sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ffq | GSP | Ras-related protein Rab-6B |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2ffq | GSP | Ras-related protein Rab-6B | / | 1.000 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.610 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.566 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.563 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.558 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.556 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.546 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.545 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.537 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.533 | |
| 3law | GNP | Ras-related protein Rab-7a | / | 0.529 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.520 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.517 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.515 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.512 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.509 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.504 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.499 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.498 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.494 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.494 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.487 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.481 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.481 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.480 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.479 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.475 | |
| 3tnf | GNP | Ras-related protein Rab-8A | / | 0.475 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.474 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.472 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.471 | |
| 3tkl | GTP | Ras-related protein Rab-1A | / | 0.471 | |
| 3lbn | GNP | GTPase HRas | / | 0.465 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.459 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.457 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.457 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.456 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.455 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.454 | |
| 1n6l | GTP | Ras-related protein Rab-5A | / | 0.453 | |
| 4kvg | GTP | Ras-related protein Rap-1A | / | 0.453 | |
| 4k81 | GTP | GTPase HRas | / | 0.451 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.443 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.442 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.441 | |
| 2bku | GTP | GTP-binding nuclear protein Ran | / | 0.440 | |
| 3ddc | GNP | GTPase HRas | / | 0.440 |