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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2ek4SAHDiphthine synthase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2ek4SAHDiphthine synthase/1.000
2el3SAHDiphthine synthase/0.890
2e4nSAHDiphthine synthase/0.886
2eldSAHDiphthine synthase/0.871
2pb6SAHDiphthine synthase/0.858
2huvSAHDiphthine synthase/0.831
2huxSAHDiphthine synthase/0.810
2pcgSAHDiphthine synthase/0.798
2pchSAHDiphthine synthase/0.789
2e8rSAHDiphthine synthase/0.784
2en5SAHDiphthine synthase/0.772
2e8qSAHDiphthine synthase/0.769
2dv3SAHDiphthine synthase/0.766
2owgSAHDiphthine synthase/0.763
2e7rSAHDiphthine synthase/0.758
2ek2SAHDiphthine synthase/0.748
2pcaSAHDiphthine synthase/0.747
2ek7SAHDiphthine synthase/0.732
2eleSAHDiphthine synthase/0.732
2pb4SAHDiphthine synthase/0.732
2eh4SAHDiphthine synthase/0.731
2huqSAHDiphthine synthase/0.730
2p9dSAHDiphthine synthase/0.721
2pb5SAHDiphthine synthase/0.719
2z6rSAHDiphthine synthase/0.719
2dxxSAHDiphthine synthase/0.718
2e07SAHDiphthine synthase/0.715
2e16SAHDiphthine synthase/0.713
2emuSAHDiphthine synthase/0.713
2dsgSAHDiphthine synthase/0.705
2el0SAHDiphthine synthase/0.700
1wngSAHDiphthine synthase/0.698
2owkSAHDiphthine synthase/0.698
2emrSAHDiphthine synthase/0.697
2ehlSAHDiphthine synthase/0.694
2e8sSAHDiphthine synthase/0.686
1vceSAHDiphthine synthase/0.684
2pckSAHDiphthine synthase/0.682
2eh2SAHDiphthine synthase/0.678
2hutSAHDiphthine synthase/0.675
2eh5SAHDiphthine synthase/0.674
2pcmSAHDiphthine synthase/0.674
2p6dSAHDiphthine synthase/0.673
2dxwSAHDiphthine synthase/0.672
2ed5SAHDiphthine synthase/0.672
2e17SAHDiphthine synthase/0.671
2eniSAHDiphthine synthase/0.667
2dxvSAHDiphthine synthase/0.665
2hr8SAHDiphthine synthase/0.663
2ekaSAHDiphthine synthase/0.659
2p6lSAHDiphthine synthase/0.659
2ejkSAHDiphthine synthase/0.655
2p5cSAHDiphthine synthase/0.651
2dekSAHDiphthine synthase/0.650
2pciSAHDiphthine synthase/0.649
2ek3SAHDiphthine synthase/0.648
2eglSAHDiphthine synthase/0.643
2p6iSAHDiphthine synthase/0.640
2egbSAHDiphthine synthase/0.639
2p5fSAHDiphthine synthase/0.638
2e08SAHDiphthine synthase/0.636
2dv5SAHDiphthine synthase/0.632
2dv4SAHDiphthine synthase/0.631
2ejjSAHDiphthine synthase/0.626
2dv7SAHDiphthine synthase/0.623
2ed3SAHDiphthine synthase/0.618
2owvSAHDiphthine synthase/0.613
2e15SAHDiphthine synthase/0.611
2dsiSAHDiphthine synthase/0.591
2owuSAHDiphthine synthase/0.589
2p2xSAHDiphthine synthase/0.588
2p6kSAHDiphthine synthase/0.588
2e8hSAHDiphthine synthase/0.587
2owfSAHDiphthine synthase/0.587
2ejzSAHDiphthine synthase/0.585
2dshSAHDiphthine synthase/0.584
2egsSAHDiphthine synthase/0.583
2eeqSAHDiphthine synthase/0.566
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.518
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.515
1xe55FEPlasmepsin-23.4.23.390.511
1lbcCYZGlutamate receptor 2/0.510
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.502
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.499
2gjlFMNNitronate monooxygenase1.13.12.160.496
2ifaFMNUncharacterized protein/0.495
2iviACWIsopenicillin N synthase1.21.3.10.493
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.489
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.489
3a3gDLZLumazine protein/0.487
2g1r3IGRenin3.4.23.150.485
2xhd7T9Glutamate receptor 2/0.485
3zkyWT4Isopenicillin N synthase1.21.3.10.485
4i1iNADMalate dehydrogenase/0.485
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.484
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.483
3ijoB4DGlutamate receptor 2/0.482
1bk0ACVIsopenicillin N synthase1.21.3.10.481
2x7hPFNProstaglandin reductase 310.481
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.480
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.480
4ipw1G7Mycocyclosin synthase1.14.21.90.480
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.479
2pswCOAN-alpha-acetyltransferase 50/0.479
3djjFADGlutathione reductase, mitochondrial1.8.1.70.479
4a83DXCMajor pollen allergen Bet v 1-A/0.478
1dirNADDihydropteridine reductase1.5.1.340.477
1h8hATPATP synthase subunit alpha, mitochondrial/0.477
1h8hATPATP synthase subunit beta, mitochondrial3.6.3.140.477
1o97FADElectron transfer flavoprotein subunit alpha/0.477
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.477
4m83ERYOleandomycin glycosyltransferase2.4.10.476
1w6hTITPlasmepsin-23.4.23.390.475
1g63FMNEpidermin decarboxylase4.1.10.474
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.474
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.474
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.474
1dhrNADDihydropteridine reductase1.5.1.340.473
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.473
3sf6FDAGlutaryl-CoA dehydrogenase/0.473
4lxa1YSBeta-secretase 13.4.23.460.473
1mj9COAHistone acetyltransferase ESA1/0.472
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.472
3f3sNADLambda-crystallin homolog/0.472
3ieuGDPGTPase Era/0.472
3wv9FEGHmd co-occurring protein HcgE/0.472
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.471
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
1k7fIAVTryptophan synthase alpha chain/0.470
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.470
4djhJDCKappa-type opioid receptor/0.470
1me6IVSPlasmepsin-23.4.23.390.469
3ig6438Urokinase-type plasminogen activator3.4.21.730.469
4wudANPDNA gyrase subunit B/0.469
1civNAPMalate dehydrogenase [NADP], chloroplastic1.1.1.820.468
1g1aNADdTDP-glucose 4,6-dehydratase/0.468
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.468
3hl0NADMaleylacetate reductase/0.468
3ik6HCZGlutamate receptor 2/0.468
4prvADPDNA gyrase subunit B/0.468
1dr3TAPDihydrofolate reductase1.5.1.30.467
1f8fNADBenzyl alcohol dehydrogenase/0.467
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.467
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.467
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.467
2qimZEAClass 10 plant pathogenesis-related protein/0.467
3ohh3HHBeta-secretase 13.4.23.460.467
1qr6NADNAD-dependent malic enzyme, mitochondrial1.1.1.380.466
2a5kAZPReplicase polyprotein 1ab3.4.220.466
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.466
2gtbAZPOrf1ab polyprotein/0.466
2q4bNAPUncharacterized protein At5g02240/0.466
2vwqNAPGlucose 1-dehydrogenase/0.466
3ru9NADUDP-N-acetylglucosamine 4-epimerase/0.466
4a8v2ANMajor pollen allergen Bet v 1-J/0.466
4bfzZVZPantothenate kinase2.7.1.330.466
1orrNADCDP-paratose 2-epimerase/0.465
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.465
4b4vL34Bifunctional protein FolD/0.465
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.465
1juvNDPDihydrofolate reductase1.5.1.30.464
2bf4FMNNADPH--cytochrome P450 reductase/0.464
2oapANPType II secretion system protein (GspE-2)/0.464
2w3bNDPDihydrofolate reductase1.5.1.30.464
2y0mACOHistone acetyltransferase KAT8/0.464
3bl7DD1m7GpppX diphosphatase3.6.1.590.464
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3gw9VNILanosterol 14-alpha-demethylase/0.464
3kgcLY7Glutamate receptor 2/0.464
4a81DXCMajor pollen allergen Bet v 1-A/0.464
4gsuDWZL,D-transpeptidase 22.3.20.464
1hb1OCVIsopenicillin N synthase1.21.3.10.463
2c20NADUDP-glucose 4-epimerase/0.463
2vkeTACTetracycline repressor protein class D/0.463
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.463
4ejvLCLTranscriptional regulator TcaR/0.463
1xddAAYIntegrin alpha-L/0.462
3ixp834Ecdysone receptor/0.462
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3tjzGNPADP-ribosylation factor 1/0.462
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
4ji91M3Tyrosine-protein kinase JAK2/0.462
4r21STRCytochrome P450 family 17 polypeptide 2/0.462
5dp2NAPCurF/0.462
2iyfERYOleandomycin glycosyltransferase2.4.10.461
3zh8C58Protein kinase C iota type2.7.11.130.461
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.461
1u3dFADCryptochrome-1/0.460
2rlcCHDCholoylglycine hydrolase3.5.1.240.460
2xlrFADPutative flavin-containing monooxygenase/0.460
3phiNDPShikimate dehydrogenase (NADP(+))/0.460
4g3jVNTLanosterol 14-alpha-demethylase/0.460
1t88CAMCamphor 5-monooxygenase1.14.15.10.459
1x1bSAHC-20 methyltransferase/0.459
2il2LIXRenin3.4.23.150.459
2rehFADNitroalkane oxidase1.7.3.10.459
4dzzADPPlasmid partitioning protein ParF/0.459
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.459
4tm4FDAKtzI/0.459
4xr9NADCalS8/0.459
5d3qGDPDynamin-13.6.5.50.459
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.458
1mp0NADAlcohol dehydrogenase class-31.1.1.10.458
1pjcNADAlanine dehydrogenase/0.458
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.458
2qbuSAHPrecorrin-2 methyltransferase/0.458
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.458
2y60M8FIsopenicillin N synthase1.21.3.10.458
4ambDUDPutative glycosyl transferase/0.458
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.458
4ips1G4Mycocyclosin synthase1.14.21.90.458
4nbwNADShort-chain dehydrogenase/reductase SDR/0.458
1tqf32PBeta-secretase 13.4.23.460.457
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.457
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.457
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.457
2rcyNAPPyrroline-5-carboxylate reductase/0.457
3f03FMNPentaerythritol tetranitrate reductase/0.457
4q0kGA3Phytohormone-binding protein/0.457
5eb5FAD(R)-mandelonitrile lyase 14.1.2.100.457
1npvL27Gag-Pol polyprotein3.4.23.160.456
1rneC60Renin3.4.23.150.456
1y7lASN_LEU_ASN_ILECysteine synthase2.5.1.470.456
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.456
2g1s4IGRenin3.4.23.150.456
2givACOHistone acetyltransferase KAT8/0.456
2hk9NAPShikimate dehydrogenase (NADP(+))/0.456
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.456
3frqERYErythromycin resistance repressor protein/0.456
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.456
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3up5FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.456
4b65FADL-ornithine N(5)-monooxygenase/0.456
4g7gVFVLanosterol 14-alpha-demethylase/0.456
4xguADPPutative pachytene checkpoint protein 2/0.456
1culFOKAdenylate cyclase type 2/0.455
1culFOKAdenylate cyclase type 5/0.455
1qorNDPQuinone oxidoreductase 1/0.455
1x1cSAHC-20 methyltransferase/0.455
2he5NDPAldo-keto reductase family 1 member C211.1.10.455
2q5g1FAPeroxisome proliferator-activated receptor delta/0.455
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.455
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.455
3vqsJT1Genome polyprotein/0.455
4dxd9PCCell division protein FtsZ/0.455
4nakPBQ2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic2.7.7.600.455
4uyf73BBromodomain-containing protein 2/0.455
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.455
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.454
1ohhANPATP synthase subunit alpha, mitochondrial/0.454
1ohhANPATP synthase subunit beta, mitochondrial3.6.3.140.454
2pj4414Carboxypeptidase B/0.454
2z54AB1Gag-Pol polyprotein3.4.23.160.454
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.454
3jzdNADMaleylacetate reductase/0.454
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.454
3phjDHKShikimate dehydrogenase (NADP(+))/0.454
3tneRITCandidapepsin-13.4.23.240.454
3zuyTCHTransporter/0.454
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.454
4f5yC2EStimulator of interferon genes protein/0.454
4irnFADAnaB/0.454
4pl0ANPMicrocin-J25 export ATP-binding/permease protein McjD/0.454
4wriOKAOkadaic acid binding protein 2-alpha/0.454
5jscFADPutative acyl-CoA dehydrogenase/0.454
1bxoPP7Penicillopepsin-13.4.23.200.453
1u2rSO1Elongation factor 2/0.453
1udaUFGUDP-glucose 4-epimerase5.1.3.20.453
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.453
2ebaFADPutative glutaryl-CoA dehydrogenase/0.453
2gz8F3FOrf1a polyprotein/0.453
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.453
2wo7ASVIsopenicillin N synthase1.21.3.10.453
3ggoNAIPrephenate dehydrogenase/0.453
3orfNADDihydropteridine reductase1.5.1.340.453
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.452
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.452
1fm4DXCMajor pollen allergen Bet v 1-L/0.452
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
2dvlFADAcyl-CoA dehydrogenase/0.452
2xveFADPutative flavin-containing monooxygenase/0.452
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.452
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.452
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
4gl4NAIAlcohol dehydrogenase class-3/0.452
4twnB96Ephrin type-A receptor 32.7.10.10.452
1kkq471Peroxisome proliferator-activated receptor alpha/0.451
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.451
1xe65FPPlasmepsin-23.4.23.390.451
1xzqFONtRNA modification GTPase MnmE3.6.50.451
1z7yAA5Cysteine synthase 12.5.1.470.451
2a94AP0L-lactate dehydrogenase1.1.1.270.451
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
2g247IGRenin3.4.23.150.451
2ien017Gag-Pol polyprotein3.4.23.160.451
2p5uNADUDP-glucose 4-epimerase/0.451
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.451
3em3478Gag-Pol polyprotein3.4.23.160.451
3mjrAC2Deoxycytidine kinase2.7.1.740.451
3uylTYDProbable NDP-rhamnosyltransferase/0.451
4acuQN7Beta-secretase 13.4.23.460.451
4dpuAGSMevalonate diphosphate decarboxylase/0.451
4qaiFMNNADPH dehydrogenase/0.451
1bmfANPATP synthase subunit alpha, mitochondrial/0.450
1bmfANPATP synthase subunit beta, mitochondrial3.6.3.140.450
1t2cNAIL-lactate dehydrogenase1.1.1.270.450
1x1aSAMC-20 methyltransferase/0.450
1x1dSAHC-20 methyltransferase/0.450
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
2dftADPShikimate kinase2.7.1.710.450
2fzwNADAlcohol dehydrogenase class-31.1.1.10.450
2gv8NDPThiol-specific monooxygenase1.14.130.450
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.450
2ylzFADPhenylacetone monooxygenase1.14.13.920.450
3a1nNADNDP-sugar epimerase/0.450
3dxmN24Actin-related protein 3/0.450
4oztP1AEcdysone receptor, putative/0.450
4q71FADBifunctional protein PutA/0.450
4tm1FDAKtzI/0.450
5ejaTD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.450
5hwsNAP2-dehydropantoate 2-reductase/0.450
1qiqACCIsopenicillin N synthase1.21.3.10.449
2a87FADThioredoxin reductase1.8.1.90.449
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.449
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.449
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
4acxS8ZBeta-secretase 13.4.23.460.449
4bb3KKAIsopenicillin N synthase1.21.3.10.449
4egbNADdTDP-glucose 4,6-dehydratase/0.449
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.449
4m10ICDProstaglandin G/H synthase 21.14.99.10.449
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.449
1bim0QBRenin3.4.23.150.448
1f20FADNitric oxide synthase, brain1.14.13.390.448
1f8wFADNADH peroxidase1.11.1.10.448
1msmJE2Gag-Pol polyprotein3.4.23.160.448
1qjfACSIsopenicillin N synthase1.21.3.10.448
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.448
1vp6CMPCyclic nucleotide-gated potassium channel mll3241/0.448
2is0I03Beta-secretase 13.4.23.460.448
2npfMOUElongation factor 2/0.448
2op9WR1Orf1ab polyprotein/0.448
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.448
2y3rTRKTamL/0.448
3clsFADElectron transfer flavoprotein subunit alpha/0.448
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3ensENSCoagulation factor X3.4.21.60.448
3fcjFADNitroalkane oxidase1.7.3.10.448
3lpkZ76Beta-secretase 13.4.23.460.448
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.448
3to6LYS_CMCHistone acetyltransferase ESA1/0.448
3tr05GPGuanylate kinase/0.448
4eb7PLPCysteine desulfurase IscS 2/0.448
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.448
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.448
4i8vBHFCytochrome P450 1A11.14.14.10.448
5c1mCLRMu-type opioid receptor/0.448
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.448
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.447
1okkGCPSignal recognition particle protein/0.447
1okkGCPSignal recognition particle receptor FtsY/0.447
1opmIYGPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.447
1zioAP5Adenylate kinase/0.447
1zrzBI1Protein kinase C iota type2.7.11.130.447
2b4rAESGlyceraldehyde-3-phosphate dehydrogenase/0.447
2c12FADNitroalkane oxidase1.7.3.10.447
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.447
2ou2ACOHistone acetyltransferase KAT5/0.447
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.447
3kb1ADPIron-sulfur cluster carrier protein/0.447
3lzs017Gag-Pol polyprotein3.4.23.160.447
3nutSAHPrecorrin-3 methylase/0.447
3oibFDAPutative acyl-CoA dehydrogenase/0.447
3slkNDPPolyketide synthase extender module 2/0.447
3syiFADSulfide-quinone reductase/0.447
3zkpERBErythromycin C-12 hydroxylase1.14.13.1540.447
4du82P0Mevalonate diphosphate decarboxylase/0.447
4zp0DXCMultidrug transporter MdfA/0.447
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1drhNAPDihydrofolate reductase1.5.1.30.446
1e3eNAIAlcohol dehydrogenase 41.1.1.10.446
1i3mUD1UDP-glucose 4-epimerase/0.446
1nlmUD1UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase/0.446
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.446
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.446
1zeoC01Peroxisome proliferator-activated receptor gamma/0.446
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.446
2a92NAIL-lactate dehydrogenase/0.446
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.446
2x0iNAIMalate dehydrogenase/0.446
2xx91NFGlutamate receptor 2/0.446
3dh7FMNIsopentenyl-diphosphate delta-isomerase/0.446
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3qwbNDPProbable quinone oxidoreductase1.6.5.50.446
3tog079Gag-Pol polyprotein2.7.7.490.446
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.446
3wb2YGPUncharacterized protein MJ0488/0.446
4a802ANMajor pollen allergen Bet v 1-A/0.446
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.446
4e470N6Histone-lysine N-methyltransferase SETD72.1.1.430.446
4fn4NADShort chain dehydrogenase/0.446
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.446
4uymVOR14-alpha sterol demethylase Cyp51B/0.446
1e1qANPATP synthase subunit alpha, mitochondrial/0.445
1e1qANPATP synthase subunit beta, mitochondrial3.6.3.140.445
1i5eU5PUracil phosphoribosyltransferase/0.445
1mjaCOAHistone acetyltransferase ESA1/0.445
1nhhANPDNA mismatch repair protein MutL/0.445
1ptjSNDNAD(P) transhydrogenase subunit alpha part 11.6.1.20.445
1rdt570Peroxisome proliferator-activated receptor gamma/0.445
1yqzCOACoenzyme A disulfide reductase/0.445
2hdjNDPAldo-keto reductase family 1 member C2/0.445
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.445
3bk2U5PRibonuclease J/0.445
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3gwfNAPCyclohexanone monooxygenase/0.445
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.445
3ivgFG5Pantothenate synthetase6.3.2.10.445
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.445
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
4b78KGGBeta-secretase 13.4.23.460.445
4fv7E94Mitogen-activated protein kinase 12.7.11.240.445
4j0v1H7Beta-secretase 13.4.23.460.445
4ohwATPProtein clpf-1/0.445
4opgFDAConserved Archaeal protein/0.445
1cdoNADAlcohol dehydrogenase 11.1.1.10.444
1jedADPSulfate adenylyltransferase/0.444
1lquNDPNADPH-ferredoxin reductase FprA1.18.1.20.444
1tehNADAlcohol dehydrogenase class-31.1.1.10.444
1xq6NAPUncharacterized protein At5g02240/0.444
2d29FADAcyl-CoA dehydrogenase/0.444
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.444
2fznFADBifunctional protein PutA1.5.5.20.444
2gz7D3FOrf1a polyprotein/0.444
2vprTDCTetracycline repressor protein class H/0.444
2wu4HBPAcetylcholinesterase3.1.1.70.444
3br3ETHTH-type transcriptional regulator QacR/0.444
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.444
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.444
3itjFADThioredoxin reductase 11.8.1.90.444
3l6jZ90Alr2278 protein/0.444
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.444
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.444
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.444
3raiX85Cyclin-dependent kinase 22.7.11.220.444
3sdkP3NProteasome subunit beta type-53.4.25.10.444
3sdkP3NProteasome subunit beta type-63.4.25.10.444
3vt8YI3Vitamin D3 receptor/0.444
4frkDWDBeta-secretase 13.4.23.460.444
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.444
4r7uUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.444
4yaoFMNNADPH--cytochrome P450 reductase/0.444
5a0yCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.444
5a0yCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.444
5a3bAPRSIR2 family protein/0.444
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.444
1cf3FADGlucose oxidase1.1.3.40.443
1e79ATPATP synthase subunit alpha, mitochondrial/0.443
1e79ATPATP synthase subunit beta, mitochondrial3.6.3.140.443
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.443
1uzwCDHIsopenicillin N synthase1.21.3.10.443
2c27ACOMycothiol acetyltransferase2.3.1.1890.443
2cftPLPPyridoxal phosphate phosphatase/0.443
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.443
2y3sTIRTamL/0.443
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.443
3g70A5TRenin3.4.23.150.443
3gvhNADMalate dehydrogenase/0.443
3h2sNDPPutative NADH-flavin reductase/0.443
3hx4ANPCalmodulin-domain protein kinase 1/0.443
3mj4FADUDP-galactopyranose mutase/0.443
3rtnRTNBeta-secretase 13.4.23.460.443
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.443
3zoiM2WIsopenicillin N synthase1.21.3.10.443
4dd8BATDisintegrin and metalloproteinase domain-containing protein 83.4.240.443
4dpf0LGBeta-secretase 13.4.23.460.443
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.443
4mlp2CXCryptochrome-2/0.443
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.443
5irnADPNucleotide binding oligomerization domain containing 2/0.443
1ae1NAPTropinone reductase 1/0.442
1amoFMNNADPH--cytochrome P450 reductase/0.442
1ep3FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.442
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.442
1k6tXN1Gag-Pol polyprotein3.4.23.160.442
1qrpHH0Pepsin A-43.4.23.10.442
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.442
1xl5190Gag-Pol polyprotein3.4.23.160.442
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.442
2gjnFMNNitronate monooxygenase1.13.12.160.442
2hfpNSIPeroxisome proliferator-activated receptor gamma/0.442
2j83BATUlilysin3.4.240.442
2rhgIGPTryptophan synthase alpha chain/0.442
2rqfJH3Hemolymph juvenile hormone binding protein/0.442
2uxoTACHTH-type transcriptional regulator TtgR/0.442
2v7qATPATP synthase subunit alpha, mitochondrial/0.442
2v7qATPATP synthase subunit beta, mitochondrial3.6.3.140.442
2wedPP6Penicillopepsin-13.4.23.200.442
2y65ADPKinesin heavy chain/0.442
3a6qFMNFMN-binding protein/0.442
3c212BADNA integrity scanning protein DisA/0.442
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3fznD7KBenzoylformate decarboxylase4.1.1.70.442
3hyg099A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.442
3pndFADFAD:protein FMN transferase/0.442
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.442
3v2uATPProtein GAL3/0.442
4a862ANMajor pollen allergen Bet v 1-A/0.442
4dfg0JVGag-Pol polyprotein3.4.23.160.442
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.442
4mdhNADMalate dehydrogenase, cytoplasmic1.1.1.370.442
5f8eSAHPossible transcriptional regulatory protein/0.442
1beuIPLTryptophan synthase alpha chain/0.441
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.441
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1fy7COAHistone acetyltransferase ESA1/0.441
1kp2ATPArgininosuccinate synthase6.3.4.50.441
1nooCAHCamphor 5-monooxygenase1.14.15.10.441
2am22LGUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.441
2bjfDXCCholoylglycine hydrolase3.5.1.240.441
2cv2GSUGlutamate--tRNA ligase6.1.1.170.441
2wf4ZY4Beta-secretase 13.4.23.460.441
2y4gTIRTamL/0.441
3d8bADPFidgetin-like protein 13.6.40.441
3gqvNAPEnoyl reductase LovC10.441
3h8bNSYCathepsin L13.4.22.150.441
3kkzSAMUncharacterized protein/0.441
3lpiZ74Beta-secretase 13.4.23.460.441
3nbvANPKetohexokinase/0.441
3p2oNADBifunctional protein FolD/0.441
3r83Z14Cyclin-dependent kinase 22.7.11.220.441
4asuADPATP synthase subunit alpha, mitochondrial/0.441
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
4djaFAD(6-4) photolyase/0.441
4ejmNAPPutative zinc-binding dehydrogenase/0.441
4kbyC2EStimulator of interferon genes protein/0.441
4nmdFDABifunctional protein PutA/0.441
4r20AERCytochrome P450 family 17 polypeptide 2/0.441
4rquNADAlcohol dehydrogenase class-P/0.441
3sn6P0GBeta-2 adrenergic receptor/0.441
1a72PADAlcohol dehydrogenase E chain1.1.1.10.440
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.440
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.440
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1omoNADAlanine dehydrogenase/0.440
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.440
1t87CAMCamphor 5-monooxygenase1.14.15.10.440
1w0kADPATP synthase subunit alpha, mitochondrial/0.440
1w0kADPATP synthase subunit beta, mitochondrial3.6.3.140.440
1xvaSAMGlycine N-methyltransferase2.1.1.200.440
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.440
2g1n1IGRenin3.4.23.150.440
3c1y2BADNA integrity scanning protein DisA/0.440
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.440
3d91REMRenin3.4.23.150.440
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.440
3h3r14HCollagen type IV alpha-3-binding protein/0.440
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
3oev3OEProteasome subunit beta type-53.4.25.10.440
3oev3OEProteasome subunit beta type-63.4.25.10.440
3qlsNDPDihydrofolate reductase1.5.1.30.440
3v3m0ENReplicase polyprotein 1a3.4.19.120.440
3vt7VDXVitamin D3 receptor/0.440
3wagTYDGlycosyltransferase/0.440
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.440
4a4qUX9Pol protein/0.440
4b1rITCTetracycline repressor protein class D/0.440
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.440
4bfwZVWPantothenate kinase2.7.1.330.440
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.440
4dbzNDPPutative ketoacyl reductase1.3.10.440
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.440
4h1vGNPDynamin-1-like protein3.6.5.50.440
4i8zG08Gag-Pol polyprotein3.4.23.160.440
4iv6FDAIsovaleryl-CoA dehydrogenase/0.440
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.440
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.440
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.440