sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2fke | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2fke | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 1.000 | |
| 1fkd | 818 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.814 | |
| 4dz2 | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.662 | |
| 1fkj | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.660 | |
| 1a7x | FKA | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.646 | |
| 1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.643 | |
| 1fki | SB1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.637 | |
| 1j4h | SUB | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.635 | |
| 4dh0 | MR8 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.633 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.631 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.631 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.631 | |
| 1bkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.630 | |
| 1fkl | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.629 | |
| 3o5r | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.627 | |
| 1c9h | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1B | 5.2.1.8 | 0.626 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.626 | |
| 2dg3 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.624 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.622 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.622 | |
| 2dg9 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.618 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.608 | |
| 4qt3 | RAP | Peptidylprolyl isomerase | / | 0.600 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.598 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.598 | |
| 1q6i | FK5 | FKBP-type peptidyl-prolyl cis-trans isomerase FkpA | 5.2.1.8 | 0.596 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.595 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.595 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.595 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.593 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.589 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.587 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.587 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.583 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.583 | |
| 4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.578 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.572 | |
| 1fkh | SBX | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.571 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.570 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.569 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.569 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.565 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.560 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.560 | |
| 4drp | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.560 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.559 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.548 | |
| 1fkg | SB3 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.535 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.524 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.523 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.516 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.511 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.509 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.505 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.504 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.503 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.503 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.503 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.502 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.500 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.500 | |
| 3iu8 | T03 | Methionine aminopeptidase 2 | / | 0.499 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.499 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.498 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.498 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.497 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.497 | |
| 1oz0 | MS1 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.496 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.496 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.496 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.496 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.495 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.495 | |
| 2p99 | YE6 | Methionine aminopeptidase | / | 0.494 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.494 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.493 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.491 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.490 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.489 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.489 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.489 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.488 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.486 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.486 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.486 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.485 | |
| 3pkc | Y08 | Methionine aminopeptidase 2 | / | 0.485 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.485 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.484 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.484 | |
| 4flj | Y08 | Methionine aminopeptidase 1 | / | 0.484 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.484 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.483 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.483 | |
| 1c7o | PPG | Hemolysin | / | 0.482 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.482 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.482 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.482 | |
| 2r8p | T6F | Transketolase 1 | / | 0.482 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.482 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.481 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.481 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.481 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.481 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.481 | |
| 4kq1 | U5P | Glycogen [starch] synthase | / | 0.481 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.480 | |
| 2p98 | YE7 | Methionine aminopeptidase | / | 0.480 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.480 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.480 | |
| 2dxf | GNP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.479 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 3g5i | DNB | Pyrimidine-specific ribonucleoside hydrolase RihA | / | 0.479 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.478 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.478 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.477 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.477 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.476 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.476 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.476 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 1el4 | CTZ | Obelin | / | 0.475 | |
| 1uhh | CZP | Aequorin-2 | / | 0.475 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.475 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.475 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.475 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.474 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.474 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.474 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.474 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.474 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.474 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.474 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.474 | |
| 1vhz | APR | ADP compounds hydrolase NudE | 3.6.1 | 0.473 | |
| 3i0o | SMI | Spectinomycin phosphotransferase | / | 0.473 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.473 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.473 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.473 | |
| 4hn1 | TYD | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.473 | |
| 3ei8 | PL5 | LL-diaminopimelate aminotransferase, chloroplastic | / | 0.472 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.472 | |
| 4n1g | CEI | Obelin | / | 0.472 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.471 | |
| 2evm | FC2 | Methionine aminopeptidase | / | 0.471 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.471 | |
| 4d2d | ALA_ALA_ALA | Di-or tripeptide:H+ symporter | / | 0.471 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.471 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.470 | |
| 1lbm | 137 | N-(5'-phosphoribosyl)anthranilate isomerase | 5.3.1.24 | 0.470 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 3b4p | 3B4 | Phenazine biosynthesis protein A/B | / | 0.470 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.470 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.470 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.470 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.470 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.470 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.469 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.469 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.469 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.469 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.469 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.469 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.469 | |
| 1m9n | AMZ | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.468 | |
| 2gg9 | U16 | Methionine aminopeptidase | / | 0.468 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.468 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.468 | |
| 4xp4 | COC | Sodium-dependent dopamine transporter | / | 0.468 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.467 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.467 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.467 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.467 | |
| 3d27 | W29 | Methionine aminopeptidase | / | 0.467 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.467 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.466 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.466 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.466 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.466 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.466 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.466 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.465 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.465 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.465 | |
| 3l7g | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.465 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.465 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.465 | |
| 5dv2 | C5P | CCR4-NOT transcription complex subunit 6-like | 3.1.13.4 | 0.465 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.464 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.464 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.464 | |
| 4iks | TFD | Methionine aminopeptidase 1 | / | 0.464 | |
| 4ikz | AFS | Di-tripeptide ABC transporter (Permease) | / | 0.464 | |
| 1i9c | 5AD | Glutamate mutase epsilon subunit | / | 0.463 | |
| 1xuz | MMN | Capsule biosynthesis protein | / | 0.463 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.463 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.463 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.463 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.463 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.463 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.463 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.463 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.463 | |
| 3qvi | K95 | HAP protein | / | 0.463 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.463 | |
| 4nqg | CZH | Mitrocomin | / | 0.463 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.463 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.463 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.463 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.462 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.462 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.462 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.462 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.462 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.462 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.461 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.461 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.461 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.460 | |
| 2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.460 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.460 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.460 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.460 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.460 | |
| 5c8d | 5AD | Probable transcriptional regulator | / | 0.460 | |
| 1by5 | GLY_GLY_GLY_AHO_AHO_AHO_FE | Ferrichrome-iron receptor | / | 0.459 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.459 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.459 | |
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.459 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.459 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.459 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.459 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.459 | |
| 3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.459 | |
| 3zgz | 84T | Leucine--tRNA ligase | / | 0.459 | |
| 5d4v | YGP | Uncharacterized protein MJ0489 | / | 0.459 | |
| 5i2f | BS5 | Histidine triad nucleotide-binding protein 1 | 3 | 0.459 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.459 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.458 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.458 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.458 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.458 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.458 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.458 | |
| 4hxx | 1AY | Methionine aminopeptidase 1 | / | 0.458 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.458 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.457 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.457 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.457 | |
| 2gg2 | U12 | Methionine aminopeptidase | / | 0.457 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.457 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.457 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.457 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.457 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 3dr7 | GPD | GDP-perosamine synthase | / | 0.457 | |
| 4fll | YZ6 | Methionine aminopeptidase 1 | / | 0.457 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.457 | |
| 5c3r | HMU | Thymine dioxygenase | / | 0.457 | |
| 5fmm | MGT | Polymerase basic protein 2 | / | 0.457 | |
| 1dmw | HBI | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.456 | |
| 1lke | DOG | Bilin-binding protein | / | 0.456 | |
| 1tg2 | H2B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.456 | |
| 2a5c | 8DA | Avidin | / | 0.456 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.456 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.456 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 4a1o | AMZ | Bifunctional purine biosynthesis protein PurH | 2.1.2.3 | 0.456 | |
| 4kl1 | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.456 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.456 | |
| 4x81 | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.456 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.456 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.456 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.455 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.455 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.455 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.455 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.455 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.455 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.455 | |
| 4e2y | JHZ | Methyltransferase | / | 0.455 | |
| 4flk | Y10 | Methionine aminopeptidase 1 | / | 0.455 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.455 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.455 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.455 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.454 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.454 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.454 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.454 | |
| 2g6p | HM2 | Methionine aminopeptidase 1 | / | 0.454 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.454 | |
| 2q93 | B21 | Methionine aminopeptidase | / | 0.454 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.454 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.454 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.454 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4cb4 | MGT | Polymerase basic protein 2 | / | 0.454 | |
| 4e31 | JHZ | Methyltransferase | / | 0.454 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.454 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 1vfs | DCS | Alanine racemase | / | 0.453 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 2b0q | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.453 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.453 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.453 | |
| 2v5u | FMN | Flavodoxin | / | 0.453 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.453 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.453 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.453 | |
| 4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.453 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.453 | |
| 4ikt | TFV | Methionine aminopeptidase 1 | / | 0.453 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.453 | |
| 5fli | QUE | Quercetinase QueD | / | 0.453 | |
| 1pr0 | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.452 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.452 | |
| 1xnz | FCD | Methionine aminopeptidase | / | 0.452 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.452 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.452 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.452 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3vjl | W94 | Dipeptidyl peptidase 4 | / | 0.452 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.452 | |
| 4olf | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.452 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.451 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.451 | |
| 1wkg | POI | [LysW]-aminoadipate semialdehyde transaminase | / | 0.451 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.451 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.451 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.451 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.451 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.451 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.450 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 2npf | MOU | Elongation factor 2 | / | 0.450 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.450 | |
| 2x3j | ATP | AcsD | / | 0.450 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.450 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.450 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.450 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.450 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.450 | |
| 4rel | KMP | Glycosyltransferase | / | 0.450 | |
| 1jf0 | CZH | Obelin | / | 0.449 | |
| 1p4r | 354 | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.449 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.449 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.449 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.449 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.449 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.449 | |
| 2po3 | T4K | 4-dehydrase | / | 0.449 | |
| 2yim | MC4 | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.449 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.449 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.449 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.449 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.449 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.449 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4h0x | NAD | Iota toxin component Ia | / | 0.449 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.449 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.449 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.448 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.448 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.448 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1swg | BTN | Streptavidin | / | 0.448 | |
| 1vyq | DUX | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.448 | |
| 2b1i | 93A | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.448 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.448 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.448 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.448 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.448 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.448 | |
| 3zm6 | 2GN | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.448 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.448 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.448 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.448 | |
| 4img | NGF | N-acetylneuraminate lyase | / | 0.448 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.448 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.447 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.447 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.447 | |
| 2ggb | U17 | Methionine aminopeptidase | / | 0.447 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.447 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 2wvm | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.447 | |
| 3eku | CY9 | Actin-5C | / | 0.447 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.447 | |
| 3ie3 | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.447 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.447 | |
| 1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.446 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.446 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.446 | |
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.446 | |
| 2fbw | CBE | Succinate dehydrogenase cytochrome b, large subunit | / | 0.446 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.446 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3c1o | NAP | Eugenol synthase | / | 0.446 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
| 3h59 | H59 | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.446 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4xcz | T3Q | Qdtf | / | 0.446 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.446 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 5flj | QUE | Quercetinase QueD | / | 0.446 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.445 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.445 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.445 | |
| 1xr2 | C2F | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | 2.1.1.14 | 0.445 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.445 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.445 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.445 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.445 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.445 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.445 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.445 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.445 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.444 | |
| 1aqv | 0HG | Glutathione S-transferase P | 2.5.1.18 | 0.444 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.444 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.444 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.444 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.444 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.444 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.444 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.444 | |
| 2xlu | NA7 | Putative flavin-containing monooxygenase | / | 0.444 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.444 | |
| 3dr4 | G4M | GDP-perosamine synthase | / | 0.444 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.444 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.444 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.444 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.444 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 1acj | THA | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.443 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.443 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.443 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.443 | |
| 2isc | 223 | Purine nucleoside phosphorylase, putative | / | 0.443 | |
| 2plm | SIB | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | 3.5.4.28 | 0.443 | |
| 2xwe | AMF | Glucosylceramidase | 3.2.1.45 | 0.443 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.443 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.443 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3kmy | D8Y | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.443 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.443 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.443 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.443 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.443 | |
| 1eir | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.442 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1jf2 | CZH | Obelin | / | 0.442 | |
| 1pf7 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.442 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.442 | |
| 2gmu | PDG | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.442 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.442 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.442 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.442 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3cow | 52H | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 3e6e | DCS | Alanine racemase | / | 0.442 | |
| 3fx6 | BPX | Carboxypeptidase A1 | 3.4.17.1 | 0.442 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.442 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.442 | |
| 4eyf | PNK | Metallo-beta-lactamase type 2 | / | 0.442 | |
| 4hcy | 0YN | Transketolase | / | 0.442 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4nwi | CTN | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.442 | |
| 4o30 | SAH | Probable Histone-lysine N-methyltransferase ATXR5 | 2.1.1.43 | 0.442 | |
| 4qer | STL | Phospholipase A2 VRV-PL-VIIIa | / | 0.442 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.442 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.441 | |
| 1j8u | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.441 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.441 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.441 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.441 | |
| 1vf3 | GDN | Glutathione S-transferase 3 | 2.5.1.18 | 0.441 | |
| 1wkh | PPE | [LysW]-aminoadipate semialdehyde transaminase | / | 0.441 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.441 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.441 | |
| 2c92 | TP6 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.441 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.441 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.441 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.441 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4to5 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.441 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.440 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1e2n | RCA | Thymidine kinase | / | 0.440 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.440 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.440 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.440 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.440 | |
| 3i97 | 8DR | Neuropilin-1 | / | 0.440 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.440 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.440 | |
| 3sfx | JAN | Uncharacterized protein | / | 0.440 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.440 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.440 | |
| 4ikr | PVP | Methionine aminopeptidase 1 | / | 0.440 | |
| 4lng | JAN | CaaX farnesyltransferase beta subunit Ram1 | / | 0.440 |