sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 1.000 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.594 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.544 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.532 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.525 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.525 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.518 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.516 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.514 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.505 | |
| 3th5 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.501 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.498 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.492 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.492 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.489 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.487 | |
| 2qme | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.486 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.485 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.482 | |
| 2rge | GNP | GTPase HRas | / | 0.479 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.478 | |
| 3sbd | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.474 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.471 | |
| 3eg5 | GNP | Cell division control protein 42 homolog | / | 0.470 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.467 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.467 | |
| 4dvg | GSP | Rho family GTPase | / | 0.466 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.464 | |
| 4xvr | GNP | GTPase HRas | / | 0.464 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.462 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.462 | |
| 3v4f | GNP | GTPase HRas | / | 0.462 | |
| 4nyi | GNP | GTPase HRas | / | 0.462 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.460 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.459 | |
| 1z2c | GNP | Rho-related GTP-binding protein RhoC | / | 0.459 | |
| 2c5l | GTP | GTPase HRas | / | 0.456 | |
| 3ddc | GNP | GTPase HRas | / | 0.456 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.453 | |
| 3tgp | GNP | GTPase HRas | / | 0.453 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.453 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.452 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.452 | |
| 1e96 | GTP | Ras-related C3 botulinum toxin substrate 1 | / | 0.451 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.451 | |
| 4dsn | GCP | GTPase KRas | / | 0.450 | |
| 4mit | GTP | Rho-related protein racC | / | 0.450 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.450 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.449 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.449 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.446 | |
| 1ibr | GNP | GTP-binding nuclear protein Ran | / | 0.445 | |
| 3lbn | GNP | GTPase HRas | / | 0.445 | |
| 3oiv | GNP | GTPase HRas | / | 0.444 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.444 | |
| 4nyj | GNP | GTPase HRas | / | 0.441 |