sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2eer | NAD | NAD-dependent alcohol dehydrogenase | 1.1.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2eer | NAD | NAD-dependent alcohol dehydrogenase | 1.1.1.1 | 1.000 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.452 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.451 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.449 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.447 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.446 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.446 | |
| 5doz | NDP | JamJ | / | 0.446 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.445 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.444 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.443 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.442 | |
| 3o9z | NAD | Lipopolysaccaride biosynthesis protein wbpB | / | 0.441 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.440 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.440 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.440 |