Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2foi | JPA | Enoyl-acyl carrier reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2foi | JPA | Enoyl-acyl carrier reductase | / | 1.000 | |
| 1nhg | TCL | Enoyl-ACP reductase | / | 0.736 | |
| 1nhw | TCC | Enoyl-ACP reductase | / | 0.706 | |
| 1zxl | JP1 | Enoyl-ACP reductase | / | 0.679 | |
| 2o2y | TCL | Enoyl-ACP reductase | / | 0.607 | |
| 1uh5 | TCL | Enoyl-ACP reductase | / | 0.602 | |
| 2op0 | 7PC | Enoyl-ACP reductase | / | 0.597 | |
| 3am3 | TCL | Enoyl-ACP reductase | / | 0.595 | |
| 3am4 | FT1 | Enoyl-ACP reductase | / | 0.595 | |
| 3f4b | TCL | Enoyl-acyl carrier protein reductase | / | 0.592 | |
| 1zsn | TN2 | Enoyl-ACP reductase | / | 0.591 | |
| 3lt2 | FT3 | Enoyl-ACP reductase | / | 0.591 | |
| 3lsy | FT0 | Enoyl-ACP reductase | / | 0.583 | |
| 1nnu | TCT | Enoyl-ACP reductase | / | 0.582 | |
| 3lt0 | FT1 | Enoyl-ACP reductase | / | 0.582 | |
| 4ige | CHJ | Enoyl-acyl carrier reductase | / | 0.578 | |
| 3am5 | TCL | Enoyl-ACP reductase | / | 0.576 | |
| 1zw1 | TN5 | Enoyl-ACP reductase | / | 0.573 | |
| 2ol4 | JPN | Enoyl-ACP reductase | / | 0.573 | |
| 3lt1 | FT2 | Enoyl-ACP reductase | / | 0.573 | |
| 2o2s | TCL | Enoyl-acyl carrier reductase | / | 0.546 | |
| 5coq | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.527 | |
| 3fnh | JPJ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.507 | |
| 3nrc | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.499 | |
| 1kce | CB3 | Thymidylate synthase | / | 0.496 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.496 | |
| 3nj8 | NJ8 | Enoyl-acyl carrier reductase | / | 0.495 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.495 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.493 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.491 | |
| 1svg | I04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.490 | |
| 4qkn | JMS | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.490 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.488 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.487 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.486 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.485 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.484 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.482 | |
| 3fne | 8PC | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.482 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.481 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.481 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.480 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.479 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.478 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.477 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.477 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.477 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.477 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.477 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.476 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.476 | |
| 1ppj | ANY | Cytochrome b | / | 0.475 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.475 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.473 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.472 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.472 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.472 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.471 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.471 | |
| 1hk5 | T44 | Serum albumin | / | 0.470 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.470 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.470 | |
| 2bxm | IMN | Serum albumin | / | 0.469 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.469 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.469 | |
| 1hqt | NAP | Alcohol dehydrogenase [NADP(+)] | 1.1.1.2 | 0.468 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.468 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.468 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 4qo9 | 627 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.468 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.468 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.467 | |
| 3mqe | 416 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.467 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.467 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.467 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.467 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.467 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.466 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.466 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.466 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.465 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.465 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.465 | |
| 4ubu | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.465 | |
| 1qvn | FRI | Interleukin-2 | / | 0.464 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.464 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.464 | |
| 3b9l | AZZ | Serum albumin | / | 0.464 | |
| 3bhh | 5CP | Calcium/calmodulin-dependent protein kinase type II subunit beta | 2.7.11.17 | 0.464 | |
| 3gg0 | FMN | Uncharacterized protein | / | 0.464 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.464 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.464 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.464 | |
| 5kcp | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.464 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.463 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.463 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.463 | |
| 4e20 | 0MY | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.463 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.462 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.462 | |
| 4ng5 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.462 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.461 | |
| 2jdv | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.461 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.461 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.461 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.461 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.460 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.460 | |
| 2vqo | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.460 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.460 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.459 | |
| 1jx0 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.459 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.459 | |
| 3u5s | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.459 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.459 | |
| 3znp | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.459 | |
| 4f08 | 1RS | Tyrosine-protein kinase JAK2 | / | 0.459 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.459 | |
| 4inb | 1F6 | Gag protein | / | 0.459 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.458 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.458 | |
| 3ezv | EZV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.458 | |
| 4dru | 0LN | Genome polyprotein | 2.7.7.48 | 0.458 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.458 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.457 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.457 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.457 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.457 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.457 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 1z1f | STL | Resveratrol synthase | / | 0.456 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.456 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.456 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.456 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.456 | |
| 5byl | GCP | Bifunctional AAC/APH | 2.3.1 | 0.456 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.455 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.455 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.455 | |
| 3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.455 | |
| 4mr6 | 1K0 | Bromodomain-containing protein 2 | / | 0.455 | |
| 4qny | ANP | Mitogen activated protein kinase, putative | / | 0.455 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.454 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.454 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.454 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.454 | |
| 2uw6 | GVO | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 3qtu | X44 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.454 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 4xzm | NAP | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.454 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.454 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.454 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.453 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.453 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 3dl0 | AP5 | Adenylate kinase | / | 0.453 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.453 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.453 | |
| 2mm3 | CHO | Gastrotropin | / | 0.452 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.452 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.452 | |
| 4mlh | VO2 | Glucokinase | 2.7.1.2 | 0.452 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.452 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.452 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.451 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.451 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.451 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.451 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.451 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.451 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.451 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.451 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.451 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.450 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.450 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.450 | |
| 2wsa | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.450 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.450 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.450 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.450 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.450 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.450 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.450 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.450 | |
| 4xwt | U5P | Ribonuclease J | / | 0.450 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.449 | |
| 1eio | GCH | Gastrotropin | / | 0.449 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.449 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.449 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.449 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.449 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.449 | |
| 3q0u | LL3 | HTH-type transcriptional regulator EthR | / | 0.449 | |
| 3stw | 2TD | Methylketone synthase I | / | 0.449 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.449 | |
| 4rrx | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.449 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.448 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.448 | |
| 2iyi | FMN | AppA, antirepressor of ppsR, sensor of blue light | / | 0.448 | |
| 2xaa | NAD | Secondary alcohol dehydrogenase | / | 0.448 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.448 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.448 | |
| 3lpf | Z77 | Beta-glucuronidase | 3.2.1.31 | 0.448 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.448 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.448 | |
| 4acm | 7YG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4e0i | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.448 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.448 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 4v12 | POG | MaoC like domain protein | / | 0.448 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.448 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.447 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.447 | |
| 2qd9 | LGF | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.447 | |
| 4a4z | ANP | Antiviral helicase SKI2 | 3.6.4.13 | 0.447 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.447 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.447 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.447 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.447 | |
| 4ix4 | ADP | Uncharacterized protein | / | 0.447 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4kcf | AKM | FAD-dependent oxidoreductase | / | 0.447 | |
| 4kfp | 1R7 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.447 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.447 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.447 | |
| 4p13 | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
| 4tyq | AP5 | Adenylate kinase | / | 0.447 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.447 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.446 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.446 | |
| 1rkd | ADP | Ribokinase | / | 0.446 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 2huq | SAH | Diphthine synthase | / | 0.446 | |
| 2nsd | 4PI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.446 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.446 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.446 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.446 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.446 | |
| 4e6q | 0NV | Tyrosine-protein kinase JAK2 | / | 0.446 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 4yut | FMN | Family 3 adenylate cyclase | / | 0.446 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 1ozh | HE3 | Acetolactate synthase, catabolic | 2.2.1.6 | 0.445 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.445 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.445 | |
| 2a5y | ATP | Cell death protein 4 | / | 0.445 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.445 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.445 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.445 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.445 | |
| 3roy | 22Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4a2z | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.445 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.445 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.445 | |
| 4o95 | 245 | Cytokinin dehydrogenase 4 | / | 0.445 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.445 | |
| 4rrw | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.445 | |
| 4rrz | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.445 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.445 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.444 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.444 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.444 | |
| 2bxq | IMN | Serum albumin | / | 0.444 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.444 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.444 | |
| 2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.444 | |
| 3iaa | TYD | CalG2 | / | 0.444 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.444 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.444 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.444 | |
| 3tk0 | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.444 | |
| 3up0 | D7S | aceDAF-12 | / | 0.444 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.444 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4xye | NAD | Formate dehydrogenase | / | 0.444 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.444 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.443 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.443 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1qax | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.443 | |
| 1rej | B1L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 1sm2 | STU | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.443 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.443 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.443 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 4a32 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4bbh | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4c2z | MYA | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.443 | |
| 4deg | 0JJ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.443 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.443 | |
| 4ivc | 1J6 | Tyrosine-protein kinase JAK1 | / | 0.443 | |
| 4ma6 | 28E | Ara h 8 allergen | / | 0.443 | |
| 5kcp | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1flm | FMN | FMN-binding protein | / | 0.442 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.442 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1ikv | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1sny | NAP | LD36273p | / | 0.442 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.442 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.442 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.442 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.442 | |
| 3nf4 | FAD | Acyl-CoA dehydrogenase domain-containing protein | / | 0.442 | |
| 3ukr | CKH | Actin-related protein 3 | / | 0.442 | |
| 3ukr | CKH | Actin-related protein 2 | / | 0.442 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.442 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.442 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 4nr5 | 2LL | CREB-binding protein | / | 0.442 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.442 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.442 | |
| 5kj6 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.441 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.441 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1nq2 | 4HY | Thyroid hormone receptor beta | / | 0.441 | |
| 1stc | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 2j9m | PY8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2r3i | SCF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2uzd | C85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 3bhr | THG | Thymidylate synthase | / | 0.441 | |
| 3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.441 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3rpo | 24Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.441 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.441 | |
| 3tp0 | FO5 | HTH-type transcriptional regulator EthR | / | 0.441 | |
| 4c59 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.441 | |
| 4ehz | JAK | Tyrosine-protein kinase JAK1 | / | 0.441 | |
| 4fk6 | 0UJ | Tyrosine-protein kinase JAK1 | / | 0.441 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.441 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.441 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.441 | |
| 4o0w | ADN | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4rrq | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.441 | |
| 5aaa | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.441 | |
| 5cdt | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 6upj | NIU | Gag-Pol polyprotein | / | 0.441 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1d7o | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.440 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.440 | |
| 1pyx | ANP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.440 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.440 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.440 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.440 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.440 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.440 | |
| 3zsw | ZSW | Integrase | / | 0.440 | |
| 4bz7 | B3N | Histone deacetylase | / | 0.440 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.440 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.440 | |
| 4ork | GDP | Bifunctional AAC/APH | 2.3.1 | 0.440 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.440 | |
| 4xd2 | NAI | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 4xzn | NAP | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.440 |