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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2eckADPAdenylate kinase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2eckADPAdenylate kinase/1.000
1akeAP5Adenylate kinase/0.755
4x8oAP5Adenylate kinase/0.606
4jloADPAdenylate kinase/0.600
4qbiAP5Adenylate kinase/0.597
1p3jAP5Adenylate kinase/0.596
2osbAP5Adenylate kinase/0.595
3dl0AP5Adenylate kinase/0.589
3tlxADPAdenylate kinase 2/0.589
3hpqAP5Adenylate kinase/0.587
2oo7AP5Adenylate kinase/0.585
3dkvAP5Adenylate kinase/0.584
4jl5ADPAdenylate kinase/0.582
4w5jAP5Adenylate kinase/0.578
4qbhAP5Adenylate kinase/0.576
4nu0AP5Adenylate kinase/0.565
1ankANPAdenylate kinase/0.562
4cf7ADPAdenylate kinase/0.562
1e4yAP5Adenylate kinase/0.559
4jl6ADPAdenylate kinase/0.556
4x8lAP5Adenylate kinase/0.554
2rgxAP5Adenylate kinase/0.547
2akyAP5Adenylate kinase/0.537
4mkfAP5Adenylate kinase/0.537
3s79ASDAromatase1.14.14.140.520
4ikeADPAdenylate kinase/0.518
2x0rNADMalate dehydrogenase/0.506
4ma628EAra h 8 allergen/0.503
2daaDCSD-alanine aminotransferase2.6.1.210.496
4f6w0SSCyclin-dependent kinase 82.7.11.220.492
5cwa0GAAnthranilate synthase component 14.1.3.270.490
1psdNADD-3-phosphoglycerate dehydrogenase1.1.1.950.488
2bunFADAppA protein/0.487
2x7hPFNProstaglandin reductase 310.485
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.485
4ebfNADPhosphonate dehydrogenase1.20.1.10.483
1x8b824Wee1-like protein kinase2.7.10.20.482
2ql6ADPNicotinamide riboside kinase 1/0.482
2hfuMEVMevalonate kinase/0.480
2q6bHR23-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.480
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.480
3ed1GA3Gibberellin receptor GID1/0.479
2wq7FADRE11660p/0.476
4d7eFADPutative lysine-N-oxygenase/0.476
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.476
4loh1SYStimulator of interferon genes protein/0.476
3otwCOAPhosphopantetheine adenylyltransferase/0.474
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.474
1iqrFADDeoxyribodipyrimidine photo-lyase4.1.99.30.472
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.472
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.470
3crlANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.470
3fgoACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.470
3v49PK0Androgen receptor/0.470
4e5kNADPhosphonate dehydrogenase1.20.1.10.470
4i7fNVEGag-Pol polyprotein2.7.7.490.470
2q5oTPWIndole-3-pyruvate decarboxylase4.1.1.740.469
2rkvZBATrichothecene 3-O-acetyltransferase/0.469
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
2ydd2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.468
3fql79ZGenome polyprotein2.7.7.480.468
3p62FMNPentaerythritol tetranitrate reductase/0.468
4n49MGTCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 12.1.1.570.468
4wouGDPPhosphoenolpyruvate carboxykinase [GTP]/0.468
5j23A2RPutative 2-hydroxyacid dehydrogenase/0.468
1lhwESMSex hormone-binding globulin/0.467
1v0cACOAAC(6')-Ib/0.467
1sxjADPReplication factor C subunit 5/0.466
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.466
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.466
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.466
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.466
4appN53Serine/threonine-protein kinase PAK 42.7.11.10.466
4dpwAGSMevalonate diphosphate decarboxylase/0.466
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.465
1svmATPLarge T antigen3.6.40.465
1u3dFADCryptochrome-1/0.465
2olrATPPhosphoenolpyruvate carboxykinase (ATP)/0.465
3fskRO6Mitogen-activated protein kinase 14/0.465
3gg0FMNUncharacterized protein/0.465
3wb2YGPUncharacterized protein MJ0488/0.465
4i6gFADCryptochrome-2/0.465
2aazCB3Thymidylate synthase2.1.1.450.464
2j07FADDeoxyribodipyrimidine photo-lyase4.1.99.30.464
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
2p2xSAHDiphthine synthase/0.464
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.464
5kghACOPredicted acetyltransferase/0.464
5kgpACOPredicted acetyltransferase/0.464
2v5aLZLBiotin carboxylase6.3.4.140.463
4l9kEHFSerum albumin/0.463
1cs4FOKAdenylate cyclase type 2/0.462
1cs4FOKAdenylate cyclase type 5/0.462
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.462
3dxmN24Actin-related protein 3/0.462
1g4tFTPThiamine-phosphate synthase/0.461
1ih8APCNH(3)-dependent NAD(+) synthetase6.3.1.50.461
2xpwOTCTetracycline repressor protein class D/0.461
2zshGA3Gibberellin receptor GID1A30.461
3a62STURibosomal protein S6 kinase beta-12.7.11.10.461
3bazNAPHydroxyphenylpyruvate reductase1.1.1.2370.461
3k145352-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.461
3nmpPYVAbscisic acid receptor PYL2/0.461
3p23ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.461
5kf1ACOPredicted acetyltransferase/0.461
1g0rTHMGlucose-1-phosphate thymidylyltransferase/0.460
1tduDURThymidylate synthase/0.460
2qr1ADP5'-AMP-activated protein kinase subunit gamma/0.460
2xb5I7TTetracycline repressor protein class D/0.460
2xh9J01Uncharacterized protein/0.460
3p97SAMGenome polyprotein2.1.1.560.460
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
4i02CMPcAMP-activated global transcriptional regulator CRP/0.460
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.459
1f9aATPNicotinamide-nucleotide adenylyltransferase/0.459
1mgoNADAlcohol dehydrogenase E chain1.1.1.10.459
1ybaNADD-3-phosphoglycerate dehydrogenase1.1.1.950.459
2ejvNADL-threonine 3-dehydrogenase/0.459
2iyiFMNAppA, antirepressor of ppsR, sensor of blue light/0.459
2jlbUDMUncharacterized protein/0.459
4egnTWOCytochrome P450/0.459
5cdsNAJAlcohol dehydrogenase E chain1.1.1.10.459
1dc6NADGlyceraldehyde-3-phosphate dehydrogenase A/0.458
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.458
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.458
3f03FMNPentaerythritol tetranitrate reductase/0.458
3qw4U5POrotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative/0.458
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.458
4ai8DZAHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.458
4dbzNDPPutative ketoacyl reductase1.3.10.458
4weqNAPNAD-dependent dehydrogenase/0.458
1fdoMGDFormate dehydrogenase H1.1.99.330.457
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.457
1mezGDPAdenylosuccinate synthetase isozyme 1/0.457
1rbyKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.457
3zeiAWHO-acetylserine sulfhydrylase/0.457
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
4lgaA2OAbscisic acid receptor PYL2/0.457
4qedNAPElxO/0.457
4tuvCPZCytochrome P450 1191.140.457
1lolXMPOrotidine 5'-phosphate decarboxylase4.1.1.230.456
2qimZEAClass 10 plant pathogenesis-related protein/0.456
2tohHBITyrosine 3-monooxygenase1.14.16.20.456
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.456
3eblGA4Gibberellin receptor GID1/0.456
3fp0FP015-O-acetyltransferase/0.456
3to3ATPPetrobactin biosynthesis protein AsbB/0.456
1bwlFMNNADPH dehydrogenase 11.6.99.10.455
1ja1NAPNADPH--cytochrome P450 reductase/0.455
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.455
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.455
2j08FADDeoxyribodipyrimidine photo-lyase4.1.99.30.455
2vprTDCTetracycline repressor protein class H/0.455
4ansVGHALK tyrosine kinase receptor2.7.10.10.455
4bewACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.455
4e2bFMNDehydrogenase/0.455
4gk3L87Ephrin type-A receptor 32.7.10.10.455
4s26SAHPhosphomethylpyrimidine synthase, chloroplastic4.1.99.170.455
2bpoNAPNADPH--cytochrome P450 reductase/0.454
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.454
2gqtFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.454
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.454
3au8NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.454
3c14FOKAdenylate cyclase type 2/0.454
3c14FOKAdenylate cyclase type 5/0.454
3f3sNADLambda-crystallin homolog/0.454
3lm8VIBThiamine pyrophosphokinase2.7.6.20.454
3nxoD2BDihydrofolate reductase1.5.1.30.454
4bb432WEphrin type-B receptor 42.7.10.10.454
4e37NDPCatalase1.11.1.60.454
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.454
4qaiFMNNADPH dehydrogenase/0.454
4x30T44Thyroxine-binding globulin/0.454
4yswFADXanthine dehydrogenase/oxidase/0.454
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.454
5ikrID8Prostaglandin G/H synthase 21.14.99.10.454
1a72PADAlcohol dehydrogenase E chain1.1.1.10.453
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.453
1hetNADAlcohol dehydrogenase E chain1.1.1.10.453
1rszDIHPurine nucleoside phosphorylase2.4.2.10.453
2a1mCAMCamphor 5-monooxygenase1.14.15.10.453
2eklNADD-3-phosphoglycerate dehydrogenase/0.453
2iypA2P6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.453
2o12FMNChorismate synthase/0.453
2od7A1RNAD-dependent protein deacetylase HST23.5.10.453
2uxhQUEHTH-type transcriptional regulator TtgR/0.453
2zpaADPtRNA(Met) cytidine acetyltransferase TmcA/0.453
3cgdCOACoenzyme A disulfide reductase/0.453
3s1dZIRCytokinin dehydrogenase 11.5.99.120.453
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.453
4kin1M8Mitogen-activated protein kinase 14/0.453
4zlaBESCytosol aminopeptidase3.4.11.10.453
1blzACVIsopenicillin N synthase1.21.3.10.452
1daaPLPD-alanine aminotransferase2.6.1.210.452
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1o76CAMCamphor 5-monooxygenase1.14.15.10.452
2jb4A14Isopenicillin N synthase1.21.3.10.452
3h4vDVPPteridine reductase 11.5.1.330.452
3ik6HCZGlutamate receptor 2/0.452
3k3bADPKinesin-like protein KIF11/0.452
3oibFDAPutative acyl-CoA dehydrogenase/0.452
3qe2NAPNADPH--cytochrome P450 reductase/0.452
3ska053Genome polyprotein2.7.7.480.452
3uf6CODLmo1369 protein/0.452
4a7b3W5Collagenase 33.4.240.452
4iakADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
4idgNADPutative UDP-glucose 4-epimerase/0.452
4qxp1YEStimulator of interferon genes protein/0.452
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.452
5kgjACOPredicted acetyltransferase/0.452
5kj6NAJAlcohol dehydrogenase E chain1.1.1.10.452
1o5iNAD3-oxoacyl-(Acyl carrier protein) reductase/0.451
1tllNAPNitric oxide synthase, brain1.14.13.390.451
2qqfA1RNAD-dependent protein deacetylase HST23.5.10.451
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.451
2ym1NAPPhenylacetone monooxygenase1.14.13.920.451
3ibqATPPyridoxal kinase/0.451
3mgdACOPredicted acetyltransferase/0.451
4dwvNAJAlcohol dehydrogenase E chain1.1.1.10.451
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.451
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.451
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.451
4jxxATPGlutamine--tRNA ligase6.1.1.180.451
4xyeNADFormate dehydrogenase/0.451
5dp2NAPCurF/0.451
1bifAGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.450
2bu9HFVIsopenicillin N synthase1.21.3.10.450
2przOMPOrotate phosphoribosyltransferase 12.4.2.100.450
2q5qTPWIndole-3-pyruvate decarboxylase4.1.1.740.450
2rg6287Mitogen-activated protein kinase 14/0.450
2vojNADAlanine dehydrogenase1.4.1.10.450
2yxuATPPyridoxal kinase2.7.1.350.450
2zsiGA4Gibberellin receptor GID1A30.450
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.450
3frqERYErythromycin resistance repressor protein/0.450
3kb1ADPIron-sulfur cluster carrier protein/0.450
3lqfNADGalactitol dehydrogenase/0.450
3nbzGTPGTP-binding nuclear protein Ran/0.450
3zc3NAPFerredoxin--NADP reductase1.18.1.20.450
4azmT4BFatty acid-binding protein, epidermal/0.450
4gk2L66Ephrin type-A receptor 32.7.10.10.450
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.450
4xgxADPFAD:protein FMN transferase/0.450
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.450
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.449
1hvyD16Thymidylate synthase2.1.1.450.449
1mczRMNBenzoylformate decarboxylase4.1.1.70.449
2cahNDPCatalase1.11.1.60.449
2iviACWIsopenicillin N synthase1.21.3.10.449
2p5uNADUDP-glucose 4-epimerase/0.449
2qocANPEphrin type-A receptor 32.7.10.10.449
2tpsTPSThiamine-phosphate synthase/0.449
2x3nFADProbable FAD-dependent monooxygenase/0.449
2x9fX9FEphrin type-B receptor 42.7.10.10.449
3lfcZ86Mitogen-activated protein kinase 14/0.449
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.449
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.449
3w6hAZMCarbonic anhydrase 14.2.1.10.449
4eh60ONMitogen-activated protein kinase 14/0.449
4xguADPPutative pachytene checkpoint protein 2/0.449
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.449
5kf9ACOPredicted acetyltransferase/0.449
1dnpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.448
1korANPArgininosuccinate synthase/0.448
1obnASVIsopenicillin N synthase1.21.3.10.448
1q1rFADPutidaredoxin reductase1.18.1.50.448
1q43CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2/0.448
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2acxANPG protein-coupled receptor kinase 62.7.11.160.448
2ejjSAHDiphthine synthase/0.448
2eudGCQRibonucleoside-diphosphate reductase large chain 11.17.4.10.448
2hr8SAHDiphthine synthase/0.448
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.448
2po7CHDFerrochelatase, mitochondrial4.99.1.10.448
3cseN22Uncharacterized protein/0.448
3gfyFMNUncharacterized protein/0.448
3oiaA31Camphor 5-monooxygenase1.14.15.10.448
3t1tGDPProbable gliding protein mglA/0.448
4jc51K5Stimulator of interferon genes protein/0.448
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
4v02ATPSite-determining protein/0.448
1esvLARActin, alpha skeletal muscle/0.447
1hdrNADDihydropteridine reductase1.5.1.340.447
1jx2ADPMyosin-2 heavy chain/0.447
1nooCAHCamphor 5-monooxygenase1.14.15.10.447
1oc1ASVIsopenicillin N synthase1.21.3.10.447
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.447
1ytmATPPhosphoenolpyruvate carboxykinase (ATP)/0.447
2bueCOAAAC(6')-Ib/0.447
2p9cNAID-3-phosphoglycerate dehydrogenase1.1.1.950.447
2y6o1N1Ephrin type-A receptor 42.7.10.10.447
3k2hLYABifunctional dihydrofolate reductase-thymidylate synthase/0.447
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.447
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.447
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.447
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.447
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.447
3tdl11DSerum albumin/0.447
3zkyWT4Isopenicillin N synthase1.21.3.10.447
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4l9q9TPSerum albumin/0.447
4lk3NADUDP-glucuronic acid decarboxylase 14.1.1.350.447
5a3bAPRSIR2 family protein/0.447
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.446
1qjfACSIsopenicillin N synthase1.21.3.10.446
1wpgADPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.446
2nniMTKCytochrome P450 2C8/0.446
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.446
2py7ATPPhosphoenolpyruvate carboxykinase (ATP)/0.446
3fr4F8AFatty acid-binding protein, adipocyte/0.446
3gbuATPUncharacterized sugar kinase PH14592.7.10.446
3ijrNADOxidoreductase, short chain dehydrogenase/reductase family/0.446
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.446
3kybFADUDP-galactopyranose mutase5.4.99.90.446
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.446
3o0qADNVitamin B12-dependent ribonucleotide reductase/0.446
3r9iADPSeptum site-determining protein MinD/0.446
3x2vATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4brgGNPEctonucleoside triphosphate diphosphohydrolase I/0.446
4e09ACPPlasmid partitioning protein ParF/0.446
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.446
4hwkNAPSepiapterin reductase1.1.1.1530.446
4jicFMNGTN Reductase/0.446
4jk4DIUSerum albumin/0.446
4r1lADPPhenylacetate-coenzyme A ligase/0.446
4wjiNAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase/0.446
5fs9FADApoptosis-inducing factor 1, mitochondrial1.1.10.446
5ftcADPTPR domain protein/0.446
5kf8ACOPredicted acetyltransferase/0.446
5l3rGCPCell division protein FtsY homolog, chloroplastic/0.446
1bwkFMNNADPH dehydrogenase 11.6.99.10.445
1cbqRE9Cellular retinoic acid-binding protein 2/0.445
1d7yFADFerredoxin reductase/0.445
1i44ACPInsulin receptor2.7.10.10.445
1kqfMGDFormate dehydrogenase, nitrate-inducible, major subunit1.1.5.60.445
1t88CAMCamphor 5-monooxygenase1.14.15.10.445
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.445
2dteNAIGlucose 1-dehydrogenase related protein/0.445
2gv8FADThiol-specific monooxygenase1.14.130.445
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
2jn3JN3Fatty acid-binding protein, liver/0.445
2wqeADPAurora kinase A2.7.11.10.445
2z6rSAHDiphthine synthase/0.445
3drcMTXDihydrofolate reductase1.5.1.30.445
3icsADPCoenzyme A disulfide reductase/0.445
3iphG11Mitogen-activated protein kinase 14/0.445
3owj1ELCasein kinase II subunit alpha2.7.11.10.445
4h1m0YJProtein-tyrosine kinase 2-beta2.7.10.20.445
4iji99TGlutathione S-transferase-like protein YibF/0.445
4kiq1RAMitogen-activated protein kinase 14/0.445
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
5dozNDPJamJ/0.445
1e7qNAPGDP-L-fucose synthase/0.444
1g9aBABBotulinum neurotoxin type B3.4.24.690.444
1gjrNAPFerredoxin--NADP reductase1.18.1.20.444
1nzdUPGDNA beta-glucosyltransferase/0.444
1t2cNAIL-lactate dehydrogenase1.1.1.270.444
1w7iADPUnconventional myosin-Va/0.444
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.444
2dwpACP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.444
2j09FADDeoxyribodipyrimidine photo-lyase4.1.99.30.444
2owuSAHDiphthine synthase/0.444
2rhrEMOPutative ketoacyl reductase1.3.10.444
2uyyNA7Putative oxidoreductase GLYR110.444
2vn0TDZCytochrome P450 2C8/0.444
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.444
3d8bADPFidgetin-like protein 13.6.40.444
3fgoCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.444
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.444
3u9eCOALmo1369 protein/0.444
3vi7CBDHematopoietic prostaglandin D synthase/0.444
4j0s1H3Bromodomain-containing protein 4/0.444
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
4lsmNADGlyceraldehyde-3-phosphate dehydrogenase/0.444
4nh0ATPESX secretion system protein EccC/0.444
4pd6URINucleoside permease/0.444
4u0mGTPCyclic GMP-AMP synthase/0.444
4uyg73BBromodomain-containing protein 2/0.444
4uymVOR14-alpha sterol demethylase Cyp51B/0.444
5cdgNAJAlcohol dehydrogenase E chain1.1.1.10.444
1bsvNDPGDP-L-fucose synthase/0.443
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.443
1dr3HBIDihydrofolate reductase1.5.1.30.443
1h63FMNPentaerythritol tetranitrate reductase/0.443
1hlk113Metallo-beta-lactamase type 2/0.443
1jpaANPEphrin type-B receptor 22.7.10.10.443
1rywEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.443
1w06W05Isopenicillin N synthase1.21.3.10.443
1xddAAYIntegrin alpha-L/0.443
2gmjFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.443
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.443
2o1vADPEndoplasmin/0.443
2qo7ANPEphrin type-A receptor 32.7.10.10.443
2wd4TBVAscorbate peroxidase/0.443
2yfxVGHALK tyrosine kinase receptor2.7.10.10.443
2zvcSAHPrecorrin-3 C17-methyltransferase/0.443
3hyg099A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.443
3sptUD1Bifunctional protein GlmU/0.443
3sxnCOAN-acetyltransferase Eis/0.443
3zoiM2WIsopenicillin N synthase1.21.3.10.443
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
4ead0NPThymidine phosphorylase2.4.2.40.443
4ev0CMPCyclic AMP receptor protein/0.443
4h6rFDAProline dehydrogenase/0.443
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.443
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.443
4jx1CAHCamphor 5-monooxygenase1.14.15.10.443
4pl3ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.443
4qvhCOAPhosphopantetheinyl transferase PptT (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrier protein]pantetheinephosphotransferase)/0.443
4riyADPEpidermal growth factor receptor2.7.10.10.443
4rjeFNRLactate oxidase/0.443
5aluHD2Bifunctional epoxide hydrolase 23.1.3.760.443
5cflC2EStimulator of interferon genes protein/0.443
5fknTDCTetracycline repressor protein class D/0.443
1bygSTUTyrosine-protein kinase CSK/0.442
1cqp803Integrin alpha-L/0.442
1i2lDCSAminodeoxychorismate lyase4.1.3.380.442
1u54ACPActivated CDC42 kinase 1/0.442
1ybmNAPUncharacterized protein At5g02240/0.442
2bu8ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.442
2bxmIMNSerum albumin/0.442
2dsiSAHDiphthine synthase/0.442
2gjnFMNNitronate monooxygenase1.13.12.160.442
2of4979Tyrosine-protein kinase Lck2.7.10.20.442
2prbCOAAminoglycoside 6-N-acetyltransferase type Ib11/0.442
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.442
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.442
2w8rADPSuccinate-semialdehyde dehydrogenase, mitochondrial1.2.1.240.442
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.442
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.442
3cukFADD-amino-acid oxidase1.4.3.30.442
3gwfFADCyclohexanone monooxygenase/0.442
3iaeD7KBenzaldehyde lyase/0.442
3il1B5DGlutamate receptor 2/0.442
3imeBZ2Pantothenate synthetase6.3.2.10.442
3mflDHYProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.442
3mflDHYProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.442
3pb3SAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.442
3qiyQI1Botulinum neurotoxin type A3.4.24.690.442
4jxzATPGlutamine--tRNA ligase6.1.1.180.442
4rrxLURProstaglandin G/H synthase 21.14.99.10.442
4u0oMTALipoyl synthase 2/0.442
4yl2FMNLactate oxidase/0.442
5aacVGHALK tyrosine kinase receptor2.7.10.10.442
1ek5NADUDP-glucose 4-epimerase/0.441
1hfqMOTDihydrofolate reductase1.5.1.30.441
1kp2ATPArgininosuccinate synthase6.3.4.50.441
1rw8580TGF-beta receptor type-12.7.11.300.441
1uy7PU4Heat shock protein HSP 90-alpha/0.441
1v9aSAHUncharacterized protein/0.441
1vyrFMNPentaerythritol tetranitrate reductase/0.441
2e07SAHDiphthine synthase/0.441
2gtnLIEMitogen-activated protein kinase 14/0.441
2hayFMNPutative NAD(P)H-flavin oxidoreductase/0.441
2w3bNDPDihydrofolate reductase1.5.1.30.441
2y60M8FIsopenicillin N synthase1.21.3.10.441
3ac1KZITyrosine-protein kinase Lck2.7.10.20.441
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
3i2834NBifunctional epoxide hydrolase 23.3.2.100.441
3jzdNADMaleylacetate reductase/0.441
3maaFKPAdenylate cyclase type 2/0.441
3maaFKPAdenylate cyclase type 5/0.441
3mdvCL6Cholesterol 24-hydroxylase/0.441
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.441
3p82FMNPentaerythritol tetranitrate reductase/0.441
3q95ESLEstrogen receptor/0.441
3sopGDPNeuronal-specific septin-3/0.441
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.441
3w78CBDFMN-dependent NADH-azoreductase/0.441
4dc0NDPPutative ketoacyl reductase1.3.10.441
4e07ACPPlasmid partitioning protein ParF/0.441
4fcq2N6Heat shock protein HSP 90-alpha/0.441
4iafADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4k81GTPGTPase HRas/0.441
4kcfAKMFAD-dependent oxidoreductase/0.441
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4tmcFMNOld yellow enzyme/0.441
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.441
4y8wSTRSteroid 21-hydroxylase/0.441
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.441
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.441
4zohFADPutative oxidoreductase FAD-binding subunit/0.441
5bylGCPBifunctional AAC/APH2.3.10.441
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.440
1h50FMNPentaerythritol tetranitrate reductase/0.440
1j4jACOAcetyltransferase2.3.10.440
1m8gNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.440
1qvnFRIInterleukin-2/0.440
1r2jFADFkbI/0.440
1vcfFMNIsopentenyl-diphosphate delta-isomerase/0.440
1x2hLPALipoate-protein ligase A6.3.1.200.440
1ykdCMPAdenylate cyclase/0.440
2cduFADNADH oxidase/0.440
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.440
2eixFADNADH-cytochrome b5 reductase/0.440
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.440
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.440
2olqATPPhosphoenolpyruvate carboxykinase (ATP)/0.440
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.440
2q4bNAPUncharacterized protein At5g02240/0.440
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.440
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
3vv8B02Beta-secretase 13.4.23.460.440
3zuyTCHTransporter/0.440
4dkv0KWEnvelope glycoprotein gp160/0.440
4g2fC07Ephrin type-A receptor 32.7.10.10.440
4iadADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.440
4kwhNAPReductase homolog/0.440
4mv8ACPBiotin carboxylase6.3.4.140.440
4qms1N1Serine/threonine-protein kinase 242.7.11.10.440