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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2emuSAHDiphthine synthase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2emuSAHDiphthine synthase/1.000
2emrSAHDiphthine synthase/0.854
2eh5SAHDiphthine synthase/0.849
2dsgSAHDiphthine synthase/0.840
2eniSAHDiphthine synthase/0.823
2ehlSAHDiphthine synthase/0.821
2dxvSAHDiphthine synthase/0.814
2e8sSAHDiphthine synthase/0.813
2p6dSAHDiphthine synthase/0.810
2pb4SAHDiphthine synthase/0.810
2dxwSAHDiphthine synthase/0.805
2pcmSAHDiphthine synthase/0.802
2pb6SAHDiphthine synthase/0.796
2ejkSAHDiphthine synthase/0.792
2dv7SAHDiphthine synthase/0.787
2owkSAHDiphthine synthase/0.780
2e8qSAHDiphthine synthase/0.772
2ek7SAHDiphthine synthase/0.759
2eh2SAHDiphthine synthase/0.756
2dv4SAHDiphthine synthase/0.755
2eglSAHDiphthine synthase/0.751
2ek2SAHDiphthine synthase/0.739
2huxSAHDiphthine synthase/0.738
2e16SAHDiphthine synthase/0.736
2en5SAHDiphthine synthase/0.734
2ekaSAHDiphthine synthase/0.733
2p6kSAHDiphthine synthase/0.730
2e8rSAHDiphthine synthase/0.720
2e8hSAHDiphthine synthase/0.719
2eleSAHDiphthine synthase/0.719
2hutSAHDiphthine synthase/0.716
2e17SAHDiphthine synthase/0.704
2e7rSAHDiphthine synthase/0.698
2ed5SAHDiphthine synthase/0.696
2e4nSAHDiphthine synthase/0.694
2el0SAHDiphthine synthase/0.693
2egsSAHDiphthine synthase/0.691
2pcgSAHDiphthine synthase/0.689
1wngSAHDiphthine synthase/0.687
2eldSAHDiphthine synthase/0.683
2p5cSAHDiphthine synthase/0.680
2e15SAHDiphthine synthase/0.679
2p6lSAHDiphthine synthase/0.679
2p2xSAHDiphthine synthase/0.671
2p5fSAHDiphthine synthase/0.670
1vceSAHDiphthine synthase/0.669
2dsiSAHDiphthine synthase/0.669
2ek4SAHDiphthine synthase/0.669
2dekSAHDiphthine synthase/0.668
2ek3SAHDiphthine synthase/0.666
2pckSAHDiphthine synthase/0.665
2dv3SAHDiphthine synthase/0.663
2eeqSAHDiphthine synthase/0.659
2egbSAHDiphthine synthase/0.654
2owvSAHDiphthine synthase/0.654
2pciSAHDiphthine synthase/0.653
2pchSAHDiphthine synthase/0.651
2p6iSAHDiphthine synthase/0.650
2pb5SAHDiphthine synthase/0.649
2dxxSAHDiphthine synthase/0.648
2dv5SAHDiphthine synthase/0.647
2el3SAHDiphthine synthase/0.647
2hr8SAHDiphthine synthase/0.646
2z6rSAHDiphthine synthase/0.642
2huvSAHDiphthine synthase/0.638
2e08SAHDiphthine synthase/0.622
2owuSAHDiphthine synthase/0.610
2ejzSAHDiphthine synthase/0.609
2owgSAHDiphthine synthase/0.609
2e07SAHDiphthine synthase/0.600
2ejjSAHDiphthine synthase/0.599
2eh4SAHDiphthine synthase/0.593
2owfSAHDiphthine synthase/0.592
2p9dSAHDiphthine synthase/0.590
2pcaSAHDiphthine synthase/0.586
2huqSAHDiphthine synthase/0.551
2dshSAHDiphthine synthase/0.537
2ed3SAHDiphthine synthase/0.527
3gw9VNILanosterol 14-alpha-demethylase/0.526
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.505
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.504
1xe55FEPlasmepsin-23.4.23.390.503
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.501
4g7gVFVLanosterol 14-alpha-demethylase/0.500
1dirNADDihydropteridine reductase1.5.1.340.495
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.495
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.495
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.494
3up5FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.494
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.492
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.485
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.485
2y3sTIRTamL/0.484
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.483
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.483
1t2cNAIL-lactate dehydrogenase1.1.1.270.482
1g63FMNEpidermin decarboxylase4.1.10.481
1tj0FADBifunctional protein PutA1.5.5.20.481
1x1cSAHC-20 methyltransferase/0.481
2ifaFMNUncharacterized protein/0.481
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.481
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.481
1lbcCYZGlutamate receptor 2/0.480
3ig6438Urokinase-type plasminogen activator3.4.21.730.480
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.479
3c1y2BADNA integrity scanning protein DisA/0.479
4bfzZVZPantothenate kinase2.7.1.330.479
1x1aSAMC-20 methyltransferase/0.478
2gjlFMNNitronate monooxygenase1.13.12.160.478
2qbuSAHPrecorrin-2 methyltransferase/0.478
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.478
1g1aNADdTDP-glucose 4,6-dehydratase/0.477
1xe65FPPlasmepsin-23.4.23.390.477
2x06NADL-sulfolactate dehydrogenase/0.477
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.477
2wedPP6Penicillopepsin-13.4.23.200.476
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.476
4g3jVNTLanosterol 14-alpha-demethylase/0.476
1kkq471Peroxisome proliferator-activated receptor alpha/0.475
1nzdUPGDNA beta-glucosyltransferase/0.475
1w6hTITPlasmepsin-23.4.23.390.475
2a94AP0L-lactate dehydrogenase1.1.1.270.475
1bxoPP7Penicillopepsin-13.4.23.200.474
3a3gDLZLumazine protein/0.474
3ijoB4DGlutamate receptor 2/0.474
2q5g1FAPeroxisome proliferator-activated receptor delta/0.473
1h8hATPATP synthase subunit alpha, mitochondrial/0.472
1h8hATPATP synthase subunit beta, mitochondrial3.6.3.140.472
2b53D23Cyclin-dependent kinase 22.7.11.220.472
3lqfNADGalactitol dehydrogenase/0.472
4dbzNDPPutative ketoacyl reductase1.3.10.472
2q7vFADThioredoxin reductase/0.471
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.471
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.471
1bxqPP8Penicillopepsin-13.4.23.200.470
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.470
4ejmNAPPutative zinc-binding dehydrogenase/0.470
1dhrNADDihydropteridine reductase1.5.1.340.469
1j1zATPArgininosuccinate synthase/0.469
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.469
1x1dSAHC-20 methyltransferase/0.469
2dftADPShikimate kinase2.7.1.710.469
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
3wv9FEGHmd co-occurring protein HcgE/0.469
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.469
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.469
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.468
2wecPP5Penicillopepsin-13.4.23.200.468
3slkNDPPolyketide synthase extender module 2/0.468
3zh8C58Protein kinase C iota type2.7.11.130.468
1xddAAYIntegrin alpha-L/0.467
1xs7MMIBeta-secretase 13.4.23.460.467
2gnaGDUUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.467
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.467
2q4bNAPUncharacterized protein At5g02240/0.467
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.467
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.467
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
4h3f10OBeta-secretase 13.4.23.460.467
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.466
2pswCOAN-alpha-acetyltransferase 50/0.466
2w06FRVCyclin-dependent kinase 22.7.11.220.466
2xhd7T9Glutamate receptor 2/0.466
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
1jedADPSulfate adenylyltransferase/0.465
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.465
2zvcSAHPrecorrin-3 C17-methyltransferase/0.465
3lpjZ75Beta-secretase 13.4.23.460.465
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.465
1tqf32PBeta-secretase 13.4.23.460.464
2ebaFADPutative glutaryl-CoA dehydrogenase/0.464
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.464
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.464
2rlcCHDCholoylglycine hydrolase3.5.1.240.464
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3q43D66M1 family aminopeptidase3.4.110.464
4wriOKAOkadaic acid binding protein 2-alpha/0.464
1kp3ATPArgininosuccinate synthase6.3.4.50.463
2oapANPType II secretion system protein (GspE-2)/0.463
3orfNADDihydropteridine reductase1.5.1.340.463
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.463
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.463
4bfxZVXPantothenate kinase2.7.1.330.463
4djy0KRBeta-secretase 13.4.23.460.463
4dpy2P0Mevalonate diphosphate decarboxylase/0.463
4du82P0Mevalonate diphosphate decarboxylase/0.463
4q71FADBifunctional protein PutA/0.463
4wudANPDNA gyrase subunit B/0.463
1ma0NADAlcohol dehydrogenase class-31.1.1.10.462
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.462
2irzI02Beta-secretase 13.4.23.460.462
4egbNADdTDP-glucose 4,6-dehydratase/0.462
4i8zG08Gag-Pol polyprotein3.4.23.160.462
4m83ERYOleandomycin glycosyltransferase2.4.10.462
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.462
1ep1FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.461
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.461
1y4lSVRBasic phospholipase A2 homolog 2/0.461
2y4gTIRTamL/0.461
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.461
3u9eCOALmo1369 protein/0.461
4ji91M3Tyrosine-protein kinase JAK2/0.461
5dp2NAPCurF/0.461
2g1s4IGRenin3.4.23.150.460
2givACOHistone acetyltransferase KAT8/0.460
2is0I03Beta-secretase 13.4.23.460.460
2p83MR0Beta-secretase 13.4.23.460.460
3d91REMRenin3.4.23.150.460
3uoyFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.460
3vx4ATPPutative ABC transporter, ATP-binding protein ComA/0.460
4h3j10WBeta-secretase 13.4.23.460.460
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.460
1f8fNADBenzyl alcohol dehydrogenase/0.459
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1tehNADAlcohol dehydrogenase class-31.1.1.10.459
1vikBAYGag-Pol polyprotein/0.459
2ahrNAPPyrroline-5-carboxylate reductase/0.459
2bjfDXCCholoylglycine hydrolase3.5.1.240.459
3ik6HCZGlutamate receptor 2/0.459
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.459
3v0p4GWHisto-blood group ABO system transferase/0.459
4b65FADL-ornithine N(5)-monooxygenase/0.459
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.459
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.459
5irnADPNucleotide binding oligomerization domain containing 2/0.459
1bmfANPATP synthase subunit alpha, mitochondrial/0.458
1bmfANPATP synthase subunit beta, mitochondrial3.6.3.140.458
1geeNADGlucose 1-dehydrogenase1.1.1.470.458
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.458
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.458
2p5uNADUDP-glucose 4-epimerase/0.458
2v7qATPATP synthase subunit alpha, mitochondrial/0.458
2v7qATPATP synthase subunit beta, mitochondrial3.6.3.140.458
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3p62FMNPentaerythritol tetranitrate reductase/0.458
4f5yC2EStimulator of interferon genes protein/0.458
4iv6FDAIsovaleryl-CoA dehydrogenase/0.458
4prvADPDNA gyrase subunit B/0.458
4yxm2BADNA integrity scanning protein DisA/0.458
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.458
5hwsNAP2-dehydropantoate 2-reductase/0.458
1e1qANPATP synthase subunit alpha, mitochondrial/0.457
1e1qANPATP synthase subunit beta, mitochondrial3.6.3.140.457
1xl5190Gag-Pol polyprotein3.4.23.160.457
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.457
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.457
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.457
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3nutSAHPrecorrin-3 methylase/0.457
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.457
3vt7VDXVitamin D3 receptor/0.457
4b63FADL-ornithine N(5)-monooxygenase/0.457
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.457
4i1iNADMalate dehydrogenase/0.457
4nbwNADShort-chain dehydrogenase/reductase SDR/0.457
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.457
1fm4DXCMajor pollen allergen Bet v 1-L/0.456
1msmJE2Gag-Pol polyprotein3.4.23.160.456
1o0sNAINAD-dependent malic enzyme, mitochondrial1.1.1.380.456
1udaUFGUDP-glucose 4-epimerase5.1.3.20.456
2c20NADUDP-glucose 4-epimerase/0.456
2fznFADBifunctional protein PutA1.5.5.20.456
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.456
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3c212BADNA integrity scanning protein DisA/0.456
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.456
3ixj586Beta-secretase 13.4.23.460.456
4dc0NDPPutative ketoacyl reductase1.3.10.456
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.456
4irnFADAnaB/0.456
4q0kGA3Phytohormone-binding protein/0.456
4y3jHICEndothiapepsin3.4.23.220.456
1f8wFADNADH peroxidase1.11.1.10.455
2gv8NDPThiol-specific monooxygenase1.14.130.455
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.455
2rcyNAPPyrroline-5-carboxylate reductase/0.455
3jziJZLBiotin carboxylase6.3.4.140.455
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
4rquNADAlcohol dehydrogenase class-P/0.455
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.455
1me6IVSPlasmepsin-23.4.23.390.454
1ptjNAPNAD(P) transhydrogenase subunit beta1.6.1.20.454
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.454
2ilvC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.454
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.454
2zvbSAHPrecorrin-3 C17-methyltransferase/0.454
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.454
3oeeANPATP synthase subunit alpha, mitochondrial/0.454
3oeeANPATP synthase subunit beta, mitochondrial3.6.3.140.454
3r9uFADThioredoxin reductase/0.454
3vdqNAD3-hydroxybutyrate dehydrogenase/0.454
3vqsJT1Genome polyprotein/0.454
4a8v2ANMajor pollen allergen Bet v 1-J/0.454
4xguADPPutative pachytene checkpoint protein 2/0.454
4yaoFMNNADPH--cytochrome P450 reductase/0.454
1zioAP5Adenylate kinase/0.453
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.453
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.453
3iltTRUGlutamate receptor 2/0.453
3w8eNAD3-hydroxybutyrate dehydrogenase/0.453
4b78KGGBeta-secretase 13.4.23.460.453
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.453
4j0v1H7Beta-secretase 13.4.23.460.453
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.453
5jscFADPutative acyl-CoA dehydrogenase/0.453
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.452
2qs4LY5Glutamate receptor ionotropic, kainate 1/0.452
2y3rTRKTamL/0.452
3b2eADPATPase GET3/0.452
3b6zCO7Enoyl reductase LovC10.452
3enkUPGUDP-glucose 4-epimerase/0.452
3hl0NADMaleylacetate reductase/0.452
3oev3OEProteasome subunit beta type-53.4.25.10.452
3oev3OEProteasome subunit beta type-63.4.25.10.452
3s5wFADL-ornithine N(5)-monooxygenase/0.452
4bb3KKAIsopenicillin N synthase1.21.3.10.452
4dx9SER_ALA_VAL_THRIntegrin beta-1/0.452
4dx9SER_ALA_VAL_THRIntegrin beta-1-binding protein 1/0.452
4m4922YL-lactate dehydrogenase A chain1.1.1.270.452
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.452
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.452
4tuvCPZCytochrome P450 1191.140.452
4xr9NADCalS8/0.452
1b2lNDCAlcohol dehydrogenase1.1.1.10.451
1bwsNDPGDP-L-fucose synthase/0.451
1ep3FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.451
1v9aSAHUncharacterized protein/0.451
2pj4414Carboxypeptidase B/0.451
2ztmNADD(-)-3-hydroxybutyrate dehydrogenase/0.451
3d4pNADL-lactate dehydrogenase 11.1.1.270.451
3d8bADPFidgetin-like protein 13.6.40.451
3i25MV7Beta-secretase 13.4.23.460.451
3phjDHKShikimate dehydrogenase (NADP(+))/0.451
3pqbVGPPutative oxidoreductase/0.451
3to6LYS_CMCHistone acetyltransferase ESA1/0.451
4dh60KNBeta-secretase 13.4.23.460.451
1bil0IURenin3.4.23.150.450
1c6yMK1Protease/0.450
1cf3FADGlucose oxidase1.1.3.40.450
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.450
1korANPArgininosuccinate synthase/0.450
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.450
1x1bSAHC-20 methyltransferase/0.450
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.450
2fonFADAcyl-coenzyme A oxidase/0.450
2ft9CHDFatty acid-binding protein 2, liver/0.450
2g1r3IGRenin3.4.23.150.450
2g247IGRenin3.4.23.150.450
2iko7IGRenin3.4.23.150.450
2iqgF2IBeta-secretase 13.4.23.460.450
2ovhAS0Progesterone receptor/0.450
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
2znnS44Peroxisome proliferator-activated receptor alpha/0.450
3clxX22E3 ubiquitin-protein ligase XIAP6.3.20.450
3em3478Gag-Pol polyprotein3.4.23.160.450
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.450
3nsh957Beta-secretase 13.4.23.460.450
3t7x4SHEndothiapepsin3.4.23.220.450
4fxy0W2Neurolysin, mitochondrial3.4.24.160.450
4i0i957Beta-secretase 13.4.23.460.450
4r21STRCytochrome P450 family 17 polypeptide 2/0.450
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.450
1cdoNADAlcohol dehydrogenase 11.1.1.10.449
1eioGCHGastrotropin/0.449
1gcoNADGlucose 1-dehydrogenase1.1.1.470.449
1ppl1Z7Penicillopepsin-13.4.23.200.449
1qrpHH0Pepsin A-43.4.23.10.449
1zeoC01Peroxisome proliferator-activated receptor gamma/0.449
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.449
2rh9IGPTryptophan synthase alpha chain/0.449
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.449
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3h06VBPGlutamate receptor 2/0.449
3wagTYDGlycosyltransferase/0.449
4emtC2EStimulator of interferon genes protein/0.449
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.449
4yqfGDPSeptin-9/0.449
1dr3TAPDihydrofolate reductase1.5.1.30.448
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.448
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.448
1kp2ATPArgininosuccinate synthase6.3.4.50.448
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.448
1udbUFGUDP-glucose 4-epimerase5.1.3.20.448
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.448
2a92NAIL-lactate dehydrogenase/0.448
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.448
2he5NDPAldo-keto reductase family 1 member C211.1.10.448
2iyfERYOleandomycin glycosyltransferase2.4.10.448
2vwqNAPGlucose 1-dehydrogenase/0.448
2znq401Peroxisome proliferator-activated receptor delta/0.448
3ai3NDPNADPH-sorbose reductase/0.448
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.448
3lpkZ76Beta-secretase 13.4.23.460.448
3toxNAPPutative oxidoreductase/0.448
3ut5LOCTubulin beta chain/0.448
4b64FADL-ornithine N(5)-monooxygenase/0.448
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.448
4ipw1G7Mycocyclosin synthase1.14.21.90.448
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
4djhJDCKappa-type opioid receptor/0.448
1fxsNAPGDP-L-fucose synthase/0.447
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.447
1pd9CO4Dihydrofolate reductase1.5.1.30.447
1t88CAMCamphor 5-monooxygenase1.14.15.10.447
2c29NAPDihydroflavonol 4-reductase/0.447
2il2LIXRenin3.4.23.150.447
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.447
2x0rNADMalate dehydrogenase/0.447
2xx91NFGlutamate receptor 2/0.447
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.447
3lpiZ74Beta-secretase 13.4.23.460.447
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.447
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.447
3r7kFDAProbable acyl CoA dehydrogenase/0.447
3sf6FDAGlutaryl-CoA dehydrogenase/0.447
3wqmB29Diterpene synthase3.1.7.80.447
4b79NADProbable short-chain dehydrogenase/0.447
4ewo996Beta-secretase 13.4.23.460.447
4frkDWDBeta-secretase 13.4.23.460.447
4r20AERCytochrome P450 family 17 polypeptide 2/0.447
1dr2TAPDihydrofolate reductase1.5.1.30.446
1r2jFADFkbI/0.446
1rneC60Renin3.4.23.150.446
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.446
1uzwCDHIsopenicillin N synthase1.21.3.10.446
1y0s331Peroxisome proliferator-activated receptor delta/0.446
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.446
2g8yNADHydroxycarboxylate dehydrogenase B/0.446
2gevCOKPantothenate kinase2.7.1.330.446
2vkeTACTetracycline repressor protein class D/0.446
2zbaZBATrichothecene 3-O-acetyltransferase/0.446
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.446
3ixp834Ecdysone receptor/0.446
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3jv7NADSecondary alcohol dehydrogenase/0.446
3lu1NADUDP-N-acetylglucosamine 4-epimerase/0.446
3m30COMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.446
3m30COMMethyl-coenzyme M reductase I subunit beta2.8.4.10.446
3ruaNADUDP-N-acetylglucosamine 4-epimerase/0.446
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.446
4dpf0LGBeta-secretase 13.4.23.460.446
4u0mATPCyclic GMP-AMP synthase/0.446
5f8eSAHPossible transcriptional regulatory protein/0.446
1orrNADCDP-paratose 2-epimerase/0.445
1vp6CMPCyclic nucleotide-gated potassium channel mll3241/0.445
1yqzCOACoenzyme A disulfide reductase/0.445
2hrbNAPCarbonyl reductase [NADPH] 31.1.1.1840.445
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.445
2yxuATPPyridoxal kinase2.7.1.350.445
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3e8xNAPBH1520 protein/0.445
3in6FMNUncharacterized protein/0.445
3rsv3RSBeta-secretase 13.4.23.460.445
3tyvHI3Genome polyprotein2.7.7.480.445
4dmmNAP3-oxoacyl-[acyl-carrier-protein] reductase/0.445
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.445
4k6fNAPPutative Acetoacetyl-CoA reductase/0.445
4lcjNADC-terminal-binding protein 2/0.445
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
4zp0DXCMultidrug transporter MdfA/0.445
1bim0QBRenin3.4.23.150.444
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
1hncGDNGlutathione S-transferase Mu 22.5.1.180.444
1j21ATPArgininosuccinate synthase/0.444
1phgMYTCamphor 5-monooxygenase1.14.15.10.444
2gz7D3FOrf1a polyprotein/0.444
2hizLIJBeta-secretase 13.4.23.460.444
2ph835ABeta-secretase 13.4.23.460.444
3h86AP5Adenylate kinase/0.444
3hyoADPPyridoxal kinase/0.444
3oqfS51Renin3.4.23.150.444
3qe2FMNNADPH--cytochrome P450 reductase/0.444
3sufSUEPolyprotein/0.444
3wb2YGPUncharacterized protein MJ0488/0.444
3wmxNADNAD dependent epimerase/dehydratase/0.444
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
4fn4NADShort chain dehydrogenase/0.444
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.444
4kbyC2EStimulator of interferon genes protein/0.444
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.444
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.444
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.444
5dbgNADIridoid synthase1.3.1.990.444
1a72PADAlcohol dehydrogenase E chain1.1.1.10.443
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1gvt2ZSEndothiapepsin3.4.23.220.443
1jkx138Phosphoribosylglycinamide formyltransferase/0.443
1mp0NADAlcohol dehydrogenase class-31.1.1.10.443
1pjcNADAlanine dehydrogenase/0.443
1rywEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.443
1zdwFLVPrenyltransferase/0.443
2ag5NAD3-hydroxybutyrate dehydrogenase type 2/0.443
2cftPLPPyridoxal phosphate phosphatase/0.443
2npxNADNADH peroxidase1.11.1.10.443
2webPP4Penicillopepsin-13.4.23.200.443
2xlrFADPutative flavin-containing monooxygenase/0.443
3cid318Beta-secretase 13.4.23.460.443
3dv5BAVBeta-secretase 13.4.23.460.443
3otwCOAPhosphopantetheine adenylyltransferase/0.443
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.443
3s1dZIRCytokinin dehydrogenase 11.5.99.120.443
3veu0GOBeta-secretase 13.4.23.460.443
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.443
4dptAGSMevalonate diphosphate decarboxylase/0.443
4eb5PLPCysteine desulfurase IscS 2/0.443
4ejvLCLTranscriptional regulator TcaR/0.443
4f9gC2EStimulator of interferon genes protein/0.443
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.443
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.443
4wucANPDNA gyrase subunit B/0.443
4xumIMNPeroxisome proliferator-activated receptor gamma/0.443
4yvz3ATDNA integrity scanning protein DisA/0.443
5ao1DG3Deoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.443
1di8DTQCyclin-dependent kinase 22.7.11.220.442
1e81M91Endothiapepsin3.4.23.220.442
1f20FADNitric oxide synthase, brain1.14.13.390.442
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.442
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.442
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.442
1mczRMNBenzoylformate decarboxylase4.1.1.70.442
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.442
1w0kADPATP synthase subunit alpha, mitochondrial/0.442
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.442
1xq6NAPUncharacterized protein At5g02240/0.442
1yrdCAMCamphor 5-monooxygenase1.14.15.10.442
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2e94364Geranylgeranyl pyrophosphate synthase/0.442
2nq8ZIDEnoyl-ACP reductase/0.442
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.442
2xvu9DNSerum albumin/0.442
3b70NAPEnoyl reductase LovC10.442
3i6iNDPPutative leucoanthocyanidin reductase 1/0.442
3qwbNDPProbable quinone oxidoreductase1.6.5.50.442
3u8l09QAcetylcholine-binding protein/0.442
4a5lFADThioredoxin reductase/0.442
4a6nFADTetX family tetracycline inactivation enzyme/0.442
4a83DXCMajor pollen allergen Bet v 1-A/0.442
4b4vL34Bifunctional protein FolD/0.442
4bfvZVVPantothenate kinase2.7.1.330.442
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.442
4fv7E94Mitogen-activated protein kinase 12.7.11.240.442
4ips1G4Mycocyclosin synthase1.14.21.90.442
4l4xNDPAmphI/0.442
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.442
4zohFADPutative oxidoreductase FAD-binding subunit/0.442
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.442
1egeFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.441
1qy5NECEndoplasmin/0.441
2dvlFADAcyl-CoA dehydrogenase/0.441
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.441
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2ikuLIYRenin3.4.23.150.441
2qo9ANPEphrin type-A receptor 32.7.10.10.441
2viyVG3Beta-secretase 13.4.23.460.441
2vnaNAPProstaglandin reductase 21.3.1.480.441
2ylzFADPhenylacetone monooxygenase1.14.13.920.441
3f1kNAPUncharacterized oxidoreductase YciK10.441
3jzdNADMaleylacetate reductase/0.441
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.441
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.441
3t8vBTJM1 family aminopeptidase3.4.110.441
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.441
3v2uATPProtein GAL3/0.441
4a862ANMajor pollen allergen Bet v 1-A/0.441
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.441
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4mv8ACPBiotin carboxylase6.3.4.140.441
5af7FADAcyl-CoA dehydrogenase/0.441
1dg8NDPDihydrofolate reductase1.5.1.30.440
1fy7COAHistone acetyltransferase ESA1/0.440
1h50FMNPentaerythritol tetranitrate reductase/0.440
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.440
1oc1ASVIsopenicillin N synthase1.21.3.10.440
1ppm0P1Penicillopepsin-13.4.23.200.440
1qorNDPQuinone oxidoreductase 1/0.440
2bn4FMNNADPH--cytochrome P450 reductase/0.440
2j83BATUlilysin3.4.240.440
2nniMTKCytochrome P450 2C8/0.440
2vnkFADNADPH:ferredoxin reductase/0.440
2xfiXFIBeta-secretase 13.4.23.460.440
2z54AB1Gag-Pol polyprotein3.4.23.160.440
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.440
3ljtLA3A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.440
3lzs017Gag-Pol polyprotein3.4.23.160.440
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.440
3oibFDAPutative acyl-CoA dehydrogenase/0.440
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.440
3tr05GPGuanylate kinase/0.440
3vyeVYERenin3.4.23.150.440
4dzzADPPlasmid partitioning protein ParF/0.440
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.440
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.440
4h3g10QBeta-secretase 13.4.23.460.440
4ig01FGGag-Pol polyprotein2.7.7.490.440
4j7uNAPSepiapterin reductase1.1.1.1530.440
4qecNAPElxO/0.440