sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2fwn | TDP | Benzoylformate decarboxylase | 4.1.1.7 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2fwn | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 1.000 | |
| 1po7 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.798 | |
| 1bfd | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.748 | |
| 5dgt | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.748 | |
| 4ju8 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.736 | |
| 4qel | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.692 | |
| 4mq5 | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.670 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.666 | |
| 4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.642 | |
| 4ju9 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.640 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.636 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.634 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.628 | |
| 4gm4 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.627 | |
| 4jd5 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.620 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.606 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.606 | |
| 4gm0 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.597 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.589 | |
| 4mzx | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.587 | |
| 4juc | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.556 | |
| 4k9p | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.526 | |
| 4mpp | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.523 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.522 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.518 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.515 | |
| 2rc3 | NAD | CBS domain | / | 0.511 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.506 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.504 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.503 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.502 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.502 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.502 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.501 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.499 | |
| 3ieu | GDP | GTPase Era | / | 0.499 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.495 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.495 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.494 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.494 | |
| 3c8b | ARG_ARG_GLY_ILE_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.493 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.493 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.493 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.492 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.490 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.490 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.490 | |
| 1tys | TMP | Thymidylate synthase | / | 0.489 | |
| 1w5s | ADP | ORC1-type DNA replication protein 2 | / | 0.487 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.487 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.487 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.485 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.485 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.485 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.484 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.483 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.483 | |
| 2vhx | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.483 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.482 | |
| 4kqw | NAP | Ketol-acid reductoisomerase (NADP(+)) | / | 0.482 | |
| 3a3g | DLZ | Lumazine protein | / | 0.481 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.481 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.480 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.480 | |
| 4h1v | GNP | Dynamin-1-like protein | 3.6.5.5 | 0.480 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.480 | |
| 4irn | FAD | AnaB | / | 0.480 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.479 | |
| 2y4g | TIR | TamL | / | 0.479 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.479 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.479 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.478 | |
| 3fcj | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.478 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.478 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.477 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.477 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.477 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.477 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.477 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.477 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.476 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.476 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.476 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.475 | |
| 4fv1 | EK4 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.475 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.475 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.474 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.474 | |
| 2jih | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | 3.4.24 | 0.474 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.474 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.474 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.474 | |
| 5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.474 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.474 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.473 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.473 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.473 | |
| 3p8z | 36A | Genome polyprotein | 2.1.1.56 | 0.473 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.473 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.472 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.472 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.472 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.472 | |
| 2p41 | SAH | Genome polyprotein | / | 0.472 | |
| 3ge6 | FMN | Nitroreductase | / | 0.472 | |
| 3pfd | FDA | Acyl-CoA dehydrogenase FadE25 | / | 0.472 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.472 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.472 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.472 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.472 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.472 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.472 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.471 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.471 | |
| 3idb | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.471 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.470 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.470 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.470 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.470 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.470 | |
| 3mx5 | UTP | Nucleoprotein | / | 0.470 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.470 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.470 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.469 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.469 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.469 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.469 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.468 | |
| 1h6d | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.468 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.468 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.468 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.468 | |
| 2vhv | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.468 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.468 | |
| 4uz6 | SCR | Palmitoleoyl-protein carboxylesterase NOTUM | / | 0.468 | |
| 5aga | ANP | DNA polymerase theta | / | 0.468 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.467 | |
| 1ryd | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.467 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.467 | |
| 1z7e | UGA | Bifunctional polymyxin resistance protein ArnA | / | 0.467 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.467 | |
| 3f90 | FMN | Flavodoxin | / | 0.467 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.467 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.467 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.467 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.467 | |
| 3rdq | DTB | Streptavidin | / | 0.467 | |
| 3uoy | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.467 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.467 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.467 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.466 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.466 | |
| 3abx | RCB | Glucanase | / | 0.466 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.466 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.466 | |
| 5dbf | NDP | Iridoid synthase | 1.3.1.99 | 0.466 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.466 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.465 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.465 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.465 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.465 | |
| 3t7t | SAH | Uncharacterized protein | / | 0.465 | |
| 3wbz | ATP | tRNA(His) guanylyltransferase {ECO:0000256|PIRNR:PIRNR028980} | / | 0.465 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.465 | |
| 5ftf | ADP | TPR domain protein | / | 0.465 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.464 | |
| 4d5g | FAD | Cyclohexane-1,2-dione hydrolase | 3.7.1.11 | 0.464 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.464 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.464 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.463 | |
| 1rye | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.463 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.463 | |
| 2vhw | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.463 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.463 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.463 | |
| 4ctj | SAM | Genome polyprotein | / | 0.463 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.463 | |
| 4h12 | SAH | Histone-lysine N-methyltransferase SETD2 | 2.1.1.43 | 0.463 | |
| 4r39 | ANP | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.463 | |
| 5cfp | C2E | Stimulator of interferon genes protein | / | 0.463 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.463 | |
| 1h6b | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.462 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.462 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.462 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.462 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.462 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.462 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.462 | |
| 4eo3 | FMN | Bacterioferritin comigratory protein/NADH dehydrogenase | / | 0.462 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.462 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.462 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.462 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.462 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.461 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.461 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.461 | |
| 2ft0 | ACO | dTDP-fucosamine acetyltransferase | / | 0.461 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.461 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.461 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.461 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.461 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.461 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.461 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.461 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.461 | |
| 3zl8 | ADP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.461 | |
| 4ctk | SAM | Genome polyprotein | / | 0.461 | |
| 4gm1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.461 | |
| 4l7g | 1W0 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.460 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.460 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.460 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.460 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.460 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 4dja | FAD | (6-4) photolyase | / | 0.460 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.460 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.459 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.459 | |
| 3jsz | UPG | Uncharacterized protein | / | 0.459 | |
| 3jvv | ACP | Twitching mobility protein | / | 0.459 | |
| 3q1k | ADP | D-alanine--D-alanine ligase A | 6.3.2.4 | 0.459 | |
| 3u9e | COA | Lmo1369 protein | / | 0.459 | |
| 3wbf | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.459 | |
| 3x2w | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.459 | |
| 4i52 | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.459 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.459 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.458 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.458 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.458 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.458 | |
| 2wb2 | FAD | RE11660p | / | 0.458 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.458 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.458 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.458 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.458 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.458 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.458 | |
| 1c7o | PPG | Hemolysin | / | 0.457 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.457 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.457 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.457 | |
| 3ddn | HPV | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.457 | |
| 3ilt | TRU | Glutamate receptor 2 | / | 0.457 | |
| 3kyb | FMN | UDP-galactopyranose mutase | 5.4.99.9 | 0.457 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.457 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.457 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.457 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.457 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.457 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.457 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.456 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.456 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.456 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.456 | |
| 1x7d | NAD | Putative ornithine cyclodeaminase | / | 0.456 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.456 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.456 | |
| 2vhz | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.456 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 2vo6 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 3eld | SFG | Methyltransferase | / | 0.456 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3k5h | ATP | Phosphoribosyl-aminoimidazole carboxylase | / | 0.456 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.456 | |
| 3nl6 | ACP | Uncharacterized protein | / | 0.456 | |
| 3pxv | FMN | Nitroreductase | / | 0.456 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.456 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.456 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.456 | |
| 5bur | ATP | 2-succinylbenzoate--CoA ligase | / | 0.456 | |
| 5cts | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.456 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.456 | |
| 1la2 | NAD | Inositol-3-phosphate synthase | 5.5.1.4 | 0.455 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.455 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.455 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.455 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.455 | |
| 2vna | NAP | Prostaglandin reductase 2 | 1.3.1.48 | 0.455 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.455 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.455 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4fvq | ATP | Tyrosine-protein kinase JAK2 | / | 0.455 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.455 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.454 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.454 | |
| 2ge3 | ACO | Probable acetyltransferase | / | 0.454 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.454 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.454 | |
| 2xy3 | DUP | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.454 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3cwq | ADP | ParA family chromosome partitioning protein | / | 0.454 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.454 | |
| 3eof | FMN | Putative oxidase | / | 0.454 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.454 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.454 | |
| 3pi0 | F91 | Endothiapepsin | 3.4.23.22 | 0.454 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.454 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4hxy | NDP | Plm1 | / | 0.454 | |
| 4tl7 | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.454 | |
| 4y57 | F63 | Endothiapepsin | 3.4.23.22 | 0.454 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.454 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.454 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.453 | |
| 1yki | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.453 | |
| 2e16 | SAH | Diphthine synthase | / | 0.453 | |
| 2igy | A2T | Plasmepsin 2 | / | 0.453 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.453 | |
| 3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.453 | |
| 4e03 | ADP | Plasmid partitioning protein ParF | / | 0.453 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.453 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.453 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.453 | |
| 4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.453 | |
| 4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.453 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.453 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.453 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.453 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.452 | |
| 1h6a | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.452 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.452 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1ofg | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.452 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.452 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.452 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.452 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.452 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 3bnk | FMN | Flavoredoxin | / | 0.452 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.452 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.452 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.452 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.451 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.451 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.451 | |
| 1pl1 | ABY | Glutathione S-transferase A1 | 2.5.1.18 | 0.451 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.451 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.451 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.451 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.451 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.451 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.451 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.451 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.451 | |
| 3lu1 | UD2 | UDP-N-acetylglucosamine 4-epimerase | / | 0.451 | |
| 3vqh | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4fkz | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.451 | |
| 4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.451 | |
| 4rxq | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.451 | |
| 4tlz | NAP | KtzI | / | 0.451 | |
| 5ftc | ADP | TPR domain protein | / | 0.451 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.450 | |
| 1ds7 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.450 | |
| 1pox | TPP | Pyruvate oxidase | 1.2.3.3 | 0.450 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.450 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.450 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.450 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.450 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.450 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.450 | |
| 2rhq | GAX | Phenylalanine--tRNA ligase alpha subunit | / | 0.450 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.450 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.450 | |
| 3ckq | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.450 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.450 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 3ely | SAH | Methyltransferase | / | 0.450 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.450 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.450 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.450 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.450 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.449 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 2q14 | ADP | Phosphohydrolase | / | 0.449 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.449 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.449 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.449 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 3csc | ACO | Citrate synthase, mitochondrial | 2.3.3.1 | 0.449 | |
| 3mjh | GTP | Ras-related protein Rab-5A | / | 0.449 | |
| 3o3p | GDD | Glycosyl transferase, family 2 | / | 0.449 | |
| 3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.449 | |
| 3wsw | NAD | L-lactate dehydrogenase | / | 0.449 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.449 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.449 | |
| 4oaq | NDP | R-specific carbonyl reductase | / | 0.449 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.448 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.448 | |
| 1ppj | ANY | Cytochrome b | / | 0.448 | |
| 2e1z | B4P | Propionate kinase | / | 0.448 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.448 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.448 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2wtk | ANP | STE20-related kinase adapter protein alpha | / | 0.448 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3c9r | ATP | Thiamine-monophosphate kinase | / | 0.448 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.448 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.448 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.448 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.448 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.448 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.448 | |
| 4b0q | GMF | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4e2d | FMN | Dehydrogenase | / | 0.448 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.448 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.448 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.448 | |
| 4qtu | SAM | 18S rRNA (guanine(1575)-N(7))-methyltransferase | / | 0.448 | |
| 1got | GDP | Guanine nucleotide-binding protein G(t) subunit alpha-1 | / | 0.447 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.447 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.447 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.447 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.447 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.447 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.447 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.447 | |
| 3bac | 3B9 | DNA ligase | / | 0.447 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.447 | |
| 3bmo | NAP | Pteridine reductase | / | 0.447 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.447 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.447 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.447 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.447 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.447 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.447 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.447 | |
| 5dp2 | NAP | CurF | / | 0.447 | |
| 5ifi | PRX | Acetyl-coenzyme A synthetase | / | 0.447 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.446 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.446 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.446 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
| 1w48 | APC | NTPase P4 | / | 0.446 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.446 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2vtb | FAD | Cryptochrome DASH, chloroplastic/mitochondrial | / | 0.446 | |
| 2wq7 | FAD | RE11660p | / | 0.446 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.446 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.446 | |
| 3pju | C2E | Diguanylate cyclase/phosphodiesterase | / | 0.446 | |
| 3up5 | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.446 | |
| 4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.446 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.446 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.446 | |
| 5e7o | MGD | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.446 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.445 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.445 | |
| 1f20 | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.445 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.445 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.445 | |
| 1njf | ADP | DNA polymerase III subunit tau | 2.7.7.7 | 0.445 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.445 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.445 | |
| 2e93 | B29 | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 2g9u | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.445 | |
| 2j09 | FMN | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.445 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.445 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.445 | |
| 2x86 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.445 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.445 | |
| 3cso | XNI | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.445 | |
| 3dl0 | AP5 | Adenylate kinase | / | 0.445 | |
| 3eks | CY9 | Actin-5C | / | 0.445 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.445 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.445 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.445 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.445 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.445 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.445 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.445 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.445 | |
| 5a4v | QUE | Glutathione S-transferase F2 | 2.5.1.18 | 0.445 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.444 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.444 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.444 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.444 | |
| 1u7h | NAD | Putative ornithine cyclodeaminase | / | 0.444 | |
| 1xjq | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.444 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.444 | |
| 2gc8 | 885 | Polyprotein | / | 0.444 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.444 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.444 | |
| 2p6k | SAH | Diphthine synthase | / | 0.444 | |
| 2v00 | V15 | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 2wq6 | FAD | RE11660p | / | 0.444 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.444 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.444 | |
| 3c8a | ARG_ARG_GLY_LEU_NH2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.444 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.444 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.444 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.444 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.444 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.444 | |
| 4fgr | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 6.3.2.6 | 0.444 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 4tld | AGS | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.444 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.444 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.444 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.443 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.443 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.443 | |
| 1fml | RTL | Retinol dehydratase | / | 0.443 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.443 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.443 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.443 | |
| 1jq5 | NAD | Glycerol dehydrogenase | 1.1.1.6 | 0.443 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.443 | |
| 1n75 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.443 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.443 | |
| 1ylu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.443 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.443 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.443 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.443 | |
| 2nli | FMN | Lactate oxidase | / | 0.443 | |
| 2p2q | PRX | Acetyl-coenzyme A synthetase | / | 0.443 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.443 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 2v13 | C40 | Renin | 3.4.23.15 | 0.443 | |
| 2zue | ANP | Arginine--tRNA ligase | 6.1.1.19 | 0.443 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.443 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.443 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.443 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.443 | |
| 3ix3 | OHN | Transcriptional activator protein LasR | / | 0.443 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.443 | |
| 3tza | TZG | Glutamate receptor 2 | / | 0.443 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 4bls | APC | NTPase P4 | / | 0.443 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.443 | |
| 4l7j | 1W2 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.443 | |
| 4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.443 | |
| 4yp1 | 2BA | Stimulator of interferon genes protein | / | 0.443 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.443 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.442 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.442 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.442 | |
| 1e1c | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.442 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.442 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.442 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 1n2e | APC | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.442 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.442 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.442 | |
| 2ck3 | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.442 | |
| 2ck3 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 2qdx | FAD | Ferredoxin--NADP+ reductase | / | 0.442 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 2zr9 | DTP | Protein RecA | / | 0.442 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.442 | |
| 3c21 | 2BA | DNA integrity scanning protein DisA | / | 0.442 | |
| 3e39 | FMN | Nitroreductase | / | 0.442 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.442 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.442 | |
| 3mkh | FAD | Nitroalkane oxidase | / | 0.442 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3u4o | 08E | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.442 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.442 | |
| 5ahs | FAD | Acyl-CoA dehydrogenase | / | 0.442 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.441 | |
| 1iy8 | NAD | Levodione reductase | / | 0.441 | |
| 1jr8 | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.441 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.441 | |
| 1nvm | NAD | Acetaldehyde dehydrogenase | 1.2.1.10 | 0.441 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.441 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.441 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.441 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.441 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.441 | |
| 2q0k | NAP | Thioredoxin reductase | 1.8.1.9 | 0.441 | |
| 2q4w | FAD | Cytokinin dehydrogenase 7 | 1.5.99.12 | 0.441 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.441 | |
| 2vj6 | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.441 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.441 | |
| 3eku | CY9 | Actin-5C | / | 0.441 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.441 | |
| 3prs | RIT | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.441 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.441 | |
| 3x21 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.441 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.441 | |
| 4i4z | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.441 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.441 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.441 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.440 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.440 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 1q12 | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.440 | |
| 1q3q | ANP | Thermosome subunit alpha | / | 0.440 | |
| 1q51 | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.440 | |
| 1qzy | TDE | Methionine aminopeptidase 2 | / | 0.440 | |
| 1vso | AT1 | Glutamate receptor ionotropic, kainate 1 | / | 0.440 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1zsk | 421 | Coagulation factor XI | 3.4.21.27 | 0.440 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.440 | |
| 2eeq | SAH | Diphthine synthase | / | 0.440 | |
| 2eg5 | SAH | 7-methylxanthosine synthase 1 | / | 0.440 | |
| 2ez9 | TDK | Pyruvate oxidase | 1.2.3.3 | 0.440 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.440 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.440 | |
| 2gci | MRR | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.440 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.440 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.440 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.440 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.440 | |
| 2xbm | SAH | Genome polyprotein | / | 0.440 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.440 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.440 | |
| 3iaa | TYD | CalG2 | / | 0.440 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.440 | |
| 3kmy | D8Y | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3o7l | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 3rn8 | RN8 | Glutamate receptor 2 | / | 0.440 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 3t7s | SAM | Uncharacterized protein | / | 0.440 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.440 | |
| 3ut5 | LOC | Tubulin beta chain | / | 0.440 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4l7h | 1W1 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.440 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.440 | |
| 4qbf | AP5 | Adenylate kinase | / | 0.440 | |
| 4s26 | SAH | Phosphomethylpyrimidine synthase, chloroplastic | 4.1.99.17 | 0.440 | |
| 4wso | NAD | Probable nicotinate-nucleotide adenylyltransferase | / | 0.440 |