sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2eka | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2eka | SAH | Diphthine synthase | / | 1.000 | |
| 2p6d | SAH | Diphthine synthase | / | 0.851 | |
| 2emr | SAH | Diphthine synthase | / | 0.850 | |
| 2pcm | SAH | Diphthine synthase | / | 0.807 | |
| 2ele | SAH | Diphthine synthase | / | 0.806 | |
| 2eni | SAH | Diphthine synthase | / | 0.798 | |
| 2ehl | SAH | Diphthine synthase | / | 0.797 | |
| 2dxv | SAH | Diphthine synthase | / | 0.793 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.786 | |
| 2dxw | SAH | Diphthine synthase | / | 0.783 | |
| 2e7r | SAH | Diphthine synthase | / | 0.782 | |
| 2pcg | SAH | Diphthine synthase | / | 0.772 | |
| 2ejk | SAH | Diphthine synthase | / | 0.770 | |
| 2p2x | SAH | Diphthine synthase | / | 0.753 | |
| 2egb | SAH | Diphthine synthase | / | 0.752 | |
| 2emu | SAH | Diphthine synthase | / | 0.748 | |
| 2egs | SAH | Diphthine synthase | / | 0.745 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.741 | |
| 2p5c | SAH | Diphthine synthase | / | 0.739 | |
| 2e8s | SAH | Diphthine synthase | / | 0.735 | |
| 2p6k | SAH | Diphthine synthase | / | 0.735 | |
| 2dxx | SAH | Diphthine synthase | / | 0.730 | |
| 2owk | SAH | Diphthine synthase | / | 0.723 | |
| 2p5f | SAH | Diphthine synthase | / | 0.719 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.718 | |
| 2e8r | SAH | Diphthine synthase | / | 0.713 | |
| 2pck | SAH | Diphthine synthase | / | 0.712 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.711 | |
| 2egl | SAH | Diphthine synthase | / | 0.710 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.704 | |
| 2e8q | SAH | Diphthine synthase | / | 0.699 | |
| 2dsg | SAH | Diphthine synthase | / | 0.694 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.693 | |
| 2e08 | SAH | Diphthine synthase | / | 0.687 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.684 | |
| 2hux | SAH | Diphthine synthase | / | 0.683 | |
| 2pch | SAH | Diphthine synthase | / | 0.681 | |
| 2eld | SAH | Diphthine synthase | / | 0.667 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.665 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.663 | |
| 2el0 | SAH | Diphthine synthase | / | 0.663 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.661 | |
| 2e16 | SAH | Diphthine synthase | / | 0.660 | |
| 2en5 | SAH | Diphthine synthase | / | 0.658 | |
| 2p9d | SAH | Diphthine synthase | / | 0.655 | |
| 2p6i | SAH | Diphthine synthase | / | 0.648 | |
| 1vce | SAH | Diphthine synthase | / | 0.647 | |
| 2el3 | SAH | Diphthine synthase | / | 0.647 | |
| 1wng | SAH | Diphthine synthase | / | 0.644 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.644 | |
| 2dsi | SAH | Diphthine synthase | / | 0.640 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.638 | |
| 2hut | SAH | Diphthine synthase | / | 0.638 | |
| 2owg | SAH | Diphthine synthase | / | 0.634 | |
| 2pci | SAH | Diphthine synthase | / | 0.632 | |
| 2pca | SAH | Diphthine synthase | / | 0.630 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.628 | |
| 2owv | SAH | Diphthine synthase | / | 0.626 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.624 | |
| 2e4n | SAH | Diphthine synthase | / | 0.621 | |
| 2huv | SAH | Diphthine synthase | / | 0.616 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.612 | |
| 2e8h | SAH | Diphthine synthase | / | 0.607 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.602 | |
| 2ejj | SAH | Diphthine synthase | / | 0.596 | |
| 2dek | SAH | Diphthine synthase | / | 0.595 | |
| 2dsh | SAH | Diphthine synthase | / | 0.592 | |
| 2p6l | SAH | Diphthine synthase | / | 0.582 | |
| 2e07 | SAH | Diphthine synthase | / | 0.580 | |
| 2eeq | SAH | Diphthine synthase | / | 0.579 | |
| 2e15 | SAH | Diphthine synthase | / | 0.577 | |
| 2e17 | SAH | Diphthine synthase | / | 0.567 | |
| 2huq | SAH | Diphthine synthase | / | 0.565 | |
| 2z6r | SAH | Diphthine synthase | / | 0.565 | |
| 2owu | SAH | Diphthine synthase | / | 0.559 | |
| 2ejz | SAH | Diphthine synthase | / | 0.551 | |
| 2owf | SAH | Diphthine synthase | / | 0.524 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.494 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.491 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.491 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.483 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.482 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.480 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.479 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.479 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.479 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.475 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.472 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.472 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.472 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.471 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.471 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.470 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.470 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.470 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.470 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.469 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.469 | |
| 2y3s | TIR | TamL | / | 0.469 | |
| 1bmf | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.468 | |
| 1bmf | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.468 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.468 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.468 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.467 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.467 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.467 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.466 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.466 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.465 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.465 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.465 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.464 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.464 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.463 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.463 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.462 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.461 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.461 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.459 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.459 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.459 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.459 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.458 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.458 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.458 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.458 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.457 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.457 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.457 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.456 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.456 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.455 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.455 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.455 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.455 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.455 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.454 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.454 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.454 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.454 | |
| 2y4g | TIR | TamL | / | 0.454 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.454 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.454 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.453 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.453 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.453 | |
| 3oev | 3OE | Proteasome subunit beta type-5 | 3.4.25.1 | 0.453 | |
| 3oev | 3OE | Proteasome subunit beta type-6 | 3.4.25.1 | 0.453 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.453 | |
| 5dp2 | NAP | CurF | / | 0.453 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.452 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.452 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.452 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.452 | |
| 3wag | TYD | Glycosyltransferase | / | 0.452 | |
| 4asu | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.452 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.452 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.452 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.451 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.451 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.451 | |
| 3u9e | COA | Lmo1369 protein | / | 0.451 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.451 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.451 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.450 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 2b8v | 3BN | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.450 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.450 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.450 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.450 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.449 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.449 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.449 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.449 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.449 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.449 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.449 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.449 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.449 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.449 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.448 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.448 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.448 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.448 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.448 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.448 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.448 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.448 | |
| 1e79 | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.447 | |
| 1e79 | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.447 | |
| 1h8h | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.447 | |
| 1h8h | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.447 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.447 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.447 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3a3g | DLZ | Lumazine protein | / | 0.447 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.447 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.446 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.446 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.446 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 2d4v | NAD | Isocitrate dehydrogenase [NADP] | / | 0.446 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.446 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.446 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.446 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.446 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.446 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.446 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.446 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.446 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.446 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.445 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.445 | |
| 1gqt | ACP | Ribokinase | / | 0.445 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.445 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.445 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.445 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.445 | |
| 2zju | IM4 | Acetylcholine-binding protein | / | 0.445 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.445 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.445 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.445 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.445 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.444 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.444 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.444 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4k39 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.444 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 1til | ATP | Anti-sigma F factor | / | 0.443 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.443 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.443 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.443 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.443 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.443 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4tm3 | FAD | KtzI | / | 0.443 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.443 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.443 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.443 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.443 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.442 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.442 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.442 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.442 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.442 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.442 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.442 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.442 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.442 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.442 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.442 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.442 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.442 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.442 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.442 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.441 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.441 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.441 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.441 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.441 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.441 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2vce | U2F | UDP-glycosyltransferase 72B1 | / | 0.441 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.441 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.441 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4lut | DCS | Alanine racemase | / | 0.441 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.441 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.441 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.440 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.440 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.440 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.440 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.440 | |
| 3d28 | B34 | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.440 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.440 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.440 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1 | / | 0.440 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1-binding protein 1 | / | 0.440 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.440 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.440 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.440 |