Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2eh4 | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2eh4 | SAH | Diphthine synthase | / | 1.000 | |
| 2p9d | SAH | Diphthine synthase | / | 0.874 | |
| 1wng | SAH | Diphthine synthase | / | 0.872 | |
| 2pca | SAH | Diphthine synthase | / | 0.866 | |
| 2e07 | SAH | Diphthine synthase | / | 0.860 | |
| 2huq | SAH | Diphthine synthase | / | 0.859 | |
| 2huv | SAH | Diphthine synthase | / | 0.857 | |
| 2owg | SAH | Diphthine synthase | / | 0.822 | |
| 2ejj | SAH | Diphthine synthase | / | 0.819 | |
| 2dsh | SAH | Diphthine synthase | / | 0.807 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.801 | |
| 2el0 | SAH | Diphthine synthase | / | 0.786 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.783 | |
| 2e4n | SAH | Diphthine synthase | / | 0.779 | |
| 2dxx | SAH | Diphthine synthase | / | 0.776 | |
| 2p6i | SAH | Diphthine synthase | / | 0.762 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.759 | |
| 2z6r | SAH | Diphthine synthase | / | 0.753 | |
| 2pck | SAH | Diphthine synthase | / | 0.751 | |
| 2p5c | SAH | Diphthine synthase | / | 0.749 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.743 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.731 | |
| 2pch | SAH | Diphthine synthase | / | 0.731 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.722 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.722 | |
| 2e8q | SAH | Diphthine synthase | / | 0.720 | |
| 2el3 | SAH | Diphthine synthase | / | 0.719 | |
| 2hux | SAH | Diphthine synthase | / | 0.716 | |
| 2e8r | SAH | Diphthine synthase | / | 0.710 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.701 | |
| 2dsg | SAH | Diphthine synthase | / | 0.700 | |
| 2e17 | SAH | Diphthine synthase | / | 0.698 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.698 | |
| 2e7r | SAH | Diphthine synthase | / | 0.694 | |
| 2eld | SAH | Diphthine synthase | / | 0.693 | |
| 2owu | SAH | Diphthine synthase | / | 0.693 | |
| 2dxw | SAH | Diphthine synthase | / | 0.692 | |
| 2eeq | SAH | Diphthine synthase | / | 0.692 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.689 | |
| 2dsi | SAH | Diphthine synthase | / | 0.686 | |
| 2p5f | SAH | Diphthine synthase | / | 0.685 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.678 | |
| 2pcg | SAH | Diphthine synthase | / | 0.677 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.676 | |
| 2e15 | SAH | Diphthine synthase | / | 0.675 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.668 | |
| 2en5 | SAH | Diphthine synthase | / | 0.666 | |
| 2dxv | SAH | Diphthine synthase | / | 0.665 | |
| 2e08 | SAH | Diphthine synthase | / | 0.665 | |
| 1vce | SAH | Diphthine synthase | / | 0.661 | |
| 2hut | SAH | Diphthine synthase | / | 0.660 | |
| 2owk | SAH | Diphthine synthase | / | 0.655 | |
| 2pci | SAH | Diphthine synthase | / | 0.652 | |
| 2eni | SAH | Diphthine synthase | / | 0.650 | |
| 2e8s | SAH | Diphthine synthase | / | 0.649 | |
| 2egb | SAH | Diphthine synthase | / | 0.646 | |
| 2p6k | SAH | Diphthine synthase | / | 0.641 | |
| 2ejk | SAH | Diphthine synthase | / | 0.637 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.635 | |
| 2emr | SAH | Diphthine synthase | / | 0.632 | |
| 2e8h | SAH | Diphthine synthase | / | 0.630 | |
| 2eka | SAH | Diphthine synthase | / | 0.626 | |
| 2pcm | SAH | Diphthine synthase | / | 0.626 | |
| 2ele | SAH | Diphthine synthase | / | 0.625 | |
| 2p6l | SAH | Diphthine synthase | / | 0.620 | |
| 2p2x | SAH | Diphthine synthase | / | 0.619 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.616 | |
| 2emu | SAH | Diphthine synthase | / | 0.602 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.600 | |
| 2dek | SAH | Diphthine synthase | / | 0.594 | |
| 2owf | SAH | Diphthine synthase | / | 0.593 | |
| 2ehl | SAH | Diphthine synthase | / | 0.582 | |
| 2p6d | SAH | Diphthine synthase | / | 0.580 | |
| 2egs | SAH | Diphthine synthase | / | 0.579 | |
| 2ejz | SAH | Diphthine synthase | / | 0.578 | |
| 2egl | SAH | Diphthine synthase | / | 0.575 | |
| 2e16 | SAH | Diphthine synthase | / | 0.572 | |
| 2owv | SAH | Diphthine synthase | / | 0.572 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.497 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.494 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.493 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.489 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.488 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.487 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.487 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.484 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.483 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.483 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.483 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.482 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.482 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.482 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.481 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.481 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.480 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.480 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.479 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.478 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.478 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.478 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.477 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.476 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.476 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.475 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.475 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.474 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.472 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.472 | |
| 3pnd | FAD | FAD:protein FMN transferase | / | 0.472 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.472 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.472 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.472 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.471 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.470 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.470 | |
| 3a3g | DLZ | Lumazine protein | / | 0.470 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.470 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.470 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.469 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.469 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.469 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.469 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.468 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.468 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.467 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.467 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.467 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.466 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.466 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.466 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.466 | |
| 2y3s | TIR | TamL | / | 0.466 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.466 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.466 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.465 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.465 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.465 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.465 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.465 | |
| 4yqf | GDP | Septin-9 | / | 0.465 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.464 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.464 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.464 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.463 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.463 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.463 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.463 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.462 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.462 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.461 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.461 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.461 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.461 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.461 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.461 | |
| 3pfd | FDA | Acyl-CoA dehydrogenase FadE25 | / | 0.461 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.461 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.461 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.461 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.461 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.460 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.460 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.460 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.460 | |
| 2y3r | TIR | TamL | / | 0.460 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.460 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.460 | |
| 1e79 | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.459 | |
| 1e79 | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.459 | |
| 1h8h | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.459 | |
| 1h8h | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.459 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.459 | |
| 2gz7 | D3F | Orf1a polyprotein | / | 0.459 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.459 | |
| 3vn2 | TLS | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.459 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.459 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.458 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.458 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.458 | |
| 3d5m | 4MS | Genome polyprotein | 2.7.7.48 | 0.458 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.458 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.458 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.458 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.458 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.457 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 2op9 | WR1 | Orf1ab polyprotein | / | 0.457 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.457 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.457 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.457 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.457 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.457 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.457 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.456 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.456 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.456 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.456 | |
| 1zio | AP5 | Adenylate kinase | / | 0.455 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.455 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.455 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.455 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.455 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.455 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.455 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.454 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.454 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.454 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.454 | |
| 2xfi | XFI | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.454 | |
| 4nak | PBQ | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic | 2.7.7.60 | 0.454 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.454 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.454 | |
| 1bmf | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.453 | |
| 1bmf | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.453 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.453 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.453 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.453 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.453 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.453 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.452 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.452 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.452 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.452 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.452 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.452 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4qxr | 1YE | Stimulator of interferon genes protein | / | 0.452 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.451 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 3rai | X85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.451 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.451 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.450 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.450 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.450 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.450 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.450 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.450 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.450 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.450 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.450 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.450 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.450 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.449 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.449 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.449 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.449 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.449 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3ut5 | LOC | Tubulin beta chain | / | 0.449 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4dxd | 9PC | Cell division protein FtsZ | / | 0.449 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.449 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.448 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.448 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.448 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.448 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.448 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2x0i | NAI | Malate dehydrogenase | / | 0.448 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.448 | |
| 2y3r | TRK | TamL | / | 0.448 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.448 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.448 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.448 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.448 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.448 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.448 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.448 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.448 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.447 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.447 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.447 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.447 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.447 | |
| 2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.447 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.447 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.447 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.447 | |
| 3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1 | / | 0.447 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1-binding protein 1 | / | 0.447 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.447 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.447 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.446 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.446 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.446 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.446 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.446 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.446 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.446 | |
| 3swq | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.446 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.446 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4kb9 | G79 | Protease | / | 0.446 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.446 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.446 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.445 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.445 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.445 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.445 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.445 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.445 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.445 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.445 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.445 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.445 | |
| 4irn | FAD | AnaB | / | 0.445 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.445 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 1opm | IYG | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.444 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.444 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.444 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.444 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.444 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.444 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.444 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.444 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 4ohw | ATP | Protein clpf-1 | / | 0.444 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.443 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.443 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.443 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.443 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.443 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2wec | PP5 | Penicillopepsin-1 | 3.4.23.20 | 0.443 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.443 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.443 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.443 | |
| 2zts | ADP | Uncharacterized protein | / | 0.443 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.443 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.443 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.443 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.443 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4e47 | 0N6 | Histone-lysine N-methyltransferase SETD7 | 2.1.1.43 | 0.443 | |
| 4q4k | FMN | Uncharacterized protein | / | 0.443 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.442 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.442 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.442 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.442 | |
| 1vp6 | CMP | Cyclic nucleotide-gated potassium channel mll3241 | / | 0.442 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.442 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.442 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.442 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3u9e | COA | Lmo1369 protein | / | 0.442 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.442 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.442 | |
| 3zuy | TCH | Transporter | / | 0.442 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.442 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.441 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.441 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.441 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.441 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.441 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.441 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.441 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.441 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.441 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.441 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.441 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4l4x | NDP | AmphI | / | 0.441 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.441 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.441 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.441 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.440 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.440 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.440 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.440 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.440 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.440 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.440 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.440 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.440 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3u4o | 08E | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.440 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.440 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.440 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.440 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.440 |