sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2d3u | CCT | Polyprotein |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2d3u | CCT | Polyprotein | / | 1.000 | |
| 2o5d | VR1 | Genome polyprotein | 2.7.7.48 | 0.646 | |
| 3phe | C9A | RNA-directed RNA polymerase | / | 0.609 | |
| 1nhv | 154 | Genome polyprotein | 2.7.7.48 | 0.568 | |
| 4jty | 1NV | Genome polyprotein | 2.7.7.48 | 0.564 | |
| 4ju2 | 1O0 | Genome polyprotein | 2.7.7.48 | 0.564 | |
| 2gir | NN3 | Genome polyprotein | 2.7.7.48 | 0.545 | |
| 3cj3 | SX4 | Genome polyprotein | 2.7.7.48 | 0.542 | |
| 4ju1 | 1NZ | Genome polyprotein | 2.7.7.48 | 0.541 | |
| 4ju4 | 1O3 | Genome polyprotein | 2.7.7.48 | 0.532 | |
| 4j0a | 1JL | Genome polyprotein | 2.7.7.48 | 0.530 | |
| 4jvq | 1ML | Genome polyprotein | 2.7.7.48 | 0.523 | |
| 4jtw | 1NU | Genome polyprotein | 2.7.7.48 | 0.505 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.500 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.497 | |
| 1p93 | DEX | Glucocorticoid receptor | / | 0.494 | |
| 1e1q | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.490 | |
| 4ho9 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.490 | |
| 4j06 | 1JG | Genome polyprotein | 2.7.7.48 | 0.489 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.483 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.483 | |
| 5f5r | ANP | Heat shock protein 75 kDa, mitochondrial | / | 0.483 | |
| 1y9r | 1CA | Mineralocorticoid receptor | / | 0.482 | |
| 1zdw | FLV | Prenyltransferase | / | 0.482 | |
| 2a3i | C0R | Mineralocorticoid receptor | / | 0.482 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.482 | |
| 2wu5 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.482 | |
| 2wu5 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.482 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.481 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.481 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.481 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.480 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.479 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.479 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.478 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.478 | |
| 5dif | GNP | GTP-binding nuclear protein Ran | / | 0.478 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.477 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.477 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.476 | |
| 4kwh | NAP | Reductase homolog | / | 0.476 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.476 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.475 | |
| 2abi | 1CA | Mineralocorticoid receptor | / | 0.475 | |
| 3gcn | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.474 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.474 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.474 | |
| 2p2x | SAH | Diphthine synthase | / | 0.473 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.473 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.473 | |
| 3ru0 | SFG | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.473 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.473 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.472 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.472 | |
| 2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.471 | |
| 2w17 | I19 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 4kov | KOV | Uncharacterized protein | / | 0.471 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.471 | |
| 1khr | VIR | Streptogramin A acetyltransferase | 2.3.1 | 0.470 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 2wu2 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.470 | |
| 2wu2 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.470 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.469 | |
| 2igy | A2T | Plasmepsin 2 | / | 0.469 | |
| 4kox | CLS | Uncharacterized protein | / | 0.469 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.469 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.468 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1e2n | RCA | Thymidine kinase | / | 0.467 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.467 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.467 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.467 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.467 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.467 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.467 | |
| 1jx0 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.466 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.466 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.466 | |
| 2wep | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.466 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.466 | |
| 4azm | T4B | Fatty acid-binding protein, epidermal | / | 0.466 | |
| 4e31 | JHZ | Methyltransferase | / | 0.466 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.465 | |
| 2jj1 | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.465 | |
| 2jj1 | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.465 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.465 | |
| 4hxn | 1A7 | Bromodomain-containing protein 4 | / | 0.465 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.464 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.464 | |
| 1z2n | ADP | Inositol-tetrakisphosphate 1-kinase | 2.7.1.134 | 0.464 | |
| 2xtz | GSP | Guanine nucleotide-binding protein alpha-1 subunit | / | 0.464 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.464 | |
| 3t0z | ATP | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.463 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.463 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 3mnp | DEX | Glucocorticoid receptor | / | 0.463 | |
| 4a6e | ASE | Acetylserotonin O-methyltransferase | 2.1.1.4 | 0.463 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.463 | |
| 5ifi | PRX | Acetyl-coenzyme A synthetase | / | 0.463 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.462 | |
| 2toh | HBI | Tyrosine 3-monooxygenase | 1.14.16.2 | 0.462 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 2wge | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.462 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.462 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.462 | |
| 3i6r | J5Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.462 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.462 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1eyq | NAR | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.461 | |
| 1jqi | CAA | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.461 | |
| 1psd | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.461 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.461 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.461 | |
| 3c6t | M14 | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 3dd1 | 25D | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.461 | |
| 3fqk | 79Z | Genome polyprotein | 2.7.7.48 | 0.461 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.461 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.460 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.460 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2y3f | BTN | Streptavidin | / | 0.460 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.460 | |
| 3qzy | FAD | FAD-linked sulfhydryl oxidase | / | 0.460 | |
| 4qbi | AP5 | Adenylate kinase | / | 0.460 | |
| 4uyg | 73B | Bromodomain-containing protein 2 | / | 0.460 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.460 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.459 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.459 | |
| 4jic | FMN | GTN Reductase | / | 0.459 | |
| 4kot | CE3 | Uncharacterized protein | / | 0.459 | |
| 4lcg | 1WM | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.459 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.459 | |
| 1dd6 | MCI | Metallo-beta-lactamase type 2 | / | 0.458 | |
| 1fnd | A2P | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.458 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.458 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.458 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.458 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.458 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.458 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.458 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 4bmp | FMN | Protein NrdI | / | 0.458 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.458 | |
| 5hpy | GDP | Transforming protein RhoA | / | 0.458 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 1r2j | FAD | FkbI | / | 0.457 | |
| 2xp2 | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.457 | |
| 2ydx | STL | Methionine adenosyltransferase 2 subunit beta | / | 0.457 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.457 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.457 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4ajb | TAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.457 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.457 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.457 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.457 | |
| 4qjl | COA | Phosphopantetheinyl transferase, PptII | / | 0.457 | |
| 1hk2 | T44 | Serum albumin | / | 0.456 | |
| 1n0u | SO1 | Elongation factor 2 | / | 0.456 | |
| 1rp4 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.456 | |
| 1rti | HEF | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.456 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 4at5 | MUJ | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.456 | |
| 4bqw | QNM | Egl nine homolog 1 | / | 0.456 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.456 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.456 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.456 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1qy8 | RDI | Endoplasmin | / | 0.455 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.455 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2am9 | TES | Androgen receptor | / | 0.455 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2hai | PFI | Polyprotein | / | 0.455 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.455 | |
| 3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.455 | |
| 4dve | BTN | Biotin transporter BioY | / | 0.455 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4k8a | K8A | Focal adhesion kinase 1 | 2.7.10.2 | 0.455 | |
| 4xye | NAD | Formate dehydrogenase | / | 0.455 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.454 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.454 | |
| 1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.454 | |
| 1jm6 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.454 | |
| 1nen | DNT | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.454 | |
| 1nen | DNT | Succinate dehydrogenase cytochrome b556 subunit | / | 0.454 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.454 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.454 | |
| 2byc | FMN | Blue-light receptor of the BLUF-family | / | 0.454 | |
| 2e20 | B4P | Propionate kinase | / | 0.454 | |
| 2wd4 | TBV | Ascorbate peroxidase | / | 0.454 | |
| 2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.454 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.454 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.454 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.454 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.454 | |
| 4c9w | VGH | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.454 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.454 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 4koy | CSC | Uncharacterized protein | / | 0.454 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.453 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.453 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2ds1 | 1CD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.453 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.453 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.453 | |
| 3kc0 | 2T5 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.453 | |
| 3pd4 | A3G | Threonine--tRNA ligase | 6.1.1.3 | 0.453 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.453 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.453 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3t10 | ACP | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.453 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.453 | |
| 4e2w | JHZ | Methyltransferase | / | 0.453 | |
| 4ek8 | 16K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4ict | 1ED | Mycocyclosin synthase | 1.14.21.9 | 0.453 | |
| 4iq7 | 1G9 | Mycocyclosin synthase | 1.14.21.9 | 0.453 | |
| 4jld | ADP | Adenylate kinase | / | 0.453 | |
| 4n4t | 2GV | Tankyrase-1 | 2.4.2.30 | 0.453 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.453 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.453 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.453 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.452 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.452 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.452 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.452 | |
| 1mq4 | ADP | Aurora kinase A | 2.7.11.1 | 0.452 | |
| 1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.452 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.452 | |
| 1t7f | DHT | Androgen receptor | / | 0.452 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1yc3 | 4BC | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 2bgj | FAD | NADPH:ferredoxin reductase | / | 0.452 | |
| 2bxm | IMN | Serum albumin | / | 0.452 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.452 | |
| 2rtn | IMI | Streptavidin | / | 0.452 | |
| 2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.452 | |
| 3c50 | ADP | Rhodopsin kinase | / | 0.452 | |
| 3nhf | VVV | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.452 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.452 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.452 | |
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 0.452 | |
| 4el9 | AFE | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.452 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.452 | |
| 4s26 | SAH | Phosphomethylpyrimidine synthase, chloroplastic | 4.1.99.17 | 0.452 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.452 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.452 | |
| 5fa1 | C5P | Putative N-acetyl glucosaminyl transferase | / | 0.452 | |
| 1e2j | THM | Thymidine kinase | / | 0.451 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 1l4h | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.451 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.451 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.451 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.451 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.451 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 3g1o | RF1 | HTH-type transcriptional regulator EthR | / | 0.451 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.451 | |
| 3zr7 | OR8 | Progesterone receptor | / | 0.451 | |
| 4c73 | TLH | 3-oxoacyl-ACP synthase | / | 0.451 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.451 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.451 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.451 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1kr2 | TAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.450 | |
| 1sdm | ADP | Kinesin heavy chain-like protein | / | 0.450 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.450 | |
| 1yt0 | ADP | Endoplasmin | / | 0.450 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.450 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.450 | |
| 2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.450 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.450 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.450 | |
| 3h23 | B54 | Dihydropteroate synthase | / | 0.450 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.450 | |
| 3kb0 | A8S | Abscisic acid receptor PYL2 | / | 0.450 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.450 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.450 | |
| 3znq | SS8 | D-amino-acid oxidase | 1.4.3.3 | 0.450 | |
| 4apu | OR8 | Progesterone receptor | / | 0.450 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.450 | |
| 4eom | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4g8b | HL6 | Alpha/beta hydrolase fold protein | / | 0.450 | |
| 4j0r | 1H2 | Bromodomain-containing protein 4 | / | 0.450 | |
| 4k3n | 1OT | M17 leucyl aminopeptidase | / | 0.450 | |
| 4uoh | ADP | Nucleoside diphosphate kinase | / | 0.450 | |
| 4ys0 | ADP | Protein translocase subunit SecA | / | 0.450 | |
| 5cb5 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.450 | |
| 5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.450 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.449 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.449 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.449 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1szc | CNA | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.449 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.449 | |
| 2bxo | OPB | Serum albumin | / | 0.449 | |
| 2fie | A74 | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.449 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.449 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.449 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.449 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2vtl | LZ5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.449 | |
| 3frz | AG0 | Genome polyprotein | 2.7.7.48 | 0.449 | |
| 3ha7 | B32 | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.449 | |
| 3mpt | 1GK | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3n3b | FMN | Protein NrdI | / | 0.449 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.449 | |
| 4iah | 1DX | Alr2278 protein | / | 0.449 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.449 | |
| 4nhm | UN9 | Prolyl 3,4-dihydroxylase TPA1 | 1.14.11 | 0.449 | |
| 4p6x | HCY | Glucocorticoid receptor | / | 0.449 | |
| 4qvh | COA | Phosphopantetheinyl transferase PptT (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrier protein]pantetheinephosphotransferase) | / | 0.449 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.449 | |
| 4zhi | ADP | Kinesin-like protein KIF11 | / | 0.449 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.448 | |
| 1t79 | DHT | Androgen receptor | / | 0.448 | |
| 2egs | SAH | Diphthine synthase | / | 0.448 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.448 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.448 | |
| 3pah | XDE | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.448 | |
| 3t1k | ANP | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4deg | 0JJ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.448 | |
| 4kos | 4KO | Uncharacterized protein | / | 0.448 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.448 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.448 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.448 | |
| 4o74 | R78 | Bromodomain-containing protein 4 | / | 0.448 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.448 | |
| 4uda | DEX | Mineralocorticoid receptor | / | 0.448 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.448 | |
| 4ztv | TA7 | Anthranilate phosphoribosyltransferase | / | 0.448 | |
| 5da9 | AGS | Uncharacterized protein | / | 0.448 | |
| 5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.448 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.447 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.447 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.447 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2g44 | T3O | Estrogen receptor | / | 0.447 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.447 | |
| 2nn7 | M29 | Carbonic anhydrase 1 | 4.2.1.1 | 0.447 | |
| 2p2b | PRX | Acetyl-coenzyme A synthetase | / | 0.447 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.447 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 2z4b | DC8 | Estrogen receptor beta | / | 0.447 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 3m6p | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.447 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.447 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.447 | |
| 4cmf | PXG | Uncharacterized protein | / | 0.447 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.447 | |
| 4kow | CFX | Uncharacterized protein | / | 0.447 | |
| 4obe | GDP | GTPase KRas | / | 0.447 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.447 | |
| 1a8t | 061 | Metallo-beta-lactamase type 2 | / | 0.446 | |
| 1cgk | NAR | Chalcone synthase 2 | 2.3.1.74 | 0.446 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1eet | BFU | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 1jsc | TPP | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.446 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.446 | |
| 1t7t | DHT | Androgen receptor | / | 0.446 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.446 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2g1m | 4HG | Egl nine homolog 1 | / | 0.446 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.446 | |
| 2q7k | TES | Androgen receptor | / | 0.446 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 2xvv | 9DN | Serum albumin | / | 0.446 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.446 | |
| 3i0r | RT3 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3rpy | 27Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3zbn | COA | 3-ketoacyl-CoA thiolase-like protein | / | 0.446 | |
| 4b7p | 9UN | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.446 | |
| 4ivo | ACJ | Protoporphyrinogen oxidase | 1.3.3.4 | 0.446 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.446 | |
| 4l0o | PLP | Cystathionine gamma-synthase | 2.5.1.48 | 0.446 | |
| 4mr6 | 1K0 | Bromodomain-containing protein 2 | / | 0.446 | |
| 5k0s | 0OU | Methionine--tRNA ligase | / | 0.446 | |
| 5kbw | RBF | Riboflavin transporter RibU | / | 0.446 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 1bgq | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.445 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.445 | |
| 1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.445 | |
| 1sir | NBC | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.445 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.445 | |
| 2egb | SAH | Diphthine synthase | / | 0.445 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 2qpy | DHT | Androgen receptor | / | 0.445 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.445 | |
| 2xfo | XCG | Amine oxidase [flavin-containing] B | 1.4.3.4 | 0.445 | |
| 2zfa | FMN | Lactate oxidase | / | 0.445 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.445 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.445 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.445 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 4c3r | ACP | Aurora kinase A | 2.7.11.1 | 0.445 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 4kou | C04 | Uncharacterized protein | / | 0.445 | |
| 4nyw | 2O3 | CREB-binding protein | / | 0.445 | |
| 4pah | LNR | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.445 | |
| 4psx | COA | Histone acetyltransferase type B catalytic subunit | / | 0.445 | |
| 4qtn | NNR | Nicotinamide riboside transporter PnuC | / | 0.445 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.445 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.445 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.445 | |
| 5fkl | TDC | Tetracycline repressor protein class D | / | 0.445 | |
| 1cq8 | PY6 | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 1l4m | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.444 | |
| 1lru | BB2 | Peptide deformylase | 3.5.1.88 | 0.444 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.444 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 1t65 | DHT | Androgen receptor | / | 0.444 | |
| 1typ | NAP | Trypanothione reductase | 1.8.1.12 | 0.444 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.444 | |
| 2q7i | TES | Androgen receptor | / | 0.444 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.444 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3fl9 | TOP | Dihydrofolate reductase | / | 0.444 | |
| 3jzi | JZL | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 3mtl | FEF | Cyclin-dependent kinase 16 | 2.7.11.22 | 0.444 | |
| 3rdq | DTB | Streptavidin | / | 0.444 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.444 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.444 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.444 | |
| 4gvj | ADP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.444 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.444 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.444 | |
| 4qjk | COA | Phosphopantetheinyl transferase PptT (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrier protein]pantetheinephosphotransferase) | / | 0.444 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.444 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.444 | |
| 1bfd | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.443 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.443 | |
| 1df8 | BTN | Streptavidin | / | 0.443 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.443 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.443 | |
| 1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.443 | |
| 1qtq | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.443 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.443 | |
| 2ejk | SAH | Diphthine synthase | / | 0.443 | |
| 2fum | MIX | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.443 | |
| 2gnf | Y27 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.443 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 2vw5 | BC6 | ATP-dependent molecular chaperone HSP82 | / | 0.443 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.443 | |
| 3ce3 | 1FN | Hepatocyte growth factor receptor | 2.7.10.1 | 0.443 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.443 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.443 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.443 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
| 3s1a | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.443 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.443 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.443 | |
| 3zc5 | W9Z | Hepatocyte growth factor receptor | 2.7.10.1 | 0.443 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 4d9t | 0JG | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.443 | |
| 4gqi | M49 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.443 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.443 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.443 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 4yau | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 5ahs | COA | Acyl-CoA dehydrogenase | / | 0.443 | |
| 5c03 | AGS | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.443 | |
| 5d12 | G97 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.443 | |
| 5hq8 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.443 | |
| 1mvc | BM6 | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.442 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 1z0d | GDP | Ras-related protein Rab-5C | / | 0.442 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.442 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.442 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.442 | |
| 2g0g | SP0 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2i51 | FMN | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding | / | 0.442 | |
| 2imk | GTX | AGAP009194-PA | / | 0.442 | |
| 2jiz | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.442 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.442 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.442 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.442 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.442 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.442 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.442 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.442 | |
| 3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.442 | |
| 3ox2 | 79X | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 3q0u | LL3 | HTH-type transcriptional regulator EthR | / | 0.442 | |
| 3qtw | X3A | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3r7w | GNP | GTP-binding protein GTR2 | / | 0.442 | |
| 3s2p | PMU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3stj | UNK_UNK_UNK_UNK_UNK | Periplasmic pH-dependent serine endoprotease DegQ | 3.4.21.107 | 0.442 | |
| 3x1z | GNP | Ras-related protein Rap-1b | / | 0.442 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4c6u | TLG | 3-oxoacyl-ACP synthase | / | 0.442 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4e5k | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.442 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 4ere | 0R2 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.442 | |
| 4fk6 | 0UJ | Tyrosine-protein kinase JAK1 | / | 0.442 | |
| 4hus | VIR | Virginiamycin A acetyltransferase | 2.3.1 | 0.442 | |
| 4ike | ADP | Adenylate kinase | / | 0.442 | |
| 4jv3 | N32 | Beta-ketoacyl synthase | / | 0.442 | |
| 4k37 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.442 | |
| 4nhy | PD2 | Prolyl 3-hydroxylase OGFOD1 | 1.14.11 | 0.442 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.442 | |
| 5kf1 | COA | Predicted acetyltransferase | / | 0.442 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1l7x | 700 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.441 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.441 | |
| 1sqn | NDR | Progesterone receptor | / | 0.441 | |
| 1ws1 | BB2 | Peptide deformylase 1 | / | 0.441 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.441 | |
| 2bp1 | NDP | Aflatoxin B1 aldehyde reductase member 2 | / | 0.441 | |
| 2eck | ADP | Adenylate kinase | / | 0.441 | |
| 2i5n | UQ1 | Reaction center protein L chain | / | 0.441 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.441 | |
| 2ncd | ADP | Protein claret segregational | / | 0.441 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.441 | |
| 2p2j | PRX | Acetyl-coenzyme A synthetase | / | 0.441 | |
| 2v95 | HCY | Corticosteroid-binding globulin | / | 0.441 | |
| 2vfz | UPF | N-acetyllactosaminide alpha-1,3-galactosyltransferase | / | 0.441 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.441 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.441 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 3eku | CY9 | Actin-5C | / | 0.441 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.441 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3mfl | DHY | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.441 | |
| 3mfl | DHY | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.441 | |
| 3mno | DEX | Glucocorticoid receptor | / | 0.441 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.441 | |
| 3niz | ADP | Cdc2-like CDK2/CDC28 like protein kinase | / | 0.441 | |
| 3nny | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 3uxe | 465 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.441 | |
| 4bn1 | ADP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 4ct2 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4gbe | SAH | DNA adenine methylase | 2.1.1.72 | 0.441 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.441 | |
| 4img | NGF | N-acetylneuraminate lyase | / | 0.441 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.441 | |
| 4kko | 1RE | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.441 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.441 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.441 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1e1l | NAP | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.440 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.440 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.440 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 1um0 | FMN | Chorismate synthase | / | 0.440 | |
| 1zyd | ATP | eIF-2-alpha kinase GCN2 | / | 0.440 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.440 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.440 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.440 | |
| 2i80 | G1L | D-alanine--D-alanine ligase | / | 0.440 | |
| 2pan | TDP | Glyoxylate carboligase | 4.1.1.47 | 0.440 | |
| 2piu | DHT | Androgen receptor | / | 0.440 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
| 2rkg | AB1 | Pol protein | / | 0.440 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2vtn | LZ7 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2w8y | NDR | Progesterone receptor | / | 0.440 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.440 | |
| 3e39 | FMN | Nitroreductase | / | 0.440 | |
| 3g5k | BB2 | Peptide deformylase, mitochondrial | 3.5.1.88 | 0.440 | |
| 3i58 | 7NA | 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | / | 0.440 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.440 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.440 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.440 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 4ba5 | PXG | Probable aminotransferase | / | 0.440 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.440 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.440 | |
| 4udc | DEX | Glucocorticoid receptor | / | 0.440 | |
| 4z38 | FMN | MlnA | / | 0.440 | |
| 5f1c | ATP | Uncharacterized protein | / | 0.440 |