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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2g2hP16Tyrosine-protein kinase ABL12.7.10.2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2g2hP16Tyrosine-protein kinase ABL12.7.10.21.000
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.566
1m52P17Tyrosine-protein kinase ABL12.7.10.20.562
4af3VX6Aurora kinase B2.7.11.10.545
1bygSTUTyrosine-protein kinase CSK/0.544
3oct1N1Tyrosine-protein kinase BTK2.7.10.20.538
4twpAXITyrosine-protein kinase ABL12.7.10.20.534
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.530
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.530
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.519
4wa9AXITyrosine-protein kinase ABL12.7.10.20.517
5bvw1N1Epithelial discoidin domain-containing receptor 12.7.10.10.516
2xynVX6Abelson tyrosine-protein kinase 22.7.10.20.508
4gk2L66Ephrin type-A receptor 32.7.10.10.505
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.502
2vwx7X4Ephrin type-B receptor 42.7.10.10.500
2of4979Tyrosine-protein kinase Lck2.7.10.20.499
2of2547Tyrosine-protein kinase Lck2.7.10.20.498
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.495
3ac2KSETyrosine-protein kinase Lck2.7.10.20.495
2rl52RLVascular endothelial growth factor receptor 22.7.10.10.494
2g2fAGSTyrosine-protein kinase ABL12.7.10.20.493
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.492
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.491
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.491
2hk51BMTyrosine-protein kinase HCK2.7.10.20.490
1jpaANPEphrin type-B receptor 22.7.10.10.489
3oom507Activin receptor type-12.7.11.300.488
4bb3KKAIsopenicillin N synthase1.21.3.10.487
3ds6A17Mitogen-activated protein kinase 14/0.486
2vx07X7Ephrin type-B receptor 42.7.10.10.485
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.485
2p15EZTEstrogen receptor/0.484
4id71G0Activated CDC42 kinase 1/0.484
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.484
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.483
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.483
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.482
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.481
2xvdAS6Ephrin type-B receptor 42.7.10.10.481
3gc9B45Mitogen-activated protein kinase 112.7.11.240.481
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.481
4gk4L90Ephrin type-A receptor 32.7.10.10.481
2y6o1N1Ephrin type-A receptor 42.7.10.10.480
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.479
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.479
3h1jSMACytochrome b/0.479
4c58824Cyclin-G-associated kinase2.7.11.10.478
4ia2BIVVitamin D3 receptor A/0.477
4jia1K3Tyrosine-protein kinase JAK2/0.477
4gmy0X5Tyrosine-protein kinase JAK2/0.476
4jbtASDCytochrome P450 monooxygenase/0.476
4jbqVX6Aurora kinase A2.7.11.10.475
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.474
2y30SM8Putative repressor SimReg2/0.473
3itzP66Mitogen-activated protein kinase 14/0.473
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.473
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.473
4bgg844Activin receptor type-12.7.11.300.473
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.472
2zybKSLTyrosine-protein kinase Lck2.7.10.20.472
3ac1KZITyrosine-protein kinase Lck2.7.10.20.472
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.472
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.472
5k2bZMAAdenosine receptor A2a/0.472
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.471
3b8q900Vascular endothelial growth factor receptor 22.7.10.10.471
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.471
4jlj1NMDeoxycytidine kinase2.7.1.740.471
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.471
2vwy7X5Ephrin type-B receptor 42.7.10.10.470
2x9fX9FEphrin type-B receptor 42.7.10.10.470
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.470
2vx17X8Ephrin type-B receptor 42.7.10.10.469
3zsh469Mitogen-activated protein kinase 14/0.469
4elf35IDihydrofolate reductase/0.469
4gk3L87Ephrin type-A receptor 32.7.10.10.469
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.468
2hziJINTyrosine-protein kinase ABL12.7.10.20.468
2vwu7X1Ephrin type-B receptor 42.7.10.10.468
2xyuQ9GEphrin type-A receptor 42.7.10.10.468
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.468
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.468
2py3ACPFibroblast growth factor receptor 2/0.467
2vwz7X6Ephrin type-B receptor 42.7.10.10.467
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.467
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.467
5e8wSTUTGF-beta receptor type-12.7.11.300.467
1hb3SCVIsopenicillin N synthase1.21.3.10.466
2oh4GIGVascular endothelial growth factor receptor 22.7.10.10.466
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.466
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.466
4g2fC07Ephrin type-A receptor 32.7.10.10.466
4jlk1NODeoxycytidine kinase2.7.1.740.466
4rupH97Vitamin D3 receptor A/0.466
2j0k4STFocal adhesion kinase 12.7.10.20.465
2ofv242Tyrosine-protein kinase Lck2.7.10.20.465
2vcmM11Isopenicillin N synthase1.21.3.10.465
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.465
4bb432WEphrin type-B receptor 42.7.10.10.465
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.465
4o701QKBromodomain-containing protein 4/0.465
2b1pAIZMitogen-activated protein kinase 102.7.11.240.464
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.464
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.464
3e92G6AMitogen-activated protein kinase 14/0.464
3mtfA3FActivin receptor type-12.7.11.300.464
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.464
5e8xSTUTGF-beta receptor type-12.7.11.300.464
1blzACVIsopenicillin N synthase1.21.3.10.463
1oc1ASVIsopenicillin N synthase1.21.3.10.463
2jedLG8Protein kinase C theta type2.7.11.130.463
2vww7X2Ephrin type-B receptor 42.7.10.10.463
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.463
3adaNADSubunit alpha of sarocosine oxidase/0.463
3l0lHC3Nuclear receptor ROR-gamma/0.463
3qri919Tyrosine-protein kinase ABL12.7.10.20.463
3zewSTUEphrin type-B receptor 42.7.10.10.463
4j97ACPFibroblast growth factor receptor 2/0.463
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.463
1iyzNDPProbable quinone oxidoreductase/0.462
1qiqACCIsopenicillin N synthase1.21.3.10.462
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.462
3gxlQIGTGF-beta receptor type-12.7.11.300.462
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.462
4grb0XGCasein kinase II subunit alpha2.7.11.10.462
4iui1GQEstrogen receptor/0.462
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.462
3pwhZMAAdenosine receptor A2a/0.462
2itqITQEpidermal growth factor receptor2.7.10.10.461
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.461
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.461
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.461
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.461
4ele31IDihydrofolate reductase/0.461
4nka2K7Fibroblast growth factor receptor 1/0.461
4riyADPEpidermal growth factor receptor2.7.10.10.461
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.461
1hb1OCVIsopenicillin N synthase1.21.3.10.460
1nq7ARLNuclear receptor ROR-beta/0.460
2qoqANPEphrin type-A receptor 32.7.10.10.460
3acjKSSTyrosine-protein kinase Lck2.7.10.20.460
3q5iANPProtein kinase, putative/0.460
4j6bPLOCytochrome P450 monooxygenase/0.460
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.460
2itvANPEpidermal growth factor receptor2.7.10.10.459
2y6fM9FIsopenicillin N synthase1.21.3.10.459
2znnS44Peroxisome proliferator-activated receptor alpha/0.459
3c5uP41Mitogen-activated protein kinase 14/0.459
3gc8B45Mitogen-activated protein kinase 112.7.11.240.459
3l8sBFFMitogen-activated protein kinase 14/0.459
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.459
4iteTEYVitamin D3 receptor/0.459
4j6cSTRCytochrome P450 monooxygenase/0.459
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.459
4tuvCPZCytochrome P450 1191.140.459
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.458
1w06W05Isopenicillin N synthase1.21.3.10.458
2g78REACellular retinoic acid-binding protein 2/0.458
2vbpVB1Isopenicillin N synthase1.21.3.10.458
3a1l2CCCytochrome P450/0.458
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.458
3zk5Z18Cytochrome P450 monooxygenase PikC/0.458
1ly3COGDihydrofolate reductase1.5.1.30.457
1pp9SMACytochrome b/0.457
1ppjANYCytochrome b/0.457
2e98B29Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.457
2izrBRKCasein kinase I isoform gamma-32.7.11.10.457
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.457
3dtcVINMitogen-activated protein kinase kinase kinase 92.7.11.250.457
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.457
3p3zP3ZPutative cytochrome P450/0.457
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.457
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.456
2ban357Gag-Pol polyprotein2.7.7.490.456
2c475IDCasein kinase I isoform gamma-2/0.456
2itnANPEpidermal growth factor receptor2.7.10.10.456
2qocANPEphrin type-A receptor 32.7.10.10.456
4hvs647Mast/stem cell growth factor receptor Kit2.7.10.10.456
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.456
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.456
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.456
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.455
1qxlFR8Adenosine deaminase3.5.4.40.455
2etm7PYFocal adhesion kinase 12.7.10.20.455
2pzpACPFibroblast growth factor receptor 2/0.455
3fkoFKOMitogen-activated protein kinase 14/0.455
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.455
4i3zADPCyclin-dependent kinase 22.7.11.220.455
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.455
4l8u9AZSerum albumin/0.455
4ubsDIFPentalenic acid synthase1.14.15.110.455
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.455
5itzLOCTubulin beta-2B chain/0.455
1s19MC9Vitamin D3 receptor/0.454
2j4z626Aurora kinase A2.7.11.10.454
2oscMUHAngiopoietin-1 receptor2.7.10.10.454
2y60M8FIsopenicillin N synthase1.21.3.10.454
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.454
3e5aVX6Aurora kinase A2.7.11.10.454
3fl8RARDihydrofolate reductase/0.454
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.454
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.454
3ttjJBIMitogen-activated protein kinase 102.7.11.240.454
5k2aZMAAdenosine receptor A2a/0.454
1u4dDBQActivated CDC42 kinase 1/0.453
2vbdV10Isopenicillin N synthase1.21.3.10.453
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.453
3kpkFADSulfide-quinone reductase/0.453
3p6oETGCamphor 5-monooxygenase1.14.15.10.453
3tubFPUTyrosine-protein kinase SYK2.7.10.20.453
3vryB43Tyrosine-protein kinase HCK2.7.10.20.453
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.453
4nks2M2Fibroblast growth factor receptor 1/0.453
4wboANWRhodopsin kinase/0.453
5iu86DZAdenosine receptor A2a/0.453
1gqtACPRibokinase/0.452
1uzwCDHIsopenicillin N synthase1.21.3.10.452
2jb4A14Isopenicillin N synthase1.21.3.10.452
2p4yC03Peroxisome proliferator-activated receptor gamma/0.452
2q61SF1Peroxisome proliferator-activated receptor gamma/0.452
2q70DC8Estrogen receptor/0.452
3eta351Insulin receptor2.7.10.10.452
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.452
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.452
3t2yFADSulfide-quinone reductase/0.452
3tqhNDPQuinone oxidoreductase/0.452
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.452
4oavACP2-5A-dependent ribonuclease3.1.260.452
1cqp803Integrin alpha-L/0.451
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
1pjkANPCasein kinase II subunit alpha2.7.11.10.451
1rt4UC1Gag-Pol polyprotein2.7.7.490.451
1uy6PU3Heat shock protein HSP 90-alpha/0.451
2hasC3OVitamin D3 receptor/0.451
2hog710Serine/threonine-protein kinase Chk12.7.11.10.451
2po7CHDFerrochelatase, mitochondrial4.99.1.10.451
2uxoTACHTH-type transcriptional regulator TtgR/0.451
2vn0TDZCytochrome P450 2C8/0.451
2wotZZGTGF-beta receptor type-12.7.11.300.451
3clrFADElectron transfer flavoprotein subunit alpha/0.451
3cqeP91Wee1-like protein kinase2.7.10.20.451
3hllI45Mitogen-activated protein kinase 14/0.451
3r5zF42Uncharacterized protein/0.451
4b8mVX6Aurora kinase B-A2.7.11.10.451
4elg52JDihydrofolate reductase/0.451
4uyf73BBromodomain-containing protein 2/0.451
5cvfATPCasein kinase II subunit alpha2.7.11.10.451
5uviZMAAdenosine receptor A2a/0.451
1dajMOTDihydrofolate reductase1.5.1.30.450
1mc5AHEAlcohol dehydrogenase class-31.1.1.10.450
2cig1DGDihydrofolate reductase1.5.1.30.450
2wo7ASVIsopenicillin N synthase1.21.3.10.450
2z3uCRRCytochrome P450/0.450
3bfa9ODOdorant binding protein ASP1/0.450
3eej53RUncharacterized protein/0.450
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.450
3hz137DHeat shock protein HSP 90-alpha/0.450
4ag8AXIVascular endothelial growth factor receptor 22.7.10.10.450
4agcAXIVascular endothelial growth factor receptor 22.7.10.10.450
4fnyI3KALK tyrosine kinase receptor2.7.10.10.450
4j6dTESCytochrome P450 monooxygenase/0.450
4jq8KJ8Epidermal growth factor receptor2.7.10.10.450
4nmdFDABifunctional protein PutA/0.450
4wkqIREEpidermal growth factor receptor2.7.10.10.450
5iua6DXAdenosine receptor A2a/0.450
1ezfIN0Squalene synthase2.5.1.210.449
1kzjCB3Thymidylate synthase/0.449
1lriCLRBeta-elicitin cryptogein/0.449
2hcdBIVVitamin D3 receptor A/0.449
3icrCOACoenzyme A disulfide reductase/0.449
3icsCOACoenzyme A disulfide reductase/0.449
3p6nDSOCamphor 5-monooxygenase1.14.15.10.449
3t8xT8XT-cell surface glycoprotein CD1b/0.449
3vrtYS2Vitamin D3 receptor/0.449
3zoiM2WIsopenicillin N synthase1.21.3.10.449
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.449
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4hvh19RTyrosine-protein kinase JAK32.7.10.20.449
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.449
4uhrNGIAdenosine receptor A2a/0.449
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.448
1n4hREANuclear receptor ROR-beta/0.448
1sj0E4DEstrogen receptor/0.448
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.448
2fzhDH1Dihydrofolate reductase1.5.1.30.448
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.448
3ctj320Hepatocyte growth factor receptor2.7.10.10.448
3p6mDSOCamphor 5-monooxygenase1.14.15.10.448
3sls77DDual specificity mitogen-activated protein kinase kinase 12.7.12.20.448
3vrwYS5Vitamin D3 receptor/0.448
4alhA9PBromodomain-containing protein 2/0.448
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.448
4elb34RDihydrofolate reductase/0.448
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4iw8KN3Estrogen receptor/0.448
3emlZMAAdenosine receptor A2a/0.448
1e26GPBDihydrofolate reductase1.5.1.30.447
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1s6qTPBGag-Pol polyprotein2.7.7.490.447
1zg32HIIsoflavone 4'-O-methyltransferase/0.447
2bfpH4BPteridine reductase 11.5.1.330.447
2q59240Peroxisome proliferator-activated receptor gamma/0.447
2ydwWSHBromodomain-containing protein 2/0.447
2zevB71Geranylgeranyl pyrophosphate synthase/0.447
3cd2MTXDihydrofolate reductase1.5.1.30.447
3dhoB2MStreptogramin A acetyltransferase2.3.10.447
3kytHC2Nuclear receptor ROR-gamma/0.447
3tdaPN0Cytochrome P450 2D6/0.447
4a9mP9MBromodomain-containing protein 2/0.447
4j95ACPFibroblast growth factor receptor 2/0.447
4ku5DCC3-oxoacyl-[ACP] synthase III/0.447
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.447
5br4NADLactaldehyde reductase1.1.1.770.447
1di8DTQCyclin-dependent kinase 22.7.11.220.446
1fmlRTLRetinol dehydratase/0.446
1s1vTNKGag-Pol polyprotein2.7.7.490.446
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.446
2dr3ADPUPF0273 protein PH0284/0.446
2e9cB75Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.446
2hw2RFPRifampin ADP-ribosyl transferase/0.446
2iviACWIsopenicillin N synthase1.21.3.10.446
2qo9ANPEphrin type-A receptor 32.7.10.10.446
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.446
3ggfGVDSerine/threonine-protein kinase 26/0.446
3qlhT27Gag-Pol polyprotein2.7.7.490.446
3uoyNAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.446
3uvqFS8Mitogen-activated protein kinase 14/0.446
3vjoANPEpidermal growth factor receptor2.7.10.10.446
3vt9YI4Vitamin D3 receptor/0.446
3w2o03PEpidermal growth factor receptor2.7.10.10.446
4j4vSVRNucleocapsid protein/0.446
4jboWPHAurora kinase A2.7.11.10.446
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.446
4kaoKAOFocal adhesion kinase 12.7.10.20.446
4yuqKS1Calmodulin-like domain protein kinase/0.446
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.445
1uy9PU6Heat shock protein HSP 90-alpha/0.445
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.445
2izsBRQCasein kinase I isoform gamma-32.7.11.10.445
2ykiYKIHeat shock protein HSP 90-alpha/0.445
3anlNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.445
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.445
3eel53TUncharacterized protein/0.445
3oibFDAPutative acyl-CoA dehydrogenase/0.445
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.445
3vt5YI2Vitamin D3 receptor/0.445
4aotGW8Serine/threonine-protein kinase 102.7.11.10.445
4c4h7RODual specificity protein kinase TTK2.7.12.10.445
4c57FEFCyclin-G-associated kinase2.7.11.10.445
4e5yNDPGDP-L-fucose synthase1.1.1.2710.445
4elb34SDihydrofolate reductase/0.445
4fgh0U6Dihydrofolate reductase1.5.1.30.445
4h4o506Gag-Pol polyprotein2.7.7.490.445
4iaq2GM5-hydroxytryptamine receptor 1B/0.445
4ixeIXEDihydrofolate reductase1.5.1.30.445
4jx1CAMCamphor 5-monooxygenase1.14.15.10.445
4looSB4Mitogen-activated protein kinase 14/0.445
5aabVGHALK tyrosine kinase receptor2.7.10.10.445
1hvyD16Thymidylate synthase2.1.1.450.444
1ie4T44Transthyretin/0.444
1kyzFERCaffeic acid 3-O-methyltransferase2.1.1.680.444
1sqvUHDCytochrome b/0.444
2hb7O1CVitamin D3 receptor/0.444
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.444
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.444
3hub469Mitogen-activated protein kinase 14/0.444
3t9i3T9Serine/threonine-protein kinase pim-12.7.11.10.444
3tvuB37Acetyl-CoA carboxylase/0.444
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.444
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.444
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.444
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.444
4jqeANPCasein kinase II subunit alpha2.7.11.10.444
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.444
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.444
4tyj0LIFibroblast growth factor receptor 42.7.10.10.444
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.443
1m7aMQUDihydrofolate reductase1.5.1.30.443
1ppjSMACytochrome b/0.443
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.443
2hamC33Vitamin D3 receptor/0.443
2pz5ACPFibroblast growth factor receptor 2/0.443
2wouZZFTGF-beta receptor type-12.7.11.300.443
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3vquO22Dual specificity protein kinase TTK2.7.12.10.443
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.443
4ead0NPThymidine phosphorylase2.4.2.40.443
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.443
4g1z0VPVitamin D3 receptor A/0.443
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4h9614QDihydrofolate reductase1.5.1.30.443
4ia7BIVVitamin D3 receptor A/0.443
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.443
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
1jlaTNKGag-Pol polyprotein2.7.7.490.442
1k7l544Peroxisome proliferator-activated receptor alpha/0.442
1re9DSOCamphor 5-monooxygenase1.14.15.10.442
1s0zEB1Vitamin D3 receptor/0.442
1txtCAAHMG-CoA synthase/0.442
2agvTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.442
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.442
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
2excJNKMitogen-activated protein kinase 102.7.11.240.442
2wqbQQ1Angiopoietin-1 receptor2.7.10.10.442
2ykcYKCHeat shock protein HSP 90-alpha/0.442
3drcMTXDihydrofolate reductase1.5.1.30.442
3eem53VUncharacterized protein/0.442
3lf0ATPNitrogen regulatory protein P-II/0.442
3mnrSD1Heat shock protein HSP 90-alpha/0.442
3vt7VDXVitamin D3 receptor/0.442
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.442
4jqh1MFAlr2278 protein/0.442
4pkl1GHUncharacterized protein/0.442
4ruoBIVVitamin D3 receptor A/0.442
5k2cZMAAdenosine receptor A2a/0.442
1dr3HBIDihydrofolate reductase1.5.1.30.441
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1fp1HCCIsoliquiritigenin 2'-O-methyltransferase/0.441
1kyoSMACytochrome b/0.441
1pkfEPDEpothilone C/D epoxidase1.140.441
1rc1KT3Trifunctional purine biosynthetic protein adenosine-32.1.2.20.441
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
2aibERGBeta-elicitin cinnamomin/0.441
2c6hPXICytochrome P450 monooxygenase PikC/0.441
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2i9pNAD3-hydroxyisobutyrate dehydrogenase, mitochondrial1.1.1.310.441
2jblSMAReaction center protein L chain/0.441
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.441
2xa4AZ5Tyrosine-protein kinase JAK2/0.441
3abaFLICytochrome P450/0.441
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
3lu8IQXSerum albumin/0.441
3meeT27Gag-Pol polyprotein2.7.7.490.441
3njoPYVAbscisic acid receptor PYR1/0.441
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3vt8YI3Vitamin D3 receptor/0.441
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
3w5p4OAVitamin D3 receptor/0.441
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.441
4c4f7CEDual specificity protein kinase TTK2.7.12.10.441
4ez8DHFThymidylate synthase2.1.1.450.441
4fgg0U5Dihydrofolate reductase1.5.1.30.441
4fz60VGTyrosine-protein kinase SYK2.7.10.20.441
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.441
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.441
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.441
1fm9570Peroxisome proliferator-activated receptor gamma/0.440
1rkhVD2Vitamin D3 receptor/0.440
1tl3H20Gag-Pol polyprotein2.7.7.490.440
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.440
1xddAAYIntegrin alpha-L/0.440
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.440
2ylzFADPhenylacetone monooxygenase1.14.13.920.440
2yn8STUEphrin type-B receptor 42.7.10.10.440
2yxuATPPyridoxal kinase2.7.1.350.440
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.440
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.440
3iaeD7KBenzaldehyde lyase/0.440
3mdmFJZCholesterol 24-hydroxylase/0.440
3ol5SAWCamphor 5-monooxygenase1.14.15.10.440
3oquA8SAbscisic acid receptor PYL9/0.440
3qlxQLRUncharacterized protein/0.440
3s4qNK0Mitogen-activated protein kinase 14/0.440
3sz0FADSulfide-quinone reductase/0.440
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.440
3w33W19Epidermal growth factor receptor2.7.10.10.440
4a95NHWGlycylpeptide N-tetradecanoyltransferase/0.440
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4enhFVXCholesterol 24-hydroxylase/0.440
4i3wNADAldehyde dehydrogenase (NAD+)/0.440
5cvhADPCasein kinase II subunit alpha2.7.11.10.440