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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2fl2ADPKinesin-like protein KIF11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2fl2ADPKinesin-like protein KIF11/1.000
2q2yADPKinesin-like protein KIF11/0.550
3l3rOAGDihydrofolate reductase1.5.1.30.514
2vbdV10Isopenicillin N synthase1.21.3.10.512
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.506
2jb4A14Isopenicillin N synthase1.21.3.10.502
1c7oPPGHemolysin/0.498
3zoiM2WIsopenicillin N synthase1.21.3.10.494
4q71FADBifunctional protein PutA/0.492
4bftZVTPantothenate kinase2.7.1.330.491
1hb3SCVIsopenicillin N synthase1.21.3.10.490
2dhfDZFDihydrofolate reductase1.5.1.30.489
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.489
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.488
2wo7ASVIsopenicillin N synthase1.21.3.10.488
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.488
1pd9CO4Dihydrofolate reductase1.5.1.30.487
1xzqFONtRNA modification GTPase MnmE3.6.50.487
1fmjRTLRetinol dehydratase/0.486
5ej4TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.486
1mvtDTMDihydrofolate reductase1.5.1.30.485
2pg2ADPKinesin-like protein KIF11/0.485
2z4sADPChromosomal replication initiator protein DnaA/0.485
2g8yNADHydroxycarboxylate dehydrogenase B/0.484
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.484
3tfyCOAN-alpha-acetyltransferase 502.3.10.484
1ra3NAPDihydrofolate reductase1.5.1.30.483
1w76GNTAcetylcholinesterase3.1.1.70.483
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.483
2iviACWIsopenicillin N synthase1.21.3.10.483
3pqbVGPPutative oxidoreductase/0.483
1pqc444Oxysterols receptor LXR-beta/0.482
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.482
4eiyZMAAdenosine receptor A2a/0.481
1blzACVIsopenicillin N synthase1.21.3.10.479
1o04NADAldehyde dehydrogenase, mitochondrial1.2.1.30.479
2bu9HFVIsopenicillin N synthase1.21.3.10.479
2xaeADPKinesin-like protein KIF11/0.479
3wv9FEGHmd co-occurring protein HcgE/0.479
2ejzSAHDiphthine synthase/0.478
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.478
4p9dTMPDeoxycytidylate deaminase/0.478
1icpFMN12-oxophytodienoate reductase 11.3.1.420.477
3l9hADPKinesin-like protein KIF11/0.477
1obnASVIsopenicillin N synthase1.21.3.10.476
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.476
3qm4PN0Cytochrome P450 2D6/0.476
1qiqACCIsopenicillin N synthase1.21.3.10.475
1u1d181Uridine phosphorylase2.4.2.30.475
1ygjRMCPyridoxal kinase2.7.1.350.475
4rp8ASCAscorbate-specific PTS system EIIC component/0.475
4mqt2CUMuscarinic acetylcholine receptor M2/0.475
4mlp2CXCryptochrome-2/0.474
1hb1OCVIsopenicillin N synthase1.21.3.10.473
2vbpVB1Isopenicillin N synthase1.21.3.10.473
1kqfMGDFormate dehydrogenase, nitrate-inducible, major subunit1.1.5.60.472
2ym2NAPPhenylacetone monooxygenase1.14.13.920.472
3fvqATPFe(3+) ions import ATP-binding protein FbpC/0.472
4i1nFOLDihydrofolate reductase1.5.1.30.472
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.472
2rs1W84Genome polyprotein/0.471
3rsv3RSBeta-secretase 13.4.23.460.471
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.471
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.471
1bk0ACVIsopenicillin N synthase1.21.3.10.470
1drfFOLDihydrofolate reductase1.5.1.30.470
2a4nCOAAac(6')-Ii protein/0.470
2rm2W43Genome polyprotein/0.470
2j3qTFLAcetylcholinesterase3.1.1.70.469
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.469
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.469
1stdBFSScytalone dehydratase4.2.1.940.468
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.468
4kovKOVUncharacterized protein/0.468
1qjfACSIsopenicillin N synthase1.21.3.10.467
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.467
2z3uCRRCytochrome P450/0.467
3hwxTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.467
3juqAKDPhenazine biosynthesis protein A/B/0.467
3tdaPN0Cytochrome P450 2D6/0.467
4n4v2GYTankyrase-12.4.2.300.467
1v35NAIEnoyl-ACP reductase/0.466
1vbiNADMalate/L-lactate dehydrogenase family protein/0.466
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.466
4xba5GPAprataxin-like protein30.466
4yaoFMNNADPH--cytochrome P450 reductase/0.466
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.466
1diuBDMDihydrofolate reductase1.5.1.30.465
1yrsADPKinesin-like protein KIF11/0.465
2cekN8TAcetylcholinesterase3.1.1.70.465
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.465
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
4bfxZVXPantothenate kinase2.7.1.330.465
4dk70KSOxysterols receptor LXR-beta/0.465
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.465
5ej6TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.465
5iua6DXAdenosine receptor A2a/0.465
1pq944BOxysterols receptor LXR-beta/0.464
1w06W05Isopenicillin N synthase1.21.3.10.464
2pauD5M5'-deoxynucleotidase YfbR/0.464
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
4ao4PLKBeta-transaminase/0.464
4bb3KKAIsopenicillin N synthase1.21.3.10.464
5k2bZMAAdenosine receptor A2a/0.464
1t4v14AProthrombin3.4.21.50.463
1u1f183Uridine phosphorylase2.4.2.30.463
1u65CP0Acetylcholinesterase3.1.1.70.463
2ewaSB2Mitogen-activated protein kinase 14/0.463
2rlcCHDCholoylglycine hydrolase3.5.1.240.463
2w3mFOLDihydrofolate reductase1.5.1.30.463
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
3pefNAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase/0.463
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.463
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.463
4b4w9L9Bifunctional protein FolD/0.463
4pnmNU1Tankyrase-22.4.2.300.463
4x5iFOLDihydrofolate reductase1.5.1.30.463
1bwkFMNNADPH dehydrogenase 11.6.99.10.462
1xs7MMIBeta-secretase 13.4.23.460.462
1y9dTPPPyruvate oxidase1.2.3.30.462
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.462
2oo5TXDNAD(P) transhydrogenase subunit alpha part 11.6.1.20.462
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3p67FMNPentaerythritol tetranitrate reductase/0.462
3q44D50M1 family aminopeptidase3.4.110.462
3up0D7SaceDAF-12/0.462
4bfuZVUPantothenate kinase2.7.1.330.462
4h0vNADIota toxin component Ia/0.462
1ascNPLAspartate aminotransferase2.6.1.10.461
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.461
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.461
1s7gNADNAD-dependent protein deacylase 2/0.461
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.461
4koxCLSUncharacterized protein/0.461
5stdUNNScytalone dehydratase4.2.1.940.461
1dyjDDFDihydrofolate reductase1.5.1.30.460
1zdwFLVPrenyltransferase/0.460
2e0nSAHPrecorrin-2 C20-methyltransferase/0.460
2wvlGDDMannosyl-3-phosphogylcerate synthase/0.460
2ydoADNAdenosine receptor A2a/0.460
3hgrFMN12-oxophytodienoate reductase 11.3.1.420.460
4m2bUPGUDP-glucose pyrophosphorylase/0.460
4rvgTYDD-mycarose 3-C-methyltransferase/0.460
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.460
1dliUDXUDP-glucose 6-dehydrogenase/0.459
2yoj8Y6Genome polyprotein2.7.7.480.459
3eksCY9Actin-5C/0.459
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.459
3gwdNAPCyclohexanone monooxygenase/0.459
3p0fBAUUridine phosphorylase 22.4.2.30.459
4a83DXCMajor pollen allergen Bet v 1-A/0.459
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.459
4fflADPUncharacterized protein/0.459
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.459
5esdTDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.459
1txtCAAHMG-CoA synthase/0.458
1w6rGNTAcetylcholinesterase3.1.1.70.458
3zm5IGMUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.458
4fhpUTPTerminal uridylyltransferase cid1/0.458
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.458
1adfTADAlcohol dehydrogenase E chain1.1.1.10.457
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
1opbRETRetinol-binding protein 2/0.457
2abbFMNPentaerythritol tetranitrate reductase/0.457
2am22LGUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.457
2jlcTPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.457
3jynNDPQuinone oxidoreductase/0.457
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.457
1cq7PY5Aspartate aminotransferase2.6.1.10.456
1dhfFOLDihydrofolate reductase1.5.1.30.456
1h50FMNPentaerythritol tetranitrate reductase/0.456
1n08ADPRiboflavin kinase2.7.1.260.456
1zgaHMKIsoflavone 4'-O-methyltransferase/0.456
2bfaCB3Pteridine reductase 11.5.1.330.456
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.456
2v5aLZLBiotin carboxylase6.3.4.140.456
2xuoTZ4Acetylcholinesterase3.1.1.70.456
2y60M8FIsopenicillin N synthase1.21.3.10.456
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.456
3n19FNRXenobiotic reductase/0.456
3v76FDAUncharacterized protein/0.456
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.456
4i4z2NE1,4-dihydroxy-2-naphthoyl-CoA synthase/0.456
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.456
1o5gCR9Prothrombin3.4.21.50.455
1o6qR17Squalene--hopene cyclase4.2.1.1290.455
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.455
2zsdCOAPantothenate kinase2.7.1.330.455
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.455
3c1y2BADNA integrity scanning protein DisA/0.455
3qwc98PProthrombin3.4.21.50.455
3tl1JROPutative polyketide cyclase/0.455
3zkyWT4Isopenicillin N synthase1.21.3.10.455
4a81DXCMajor pollen allergen Bet v 1-A/0.455
4bfvZVVPantothenate kinase2.7.1.330.455
4k7yFMNNADPH dehydrogenase 11.6.99.10.455
4kbyC2EStimulator of interferon genes protein/0.455
4l9q9TPSerum albumin/0.455
4rkdKETAminotransferase/0.455
8catNDPCatalase1.11.1.60.455
1disBDMDihydrofolate reductase1.5.1.30.454
1oc1ASVIsopenicillin N synthase1.21.3.10.454
2bfpH4BPteridine reductase 11.5.1.330.454
2bsxNOSPurine nucleoside phosphorylase/0.454
2iyaZIOOleandomycin glycosyltransferase/0.454
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
2p2xSAHDiphthine synthase/0.454
3adaNADSubunit alpha of sarocosine oxidase/0.454
3c1oNAPEugenol synthase/0.454
3h4vDVPPteridine reductase 11.5.1.330.454
4nv10FXFormyl transferase/0.454
5agyGTBTau class glutathione S-transferase/0.454
5iu86DZAdenosine receptor A2a/0.454
1b9iPXG3-amino-5-hydroxybenzoate synthase4.2.1.1440.453
1cqp803Integrin alpha-L/0.453
1ex75GPGuanylate kinase2.7.4.80.453
1kbjFMNCytochrome b2, mitochondrial1.1.2.30.453
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
1u1gBBBUridine phosphorylase2.4.2.30.453
1w29TS06,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.453
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.453
3ft8MOJHeat shock protein HSP 90-alpha/0.453
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.453
3isjA8DPantothenate synthetase6.3.2.10.453
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.453
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.453
4i13FOLDihydrofolate reductase1.5.1.30.453
4v12POGMaoC like domain protein/0.453
1c4yIH3Prothrombin3.4.21.50.452
1gj5130Prothrombin3.4.21.50.452
1qtiGNTAcetylcholinesterase3.1.1.70.452
1rp7TZDPyruvate dehydrogenase E1 component1.2.4.10.452
1ykdCMPAdenylate cyclase/0.452
2uuk897Prothrombin3.4.21.50.452
2xugTZ4Acetylcholinesterase3.1.1.70.452
2y6fM9FIsopenicillin N synthase1.21.3.10.452
3bgxMEFThymidylate synthase/0.452
3n0hTOPDihydrofolate reductase1.5.1.30.452
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.452
3vkjFNRIsopentenyl-diphosphate delta-isomerase/0.452
4hy6FJ1Heat shock protein HSP 90-alpha/0.452
4uugPXGBranched-chain amino acid aminotransferase, putative/0.452
5irnADPNucleotide binding oligomerization domain containing 2/0.452
1nghATPHeat shock cognate 71 kDa protein/0.451
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.451
1uzwCDHIsopenicillin N synthase1.21.3.10.451
1x1dSAHC-20 methyltransferase/0.451
2j6xFMNLactate oxidase/0.451
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.451
3bi6396Wee1-like protein kinase2.7.10.20.451
3biz61EWee1-like protein kinase2.7.10.20.451
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.451
4qx5CMPcGMP-dependent protein kinase 12.7.11.120.451
4tx9AMZPhosphoribosyl isomerase A/0.451
5ej9TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.451
1ek5NADUDP-glucose 4-epimerase/0.450
1kqgMGDFormate dehydrogenase, nitrate-inducible, major subunit1.1.5.60.450
1n06ADPRiboflavin kinase2.7.1.260.450
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.450
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.450
1r8qAFBCytohesin-2/0.450
1r8qAFBADP-ribosylation factor 1/0.450
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.450
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.450
2acwUPGGlycosyltransferase/0.450
2cvzNDP3-hydroxyisobutyrate dehydrogenase/0.450
2j9lATPH(+)/Cl(-) exchange transporter 5/0.450
2rr1W8RGenome polyprotein/0.450
2vcmM11Isopenicillin N synthase1.21.3.10.450
3dr7GPDGDP-perosamine synthase/0.450
3h2sNDPPutative NADH-flavin reductase/0.450
3s3vTOPDihydrofolate reductase1.5.1.30.450
4jq3NAPAldo-keto reductase family 1 member C2/0.450
5dozNDPJamJ/0.450
2dvlFADAcyl-CoA dehydrogenase/0.449
2pbwDOQGlutamate receptor ionotropic, kainate 1/0.449
2pswCOAN-alpha-acetyltransferase 50/0.449
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.449
2xvfFADPutative flavin-containing monooxygenase/0.449
3b1pNOSPfkB carbohydrate kinase family protein/0.449
3e6eDCSAlanine racemase/0.449
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.449
3gyf51PDihydrofolate reductase1.5.1.30.449
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.449
3tm5SFGUncharacterized protein/0.449
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.449
4k30NLGN-acetylglutamate synthase, mitochondrial2.3.1.10.449
4kowCFXUncharacterized protein/0.449
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.449
4o671SYCyclic GMP-AMP synthase/0.449
4xnw2IDP2Y purinoceptor 1/0.449
1g6oADPCag alpha/0.448
1h36R88Squalene--hopene cyclase4.2.1.1290.448
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.448
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2e15SAHDiphthine synthase/0.448
2fb35ADGTP 3',8-cyclase4.1.99.180.448
2g1s4IGRenin3.4.23.150.448
2on6IMHPurine nucleoside phosphorylase2.4.2.10.448
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
2r6gATPMaltose/maltodextrin import ATP-binding protein MalK/0.448
2wwjY28Lysine-specific demethylase 4A/0.448
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.448
3atzFMNProstaglandin F2a synthase/0.448
3bv2P38Mitogen-activated protein kinase 14/0.448
3pahXDEPhenylalanine-4-hydroxylase1.14.16.10.448
4a86H35Major pollen allergen Bet v 1-A/0.448
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.448
5dn1AMZPhosphoribosyl isomerase A5.3.1.160.448
5pahLDPPhenylalanine-4-hydroxylase1.14.16.10.448
1beuIPLTryptophan synthase alpha chain/0.447
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.447
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.447
2cjfRP43-dehydroquinate dehydratase4.2.1.100.447
2dv5SAHDiphthine synthase/0.447
2e07SAHDiphthine synthase/0.447
2ji6ADPOxalyl-CoA decarboxylase4.1.1.80.447
2ob0ACON-alpha-acetyltransferase 50/0.447
2q59240Peroxisome proliferator-activated receptor gamma/0.447
2vczVC3Hematopoietic prostaglandin D synthase/0.447
2x7hPFNProstaglandin reductase 310.447
2xpc051UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.447
2zfq45UProthrombin3.4.21.50.447
2zi63D1Deoxycytidine kinase2.7.1.740.447
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.447
3p62FMNPentaerythritol tetranitrate reductase/0.447
3p74FMNPentaerythritol tetranitrate reductase/0.447
3slkNDPPolyketide synthase extender module 2/0.447
3tvqDQHMultifunctional cyclase-dehydratase-3-O-methyl transferase TcmN2.1.10.447
3zeiAWHO-acetylserine sulfhydrylase/0.447
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4df2FMNNADPH dehydrogenase/0.447
4iarERM5-hydroxytryptamine receptor 1B/0.447
5cxxFERFae1A/0.447
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.446
1e2nRCAThymidine kinase/0.446
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.446
1g8oU5PN-acetyllactosaminide alpha-1,3-galactosyltransferase/0.446
1h51FMNPentaerythritol tetranitrate reductase/0.446
1rd4L08Integrin alpha-L/0.446
1s3uTQDDihydrofolate reductase1.5.1.30.446
1vkgCRIHistone deacetylase 83.5.1.980.446
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.446
1y1rANUUridine phosphorylase2.4.2.30.446
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
2hpsCTZCa2+-triggered coelenterazine-binding protein 1/0.446
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.446
2zryFNRIsopentenyl-diphosphate delta-isomerase/0.446
3c35KAIGlutamate receptor ionotropic, kainate 1/0.446
3hkwIX6Genome polyprotein2.7.7.480.446
3hqdANPKinesin-like protein KIF11/0.446
3ijdC2FMethylenetetrahydrofolate reductase/0.446
3m67E36Carbonic anhydrase 24.2.1.10.446
3x0a5GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.446
4awsFMNNADH:flavin oxidoreductase Sye1/0.446
5uviZMAAdenosine receptor A2a/0.446
1cbrREACellular retinoic acid-binding protein 1/0.445
1dx6GNTAcetylcholinesterase3.1.1.70.445
1e92HBIPteridine reductase 11.5.1.330.445
1h63FMNPentaerythritol tetranitrate reductase/0.445
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.445
1vf2GTXGlutathione S-transferase 32.5.1.180.445
1w1wAGSStructural maintenance of chromosomes protein 1/0.445
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.445
2bf7HBIPteridine reductase 11.5.1.330.445
2pg0FADAcyl-CoA dehydrogenase/0.445
2vd7PD2Lysine-specific demethylase 4A1.14.110.445
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
2zevB71Geranylgeranyl pyrophosphate synthase/0.445
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
3p9tTCLRepressor/0.445
3tzaTZGGlutamate receptor 2/0.445
3u4o08EGenome polyprotein2.7.7.480.445
4e0u0MVCyclic dipeptide N-prenyltransferase/0.445
4h6uACOAlpha-tubulin N-acetyltransferase 1/0.445
4lzwTHMUridine phosphorylase/0.445
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
4ybnFADFlavin-nucleotide-binding protein/0.445
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.444
1crbRTLRetinol-binding protein 1/0.444
1gpnHUBAcetylcholinesterase3.1.1.70.444
1w4lGL8Acetylcholinesterase3.1.1.70.444
1zgv501Prothrombin3.4.21.50.444
2e20B4PPropionate kinase/0.444
2g78REACellular retinoic acid-binding protein 2/0.444
2gsqGBIGlutathione S-transferase2.5.1.180.444
2x19GTPGTP-binding nuclear protein GSP1/CNR1/0.444
3gkjHC3Niemann-Pick C1 protein/0.444
3hnaSAHHistone-lysine N-methyltransferase EHMT1/0.444
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.444
3x04GNPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.444
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.444
4guuFA9Lysine-specific histone demethylase 1B10.444
5ej7TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.444
5esoTDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.444
1bzfTMQDihydrofolate reductase1.5.1.30.443
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.443
1ve3SAMUncharacterized protein/0.443
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2clmF6FTryptophan synthase alpha chain/0.443
2e7rSAHDiphthine synthase/0.443
2eeqSAHDiphthine synthase/0.443
2iegFRYGlycogen phosphorylase, muscle form2.4.1.10.443
2ji7ADPOxalyl-CoA decarboxylase4.1.1.80.443
2qimZEAClass 10 plant pathogenesis-related protein/0.443
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.443
2zrvFNRIsopentenyl-diphosphate delta-isomerase/0.443
3ekuCY9Actin-5C/0.443
3frfXCFDihydrofolate reductase1.5.1.30.443
3fzfATPHeat shock cognate 71 kDa protein/0.443
3hu1AGSTransitional endoplasmic reticulum ATPase3.6.4.60.443
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3q9bB3NAcetylpolyamine amidohydrolase/0.443
3swcSAHHistone-lysine N-methyltransferase EHMT1/0.443
3vv8B02Beta-secretase 13.4.23.460.443
3zbzOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
4a87NARMajor pollen allergen Bet v 1-A/0.443
4aoaIK2Beta-phenylalanine transaminase2.6.10.443
4kq1U5PGlycogen [starch] synthase/0.443
5d3qGDPDynamin-13.6.5.50.443
1dhjMTXDihydrofolate reductase1.5.1.30.442
1dljUGAUDP-glucose 6-dehydrogenase/0.442
1nm6L86Prothrombin3.4.21.50.442
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.442
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.442
1uydPU8Heat shock protein HSP 90-alpha/0.442
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.442
2e77FMNLactate oxidase/0.442
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.442
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2imkGTXAGAP009194-PA/0.442
2ozrGG1Collagenase 33.4.240.442
2rgjFADFlavin-containing monooxygenase/0.442
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.442
3bl7DD1m7GpppX diphosphatase3.6.1.590.442
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.442
3l0lHC3Nuclear receptor ROR-gamma/0.442
3qe2FMNNADPH--cytochrome P450 reductase/0.442
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3w6uNAP6-phosphogluconate dehydrogenase, NAD-binding protein/0.442
3zbrNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4c49HCYCorticosteroid-binding globulin/0.442
4kouC04Uncharacterized protein/0.442
4mkb28VGenome polyprotein2.7.7.480.442
4q73FADBifunctional protein PutA/0.442
5d4vYGPUncharacterized protein MJ0489/0.442
1aqv0HGGlutathione S-transferase P2.5.1.180.441
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.441
1d3pBT3Prothrombin3.4.21.50.441
1ddsMTXDihydrofolate reductase1.5.1.30.441
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.441
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.441
1ivrCBAAspartate aminotransferase, mitochondrial2.6.1.10.441
1p4mADPRiboflavin kinase2.7.1.260.441
1pr4MTPPurine nucleoside phosphorylase DeoD-type/0.441
1ypeUIPProthrombin3.4.21.50.441
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.441
2oo7AP5Adenylate kinase/0.441
2owuSAHDiphthine synthase/0.441
2rtoIMIStreptavidin/0.441
3b9oFMNAlkane monoxygenase/0.441
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4cf7ADPAdenylate kinase/0.441
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.441
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4gxs0YSGlutamate receptor 2/0.441
4m6kFOLDihydrofolate reductase1.5.1.30.441
4n8iCOAPutative 4-hydroxybutyrate coenzyme A transferase/0.441
4oe4NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.441
4pahLNRPhenylalanine-4-hydroxylase1.14.16.10.441
4utkFNRXenobiotic reductase/0.441
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.441
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
5cp8TCUEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
5ebuFMNLactate oxidase/0.441
7catNDPCatalase1.11.1.60.441
3emlZMAAdenosine receptor A2a/0.441
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1l7x700Glycogen phosphorylase, liver form2.4.1.10.440
1qorNDPQuinone oxidoreductase 1/0.440
1rc4DDFDihydrofolate reductase1.5.1.30.440
1tilATPAnti-sigma F factor/0.440
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.440
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.440
2bdyUNBProthrombin3.4.21.50.440
2bf4FADNADPH--cytochrome P450 reductase/0.440
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.440
2e8qSAHDiphthine synthase/0.440
2gesCOKPantothenate kinase2.7.1.330.440
2gouFMNNADH:flavin oxidoreductase Sye1/0.440
2jh0701Prothrombin3.4.21.50.440
2v58LZJBiotin carboxylase6.3.4.140.440
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.440
3dlaNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.440
3fe1ADPHeat shock 70 kDa protein 6/0.440
3jziJZLBiotin carboxylase6.3.4.140.440
3nksACJProtoporphyrinogen oxidase1.3.3.40.440
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.440
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.440
4arbC57Acetylcholinesterase3.1.1.70.440
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.440
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.440
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.440
4ej1FOLDihydrofolate reductase1.5.1.30.440
4iah1DXAlr2278 protein/0.440
4kotCE3Uncharacterized protein/0.440
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.440
4qaiFMNNADPH dehydrogenase/0.440
4uohADPNucleoside diphosphate kinase/0.440
5burATP2-succinylbenzoate--CoA ligase/0.440