sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2fav | APR | Nonstructural polyprotein pp1a |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2fav | APR | Nonstructural polyprotein pp1a | / | 1.000 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.489 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.470 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.460 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.458 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.456 | |
| 3gqo | APR | Non-structural polyprotein | / | 0.455 | |
| 3sii | A1R | Uncharacterized protein | / | 0.454 | |
| 5cb5 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.452 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.448 | |
| 5dp2 | NAP | CurF | / | 0.444 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.443 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.443 | |
| 4p63 | NAD | Probable deoxyhypusine synthase | 2.5.1.46 | 0.443 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.442 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 3sig | AR6 | Uncharacterized protein | / | 0.441 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.440 |