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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ewpTXFEstrogen-related receptor gamma

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2ewpTXFEstrogen-related receptor gamma/1.000
2gpuOHTEstrogen-related receptor gamma/0.567
2p7zOHTEstrogen-related receptor gamma/0.552
1yinCM3Estrogen receptor/0.487
1s9qOHTEstrogen-related receptor gamma/0.477
1sj0E4DEstrogen receptor/0.474
2gpvOHTEstrogen-related receptor gamma/0.466
1ndeMONEstrogen receptor beta/0.460
4othDRNSerine/threonine-protein kinase N1/0.457
1uomPTIEstrogen receptor/0.453
1xqcAEJEstrogen receptor/0.447
1xp6AIUEstrogen receptor/0.446
3gc8B45Mitogen-activated protein kinase 112.7.11.240.444
2gd0MRSProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.441
2qe4JJ3Estrogen receptor/0.440