDimethylsulfonioproprionate demethylase DmdA2.1.1.2690.448
3tm0ANPAminoglycoside 3'-phosphotransferase2.7.1.950.448
3vf2ADPnebramycin 5' synthase6.1.2.20.448
4bgbADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases/0.448
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.290.448
4jx1CAMCamphor 5-monooxygenase1.14.15.10.448
4kfj1R0Dihydrofolate reductase1.5.1.30.448
4y9xUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.448
1k8zIAGTryptophan synthase alpha chain/0.447
1kruIPTGalactoside O-acetyltransferase2.3.1.180.447
1krv147Galactoside O-acetyltransferase2.3.1.180.447
1q5dEPBEpothilone C/D epoxidase1.140.447
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.447
2q0gUPUPoly(A) polymerase, putative/0.447
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.447
2vqqTFGHistone deacetylase 43.5.1.980.447
2wo7ASVIsopenicillin N synthase1.21.3.10.447
2x7hPFNProstaglandin reductase 310.447
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.447
3ar612DSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.447
3hggCHDCmeR/0.447
3n63XFNNitric oxide synthase, brain1.14.13.390.447
3nnzH4BNitric oxide synthase, brain1.14.13.390.447
3nw2H4BNitric oxide synthase, inducible1.14.13.390.447
3qly55VUncharacterized protein/0.447
3rqlH4BNitric oxide synthase, brain1.14.13.390.447
3ufwH4BNitric oxide synthase, brain1.14.13.390.447
4a4l939Serine/threonine-protein kinase PLK12.7.11.210.447
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.447
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.447
5aglH4BNitric oxide synthase, brain1.14.13.390.447
1dnaCB3Thymidylate synthase/0.446
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.446
1u0wSTLChalcone synthase 22.3.1.740.446
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.446
3h0bB35Beta-secretase 13.4.23.460.446
3i5xANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.446
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.446
3kmyD8YBeta-secretase 13.4.23.460.446
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.446
4c49HCYCorticosteroid-binding globulin/0.446
4h3g10QBeta-secretase 13.4.23.460.446
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
4j6i1JVPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1e64FADFerredoxin--NADP reductase1.18.1.20.445
1ia1TQ3Dihydrofolate reductase1.5.1.30.445
2bfaCB3Pteridine reductase 11.5.1.330.445
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.445
2r86ATP5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase/0.445
2vn1FK5Peptidylprolyl isomerase/0.445
3ebf332Nitric oxide synthase, inducible1.14.13.390.445
3ex8AIFRiboflavin biosynthesis protein RibD1.1.1.1930.445
3g70A5TRenin3.4.23.150.445
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.445
3kpfFADPolyamine oxidase1.5.3.140.445
3l6jZ90Alr2278 protein/0.445
3n60XFNNitric oxide synthase, brain1.14.13.390.445
3n66XFNNitric oxide synthase, brain1.14.13.390.445
3rqkH4BNitric oxide synthase, brain1.14.13.390.445
3rviRVIBeta-secretase 13.4.23.460.445
3ufrH4BNitric oxide synthase, brain1.14.13.390.445
3vjcZGASqualene synthase2.5.1.210.445
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.445
4fgh0U6Dihydrofolate reductase1.5.1.30.445
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.445
4j6bPLOCytochrome P450 monooxygenase/0.445
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4ugaQ05Nitric oxide synthase oxygenase1.14.13.1650.445
5dstSAHProtein arginine N-methyltransferase 82.1.10.445
1b87ACOAac(6')-Ii protein/0.444
1k2uH4BNitric oxide synthase, brain1.14.13.390.444
1synF89Thymidylate synthase/0.444
2b8jADNClass B acid phosphatase3.1.3.20.444
2g274LGRenin3.4.23.150.444
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2w3mFOLDihydrofolate reductase1.5.1.30.444
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.444
3ezpB3NHistone deacetylase 83.5.1.980.444
3fqjGDPDecapping and exoribonuclease protein3.1.130.444
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3nxyD2HDihydrofolate reductase1.5.1.30.444
3sgy06WDihydrofolate reductase1.5.1.30.444
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4kd79DRDihydrofolate reductase1.5.1.30.444
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
4qfzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.444
4x5jFOLDihydrofolate reductase1.5.1.30.444
1ddsMTXDihydrofolate reductase1.5.1.30.443
1e2lTMCThymidine kinase/0.443
1kuxCA3Serotonin N-acetyltransferase/0.443
1vafH4BNitric oxide synthase, inducible1.14.13.390.443
2bu9HFVIsopenicillin N synthase1.21.3.10.443
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.443
2rabNADGlutathione amide reductase/0.443
2w3vTOPDihydrofolate reductase/0.443
2w6oOA3Biotin carboxylase6.3.4.140.443
2zx8ZX8Alpha-L-fucosidase, putative/0.443
3c35KAIGlutamate receptor ionotropic, kainate 1/0.443
3jwuH4BNitric oxide synthase, brain1.14.13.390.443
3nxvD2FDihydrofolate reductase1.5.1.30.443
3occDIHPurine nucleoside phosphorylase DeoD-type/0.443
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.443
4gr9372Ribosyldihydronicotinamide dehydrogenase [quinone]/0.443
4h3j10WBeta-secretase 13.4.23.460.443
4k88HFGBifunctional glutamate/proline--tRNA ligase6.1.1.150.443
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.443
4y6gF6FTryptophan synthase alpha chain/0.443
5iqbGNPBifunctional AAC/APH2.3.10.443
5iqdGNPBifunctional AAC/APH2.3.10.443
1bzfTMQDihydrofolate reductase1.5.1.30.442
1up6NAD6-phospho-beta-glucosidase BglT3.2.1.860.442
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.442
2g86UMPThymidylate synthase/0.442
2xkc4VQSerine/threonine-protein kinase Nek22.7.11.10.442
2zx5ZX5Alpha-L-fucosidase, putative/0.442
3aezGDPPantothenate kinase2.7.1.330.442
3cv9VDXVitamin D3 dihydroxylase/0.442
3oxk5GPHistidine triad nucleotide-binding protein30.442
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.442
3tqbFOLDihydrofolate reductase/0.442
4cqnILALeucine--tRNA ligase/0.442
4ej1FOLDihydrofolate reductase1.5.1.30.442
4jsfH4BNitric oxide synthase, brain1.14.13.390.442
4luxQJ8Nitric oxide synthase, brain1.14.13.390.442
5bp9SAHPutative methyltransferase protein/0.442
1hb3SCVIsopenicillin N synthase1.21.3.10.441
1j7lADPAminoglycoside 3'-phosphotransferase2.7.1.950.441
1rx4DDFDihydrofolate reductase1.5.1.30.441
1wklATPNucleoside diphosphate kinase/0.441
2c3u2TPPyruvate synthase/0.441
2d06ESTSulfotransferase 1A12.8.2.10.441
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.441
2q0fU5PPoly(A) polymerase, putative/0.441
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.441
3d5wADPSerine/threonine-protein kinase PLK/0.441
3inrGDUUDP-galactopyranose mutase5.4.99.90.441
3llaACPMyosin heavy chain kinase A2.7.11.70.441
3pneH4BNitric oxide synthase, brain1.14.13.390.441
3sr5Q12Dihydrofolate reductase1.5.1.30.441
3zeiAWHO-acetylserine sulfhydrylase/0.441
3zkyWT4Isopenicillin N synthase1.21.3.10.441
4elf35IDihydrofolate reductase/0.441
4lv8ADPRhoptry protein 5 C/0.441
4mv1ADPBiotin carboxylase6.3.4.140.441
7dfrFOLDihydrofolate reductase1.5.1.30.441
1djqFMNTrimethylamine dehydrogenase1.5.8.20.440
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.440
1xp9AIJEstrogen receptor/0.440
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.440
1zzlTZYMitogen-activated protein kinase 14/0.440
2i8cADPD-alanine--D-alanine ligase/0.440
2xkfBX1Serine/threonine-protein kinase Nek22.7.11.10.440
3eek53SUncharacterized protein/0.440
3fpbATPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.440
3ge7AFQQueuine tRNA-ribosyltransferase2.4.2.290.440
3i8aN22Dihydrofolate reductase1.5.1.30.440
3x025GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.440
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.440
4b7754MBeta-secretase 13.4.23.460.440
4da7AC2Purine nucleoside phosphorylase DeoD-type2.4.2.10.440
4h6pFMNChromate reductase/0.440