sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2gfk | VII | Metallo-beta-lactamase L1 type 3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2gfk | VII | Metallo-beta-lactamase L1 type 3 | / | 1.000 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.542 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.540 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.527 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.525 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.521 | |
| 3n0y | APC | Adenylate cyclase 2 | / | 0.521 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.513 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.513 | |
| 3acy | 702 | Dehydrosqualene synthase | / | 0.507 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.507 | |
| 3anl | SYC | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.506 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.505 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.505 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.505 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.503 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.503 | |
| 3kb0 | A8S | Abscisic acid receptor PYL2 | / | 0.502 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.501 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.501 | |
| 1nbh | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.498 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.496 | |
| 2pjl | 047 | Steroid hormone receptor ERR1 | / | 0.496 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.494 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.493 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.493 | |
| 4kyh | ZST | Lactoylglutathione lyase | 4.4.1.5 | 0.490 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.489 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.488 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.488 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.488 | |
| 1dpm | EBP | Parathion hydrolase | 3.1.8.1 | 0.485 | |
| 4ec3 | REN | Reticuline oxidase | 1.21.3.3 | 0.485 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 4f79 | P53 | Putative phospho-beta-glucosidase | / | 0.483 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.482 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.482 | |
| 1vbm | YSA | Tyrosine--tRNA ligase | 6.1.1.1 | 0.481 | |
| 3tfn | 2CJ | Dehydrosqualene synthase | / | 0.481 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.481 | |
| 4khn | XG4 | DNA-directed DNA polymerase | / | 0.481 | |
| 3hf8 | ML0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.479 | |
| 2j62 | GSZ | O-GlcNAcase NagJ | / | 0.478 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.478 | |
| 3upt | TPP | Transketolase | / | 0.478 | |
| 1yun | ATP | Probable nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.477 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.477 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.476 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.475 | |
| 2r7n | ADP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase | / | 0.475 | |
| 3tfp | 03L | Dehydrosqualene synthase | / | 0.475 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.475 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.475 | |
| 1kru | IPT | Galactoside O-acetyltransferase | 2.3.1.18 | 0.474 | |
| 2fmn | 4HF | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.474 | |
| 2jf6 | S55 | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.474 | |
| 2v95 | HCY | Corticosteroid-binding globulin | / | 0.474 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 3d2d | REN | Reticuline oxidase | 1.21.3.3 | 0.474 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.474 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.474 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.474 | |
| 5dst | SAH | Protein arginine N-methyltransferase 8 | 2.1.1 | 0.474 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.474 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.473 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.473 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.473 | |
| 3hfb | ML4 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.473 | |
| 3n10 | CMP | Adenylate cyclase 2 | / | 0.473 | |
| 4mmf | 29Q | Na(+):neurotransmitter symporter (Snf family) | / | 0.473 | |
| 4nye | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 6.3.2.6 | 0.473 | |
| 5dsg | 0HK | Muscarinic acetylcholine receptor M4 | / | 0.473 | |
| 1c1b | GCA | Gag-Pol polyprotein | 2.7.7.49 | 0.472 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.472 | |
| 3i58 | 7NA | 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | / | 0.472 | |
| 3nlj | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.472 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.472 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.472 | |
| 4qjq | OTR | Lactoperoxidase | / | 0.472 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.472 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.471 | |
| 3rme | RME | Acidic mammalian chitinase | 3.2.1.14 | 0.471 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.471 | |
| 4k7a | DHT | Androgen receptor | / | 0.471 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.471 | |
| 3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.470 | |
| 5f2k | SAH | Uncharacterized protein | / | 0.470 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.469 | |
| 4r5w | XAV | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.469 | |
| 1qin | GIP | Lactoylglutathione lyase | 4.4.1.5 | 0.468 | |
| 3k3k | A8S | Abscisic acid receptor PYR1 | / | 0.468 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.468 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.468 | |
| 1ee1 | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.467 | |
| 1o6i | 0HZ | Chitinase B | 3.2.1.14 | 0.467 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.467 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.467 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.467 | |
| 2xpk | Z0M | O-GlcNAcase NagJ | / | 0.467 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 3roe | THM | NAD(P)H-hydrate epimerase | 5.1.99.6 | 0.467 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.467 | |
| 4cry | ACO | PanD regulatory factor | / | 0.467 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 4el9 | AFE | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.467 | |
| 4pv5 | CBW | Lactoylglutathione lyase | 4.4.1.5 | 0.467 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.466 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1nd5 | 2BF | Prostatic acid phosphatase | 3.1.3.2 | 0.466 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.466 | |
| 2ywv | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | / | 0.466 | |
| 3kro | IPE | Geranyl diphosphate synthase large subunit | / | 0.466 | |
| 3q99 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.466 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.466 | |
| 1afs | TES | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.465 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.465 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.465 | |
| 3n0z | 3AT | Adenylate cyclase 2 | / | 0.465 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.465 | |
| 1kdm | DHT | Sex hormone-binding globulin | / | 0.464 | |
| 1lke | DOG | Bilin-binding protein | / | 0.464 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.464 | |
| 1u3g | THF | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.464 | |
| 1xmm | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.464 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.464 | |
| 3b3p | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.464 | |
| 3qtt | ANP | Pantothenate synthetase | / | 0.464 | |
| 4fj0 | HHF | 17beta-hydroxysteroid dehydrogenase | / | 0.464 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1t76 | DHT | Androgen receptor | / | 0.463 | |
| 2be2 | R22 | Gag-Pol polyprotein | 2.7.7.49 | 0.463 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.463 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.463 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.463 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.463 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.463 | |
| 1rvv | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 2mm3 | GCH | Gastrotropin | / | 0.462 | |
| 3anm | SYD | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.462 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.462 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.462 | |
| 4cby | KEE | Histone deacetylase 4 | 3.5.1.98 | 0.462 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.461 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.461 | |
| 1srh | MOB | Streptavidin | / | 0.461 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.461 | |
| 3aq0 | ISY | Solanesyl diphosphate synthase 3, chloroplastic/mitochondrial | 2.5.1.85 | 0.461 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.461 | |
| 3zcn | ATP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.461 | |
| 3zvu | A8S | Abscisic acid receptor PYR1 | / | 0.461 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 1m9k | 7NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.460 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3k90 | A8S | Abscisic acid receptor PYR1 | / | 0.460 | |
| 3znr | NU9 | Histone deacetylase 7 | 3.5.1.98 | 0.460 | |
| 4af3 | VX6 | Aurora kinase B | 2.7.11.1 | 0.460 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.460 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.460 | |
| 1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.459 | |
| 1mab | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.459 | |
| 1w1w | AGS | Structural maintenance of chromosomes protein 1 | / | 0.459 | |
| 2b0q | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.459 | |
| 2clf | F6F | Tryptophan synthase alpha chain | / | 0.459 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.459 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.459 | |
| 3e9s | TTT | Replicase polyprotein 1ab | 3.4.22 | 0.459 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.459 | |
| 3pit | GNP | Ras-related protein M-Ras | / | 0.459 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.459 | |
| 3w0u | HPW | Lactoylglutathione lyase | 4.4.1.5 | 0.459 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 4kyk | IMN | Lactoylglutathione lyase | 4.4.1.5 | 0.459 | |
| 4zo3 | C6L | Acylhomoserine lactonase | / | 0.459 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.459 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 3c1o | NAP | Eugenol synthase | / | 0.458 | |
| 3ert | OHT | Estrogen receptor | / | 0.458 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.458 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.458 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.458 | |
| 1bye | ATA | Glutathione S-transferase 1 | 2.5.1.18 | 0.457 | |
| 1i7l | ATP | Synapsin-2 | / | 0.457 | |
| 1kij | NOV | DNA gyrase subunit B | / | 0.457 | |
| 1ltz | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.457 | |
| 2acw | UPG | Glycosyltransferase | / | 0.457 | |
| 2vku | DBE | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.457 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.457 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.457 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.457 | |
| 1e7w | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.456 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.456 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.456 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.456 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.456 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.456 | |
| 3ujl | A8S | Abscisic acid receptor PYL2 | / | 0.456 | |
| 4bmp | FMN | Protein NrdI | / | 0.456 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.456 | |
| 4h6p | FMN | Chromate reductase | / | 0.456 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.456 | |
| 5d8u | 0N8 | Polymerase acidic protein | / | 0.456 | |
| 4ami | G90 | Beta-1 adrenergic receptor | / | 0.456 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.455 | |
| 1xj7 | DHT | Androgen receptor | / | 0.455 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.455 | |
| 2qds | MCO | Metallo-beta-lactamase type 2 | / | 0.455 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.455 | |
| 3b5i | SAH | Indole-3-acetate O-methyltransferase 1 | / | 0.455 | |
| 3ele | PLP | Aminotransferase | / | 0.455 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.455 | |
| 3w8z | HTK | Putative FAD-dependent oxygenase EncM | / | 0.455 | |
| 4at2 | ASD | Possible succinate dehydrogenase | / | 0.455 | |
| 4isf | 1FX | Glucokinase | 2.7.1.2 | 0.455 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.455 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.454 | |
| 1w1r | ZEA | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.454 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.454 | |
| 1zua | TOL | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.454 | |
| 3ahe | THD | Probable phosphoketolase | / | 0.454 | |
| 3m34 | TPP | Transketolase | / | 0.454 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.454 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.454 | |
| 4fa3 | 0SL | Aldo-keto reductase family 1 member C3 | / | 0.454 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4l65 | C2F | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | 2.1.1.14 | 0.454 | |
| 4p5f | AR6 | Inosine-uridine nucleoside N-ribohydrolase | / | 0.454 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.454 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.454 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.453 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.453 | |
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.453 | |
| 3sqy | Q11 | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.453 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 4dls | GNP | GTPase HRas | / | 0.453 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.453 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.453 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.453 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.452 | |
| 1rs6 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.452 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.452 | |
| 1xuz | MMN | Capsule biosynthesis protein | / | 0.452 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.452 | |
| 2hai | PFI | Polyprotein | / | 0.452 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.452 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.452 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.452 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3ubd | SL0 | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.452 | |
| 4fj1 | GEN | 17beta-hydroxysteroid dehydrogenase | / | 0.452 | |
| 4gn6 | TYL | Lactoperoxidase | 1.11.1.7 | 0.452 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.452 | |
| 4jqa | ID8 | Aldo-keto reductase family 1 member C2 | / | 0.452 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.452 | |
| 1dre | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.451 | |
| 1pxg | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.451 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.451 | |
| 1yy4 | 4NA | Estrogen receptor beta | / | 0.451 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.451 | |
| 2bn4 | FAD | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.451 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.451 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.451 | |
| 3tdk | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.451 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 4k88 | HFG | Bifunctional glutamate/proline--tRNA ligase | 6.1.1.15 | 0.451 | |
| 4xwt | U5P | Ribonuclease J | / | 0.451 | |
| 5bu2 | ADP | Uncharacterized protein | / | 0.451 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.451 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.450 | |
| 1rt1 | MKC | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1tvu | CB3 | Thymidylate synthase | / | 0.450 | |
| 2ay3 | MPP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.450 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.450 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 2pdf | ZST | Aldose reductase | 1.1.1.21 | 0.450 | |
| 2pix | DHT | Androgen receptor | / | 0.450 | |
| 2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.450 | |
| 3bmq | AX5 | Pteridine reductase | / | 0.450 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.450 | |
| 3dla | NXX | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.450 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.450 | |
| 3hgg | CHD | CmeR | / | 0.450 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.450 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.450 | |
| 4fsa | 0V3 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.450 | |
| 4hai | I23 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.450 | |
| 4lwx | MU2 | Ribosome inactivating protein | / | 0.450 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.450 | |
| 4yao | 2AM | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.450 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.450 | |
| 1a50 | FIP | Tryptophan synthase alpha chain | / | 0.449 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.449 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.449 | |
| 1sl9 | CZH | Obelin | / | 0.449 | |
| 2ght | SER_PRO_THR_PRO_SEP | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 | 3.1.3.16 | 0.449 | |
| 2piw | DHT | Androgen receptor | / | 0.449 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.449 | |
| 3iw8 | HIZ | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3n39 | FMN | Protein NrdI | / | 0.449 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.449 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 3ufv | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.449 | |
| 4b1f | KRH | Glutamate racemase | / | 0.449 | |
| 4dlw | GNP | GTPase HRas | / | 0.449 | |
| 4imu | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.449 | |
| 4x81 | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.449 | |
| 1f3e | DPZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.448 | |
| 1gsf | EAA | Glutathione S-transferase A1 | 2.5.1.18 | 0.448 | |
| 1l2i | ETC | Estrogen receptor | / | 0.448 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.448 | |
| 1vhn | FMN | tRNA-dihydrouridine synthase | / | 0.448 | |
| 2j5s | KTA | Alr4455 protein | / | 0.448 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.448 | |
| 3a7d | FBN | Catechol O-methyltransferase | 2.1.1.6 | 0.448 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.448 | |
| 3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.448 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3vw9 | HPJ | Lactoylglutathione lyase | 4.4.1.5 | 0.448 | |
| 4a1o | AMZ | Bifunctional purine biosynthesis protein PurH | 2.1.2.3 | 0.448 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.448 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.448 | |
| 4jhi | EMU | Nodulin-13 | / | 0.448 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.448 | |
| 4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.448 | |
| 1b7t | ADP | Myosin heavy chain, striated muscle | / | 0.447 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.447 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 2am9 | TES | Androgen receptor | / | 0.447 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.447 | |
| 3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3pne | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 3rc7 | TLO | Sugar 3-ketoreductase | / | 0.447 | |
| 3t31 | DCQ | Sulfide-quinone reductase | / | 0.447 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.447 | |
| 3vi7 | CBD | Hematopoietic prostaglandin D synthase | / | 0.447 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.447 | |
| 4a39 | GEM | Uncharacterized protein | / | 0.447 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.447 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.447 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4oic | A8S | Bet v I allergen-like | / | 0.447 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.447 | |
| 1kia | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.446 | |
| 1kyz | FER | Caffeic acid 3-O-methyltransferase | 2.1.1.68 | 0.446 | |
| 1q6p | 213 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.446 | |
| 1qw5 | 14W | Nitric oxide synthase, inducible | 1.14.13.39 | 0.446 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 2fjm | 073 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.446 | |
| 2qpy | DHT | Androgen receptor | / | 0.446 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.446 | |
| 2za0 | MGI | Lactoylglutathione lyase | 4.4.1.5 | 0.446 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.446 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3seq | NXX | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.446 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4a51 | DQ8 | Kinesin-like protein KIF11 | / | 0.446 | |
| 4ifv | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 4ktt | SAM | S-adenosylmethionine synthase isoform type-2 | 2.5.1.6 | 0.446 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.446 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.446 | |
| 2ycz | I32 | Beta-1 adrenergic receptor | / | 0.446 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.446 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.445 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1mlz | PLP | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.445 | |
| 1p16 | GTP | mRNA-capping enzyme subunit alpha | 2.7.7.50 | 0.445 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.445 | |
| 2b8j | ADN | Class B acid phosphatase | 3.1.3.2 | 0.445 | |
| 2clm | F6F | Tryptophan synthase alpha chain | / | 0.445 | |
| 2dy9 | ADP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.445 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.445 | |
| 2w0h | NDP | Trypanothione reductase | / | 0.445 | |
| 2ylp | TES | Androgen receptor | / | 0.445 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.445 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 3ght | LDT | Aldose reductase | 1.1.1.21 | 0.445 | |
| 3jt4 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 3qw2 | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.445 | |
| 3u8d | U8D | Phospholipase A2, membrane associated | / | 0.445 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.445 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4i5x | FLF | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.445 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.445 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.445 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.445 | |
| 4o7n | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 6.3.2.6 | 0.445 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.445 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.444 | |
| 1q63 | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.444 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.444 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.444 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1zyd | ATP | eIF-2-alpha kinase GCN2 | / | 0.444 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.444 | |
| 2bns | MST | Reaction center protein L chain | / | 0.444 | |
| 2nod | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.444 | |
| 2opb | F21 | Phenylethanolamine N-methyltransferase | 2.1.1.28 | 0.444 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.444 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3hav | ATP | Aminoglycoside phosphotransferase | / | 0.444 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 3jq7 | DX2 | Pteridine reductase, putative | / | 0.444 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3nju | ANN | Acidic phospholipase A2 3 | 3.1.1.4 | 0.444 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.444 | |
| 3tq8 | TOP | Dihydrofolate reductase | / | 0.444 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.444 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.444 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4jq3 | ZOM | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 4rbs | 0RV | Metallo-beta-lactamase type 2 | / | 0.444 | |
| 4wcx | SAM | Biotin and thiamin synthesis associated | / | 0.444 | |
| 1c1c | 612 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.443 | |
| 1fro | GSB | Lactoylglutathione lyase | 4.4.1.5 | 0.443 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 1qlt | FAD | Vanillyl-alcohol oxidase | 1.1.3.38 | 0.443 | |
| 2ofv | 242 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.443 | |
| 2pit | DHT | Androgen receptor | / | 0.443 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.443 | |
| 3dv0 | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.443 | |
| 3dv0 | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.443 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.443 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.443 | |
| 3htj | ET | EbrA repressor | / | 0.443 | |
| 3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.443 | |
| 3mec | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3nlv | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.443 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.443 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.443 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.443 | |
| 4dne | DTB | Streptavidin | / | 0.443 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.443 | |
| 4gh3 | 0EV | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.443 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.443 | |
| 4jkv | 1KS | Smoothened homolog | / | 0.443 | |
| 4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.443 | |
| 5agk | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.443 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.443 | |
| 1amo | NAP | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.442 | |
| 1m67 | BOA | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.442 | |
| 1syn | F89 | Thymidylate synthase | / | 0.442 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.442 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.442 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
| 2nr4 | FMN | Conserved protein | / | 0.442 | |
| 2plm | SIB | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | 3.5.4.28 | 0.442 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.442 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.442 | |
| 2zcq | B65 | Dehydrosqualene synthase | / | 0.442 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.442 | |
| 3axs | SFG | tRNA (guanine(26)-N(2)/guanine(27)-N(2))-dimethyltransferase | / | 0.442 | |
| 3b3n | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.442 | |
| 3hy4 | N5G | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.442 | |
| 3lm4 | HPX | Catechol 2,3-dioxygenase | / | 0.442 | |
| 3pch | CHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.442 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.442 | |
| 3zgz | 84T | Leucine--tRNA ligase | / | 0.442 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.442 | |
| 4au7 | SAH | Histone-lysine N-methyltransferase KMT5C | 2.1.1.43 | 0.442 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.442 | |
| 4lrr | CF9 | Thymidylate synthase | / | 0.442 | |
| 4xt8 | TMQ | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.442 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.442 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1gs4 | ZK5 | Androgen receptor | / | 0.441 | |
| 1nw4 | IMH | Purine nucleoside phosphorylase | / | 0.441 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.441 | |
| 1rp4 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.441 | |
| 1wop | FFO | Aminomethyltransferase | / | 0.441 | |
| 2a8s | GTP | U8 snoRNA-decapping enzyme | / | 0.441 | |
| 2b96 | ANN | Phospholipase A2 | 3.1.1.4 | 0.441 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.441 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.441 | |
| 2ikj | 393 | Aldose reductase | 1.1.1.21 | 0.441 | |
| 2isj | FMN | 5,6-dimethylbenzimidazole synthase | 1.13.11.79 | 0.441 | |
| 2kt4 | EB4 | Extracellular fatty acid-binding protein | / | 0.441 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 2xeg | CI9 | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.441 | |
| 2y67 | N21 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.441 | |
| 3c6o | 2S2 | Protein TRANSPORT INHIBITOR RESPONSE 1 | / | 0.441 | |
| 3gwn | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.441 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.441 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3kt3 | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.441 | |
| 3pdt | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 0.441 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.441 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 3ugr | IMN | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4a33 | PS8 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.441 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4cx3 | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.441 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.441 | |
| 5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.440 | |
| 1jlc | FTC | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1klm | SPP | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.440 | |
| 1vi0 | DCC | Fatty acid metabolism regulator protein | / | 0.440 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.440 | |
| 2gqn | BLP | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.440 | |
| 2q6h | CXX | Na(+):neurotransmitter symporter (Snf family) | / | 0.440 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.440 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.440 | |
| 2xnm | WGZ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.440 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.440 | |
| 3c34 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3dqr | JI2 | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 3ezp | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.440 | |
| 3fgo | ACP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 3fzf | ATP | Heat shock cognate 71 kDa protein | / | 0.440 | |
| 3ozs | OZS | Catechol O-methyltransferase | 2.1.1.6 | 0.440 | |
| 3qwi | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.440 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.440 | |
| 4avg | SL6 | Polymerase acidic protein | / | 0.440 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
| 4mm9 | FVX | Na(+):neurotransmitter symporter (Snf family) | / | 0.440 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 5bsr | COA | 4-coumarate--CoA ligase 2 | 6.2.1.12 | 0.440 | |
| 5pah | LDP | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.440 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.440 |