sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2f6r | ACO | Bifunctional coenzyme A synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2f6r | ACO | Bifunctional coenzyme A synthase | / | 1.000 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.487 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.481 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.480 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.464 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.462 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.461 | |
| 2qs4 | LY5 | Glutamate receptor ionotropic, kainate 1 | / | 0.457 | |
| 3ogw | IMN | Lactoperoxidase | 1.11.1.7 | 0.457 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.456 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.454 | |
| 1osv | CHC | Bile acid receptor | / | 0.453 | |
| 2q66 | ATP | Poly(A) polymerase | 2.7.7.19 | 0.453 | |
| 1g41 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.451 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.450 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.448 | |
| 2qs1 | UB1 | Glutamate receptor ionotropic, kainate 1 | / | 0.447 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.447 | |
| 2cmo | M1L | Glutamate receptor 2 | / | 0.446 | |
| 3s2v | 3HU | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.445 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.443 | |
| 1owo | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.440 |