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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.667
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.609
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.607
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.598
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.596
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.572
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.560
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.557
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.525
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.508
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.504
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.489
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
1fm4DXCMajor pollen allergen Bet v 1-L/0.448
3x2wATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
1xe55FEPlasmepsin-23.4.23.390.444
4a83DXCMajor pollen allergen Bet v 1-A/0.443
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440