sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2dg9 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2dg9 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 1.000 | |
| 4dh0 | MR8 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.665 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.659 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.641 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.621 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.613 | |
| 1a7x | FKA | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.598 | |
| 1bkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.591 | |
| 1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.591 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.589 | |
| 2fke | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.587 | |
| 1fkl | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.586 | |
| 1fki | SB1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.582 | |
| 1c9h | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1B | 5.2.1.8 | 0.580 | |
| 2dg3 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.579 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.576 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.576 | |
| 4dz2 | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.576 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.570 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.566 | |
| 1j4h | SUB | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.564 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.563 | |
| 1fkj | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.561 | |
| 4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.561 | |
| 1fkh | SBX | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.560 | |
| 4qt3 | RAP | Peptidylprolyl isomerase | / | 0.558 | |
| 3o5r | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.552 | |
| 1fkd | 818 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.549 | |
| 1fkg | SB3 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.545 | |
| 1q6i | FK5 | FKBP-type peptidyl-prolyl cis-trans isomerase FkpA | 5.2.1.8 | 0.544 | |
| 4drp | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.541 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.536 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.521 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.518 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.509 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.503 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.500 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.498 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.497 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.497 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.495 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.490 | |
| 1qin | GIP | Lactoylglutathione lyase | 4.4.1.5 | 0.489 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.489 | |
| 4n1g | CEI | Obelin | / | 0.489 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.487 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.487 | |
| 4boe | CLR | Japanin | / | 0.487 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.486 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.486 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.483 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.482 | |
| 3phc | IM5 | Purine nucleoside phosphorylase | / | 0.482 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.481 | |
| 2r0n | TGC | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.480 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.479 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.478 | |
| 1qip | GNB | Lactoylglutathione lyase | 4.4.1.5 | 0.478 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.477 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.477 | |
| 3l7g | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.477 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.476 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.476 | |
| 4nqg | CZH | Mitrocomin | / | 0.475 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.474 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.474 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.473 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.472 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.472 | |
| 4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.472 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.472 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.472 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.471 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.471 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.470 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.470 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.469 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.469 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.469 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.469 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.468 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.468 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.468 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.467 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.467 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.466 | |
| 1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.466 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.466 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.466 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3h59 | H59 | Genome polyprotein | 2.7.7.48 | 0.466 | |
| 1jf0 | CZH | Obelin | / | 0.465 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.465 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.464 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.464 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.464 | |
| 2z4z | SC0 | Geranylgeranyl pyrophosphate synthase | / | 0.464 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.464 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.463 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.463 | |
| 3lzz | GDP | Uncharacterized protein | / | 0.462 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.462 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.462 | |
| 4kc1 | WS1 | Histo-blood group ABO system transferase | / | 0.462 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.461 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.461 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.461 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.461 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.460 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.460 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.459 | |
| 1rxj | BNI | Streptavidin | / | 0.459 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.459 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.459 | |
| 4e2w | JHZ | Methyltransferase | / | 0.459 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.459 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.458 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.458 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.458 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.458 | |
| 3vrb | FTN | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.458 | |
| 3vrb | FTN | Cytochrome b-large subunit | / | 0.458 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.458 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.457 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.457 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.457 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.457 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.457 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.457 | |
| 1c7o | PPG | Hemolysin | / | 0.456 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.456 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.456 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.456 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.456 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.456 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.456 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.456 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.455 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.455 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.455 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.455 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.455 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3c1o | NAP | Eugenol synthase | / | 0.455 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.455 | |
| 4kc2 | WS2 | Histo-blood group ABO system transferase | / | 0.455 | |
| 5dv2 | C5P | CCR4-NOT transcription complex subunit 6-like | 3.1.13.4 | 0.455 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.455 | |
| 2isc | 223 | Purine nucleoside phosphorylase, putative | / | 0.454 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.454 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 4rel | KMP | Glycosyltransferase | / | 0.454 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.454 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.453 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.453 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.453 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.453 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.452 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 1s36 | CEI | Obelin | / | 0.452 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.452 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.452 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.452 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.452 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.452 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.452 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.452 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 4iah | 1DX | Alr2278 protein | / | 0.452 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.452 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.452 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.451 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.451 | |
| 2gg2 | U12 | Methionine aminopeptidase | / | 0.451 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.451 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.451 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.451 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.451 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.451 | |
| 4e31 | JHZ | Methyltransferase | / | 0.451 | |
| 4iae | 1DX | Alr2278 protein | / | 0.451 | |
| 4mm7 | 29J | Na(+):neurotransmitter symporter (Snf family) | / | 0.451 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.450 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.450 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 3vax | PLP | Uncharacterized protein | / | 0.450 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.450 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.450 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.450 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.450 | |
| 1el4 | CTZ | Obelin | / | 0.449 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 1ry8 | RUT | Aldo-keto reductase family 1 member C3 | / | 0.449 | |
| 1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.449 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2b82 | ADN | Class B acid phosphatase | 3.1.3.2 | 0.449 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.449 | |
| 2jj8 | AZZ | Deoxynucleoside kinase | / | 0.449 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.449 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.449 | |
| 3ojg | HL4 | Phosphotriesterase | / | 0.449 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.449 | |
| 1fml | RTL | Retinol dehydratase | / | 0.448 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.448 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.448 | |
| 1pwu | GM6 | Lethal factor | 3.4.24.83 | 0.448 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.448 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.448 | |
| 3b78 | NAD | Exotoxin A | 2.4.2.36 | 0.448 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.448 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.448 | |
| 4dch | 4DC | Glucokinase | 2.7.1.2 | 0.448 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.448 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.448 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.448 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.447 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 1rd7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1sui | FRE | Caffeoyl-CoA O-methyltransferase | 2.1.1.104 | 0.447 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2p99 | YE6 | Methionine aminopeptidase | / | 0.447 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.447 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.446 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.446 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.446 | |
| 4h0x | NAD | Iota toxin component Ia | / | 0.446 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.446 | |
| 4mm9 | FVX | Na(+):neurotransmitter symporter (Snf family) | / | 0.446 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.446 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1lke | DOG | Bilin-binding protein | / | 0.445 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3ju8 | NAD | N-succinylglutamate 5-semialdehyde dehydrogenase | 1.2.1.71 | 0.445 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.445 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.445 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.445 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.445 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.444 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.444 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.444 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.444 | |
| 3nxt | D2E | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.444 | |
| 3zm6 | 2GN | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.444 | |
| 4fal | 0T0 | Aldo-keto reductase family 1 member C3 | / | 0.444 | |
| 4hcy | 0YN | Transketolase | / | 0.444 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.444 | |
| 1b8o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1qy2 | IPZ | Major urinary protein 1 | / | 0.443 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.443 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.443 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.443 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.443 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.443 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.442 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.442 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.442 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.442 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.442 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.442 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.441 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.441 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.441 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.441 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3cow | 52H | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3r1r | ATP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.441 | |
| 3uel | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.441 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.441 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.441 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.441 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.440 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.440 | |
| 2v9c | MRE | FMN-dependent NADH-azoreductase 1 | / | 0.440 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2z78 | H86 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 3eku | CY9 | Actin-5C | / | 0.440 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 5ilw | URI | Ribosome inactivating protein | / | 0.440 |