Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2dsi | SAH | Diphthine synthase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2dsi | SAH | Diphthine synthase | / | 1.000 | |
| 2p5c | SAH | Diphthine synthase | / | 0.841 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.838 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.809 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.805 | |
| 2eeq | SAH | Diphthine synthase | / | 0.803 | |
| 2p6k | SAH | Diphthine synthase | / | 0.795 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.784 | |
| 2p6i | SAH | Diphthine synthase | / | 0.783 | |
| 2e17 | SAH | Diphthine synthase | / | 0.779 | |
| 2eni | SAH | Diphthine synthase | / | 0.771 | |
| 2ejk | SAH | Diphthine synthase | / | 0.769 | |
| 2e15 | SAH | Diphthine synthase | / | 0.767 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.760 | |
| 2hut | SAH | Diphthine synthase | / | 0.758 | |
| 2owk | SAH | Diphthine synthase | / | 0.757 | |
| 2owu | SAH | Diphthine synthase | / | 0.756 | |
| 2p5f | SAH | Diphthine synthase | / | 0.755 | |
| 2dxx | SAH | Diphthine synthase | / | 0.754 | |
| 2pck | SAH | Diphthine synthase | / | 0.745 | |
| 2e7r | SAH | Diphthine synthase | / | 0.744 | |
| 2dsg | SAH | Diphthine synthase | / | 0.742 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.742 | |
| 2egs | SAH | Diphthine synthase | / | 0.725 | |
| 2p2x | SAH | Diphthine synthase | / | 0.724 | |
| 2owg | SAH | Diphthine synthase | / | 0.722 | |
| 2dxv | SAH | Diphthine synthase | / | 0.715 | |
| 2z6r | SAH | Diphthine synthase | / | 0.711 | |
| 2el0 | SAH | Diphthine synthase | / | 0.706 | |
| 1wng | SAH | Diphthine synthase | / | 0.702 | |
| 2eh2 | SAH | Diphthine synthase | / | 0.699 | |
| 2emr | SAH | Diphthine synthase | / | 0.698 | |
| 2dxw | SAH | Diphthine synthase | / | 0.696 | |
| 2e08 | SAH | Diphthine synthase | / | 0.695 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.691 | |
| 2emu | SAH | Diphthine synthase | / | 0.690 | |
| 2ehl | SAH | Diphthine synthase | / | 0.689 | |
| 2p6d | SAH | Diphthine synthase | / | 0.682 | |
| 2pcg | SAH | Diphthine synthase | / | 0.681 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.678 | |
| 2p9d | SAH | Diphthine synthase | / | 0.678 | |
| 2huv | SAH | Diphthine synthase | / | 0.676 | |
| 2e8h | SAH | Diphthine synthase | / | 0.669 | |
| 2e8r | SAH | Diphthine synthase | / | 0.666 | |
| 2ele | SAH | Diphthine synthase | / | 0.660 | |
| 2e8s | SAH | Diphthine synthase | / | 0.658 | |
| 2egb | SAH | Diphthine synthase | / | 0.657 | |
| 2pcm | SAH | Diphthine synthase | / | 0.655 | |
| 2huq | SAH | Diphthine synthase | / | 0.651 | |
| 2pch | SAH | Diphthine synthase | / | 0.651 | |
| 2pca | SAH | Diphthine synthase | / | 0.650 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.649 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.649 | |
| 1vce | SAH | Diphthine synthase | / | 0.648 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.639 | |
| 2dsh | SAH | Diphthine synthase | / | 0.633 | |
| 2eka | SAH | Diphthine synthase | / | 0.628 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.626 | |
| 2e07 | SAH | Diphthine synthase | / | 0.624 | |
| 2e8q | SAH | Diphthine synthase | / | 0.624 | |
| 2hux | SAH | Diphthine synthase | / | 0.623 | |
| 2pci | SAH | Diphthine synthase | / | 0.622 | |
| 2ejj | SAH | Diphthine synthase | / | 0.618 | |
| 2el3 | SAH | Diphthine synthase | / | 0.614 | |
| 2egl | SAH | Diphthine synthase | / | 0.611 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.607 | |
| 2eld | SAH | Diphthine synthase | / | 0.605 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.601 | |
| 2e4n | SAH | Diphthine synthase | / | 0.600 | |
| 2owv | SAH | Diphthine synthase | / | 0.591 | |
| 2p6l | SAH | Diphthine synthase | / | 0.579 | |
| 2e16 | SAH | Diphthine synthase | / | 0.573 | |
| 2owf | SAH | Diphthine synthase | / | 0.572 | |
| 2dek | SAH | Diphthine synthase | / | 0.570 | |
| 2ejz | SAH | Diphthine synthase | / | 0.569 | |
| 2en5 | SAH | Diphthine synthase | / | 0.563 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.562 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.556 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.518 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.499 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.498 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.496 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.490 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.489 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.488 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.488 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.488 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.480 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.480 | |
| 3vqs | JT1 | Genome polyprotein | / | 0.480 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.478 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.476 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.476 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.474 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.474 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.473 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.473 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.473 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.472 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.472 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.471 | |
| 4pl0 | ANP | Microcin-J25 export ATP-binding/permease protein McjD | / | 0.471 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.469 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.469 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.469 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.469 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.468 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.468 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.468 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.468 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.468 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.467 | |
| 2y3s | TIR | TamL | / | 0.467 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.467 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.466 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.466 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.466 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.466 | |
| 3ieu | GDP | GTPase Era | / | 0.465 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.464 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.464 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.463 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.463 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.463 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.463 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.462 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.461 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.461 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.461 | |
| 2y65 | ADP | Kinesin heavy chain | / | 0.461 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.461 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.461 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.460 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.460 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.459 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.459 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.459 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.459 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.458 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.458 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.458 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.458 | |
| 3p2e | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.458 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.458 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.458 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.457 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.457 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.457 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.456 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.456 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.456 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.456 | |
| 4asu | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.456 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.456 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.455 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.455 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.455 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.455 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.454 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.454 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.454 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.454 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.454 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.453 | |
| 1j3k | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.453 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.453 | |
| 3bc3 | OPT | Cathepsin L1 | 3.4.22.15 | 0.453 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.453 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.453 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.452 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.452 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.452 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.452 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.452 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.452 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.452 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.451 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.451 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.451 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 1ptj | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.451 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.451 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.451 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.451 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.451 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.451 | |
| 1ep3 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.450 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.450 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.450 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.450 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.450 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.449 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.449 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.449 | |
| 2xc3 | RT8 | Steroid C26-monooxygenase | 1.14.13.141 | 0.449 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.449 | |
| 3u9e | COA | Lmo1369 protein | / | 0.449 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.449 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.449 | |
| 4irn | FAD | AnaB | / | 0.449 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.449 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.448 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.448 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.447 | |
| 1xl5 | 190 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.447 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.447 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.447 | |
| 3zuy | TCH | Transporter | / | 0.447 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.447 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.447 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.446 | |
| 1eio | GCH | Gastrotropin | / | 0.446 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.446 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.446 | |
| 2fgj | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.446 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.446 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.446 | |
| 3a3g | DLZ | Lumazine protein | / | 0.446 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3so9 | 017 | Pol protein | / | 0.446 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.446 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.445 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 1xef | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.445 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.445 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.445 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.445 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.445 | |
| 3pb3 | SAH | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.445 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.445 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.445 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4xr9 | NAD | CalS8 | / | 0.445 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 1hbv | GAN | Gag-Pol polyprotein | / | 0.444 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.444 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.444 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.444 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 3kgc | LY7 | Glutamate receptor 2 | / | 0.444 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.444 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.444 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.444 | |
| 3zkp | ERB | Erythromycin C-12 hydroxylase | 1.14.13.154 | 0.444 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.444 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.444 | |
| 4ips | 1G4 | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.444 | |
| 1bmf | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 1bmf | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.443 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.443 | |
| 1rv1 | IMZ | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.443 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.443 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.443 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.443 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.443 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.442 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.442 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.442 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.442 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.442 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.442 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.442 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.442 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.442 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.442 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4i8z | G08 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.442 | |
| 4okn | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.442 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.442 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.441 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.441 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.441 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.441 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2z54 | AB1 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 2zno | S44 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.441 | |
| 3f7z | 34O | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 3ih0 | ANP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.441 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.441 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 4ig0 | 1FG | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.441 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.440 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.440 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.440 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.440 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.440 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.440 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.440 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.440 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 3mk6 | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.440 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.440 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.440 | |
| 3suf | SUE | Polyprotein | / | 0.440 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.440 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.440 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.440 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.440 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.440 |